GO:0014889

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Name muscle atrophy
Categary Process
Go Slim No
Go Link GO:0014889
Unique Molecular Interactions 41
Total Molecular Interactions 48
Total Single Events 587
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for muscle atrophy. They are ordered first by their pain relevance and then by number of times they were reported for muscle atrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
2 INT94091 Binding of Pnoc and Tbce 1 0.03 0.19 1.19
3 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
4 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87
5 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85
6 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
7 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
8 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
9 INT52820 Oprd1 Regulation of NR3C1 1 0.02 0.17 0.61
10 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51
11 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51
12 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
13 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
14 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
15 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43
16 INT227566 NR3C1 Positive_regulation of RS1 1 0.01 0 0.4
17 INT227568 NR3C1 Positive_regulation of HTR1A 1 0.00 0 0.4
18 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
19 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37
20 INT254121 Binding of Tbce and Aliq1 1 0.00 0.69 0.2
21 INT79521 Ptger1 Negative_regulation of Positive_regulation of Tbce 1 0.00 0.57 0.2
22 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
23 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
24 INT146744 Binding of NR3C1 and PLA2G4A 1 0.26 0.25 0.15
25 INT276813 NR3C1 Regulation of Gene_expression of Hgs 1 0.03 1.09 0.13
26 INT276767 NR3C1 Regulation of Gene_expression of UTS2R 1 0.00 1.09 0.13
27 INT68493 Pomc Positive_regulation of NR3C1 1 0.02 0 0.12
28 INT259636 Binding of Tbce and COPD 1 0.04 1 0.11
29 INT352030 Binding of NR3C1 and IL2 1 0.15 0.5 0.11
30 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
31 INT227565 NR3C1 Positive_regulation of UFM1 1 0.00 0.07 0.08
32 INT340553 Pik3r1 Regulation of Gene_expression of Fbxo32 1 0.04 0.52 0.07
33 INT352217 Tlr4 Positive_regulation of Binding of Tbce 1 0.03 0.8 0.07
34 INT340564 Akt1 Regulation of Gene_expression of Fbxo32 1 0.05 0.52 0.07
35 INT278613 NR3C1 Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
36 INT324865 Tbce Positive_regulation of Gene_expression of ecs 1 0.06 0.35 0.05
37 INT352216 Binding of Tlr4 and Tbce 1 0.01 0.3 0.04
38 INT231117 Tlr4 Positive_regulation of Transcription of Fbxo32 1 0.15 0.14 0.03
39 INT246144 FBXO32 Regulation of C2 1 0.08 0 0
40 INT218300 Gtf3a Positive_regulation of Gene_expression of Fbxo32 1 0.00 0.09 0
41 INT328626 Binding of TBCE and MUC16 1 0.15 0.79 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for muscle atrophy. They are ordered first by their pain relevance and then by number of times they were reported in muscle atrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33
2 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1
3 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
4 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93
5 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
6 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
7 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
8 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
9 INT3306 Localization of Tbce 16 0.12 8.24 5.71
10 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
11 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
12 INT10474 Regulation of Tbce 6 0.22 4.18 5.11
13 INT52818 Localization of NR3C1 13 0.69 7.65 4.57
14 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31
15 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
16 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
17 INT228047 Negative_regulation of Gene_expression of Tbce 4 0.06 2.33 2.48
18 INT205187 Localization of TBCE 3 0.14 4.11 2.47
19 INT228048 Positive_regulation of Positive_regulation of Tbce 3 0.05 2.47 2.35
20 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
21 INT46100 Negative_regulation of TBCE 7 0.50 1.96 2.24
22 INT125281 Positive_regulation of Positive_regulation of NR3C1 1 0.49 0 2.11
23 INT51316 Regulation of NR3C1 7 0.51 4.23 2.09
24 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
25 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
26 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
27 INT61939 Negative_regulation of Positive_regulation of Tbce 5 0.06 4.82 1.82
28 INT228052 Positive_regulation of Negative_regulation of Tbce 1 0.05 1.56 1.82
