GO:0014910

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Name regulation of smooth muscle cell migration
Categary Process
Go Slim No
Go Link GO:0014910
Unique Molecular Interactions 243
Total Molecular Interactions 310
Total Single Events 3609
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of smooth muscle cell migration. They are ordered first by their pain relevance and then by number of times they were reported for regulation of smooth muscle cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
2 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
3 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
4 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
5 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
6 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
7 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
8 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
9 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
10 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
11 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
12 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
13 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
14 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
15 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
16 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
17 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
18 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
19 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
20 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
21 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
22 INT314037 THL Negative_regulation of Localization of Plau 1 0.17 1.64 0.99
23 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
24 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
25 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
26 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
27 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
28 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
29 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
30 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
31 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
32 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
33 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
34 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
35 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
36 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
37 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
38 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
39 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
40 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
41 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
42 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
43 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
44 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72
45 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
46 INT77689 Binding of Ace and Tenc1 1 0.28 0.65 0.7
47 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
48 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
49 INT180961 Binding of MOCS1 and PLAU 1 0.00 0.61 0.67
50 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65
51 INT189020 Tacr1 Positive_regulation of Pla2g1b 1 0.14 0.13 0.65
52 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
53 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
54 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
55 INT167859 Tac1 Regulation of Gene_expression of Tacr1 1 0.09 0 0.6
56 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
57 INT69898 Binding of Olfr19 and Tacr1 1 0.00 0.1 0.55
58 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
59 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
60 INT15273 Calca Regulation of Tacr1 1 0.22 0 0.5
61 INT157003 Gal Regulation of Localization of Tacr1 1 0.01 0.1 0.49
62 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
63 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
64 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
65 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
66 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
67 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
68 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
69 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
70 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38
71 INT113553 Negative_regulation of Binding of PLAU and PLAUR 1 0.36 0.87 0.37
72 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
73 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
74 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
75 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
76 INT98066 Binding of Plau and Plau 1 0.00 1.49 0.34
77 INT207408 Il6 Positive_regulation of Gene_expression of Tacr1 1 0.08 0.56 0.33
78 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
79 INT207409 Ptger2 Positive_regulation of Gene_expression of Tacr1 1 0.04 0.56 0.32
