GO:0015075

From wiki-pain
Jump to: navigation, search
Name ion transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0015075
Unique Molecular Interactions 38
Total Molecular Interactions 45
Total Single Events 417
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for ion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105917 Binding of SLC22A6 and SLC22A8 2 0.31 0.34 1.67
2 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49
3 INT157063 SLC12A1 Negative_regulation of CALCRL 1 0.00 0.34 0.73
4 INT115811 Binding of Slc22a6 and Mtx1 1 0.02 0.17 0.65
5 INT115812 Binding of Slc22a8 and Mtx1 1 0.08 0.17 0.65
6 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
7 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
8 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5
9 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37
10 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36
11 INT111837 Binding of ABCB1 and SLC22A3 1 0.35 0 0.31
12 INT175017 Negative_regulation of Binding of REN and S100A6 1 0.13 0.45 0.29
13 INT175018 Positive_regulation of Binding of REN and S100A6 1 0.15 0.45 0.29
14 INT147385 Binding of TRPV1 and TRPV2 1 0.37 0 0.15
15 INT147386 Regulation of Binding of TRPV1 and TRPV2 1 0.45 0 0.15
16 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11
17 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1
18 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07
19 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
20 INT50079 Binding of NPPA and SLC12A1 1 0.01 0.42 0.07
21 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 0.10 0.88 0.06
22 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06
23 INT155789 Binding of SGCG and SLC22A5 1 0.40 0 0.06
24 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
25 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
26 INT266415 Binding of ROS1 and S100a6 1 0.02 0.82 0.03
27 INT197907 Dlst Regulation of S100a6 1 0.10 0 0
28 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0
29 INT197902 Regulation of Oxt Regulation of S100a6 1 0.08 0 0
30 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0
31 INT212413 SLC12A1 Regulation of PRKAB1 1 0.00 0 0
32 INT197913 Oxt Regulation of Gene_expression of S100a6 1 0.08 0 0
33 INT197904 Dlst Positive_regulation of Positive_regulation of S100a6 1 0.09 0 0
34 INT197898 Dlst Regulation of Gene_expression of S100a6 1 0.14 0 0
35 INT324340 Binding of SLC12A1 and Scr 1 0.00 1.42 0
36 INT197905 Oxt Regulation of S100a6 1 0.08 0 0
37 INT219634 Binding of NLRP1 and Slc22a6 1 0.26 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in ion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62
2 INT95099 Gene_expression of SLC22A8 14 0.67 1.59 5.14
3 INT95101 Binding of SLC22A8 6 0.48 0.75 5.07
4 INT95102 Localization of SLC22A8 3 0.75 0.69 4.24
5 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
6 INT96304 Gene_expression of Slc22a8 9 0.66 0.63 3.12
7 INT104134 Binding of SLC22A6 3 0.34 0.52 2.75
8 INT19157 Gene_expression of SLC22A6 5 0.71 1.39 2.18
9 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88
10 INT26369 Gene_expression of S100A6 19 0.65 5.39 1.81
11 INT145075 Localization of SLC22A5 1 0.08 0.18 1.75
12 INT145076 Gene_expression of SLC22A5 4 0.68 1.87 1.46
13 INT92405 Negative_regulation of Slc22a6 2 0.47 1.52 1.34
14 INT145074 Binding of SLC22A5 3 0.37 1.56 1.29
15 INT90829 Negative_regulation of SLC22A6 3 0.40 0.75 1.22
16 INT115810 Negative_regulation of Slc22a8 3 0.41 0.27 1.18
17 INT145077 Regulation of SLC22A5 2 0.19 3 1.1
18 INT123213 Negative_regulation of SLC22A8 2 0.35 1.43 1.05
19 INT293678 Positive_regulation of Gene_expression of S100A6 1 0.34 2.42 1.04
20 INT108805 Binding of Slc22a8 3 0.18 0.44 0.97
21 INT43919 Negative_regulation of S100A6 19 0.16 4.45 0.96
22 INT111838 Regulation of SLC22A3 1 0.38 0 0.94
23 INT90830 Localization of SLC22A6 3 0.69 0.86 0.89
24 INT155791 Transcription of SLC22A5 1 0.53 0 0.88
25 INT177997 Regulation of SLC22A4 2 0.20 3.88 0.86
26 INT168284 Localization of Slc22a8 1 0.78 0.1 0.82
27 INT81604 Transcription of SLC22A6 2 0.63 0.67 0.78
28 INT178004 Binding of SLC22A4 2 0.26 2.45 0.77
29 INT73433 Gene_expression of S100a6 10 0.71 2.74 0.76
30 INT178116 Phosphorylation of GJA1 7 0.80 4.09 0.74
31 INT117369 Gene_expression of SLC22A3 3 0.59 0.22 0.7
32 INT109468 Negative_regulation of SLC22A3 1 0.13 0.15 0.66
33 INT246207 Positive_regulation of GJA1 3 0.67 0.91 0.65
34 INT115809 Binding of Slc22a6 1 0.03 0.17 0.65
35 INT142953 Positive_regulation of Gene_expression of TRPV2 2 0.70 5.56 0.64
36 INT70515 Gene_expression of Slc22a6 7 0.78 1.26 0.63
37 INT90831 Negative_regulation of Gene_expression of SLC22A6 1 0.40 0.39 0.58
38 INT50084 Positive_regulation of SLC12A1 4 0.03 1.11 0.57
39 INT143162 Gene_expression of S100a6 7 0.78 5.86 0.49
40 INT329831 Positive_regulation of Positive_regulation of GJA1 1 0.49 0.58 0.48
41 INT192937 Positive_regulation of Gene_expression of GJA1 4 0.67 0.4 0.44
42 INT110498 Localization of S100a6 1 0.31 1.57 0.44
43 INT168285 Negative_regulation of Localization of Slc22a8 1 0.36 0 0.44
44 INT43387 Regulation of S100A6 2 0.15 0.4 0.4
45 INT95100 Transcription of SLC22A8 4 0.45 0.57 0.39
46 INT147225 Positive_regulation of Slc22a8 2 0.49 0 0.38
47 INT213648 Phosphorylation of S100A6 2 0.30 1.43 0.36
48 INT143165 Positive_regulation of S100a6 8 0.69 3.5 0.34
49 INT262284 Negative_regulation of Positive_regulation of Slc22a6 1 0.06 0.79 0.31
50 INT262299 Negative_regulation of Positive_regulation of SLC22A8 1 0.06 0.79 0.31
51 INT262283 Positive_regulation of Slc22a6 1 0.07 0.73 0.3
52 INT262300 Positive_regulation of SLC22A8 1 0.07 0.73 0.3
53 INT197585 Positive_regulation of S100a6 3 0.43 1.67 0.29
54 INT118439 Transcription of TRPV2 2 0.71 0.26 0.29
55 INT126820 Negative_regulation of Gene_expression of Slc22a6 2 0.26 0.85 0.26
56 INT262296 Negative_regulation of Transcription of SLC22A8 1 0.06 0.58 0.26
57 INT262292 Negative_regulation of Gene_expression of SLC22A8 1 0.06 0.58 0.26
58 INT262285 Negative_regulation of Transcription of Slc22a6 1 0.06 0.58 0.26
59 INT262286 Transcription of Slc22a6 1 0.09 0.58 0.26
60 INT143164 Positive_regulation of Gene_expression of S100a6 3 0.69 2.33 0.25
61 INT157905 Binding of TRPV2 1 0.31 0.91 0.25
62 INT128386 Transcription of Slc22a8 1 0.38 0 0.25
63 INT132951 Regulation of GJA1 2 0.57 0.79 0.24
64 INT247021 Binding of GJA1 6 0.47 0.91 0.23
65 INT118444 Positive_regulation of Transcription of TRPV2 1 0.44 0.26 0.21
66 INT73435 Negative_regulation of S100a6 1 0.21 0.26 0.2
67 INT136279 Positive_regulation of TRPV2 1 0.50 0 0.2
68 INT143163 Regulation of S100a6 2 0.45 1.47 0.18
69 INT186146 Negative_regulation of GJA1 2 0.41 1.29 0.18
70 INT178124 Positive_regulation of Phosphorylation of GJA1 2 0.65 1.21 0.18
71 INT131262 Transcription of SLC22A3 1 0.03 0 0.16
72 INT131267 Positive_regulation of Gene_expression of SLC22A3 1 0.02 0 0.16
73 INT50083 Binding of SLC12A1 2 0.01 1.01 0.15
74 INT50082 Positive_regulation of Binding of SLC12A1 1 0.02 0.3 0.15
75 INT293679 Positive_regulation of Positive_regulation of S100A6 2 0.24 1.19 0.14
76 INT209185 Regulation of Phosphorylation of GJA1 2 0.44 0.09 0.14
77 INT165954 Gene_expression of SLC12A1 3 0.55 1.32 0.1
78 INT197584 Binding of S100a6 2 0.14 0.81 0.09
79 INT209182 Regulation of Gene_expression of GJA1 1 0.57 0.09 0.09
80 INT188177 Localization of GJA1 2 0.75 0.07 0.07
81 INT178132 Negative_regulation of Gene_expression of GJA1 2 0.35 0.84 0.07
82 INT209187 Positive_regulation of Localization of GJA1 1 0.65 0.07 0.07
83 INT311813 Binding of S100A6 1 0.14 0.13 0.07
84 INT93164 Localization of TRPV2 2 0.74 0.07 0.05
85 INT185438 Gene_expression of SLC22A4 1 0.39 1.51 0.03
86 INT293673 Transcription of S100A6 1 0.38 0.15 0.03
87 INT197866 Binding of S100a6 2 0.41 0 0
88 INT197879 Positive_regulation of Binding of S100a6 1 0.42 0 0
89 INT209190 Negative_regulation of Negative_regulation of GJA1 1 0.40 0 0
90 INT178112 Negative_regulation of Phosphorylation of GJA1 1 0.18 1.09 0
91 INT77428 Negative_regulation of Positive_regulation of S100A6 1 0.15 0 0
92 INT327450 Negative_regulation of Gene_expression of S100A6 1 0.12 0.19 0
93 INT160111 Localization of Slc22a6 1 0.68 0 0
94 INT338257 Negative_regulation of SLC12A1 1 0.01 0.38 0
95 INT82588 Regulation of Gene_expression of S100A6 1 0.44 0.05 0
96 INT223292 Localization of SLC22A3 1 0.29 0.06 0
97 INT126821 Negative_regulation of Gene_expression of Slc22a8 1 0.17 0.27 0
98 INT197884 Transcription of S100a6 1 0.45 0 0
99 INT293674 Positive_regulation of Transcription of S100A6 1 0.28 0.15 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox