GO:0015171

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Name amino acid transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0015171
Unique Molecular Interactions 38
Total Molecular Interactions 58
Total Single Events 233
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for amino acid transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for amino acid transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95
2 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
3 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21
4 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
5 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
6 INT161481 Slc7a12 Regulation of Gene_expression of Il1b 1 0.14 1.21 0.77
7 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
8 INT349222 CSF2 Positive_regulation of Gene_expression of SLC7A7 1 0.17 0.4 0.13
9 INT329473 SLC7A7 Regulation of Ca2 1 0.04 0.1 0.13
10 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
11 INT329476 SLC7A7 Regulation of Gpr55 1 0.12 0.1 0.09
12 INT329474 Binding of SLC7A7 and Ca2 1 0.03 0.4 0.08
13 INT178969 Slc7a2 Regulation of Ins1 1 0.01 0.56 0.05
14 INT178968 Slc7a2 Negative_regulation of Glb1 1 0.02 1.77 0.05
15 INT256024 Binding of Agt and Slc1a5 1 0.01 0.36 0.05
16 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
17 INT349221 CSF2 Regulation of Gene_expression of SLC7A7 1 0.10 0.18 0.04
18 INT344317 PDPN Negative_regulation of VEGFA 1 0.08 0.67 0.03
19 INT344308 Positive_regulation of PDPN Negative_regulation of VEGFA 1 0.09 0.24 0.03
20 INT205989 Binding of SLC7A7 and PDAP1 1 0.02 1.77 0
21 INT329475 Binding of SLC7A7 and Gpr55 1 0.09 0.52 0
22 INT329478 SLC7A7 Positive_regulation of Ca2 1 0.04 0 0
23 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0
24 INT171757 Binding of MMP2 and SLC7A5 1 0.03 0.29 0
25 INT329454 SLC7A7 Positive_regulation of NA 1 0.01 0.09 0
26 INT349224 Binding of CSF2 and SLC7A7 1 0.12 0.38 0
27 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0
28 INT344319 MAPK8 Positive_regulation of PDPN 1 0.35 0.5 0
29 INT329455 SLC7A7 Negative_regulation of DNAH8 1 0.00 0 0
30 INT344307 PDPN Negative_regulation of Gene_expression of VEGFA 1 0.08 0.36 0
31 INT344318 PDPN Positive_regulation of Positive_regulation of RHOA 1 0.11 0.92 0
32 INT349223 CSF2 Positive_regulation of SLC7A7 1 0.17 0.3 0
33 INT344316 VEGFA Positive_regulation of PDPN 1 0.09 0.4 0
34 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0
35 INT178967 Slc7a2 Regulation of Localization of Ins1 1 0.01 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for amino acid transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in amino acid transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT40782 Gene_expression of Slc7a2 10 0.57 4.59 5
2 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
3 INT69554 Regulation of Slc7a11 4 0.12 1.02 3.68
4 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
5 INT40783 Localization of Slc7a2 1 0.62 0 1.25
6 INT205995 Gene_expression of SLC7A7 11 0.75 10.61 1.21
7 INT217990 Negative_regulation of Slc7a2 1 0.41 2.16 0.85
8 INT72971 Positive_regulation of Slc7a11 1 0.08 0.49 0.84
9 INT33195 Positive_regulation of Slc7a2 2 0.23 0 0.82
10 INT135816 Transcription of Slc7a2 1 0.54 0 0.81
11 INT135819 Positive_regulation of Transcription of Slc7a2 1 0.38 0 0.81
12 INT135821 Negative_regulation of Transcription of Slc7a2 1 0.32 0 0.81
13 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
14 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
15 INT84026 Positive_regulation of SLC7A7 8 0.67 3.12 0.33
16 INT318437 Negative_regulation of Pdpn 1 0.47 0.87 0.25
17 INT140204 Regulation of Slc1a5 1 0.36 0 0.19
18 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18
19 INT308962 Regulation of SLC7A7 3 0.16 1.2 0.18
20 INT329471 Positive_regulation of Gene_expression of SLC7A7 2 0.49 0.51 0.17
21 INT160121 Localization of PDPN 1 0.73 1.07 0.16
22 INT217991 Regulation of Slc7a2 1 0.19 0.44 0.16
23 INT205991 Negative_regulation of SLC7A7 9 0.41 1.81 0.12
24 INT329470 Localization of SLC7A7 3 0.73 0.32 0.08
25 INT205994 Transcription of SLC7A7 2 0.70 1.44 0.05
26 INT171766 Transcription of SLC7A5 1 0.06 0.43 0.05
27 INT349230 Positive_regulation of Positive_regulation of SLC7A7 1 0.39 0 0.05
28 INT349228 Positive_regulation of Transcription of SLC7A7 1 0.45 0 0.05
29 INT344332 Positive_regulation of Gene_expression of PDPN 1 0.58 0.72 0.04
30 INT344330 Phosphorylation of PDPN 1 0.53 0.15 0.04
31 INT130485 Gene_expression of SLC7A5 2 0.65 0 0.03
32 INT326371 Localization of SLC7A5 1 0.73 0 0.03
33 INT271833 Negative_regulation of Gene_expression of SLC7A7 3 0.57 0.2 0
34 INT205992 Regulation of Gene_expression of SLC7A7 3 0.44 0.81 0
35 INT205996 Binding of SLC7A7 2 0.13 0.82 0
36 INT329469 Negative_regulation of Positive_regulation of SLC7A7 2 0.36 0.59 0
37 INT344342 Binding of PDPN 1 0.31 0.74 0
38 INT344340 Negative_regulation of Gene_expression of PDPN 1 0.36 1.53 0
39 INT178964 Positive_regulation of Gene_expression of Slc7a2 1 0.10 0.66 0
40 INT344339 Positive_regulation of PDPN 1 0.39 0.98 0
41 INT344335 Regulation of PDPN 1 0.38 0.41 0
42 INT344343 Transcription of PDPN 1 0.60 0.54 0
43 INT344337 Regulation of Negative_regulation of PDPN 1 0.23 0.05 0
44 INT344334 Negative_regulation of PDPN 1 0.36 2.76 0
45 INT344333 Negative_regulation of Binding of PDPN 1 0.36 0.74 0
46 INT202389 Phosphorylation of Pdpn 1 0.61 0 0
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