80 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
81 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
82 INT207114 Binding of Plau and Plaur 1 0.19 0.7 0.29
83 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
84 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29
85 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
86 INT75108 Binding of Tac2 and Tacr1 1 0.18 0.1 0.29
87 INT113558 Negative_regulation of NFKB1 Negative_regulation of Localization of PLAU 1 0.41 0.97 0.29
88 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
89 INT124340 Tacr1 Positive_regulation of Tac2 1 0.48 0 0.27
90 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
91 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
92 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25
93 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
94 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
95 INT278581 Tacr2 Positive_regulation of Tacr1 1 0.55 0 0.24
96 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
97 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
98 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24
99 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
100 INT278578 Tacr3 Positive_regulation of Tacr1 1 0.55 0 0.24
101 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24
102 INT278570 Nka1 Positive_regulation of Tacr1 1 0.06 0 0.24
103 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22
104 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
105 INT65525 Tacr1 Regulation of Regulation of Spn 1 0.15 0.36 0.22
106 INT200637 Binding of Abpa and Ace 1 0.01 4.62 0.22
107 INT202183 PLAU Regulation of Protein_catabolism of PLAUR 1 0.11 1.25 0.21
108 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
109 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21
110 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
111 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21
112 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
113 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
114 INT345186 Lpar2 Positive_regulation of Gene_expression of Plau 1 0.05 2.2 0.2
115 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
116 INT314049 THL Negative_regulation of Gene_expression of Plau 1 0.20 2.91 0.19
117 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
118 INT169117 PLAU Regulation of Gene_expression of MMP9 1 0.47 0.49 0.17
119 INT169118 PLAU Regulation of Gene_expression of CSF2 1 0.41 0.49 0.17
120 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17
121 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
122 INT8164 Ace Positive_regulation of Gene_expression of Fos 1 0.24 0.32 0.16
123 INT258812 Sugt1 Positive_regulation of Ace 1 0.05 1.26 0.16
124 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
125 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
126 INT75058 Negative_regulation of ACE Negative_regulation of HHIP 1 0.25 0.43 0.15
127 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
128 INT307807 Ace Positive_regulation of ras 1 0.38 3 0.15
129 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
130 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
131 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14
132 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
133 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
134 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
135 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
136 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
137 INT332243 Pdgfa Positive_regulation of Stat1 1 0.06 0.52 0.14
138 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14
139 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
140 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
141 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
142 INT300512 Binding of Plau and Vtn 1 0.06 2.28 0.13
143 INT256020 Ace Negative_regulation of Gene_expression of Agtr2 1 0.03 0.37 0.13
144 INT256021 Ace Negative_regulation of Gene_expression of Agtrap 1 0.05 0.37 0.13
145 INT271478 Tacr1 Regulation of Binding of Mthfd1 1 0.09 0.48 0.13
146 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
147 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
148 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12
149 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12
150 INT43095 Binding of Ace and Mme 1 0.26 0 0.12
151 INT224455 Pdgfa Regulation of VEGFA 1 0.07 0.22 0.11
152 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11
153 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
154 INT171162 Negative_regulation of Ace Negative_regulation of Gene_expression of Ccl2 1 0.02 1.18 0.1
155 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
156 INT208939 Positive_regulation of Tacr1 Positive_regulation of Nfkb1 1 0.19 0 0.1
157 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
158 INT115717 TNF Regulation of Gene_expression of PLAU 1 0.49 0.56 0.09
159 INT104737 Ace Positive_regulation of Gene_expression of Ren1 1 0.35 0.09 0.09
160 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
161 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
162 INT344945 Negative_regulation of ACE Positive_regulation of REN 1 0.23 0.64 0.09
163 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
164 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
165 INT115718 TNF Regulation of PLAU 1 0.31 0.48 0.08
166 INT115719 IL1B Regulation of PLAU 1 0.49 0.48 0.08
167 INT179346 Pdgfa Positive_regulation of Positive_regulation of Mapk3 1 0.05 0.71 0.07
168 INT307805 Ace Positive_regulation of Ang 1 0.32 1.52 0.07
169 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
170 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 0.16 0.83 0.07
171 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 0.04 0.83 0.07
172 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
173 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
174 INT307806 Ace Positive_regulation of Agt 1 0.28 1.51 0.07
175 INT275800 Binding of Sh2d1a and Tacr1 1 0.01 0.29 0.07
176 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
177 INT179345 Pdgfa Positive_regulation of Mapk3 1 0.05 0.71 0.07
178 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 0.17 0.83 0.07
179 INT122480 Binding of SERPINE1 and PLAU 4 0.40 2.75 0.06
180 INT49112 Binding of SERPINB2 and PLAU 2 0.00 2.06 0.06
181 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
182 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
183 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
184 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
185 INT259635 Plau Positive_regulation of PLG 1 0.13 0.22 0.06
186 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06
187 INT200638 Binding of ACE and Agtr2 1 0.10 0.93 0.06
188 INT49113 Binding of CFI and PLAU 1 0.00 1.55 0.06
189 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06
190 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
191 INT200635 Binding of Ace and Spink1 1 0.37 1.4 0.05
192 INT29521 Ace Positive_regulation of ACE 1 0.19 0 0.04
193 INT251892 Binding of Plau and Naf1 1 0.07 0.06 0.04
194 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04
195 INT104736 Ace Positive_regulation of Ren1 1 0.35 0 0.04
196 INT179348 Pdgfa Positive_regulation of Binding of Pscs 1 0.04 0.38 0.03
197 INT348685 Positive_regulation of Mmp9 Positive_regulation of Protein_catabolism of Plau 1 0.10 0.27 0.03
198 INT179347 Pdgfa Positive_regulation of Pscs 1 0.04 0.38 0.03
199 INT288134 Pdgfa Regulation of Ifi35 1 0.01 0.78 0.03
200 INT179344 Pdgfa Positive_regulation of Binding of Jun 1 0.00 0.38 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of smooth muscle cell migration. They are ordered first by their pain relevance and then by number of times they were reported in regulation of smooth muscle cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
2 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
3 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
4 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
5 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
6 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
7 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
8 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
9 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
10 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
11 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
12 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
13 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08
14 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
15 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
16 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
17 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
18 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
19 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31
20 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
21 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
22 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
23 INT20664 Binding of ACE 60 0.48 35.27 9.16
24 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
25 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
26 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
27 INT389 Gene_expression of Ace 21 0.67 10.31 8.1
28 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
29 INT25958 Regulation of Ace 26 0.59 11.88 7.87
30 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46
31 INT42038 Localization of ACE 26 0.80 8.88 7.06
32 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
33 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
34 INT71116 Gene_expression of Plau 29 0.77 4.94 6.45
35 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
36 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
37 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
38 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
39 INT26477 Regulation of ACE 26 0.45 16.31 4.33
40 INT29327 Positive_regulation of Ace 13 0.67 8.79 4.33
41 INT387 Regulation of Ace 18 0.45 5.24 4.24
42 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