29 INT20394 Binding of Tbce 12 0.06 5.47 1.78
30 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
31 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
32 INT205189 Gene_expression of TBCE 12 0.25 9.67 1.19
33 INT228050 Negative_regulation of Negative_regulation of Tbce 1 0.04 0.96 1.02
34 INT228038 Positive_regulation of Gene_expression of Tbce 3 0.07 2.02 1.01
35 INT166449 Positive_regulation of Gene_expression of NR3C1 4 0.68 3.73 0.99
36 INT157686 Gene_expression of Fbxo32 14 0.75 8.68 0.9
37 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
38 INT246180 Gene_expression of FBXO32 10 0.65 4.21 0.79
39 INT205188 Positive_regulation of Gene_expression of TBCE 5 0.19 2.14 0.74
40 INT165838 Positive_regulation of TBCE 3 0.07 1.3 0.71
41 INT68486 Transcription of NR3C1 4 0.20 0.19 0.69
42 INT257447 Binding of TBCE 4 0.08 4.68 0.66
43 INT350004 Positive_regulation of Binding of Tbce 1 0.07 1.86 0.65
44 INT7576 Positive_regulation of Transcription of Nr3c1 1 0.19 0.3 0.62
45 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59
46 INT170768 Regulation of Gene_expression of NR3C1 3 0.42 2.61 0.58
47 INT83353 Negative_regulation of Binding of NR3C1 3 0.24 1.09 0.57
48 INT166103 Positive_regulation of Negative_regulation of TBCE 1 0.43 0.24 0.56
49 INT165839 Negative_regulation of Positive_regulation of TBCE 1 0.03 0.51 0.49
50 INT290850 Regulation of Positive_regulation of Nr3c1 1 0.12 0.75 0.47
51 INT103896 Negative_regulation of Gene_expression of NR3C1 1 0.09 0.83 0.45
52 INT46101 Regulation of TBCE 2 0.11 1.53 0.43
53 INT52815 Regulation of Negative_regulation of Nr3c1 1 0.08 0.05 0.43
54 INT175024 Positive_regulation of Localization of NR3C1 1 0.10 0.5 0.41
55 INT157690 Negative_regulation of Gene_expression of Fbxo32 4 0.41 1.36 0.4
56 INT246182 Positive_regulation of Gene_expression of FBXO32 2 0.49 1.55 0.4
57 INT38685 Regulation of Binding of NR3C1 2 0.61 0.59 0.4
58 INT218294 Positive_regulation of Gene_expression of Fbxo32 7 0.49 5.84 0.34
59 INT226172 Transcription of Fbxo32 3 0.52 1.56 0.31
60 INT3307 Negative_regulation of Localization of Tbce 1 0.07 0.27 0.3
61 INT226167 Positive_regulation of Transcription of Fbxo32 3 0.45 1.42 0.28
62 INT246201 Negative_regulation of Gene_expression of FBXO32 5 0.41 1.27 0.25
63 INT281616 Binding of FBXO32 1 0.36 1.08 0.24
64 INT218287 Positive_regulation of Fbxo32 3 0.49 0.51 0.22
65 INT157691 Regulation of Gene_expression of Fbxo32 1 0.31 0.73 0.22
66 INT79657 Positive_regulation of Transcription of NR3C1 1 0.17 0.09 0.19
67 INT79655 Positive_regulation of Phosphorylation of NR3C1 1 0.17 0.09 0.19
68 INT79662 Phosphorylation of NR3C1 1 0.30 0.09 0.19
69 INT317595 Negative_regulation of Transcription of Nr3c1 1 0.05 0.14 0.18
70 INT20395 Negative_regulation of Binding of Tbce 1 0.00 0.17 0.17
71 INT352211 Positive_regulation of Localization of Tbce 1 0.05 0.93 0.16
72 INT323241 Positive_regulation of Positive_regulation of TBCE 1 0.04 0.55 0.15
73 INT276881 Regulation of FBXO32 2 0.44 1.71 0.13
74 INT268931 Positive_regulation of Regulation of Nr3c1 1 0.10 0.34 0.13
75 INT231093 Negative_regulation of Fbxo32 3 0.41 0.55 0.12
76 INT350003 Regulation of Gene_expression of Tbce 1 0.07 0 0.12
77 INT281614 Regulation of Binding of FBXO32 1 0.44 0.54 0.09
78 INT231096 Negative_regulation of Positive_regulation of Fbxo32 1 0.41 0 0.09
79 INT276883 Positive_regulation of FBXO32 7 0.67 2.63 0.07
80 INT246196 Regulation of Gene_expression of FBXO32 2 0.44 0.35 0.07
81 INT280628 Regulation of Transcription of NR3C1 1 0.09 0 0.07
82 INT246197 Regulation of Phosphorylation of FBXO32 1 0.27 0.14 0.06
83 INT246184 Phosphorylation of FBXO32 1 0.49 0.14 0.06
84 INT134850 Positive_regulation of Negative_regulation of Nr3c1 1 0.02 0 0.04
85 INT281612 Negative_regulation of Positive_regulation of FBXO32 1 0.42 0.22 0.04
86 INT231100 Negative_regulation of Transcription of Fbxo32 1 0.42 0.14 0.03
87 INT274092 Negative_regulation of Gene_expression of TBCE 1 0.08 1.17 0.03
88 INT276878 Transcription of FBXO32 2 0.69 0.3 0
89 INT257449 Regulation of Gene_expression of TBCE 1 0.09 0.85 0
90 INT226189 Protein_catabolism of Fbxo32 1 0.18 0.64 0
91 INT281613 Protein_catabolism of FBXO32 1 0.64 0.11 0
92 INT276877 Positive_regulation of Positive_regulation of FBXO32 1 0.27 0.34 0
93 INT245628 Regulation of Localization of Nr3c1 1 0.15 0 0
94 INT328631 Transcription of TBCE 1 0.20 0.81 0
95 INT281615 Negative_regulation of FBXO32 1 0.41 0.15 0
96 INT281617 Regulation of Positive_regulation of FBXO32 1 0.44 0 0
97 INT351070 Binding of Fbxo32 1 0.02 0.61 0
98 INT351071 Positive_regulation of Binding of Fbxo32 1 0.03 0.68 0
99 INT246190 Localization of FBXO32 1 0.39 0 0
100 INT281611 Positive_regulation of Transcription of FBXO32 1 0.67 0 0
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