GO:0015037

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Name peptide disulfide oxidoreductase activity
Categary Function
Go Slim No
Go Link GO:0015037
Unique Molecular Interactions 26
Total Molecular Interactions 51
Total Single Events 141
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptide disulfide oxidoreductase activity. They are ordered first by their pain relevance and then by number of times they were reported for peptide disulfide oxidoreductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
2 INT210160 Binding of TNFRSF8 and TXN 1 0.47 4.16 0.48
3 INT100282 TXN Negative_regulation of Transcription of POMC 1 0.54 0.39 0.43
4 INT100279 TXN Negative_regulation of Gene_expression of HSP90B2P 1 0.13 0.3 0.24
5 INT100280 TXN Positive_regulation of Gene_expression of MC1R 1 0.33 0.22 0.24
6 INT100284 TXN Positive_regulation of Gene_expression of POMC 1 0.65 0 0.19
7 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
8 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1
9 INT169343 OXT Negative_regulation of Gene_expression of Txn1 1 0.00 0.58 0.08
10 INT145499 Txn1 Negative_regulation of Negative_regulation of Akt1 1 0.28 0.88 0.07
11 INT145500 Txn1 Negative_regulation of Gene_expression of Ros1 1 0.03 0.87 0.07
12 INT210146 Binding of EGFR and TXN 1 0.15 0.09 0.06
13 INT210155 TXN Positive_regulation of Gene_expression of TNFRSF8 1 0.49 0.22 0.05
14 INT210156 Binding of TNFSF8 and TXN 1 0.10 0.4 0.04
15 INT155239 PPARA Regulation of Txn1 1 0.02 0.18 0.04
16 INT155231 Positive_regulation of PPARA Positive_regulation of TXN 1 0.37 0.17 0.04
17 INT210154 TXN Regulation of Gene_expression of FASLG 1 0.09 0.23 0.03
18 INT210159 Binding of PRDX1 and TXN 1 0.21 0 0
19 INT210163 Binding of FAS and TXN 1 0.19 0 0
20 INT210162 TXN Negative_regulation of TNFRSF8 1 0.37 0.15 0
21 INT210153 Regulation of Binding of TNFRSF8 and TXN 1 0.44 0.49 0
22 INT210147 Binding of TXN and TNFRSF6B 1 0.01 0 0
23 INT302882 Positive_regulation of Binding of TXN and Alb 1 0.05 1.51 0
24 INT210150 TXN Regulation of TNFRSF8 1 0.26 0.2 0
25 INT210152 Positive_regulation of Binding of TNFRSF8 and TXN 1 0.49 0.49 0
26 INT210164 Binding of TXN and TXNRD1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptide disulfide oxidoreductase activity. They are ordered first by their pain relevance and then by number of times they were reported in peptide disulfide oxidoreductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138698 Gene_expression of Txn1 15 0.77 11.71 4.24
2 INT138701 Positive_regulation of Gene_expression of Txn1 10 0.50 9.16 4.03
3 INT69703 Gene_expression of TXN 20 0.71 3.57 2.01
4 INT100286 Localization of TXN 21 0.73 5.13 1.48
5 INT69705 Positive_regulation of TXN 8 0.63 2.35 0.89
6 INT210193 Binding of TXN 31 0.44 6.88 0.78
7 INT115293 Regulation of Gene_expression of TXN 2 0.19 0.78 0.73
8 INT228042 Positive_regulation of Txn1 1 0.14 0.65 0.68
9 INT138697 Negative_regulation of Gene_expression of Txn1 1 0.41 0.93 0.68
10 INT155236 Negative_regulation of TXN 5 0.53 0.66 0.46
11 INT210194 Positive_regulation of Gene_expression of TXN 1 0.46 1.17 0.43
12 INT100287 Regulation of TXN 2 0.41 0.62 0.42
13 INT271882 Protein_catabolism of TXN 1 0.09 0.17 0.31
14 INT210191 Positive_regulation of Positive_regulation of TXN 1 0.46 1.16 0.21
15 INT144866 Localization of Txn1 1 0.67 1.48 0.15
16 INT145498 Negative_regulation of Txn1 1 0.42 1.73 0.13
17 INT144867 Transcription of Txn1 1 0.57 0.77 0.08
18 INT144874 Regulation of Localization of Txn1 1 0.20 0.74 0.07
19 INT302881 Negative_regulation of Binding of TXN 1 0.05 1.43 0
20 INT210197 Positive_regulation of Binding of TXN 1 0.63 0.19 0
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