43 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
44 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
45 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
46 INT105222 Positive_regulation of Plau 18 0.54 8.52 3.5
47 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
48 INT71117 Positive_regulation of Gene_expression of Plau 9 0.69 0.22 2.92
49 INT107950 Regulation of Gene_expression of Tacr1 6 0.61 1.13 2.84
50 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
51 INT115464 Gene_expression of Plau 41 0.72 30.21 2.79
52 INT65126 Transcription of Tacr1 5 0.63 3.44 2.77
53 INT8652 Protein_catabolism of Ace 10 0.94 4.7 2.74
54 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
55 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
56 INT67884 Positive_regulation of PLAU 15 0.68 11.21 2.61
57 INT245286 Localization of Plau 6 0.66 9.56 2.58
58 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
59 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
60 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4
61 INT11357 Negative_regulation of Gene_expression of PLAU 10 0.56 5.3 2.38
62 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33
63 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
64 INT98898 Localization of Tacr1 6 0.72 2.47 2.25
65 INT388 Positive_regulation of Gene_expression of Ace 4 0.42 1.04 2.13
66 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
67 INT45646 Protein_catabolism of Ace 5 0.98 3.14 1.95
68 INT43084 Binding of Ace 10 0.46 4.7 1.93
69 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93
70 INT11364 Regulation of Gene_expression of PLAU 4 0.58 3.23 1.92
71 INT100874 Protein_catabolism of Plau 4 0.77 1.51 1.83
72 INT55606 Binding of Ace 14 0.37 10.73 1.82
73 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77
74 INT48813 Negative_regulation of Plau 12 0.44 3.46 1.66
75 INT115721 Positive_regulation of Gene_expression of PLAU 11 0.67 7.66 1.55
76 INT106359 Regulation of Plau 7 0.45 3.51 1.5
77 INT115463 Positive_regulation of Plau 13 0.47 8.47 1.49
78 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
79 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37
80 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
81 INT113567 Localization of PLAU 12 0.79 7.16 1.34
82 INT44145 Negative_regulation of Gene_expression of Ace 5 0.40 4.5 1.33
83 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
84 INT177840 Negative_regulation of PLAU 3 0.41 3.37 1.27
85 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
86 INT65124 Negative_regulation of Positive_regulation of Tacr1 3 0.53 0.9 1.18
87 INT122481 Binding of PLAU 10 0.36 6.1 1.16
88 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
89 INT88948 Localization of Ace 9 0.69 9.18 1.11
90 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99
91 INT100875 Regulation of Protein_catabolism of Plau 2 0.35 0.7 0.99
92 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
93 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
94 INT314024 Negative_regulation of Localization of Plau 1 0.18 1.27 0.94
95 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
96 INT93677 Transcription of PLAU 3 0.70 2.89 0.9
97 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
98 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
99 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
100 INT132587 Negative_regulation of Gene_expression of Tacr1 3 0.57 1.22 0.85
101 INT83995 Positive_regulation of Gene_expression of ACE 8 0.68 8.09 0.82
102 INT93676 Regulation of Transcription of PLAU 1 0.44 0.07 0.82
103 INT230803 Regulation of Negative_regulation of Ace 2 0.39 1.89 0.81
104 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
105 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
106 INT165240 Negative_regulation of Transcription of Tacr1 3 0.42 0.81 0.74
107 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7
108 INT113566 Negative_regulation of Localization of PLAU 4 0.55 2.7 0.67
109 INT113565 Regulation of PLAU 6 0.58 5.8 0.66
110 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
111 INT48816 Localization of Plau 7 0.47 1.2 0.62
112 INT72446 Negative_regulation of Binding of ACE 4 0.42 2.48 0.62
113 INT56045 Positive_regulation of Localization of ACE 3 0.69 1.38 0.6
114 INT200636 Regulation of Gene_expression of Ace 1 0.26 1.64 0.6
115 INT167854 Positive_regulation of Regulation of Tacr1 1 0.41 0 0.59
116 INT51159 Positive_regulation of Binding of Tacr1 1 0.34 0.17 0.59
117 INT167857 Positive_regulation of Localization of Tacr1 1 0.44 0 0.59
118 INT113568 Protein_catabolism of PLAU 5 0.94 4.79 0.57
119 INT99832 Regulation of Negative_regulation of Tacr1 2 0.27 1.28 0.56
120 INT51157 Regulation of Binding of Tacr1 1 0.31 0.2 0.56
121 INT115462 Positive_regulation of Gene_expression of Plau 14 0.65 7.35 0.53
122 INT98065 Binding of Plau 5 0.12 2.39 0.52
123 INT22333 Regulation of Negative_regulation of Ace 3 0.45 0.72 0.52
124 INT36764 Localization of Ace 7 0.80 1.53 0.51
125 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
