GO:0015250

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Name water channel activity
Categary Function
Go Slim No
Go Link GO:0015250
Unique Molecular Interactions 169
Total Molecular Interactions 230
Total Single Events 3690
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for water channel activity. They are ordered first by their pain relevance and then by number of times they were reported for water channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
2 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
3 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48
4 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
5 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
6 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
7 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
8 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92
9 INT334130 Negative_regulation of Acsm3 Positive_regulation of Mip 1 0.12 1.48 0.81
10 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
11 INT334134 Acsm3 Positive_regulation of Gene_expression of Mip 1 0.13 1.4 0.77
12 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75
13 INT199395 Mip Positive_regulation of Positive_regulation of Trpv1 1 0.01 0.86 0.69
14 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62
15 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
16 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55
17 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53
18 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
19 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
20 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
21 INT335996 Mmp8 Regulation of Protein_catabolism of MIP 1 0.44 1.06 0.43
22 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
23 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
24 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
25 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35
26 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
27 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32
28 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
29 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
30 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
31 INT109711 Mip Positive_regulation of Rtcd1 1 0.00 0 0.29
32 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
33 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26
34 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
35 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
36 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
37 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
38 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22
39 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2
40 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
41 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
42 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
43 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
44 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
45 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
46 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
47 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
48 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
49 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
50 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14
51 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
52 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09
53 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09
54 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09
55 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08
56 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
57 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
58 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
59 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05
60 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
61 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04
62 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
63 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04
64 INT293559 Binding of CALM1 and Aqp6 1 0.01 0 0.03
65 INT344317 PDPN Negative_regulation of VEGFA 1 0.08 0.67 0.03
66 INT344308 Positive_regulation of PDPN Negative_regulation of VEGFA 1 0.09 0.24 0.03
67 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
68 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
69 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
70 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0
71 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0
72 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0
73 INT347723 Binding of Aqp4 and Tmed4 1 0.27 0 0
74 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0
75 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0
76 INT327845 Binding of Aqp9 and Ooep 1 0.00 0 0
77 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0
78 INT308703 Positive_regulation of Binding of AQP4 and M1 1 0.08 0.61 0
79 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0
80 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
81 INT308707 Binding of AQP4 and IGHG3 1 0.01 0.88 0
82 INT344319 MAPK8 Positive_regulation of PDPN 1 0.35 0.5 0
83 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
84 INT354080 Avpr2 Positive_regulation of Localization of Aqp2 1 0.02 0.07 0
85 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
86 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0
87 INT147068 Binding of Aqp4 and Tg(CAG-EGFP)D4Nagy 1 0.06 0 0
88 INT147065 IgG Regulation of Gene_expression of Aqp4 1 0.37 0 0
89 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0
90 INT344307 PDPN Negative_regulation of Gene_expression of VEGFA 1 0.08 0.36 0
91 INT344318 PDPN Positive_regulation of Positive_regulation of RHOA 1 0.11 0.92 0
92 INT347722 Binding of Aqp4 and Nidds 1 0.31 0.32 0
93 INT198110 Ar Positive_regulation of Gene_expression of Aqp9 1 0.13 0 0
94 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0
95 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0
96 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0
97 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0
98 INT147066 Binding of Aqp4 and IgG 1 0.40 0 0
99 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0
100 INT344316 VEGFA Positive_regulation of PDPN 1 0.09 0.4 0
101 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0
102 INT147067 Binding of Aqp4 and Nqo1 1 0.04 0 0
103 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for water channel activity. They are ordered first by their pain relevance and then by number of times they were reported in water channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
2 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
