GO:0015222

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Name serotonin transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0015222
Unique Molecular Interactions 102
Total Molecular Interactions 134
Total Single Events 1844
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for serotonin transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for serotonin transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
2 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
3 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
4 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
5 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
6 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
7 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
8 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
9 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
10 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
11 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
12 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
13 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
14 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
15 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
16 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
17 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
18 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
19 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
20 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
21 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
22 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
23 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
24 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
25 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
26 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
27 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
28 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
29 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
30 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
31 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
32 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
33 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
34 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
35 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
36 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
37 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
38 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
39 INT333304 Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.68 0.1 0.06
40 INT333297 Gtf3a Positive_regulation of Gene_expression of Slc6a4 1 0.01 0.1 0.06
41 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
42 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05
43 INT333301 Binding of Slc6a4 and Zic2 1 0.47 0 0.03
44 INT333307 Gene_expression of Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.45 0.05 0.03
45 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0
46 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0
47 INT127457 Ccl2 Positive_regulation of Gene_expression of Slc6a4 1 0.13 0 0
48 INT127464 Binding of PAH and Slc6a4 1 0.08 0 0
49 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0
50 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0
51 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0
52 INT333306 Ephb1 Regulation of Gene_expression of Slc6a4 1 0.19 0.21 0
53 INT333295 Gtf3a Positive_regulation of Slc6a4 1 0.01 0 0
54 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0
55 INT333300 Positive_regulation of Zic2 Positive_regulation of Slc6a4 1 0.45 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for serotonin transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in serotonin transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
3 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
4 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
5 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
6 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
7 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
8 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
9 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
10 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
11 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
12 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
13 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
14 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
15 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
16 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
17 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
18 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62
19 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
20 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
21 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
22 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
23 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
24 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
25 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
26 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
27 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
28 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
29 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
30 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
31 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
32 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
33 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
34 INT244284 Binding of SLC18A2 1 0.23 1.87 1.34
35 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
36 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
37 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
38 INT132574 Positive_regulation of SLC18A2 1 0.12 0.25 0.99
39 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
40 INT326601 Gene_expression of SLC18A2 2 0.42 1.31 0.92
41 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
42 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
43 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
44 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
45 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
46 INT326602 Negative_regulation of Gene_expression of SLC18A2 1 0.25 0.93 0.67
47 INT286687 Phosphorylation of Slc6a4 1 0.46 0 0.58
48 INT286690 Positive_regulation of Phosphorylation of Slc6a4 1 0.28 0 0.58
49 INT106568 Regulation of Regulation of Slc6a4 1 0.22 0.07 0.52
50 INT271164 Negative_regulation of Transcription of Slc6a4 1 0.04 0.47 0.52
51 INT129524 Regulation of Regulation of SLC6A4 1 0.26 0.16 0.5
52 INT352021 Negative_regulation of Negative_regulation of SLC6A4 1 0.08 0.2 0.5
53 INT150168 Negative_regulation of Transcription of SLC6A4 1 0.42 0.16 0.47
54 INT150167 Positive_regulation of Transcription of SLC6A4 1 0.45 0.16 0.46
55 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36
56 INT140668 Positive_regulation of Negative_regulation of SLC6A4 1 0.56 0.23 0.36
57 INT148455 Positive_regulation of Negative_regulation of Slc6a4 1 0.50 0.18 0.34
58 INT124930 Positive_regulation of Binding of SLC6A4 1 0.40 0.06 0.33
59 INT341784 Positive_regulation of Phosphorylation of SLC6A4 1 0.29 0.07 0.26
60 INT79350 Positive_regulation of Binding of Slc6a4 1 0.34 0 0.24
61 INT340198 Regulation of Transcription of Slc6a4 1 0.36 0.66 0.22
62 INT103022 Positive_regulation of Transcription of Slc6a4 2 0.44 0.52 0.21
63 INT332749 Positive_regulation of Binding of Slc6a4 1 0.23 0.19 0.07
64 INT333286 Negative_regulation of Positive_regulation of Slc6a4 1 0.50 0 0
65 INT333280 Regulation of Localization of Slc6a4 1 0.38 0.18 0
66 INT101927 Negative_regulation of Binding of Slc6a4 1 0.59 0 0
67 INT127454 Negative_regulation of Positive_regulation of Slc6a4 1 0.32 0 0
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