GO:0015056

From wiki-pain
Jump to: navigation, search
Name corticotrophin-releasing factor receptor activity
Categary Function
Go Slim No
Go Link GO:0015056
Unique Molecular Interactions 47
Total Molecular Interactions 66
Total Single Events 452
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for corticotrophin-releasing factor receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for corticotrophin-releasing factor receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
2 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
3 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
4 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
5 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
6 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
7 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
8 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64
9 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63
10 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
11 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56
12 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54
13 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
14 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
15 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
16 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
17 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
18 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36
19 INT59602 Crhr1 Positive_regulation of Localization of LH 1 0.25 0 0.33
20 INT356323 Binding of ac and Crhr1 1 0.01 0 0.32
21 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29
22 INT264782 Binding of CRH and CRHR1 1 0.02 0.06 0.28
23 INT98816 Crhr2 Positive_regulation of Negative_regulation of Ucn 1 0.33 0.09 0.28
24 INT180194 CRH Positive_regulation of CRHR2 1 0.02 0.24 0.27
25 INT180195 CRH Regulation of CRHR2 1 0.01 0.24 0.27
26 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25
27 INT100084 Binding of CRH and CRHR2 1 0.32 1.11 0.19
28 INT153322 CRH Positive_regulation of Positive_regulation of CRHR1 1 0.31 0.12 0.19
29 INT122192 Binding of Crhr2 and Ucn2 1 0.02 0.23 0.11
30 INT205031 Crh Positive_regulation of Crhr2 1 0.45 1.11 0.11
31 INT317774 CRHR1 Positive_regulation of Localization of POMC 1 0.05 0.55 0.11
32 INT205033 Ucn Positive_regulation of Crhr2 1 0.22 0.15 0.08
33 INT163410 CRX Positive_regulation of Gene_expression of Crhr2 1 0.02 0.94 0.05
34 INT163411 CRX Negative_regulation of Gene_expression of Crhr2 1 0.02 0.94 0.05
35 INT222469 Binding of Ucn and Crhr2 1 0.00 0 0.03
36 INT205032 Crh Regulation of Crhr1 1 0.21 0.84 0.03
37 INT264801 Binding of Crhr2 and UCN2 1 0.00 0 0.03
38 INT222502 Binding of Crhr1 and Ucn2 1 0.01 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for corticotrophin-releasing factor receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in corticotrophin-releasing factor receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
2 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
3 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
4 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
5 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
6 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
7 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
8 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
9 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
10 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
11 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53
12 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33
13 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
14 INT9752 Regulation of Localization of Crhr1 3 0.44 0.36 2.82
15 INT122187 Positive_regulation of Crhr2 3 0.58 2.46 2.56
16 INT101955 Gene_expression of Crhr2 6 0.64 3.62 2.31
17 INT142929 Regulation of Crhr2 1 0.44 1.28 1.73
18 INT205025 Positive_regulation of Positive_regulation of Crhr1 2 0.70 1.22 1.51
19 INT29667 Positive_regulation of CRHR1 6 0.54 1.09 1.5
20 INT93792 Binding of Crhr1 4 0.48 1.32 1.49
21 INT112934 Binding of Crhr1 7 0.46 2.69 1.39
22 INT101954 Binding of Crhr2 4 0.31 1.23 1.34
23 INT28888 Positive_regulation of Crhr2 6 0.68 3.8 1.23
24 INT140887 Binding of CRHR1 2 0.34 0.26 1.22
25 INT104040 Regulation of Crhr2 2 0.36 1.29 0.81
26 INT74324 Positive_regulation of Gene_expression of Crhr1 6 0.49 2.91 0.79
27 INT77256 Negative_regulation of Gene_expression of Crhr1 5 0.40 2.52 0.77
28 INT101952 Negative_regulation of Crhr2 1 0.17 0.97 0.77
29 INT290527 Positive_regulation of Localization of Crhr1 1 0.37 1.4 0.74
30 INT290534 Localization of Crhr1 1 0.56 1.4 0.74
31 INT117245 Gene_expression of CRHR1 3 0.51 3.45 0.73
32 INT7567 Negative_regulation of Transcription of Crhr1 1 0.37 0.48 0.71
33 INT28889 Transcription of Crhr2 2 0.64 1.13 0.66
34 INT7563 Regulation of Transcription of Crhr1 1 0.17 0.59 0.59
35 INT101949 Negative_regulation of Binding of Crhr2 1 0.24 0.6 0.55
36 INT356301 Negative_regulation of Positive_regulation of Crhr1 1 0.19 0.44 0.5
37 INT143392 Transcription of Crhr1 1 0.61 0.38 0.43
38 INT148784 Negative_regulation of Crhr2 2 0.40 0.76 0.42
39 INT100085 Binding of CRHR2 2 0.30 1.18 0.39
40 INT221086 Negative_regulation of CRHR1 3 0.31 0.71 0.37
41 INT144599 Gene_expression of Crhr2 3 0.49 2.16 0.36
42 INT121505 Regulation of Regulation of Crhr1 1 0.43 0.33 0.35
43 INT153296 Regulation of Gene_expression of Crhr1 2 0.39 0.72 0.34
44 INT140886 Gene_expression of CRHR2 1 0.03 0.22 0.33
45 INT247098 Localization of CRHR1 3 0.68 1.45 0.27
46 INT303591 Positive_regulation of Gene_expression of Crhr1 2 0.42 0.34 0.25
47 INT143393 Transcription of Crhr2 1 0.52 0.19 0.21
48 INT112935 Binding of Crhr2 1 0.32 0.33 0.17
49 INT140882 Positive_regulation of CRHR2 1 0.02 0.08 0.15
50 INT140885 Transcription of CRHR2 1 0.02 0.08 0.15
51 INT140884 Positive_regulation of Transcription of CRHR2 1 0.02 0.08 0.15
52 INT163408 Negative_regulation of Gene_expression of Crhr2 2 0.27 1.56 0.13
53 INT93793 Positive_regulation of Binding of Crhr1 1 0.48 0.34 0.13
54 INT285036 Localization of CRHR2 1 0.56 0.49 0.12
55 INT165756 Positive_regulation of Gene_expression of Crhr2 1 0.31 0.62 0.07
56 INT205027 Positive_regulation of Positive_regulation of Crhr2 1 0.58 0.14 0.07
57 INT165757 Positive_regulation of Positive_regulation of Crhr1 1 0.29 0.6 0.07
58 INT165755 Regulation of Gene_expression of Crhr2 1 0.28 0.62 0.07
59 INT205028 Regulation of Gene_expression of Crhr1 1 0.45 0.97 0
60 INT205029 Regulation of Gene_expression of Crhr2 1 0.22 1.03 0
61 INT205026 Regulation of Negative_regulation of Crhr1 1 0.45 0.72 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox