GO:0014898

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Name cardiac muscle hypertrophy in response to stress
Categary Process
Go Slim No
Go Link GO:0014898
Unique Molecular Interactions 18
Total Molecular Interactions 19
Total Single Events 221
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cardiac muscle hypertrophy in response to stress. They are ordered first by their pain relevance and then by number of times they were reported for cardiac muscle hypertrophy in response to stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
2 INT52459 Binding of SUCLA2 and HEY2 1 0.01 0.09 0.21
3 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
4 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
5 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
6 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
7 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
8 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
9 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
10 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
11 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0
12 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 0.21 0 0
13 INT290441 Mef2c Regulation of Mef2b 1 0.09 0.11 0
14 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0
15 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
16 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
17 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
18 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cardiac muscle hypertrophy in response to stress. They are ordered first by their pain relevance and then by number of times they were reported in cardiac muscle hypertrophy in response to stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
2 INT137532 Negative_regulation of HEY2 1 0.31 1.69 3.18
3 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
4 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
5 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
6 INT148385 Positive_regulation of HEY2 1 0.38 1.09 0.62
7 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
8 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
9 INT238560 Regulation of Mef2c 9 0.45 2.12 0.33
10 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
11 INT202355 Transcription of Mef2c 3 0.69 0.6 0.21
12 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18
13 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
14 INT277602 Binding of Mef2c 10 0.39 4.35 0.16
15 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
16 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
17 INT290404 Positive_regulation of Negative_regulation of Mef2c 1 0.50 0.72 0.08
18 INT277578 Regulation of Negative_regulation of Mef2c 2 0.45 1.17 0.07
19 INT290417 Positive_regulation of Gene_expression of Mef2c 1 0.50 1.25 0.06
20 INT290407 Positive_regulation of Binding of Mef2c 1 0.44 0.93 0.04
21 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
22 INT290419 Regulation of Gene_expression of Mef2c 1 0.62 0.41 0.03
23 INT277248 Localization of HEY2 1 0.73 0.5 0.03
24 INT290399 Negative_regulation of Gene_expression of Mef2c 1 0.59 0.59 0.03
25 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
26 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
27 INT290400 Regulation of Regulation of Mef2c 1 0.45 0.24 0
28 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
29 INT290429 Negative_regulation of Negative_regulation of Mef2c 1 0.37 0.05 0
30 INT290425 Negative_regulation of Binding of Mef2c 1 0.37 0 0
31 INT290409 Negative_regulation of Transcription of Mef2c 1 0.43 0.08 0
32 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
33 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
34 INT277587 Localization of Mef2c 1 0.65 0.43 0
35 INT341052 Gene_expression of HEY2 1 0.04 0.12 0
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