126 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5
127 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
128 INT43091 Positive_regulation of Negative_regulation of Ace 3 0.30 1.51 0.48
129 INT219033 Regulation of Transcription of Tacr1 1 0.15 0.62 0.46
130 INT171150 Negative_regulation of Binding of Ace 2 0.17 2.67 0.44
131 INT44032 Regulation of Positive_regulation of Ace 1 0.38 0.1 0.43
132 INT175807 Protein_catabolism of Plau 2 0.28 1.14 0.39
133 INT114063 Negative_regulation of Localization of Ace 1 0.29 0.31 0.39
134 INT60040 Negative_regulation of Negative_regulation of Ace 6 0.43 3.64 0.38
135 INT181635 Positive_regulation of Protein_catabolism of ACE 1 0.15 0.41 0.38
136 INT77686 Transcription of Ace 2 0.65 2.65 0.37
137 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36
138 INT314033 Regulation of Protein_catabolism of Plau 1 0.12 1.03 0.36
139 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35
140 INT245290 Negative_regulation of Gene_expression of Plau 4 0.40 2.93 0.32
141 INT84195 Negative_regulation of Binding of Tacr1 1 0.02 0 0.32
142 INT332231 Positive_regulation of Positive_regulation of Pdgfa 1 0.16 0.83 0.31
143 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29
144 INT96863 Transcription of ACE 3 0.69 0.38 0.29
145 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29
146 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29
147 INT113391 Regulation of Positive_regulation of Tacr1 2 0.35 0.5 0.27
148 INT229358 Negative_regulation of Protein_catabolism of Ace 1 0.40 0.93 0.27
149 INT113563 Positive_regulation of Localization of PLAU 1 0.66 0.95 0.27
150 INT47070 Positive_regulation of Localization of Ace 2 0.32 0.55 0.26
151 INT229357 Regulation of Binding of Ace 1 0.43 0.86 0.26
152 INT123698 Positive_regulation of Positive_regulation of Plau 2 0.22 1.08 0.24
153 INT65003 Negative_regulation of Negative_regulation of Ace 5 0.37 3.45 0.23
154 INT333364 Negative_regulation of Positive_regulation of Pdgfa 1 0.03 0.99 0.22
155 INT125777 Positive_regulation of Negative_regulation of Plau 1 0.03 0.4 0.22
156 INT251885 Regulation of Gene_expression of Plau 5 0.42 1.83 0.21
157 INT307794 Negative_regulation of Gene_expression of Ace 7 0.48 5.95 0.2
158 INT180970 Positive_regulation of Binding of PLAU 1 0.26 0.4 0.19
159 INT69192 Positive_regulation of Positive_regulation of Ace 1 0.02 0 0.19
160 INT48812 Binding of Plau 2 0.20 0.15 0.18
161 INT108414 Negative_regulation of Regulation of ACE 1 0.43 0.67 0.17
162 INT44051 Positive_regulation of Protein_catabolism of Ace 1 0.41 0 0.16
163 INT332238 Regulation of Regulation of Pdgfa 1 0.14 0.94 0.16
164 INT205603 Regulation of Pdgfa 5 0.16 4.84 0.15
165 INT59791 Positive_regulation of Negative_regulation of Ace 3 0.49 0.57 0.13
166 INT155694 Phosphorylation of PDGFA 2 0.58 0.42 0.13
167 INT121978 Negative_regulation of Gene_expression of Plau 2 0.20 0.96 0.13
168 INT210396 Negative_regulation of Binding of PDGFA 1 0.02 1.6 0.13
169 INT327249 Positive_regulation of Transcription of Plau 1 0.08 0.83 0.13
170 INT327240 Transcription of Plau 1 0.09 0.83 0.13
171 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12
172 INT249970 Transcription of Ace 3 0.36 1.87 0.12
173 INT43092 Negative_regulation of Binding of Ace 1 0.31 0 0.12
174 INT171219 Regulation of Plau 9 0.42 1.04 0.11
175 INT79993 Positive_regulation of Positive_regulation of ACE 2 0.49 0.78 0.1
176 INT340501 Regulation of Transcription of Ace 1 0.10 0.84 0.1
177 INT180700 Regulation of Localization of Plau 1 0.25 0 0.1
178 INT340500 Negative_regulation of Transcription of Ace 1 0.10 0.78 0.07
179 INT249971 Positive_regulation of Transcription of Ace 1 0.35 0.47 0.06
180 INT128209 Positive_regulation of Regulation of Ace 1 0.42 0.4 0.06
181 INT48814 Regulation of Binding of Plau 1 0.05 0.1 0.05
182 INT42326 Negative_regulation of Regulation of Ace 1 0.15 0 0.05
183 INT230809 Positive_regulation of Localization of Ace 1 0.44 0.38 0.05
184 INT48815 Negative_regulation of Binding of Plau 1 0.05 0.09 0.04
185 INT286904 Regulation of Binding of PDGFA 1 0.30 0.74 0.04
186 INT348682 Transcription of Plau 1 0.31 0.29 0.04
187 INT102927 Negative_regulation of Localization of Ace 3 0.58 1 0.03
188 INT348681 Positive_regulation of Protein_catabolism of Plau 1 0.29 0.27 0.03
189 INT172787 Negative_regulation of Plau 2 0.11 1.46 0
190 INT337634 Regulation of Binding of PLAU 1 0.16 0.38 0
191 INT292120 Regulation of Regulation of PDGFA 1 0.12 0.93 0
192 INT270742 Negative_regulation of Phosphorylation of ACE 1 0.40 0.65 0
193 INT171228 Regulation of Regulation of Plau 1 0.08 0 0
194 INT347305 Negative_regulation of Positive_regulation of PDGFA 1 0.17 0.56 0
195 INT270740 Phosphorylation of ACE 1 0.76 0.65 0
196 INT251886 Negative_regulation of Regulation of Plau 1 0.40 0.37 0
197 INT316367 Negative_regulation of Transcription of Ace 1 0.40 0.22 0
198 INT307796 Positive_regulation of Positive_regulation of Ace 1 0.39 1.33 0
199 INT301931 Negative_regulation of Negative_regulation of PLAU 1 0.18 1.54 0
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