3 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53
4 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
5 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
6 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
7 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38
8 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14
9 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07
10 INT157959 Binding of AQP4 32 0.48 43.44 7.44
11 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
12 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
13 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
14 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
15 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
16 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
17 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
18 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
19 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
20 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
21 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
22 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
23 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
24 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
25 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
26 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48
27 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
28 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
29 INT157960 Regulation of AQP4 11 0.48 21.36 3.06
30 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94
31 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92
32 INT169747 Localization of AQP4 17 0.75 16.64 2.79
33 INT82885 Gene_expression of Mip 7 0.65 7.89 2.76
34 INT86713 Positive_regulation of Mip 10 0.67 6.44 2.63
35 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
36 INT104563 Localization of Aqp4 10 0.73 7.82 2.54
37 INT262474 Gene_expression of Aqp6 26 0.77 2.08 2.49
38 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47
39 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
40 INT83294 Regulation of MIP 4 0.60 3.91 2.21
41 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
42 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
43 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
44 INT155344 Phosphorylation of Aqp4 1 0.82 4 2.05
45 INT83293 Negative_regulation of MIP 2 0.41 4.12 2.02
46 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99
47 INT140171 Binding of Aqp4 7 0.36 11.63 1.98
48 INT82886 Positive_regulation of Mip 7 0.49 3.61 1.89
49 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85
50 INT112971 Positive_regulation of Gene_expression of MIP 3 0.49 5.24 1.82
51 INT91336 Localization of MIP 5 0.78 2.97 1.79
52 INT83291 Regulation of Gene_expression of MIP 2 0.60 2 1.79
53 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
54 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68
55 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
56 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
57 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
58 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
59 INT45390 Negative_regulation of Mip 2 0.20 0.21 1.41
60 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
61 INT155345 Negative_regulation of Phosphorylation of Aqp4 1 0.43 2.86 1.37
62 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
63 INT152964 Regulation of Gene_expression of Aqp4 3 0.56 4.18 1.34
64 INT69863 Binding of Mip 7 0.36 4.54 1.33
65 INT32101 Regulation of Mip 3 0.26 0.89 1.31
66 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
67 INT289973 Negative_regulation of Gene_expression of MIP 2 0.41 2.69 1.15
68 INT79557 Localization of Aqp2 5 0.73 2 1.13
69 INT268763 Negative_regulation of Mip 3 0.41 2.61 1.12
70 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06
71 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02
72 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
73 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
74 INT101050 Localization of Mip 4 0.78 1.9 0.93
75 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
76 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
77 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
78 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77
79 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
80 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
81 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
82 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
83 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
84 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
85 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
86 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69
87 INT334126 Positive_regulation of Positive_regulation of Mip 1 0.20 1.65 0.67
88 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
89 INT327779 Regulation of Gene_expression of AQP4 5 0.48 4.5 0.6
90 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
91 INT91332 Regulation of Localization of MIP 1 0.44 0.75 0.6
92 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
93 INT100322 Localization of AQP2 5 0.80 0.56 0.56
94 INT210075 Positive_regulation of MIP 3 0.67 0.98 0.56
95 INT139780 Binding of AQP1 7 0.32 4.62 0.54
96 INT268755 Negative_regulation of Gene_expression of Mip 1 0.41 1.73 0.51
97 INT293553 Binding of Aqp6 2 0.36 0.31 0.46
98 INT19592 Localization of AQP1 4 0.81 1.09 0.44
99 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
100 INT183187 Transcription of Mip 2 0.69 0.69 0.43
101 INT335992 Protein_catabolism of MIP 1 0.86 1.04 0.42
102 INT293552 Negative_regulation of Gene_expression of Aqp6 1 0.58 0 0.4
103 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
104 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
105 INT268751 Positive_regulation of Binding of Mip 1 0.49 0.91 0.4
106 INT138976 Binding of Mip 3 0.30 0.17 0.39
107 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
108 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
109 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
110 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
111 INT299223 Negative_regulation of Transcription of Aqp4 3 0.59 1.36 0.35
112 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34
113 INT293558 Regulation of Gene_expression of Aqp6 1 0.27 0.16 0.34
114 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
115 INT293554 Localization of Aqp6 1 0.74 0.23 0.32
116 INT124634 Binding of MIP 2 0.35 0.46 0.31
117 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
118 INT247863 Positive_regulation of Negative_regulation of Aqp4 3 0.45 2.63 0.25
119 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25
120 INT318437 Negative_regulation of Pdpn 1 0.47 0.87 0.25
121 INT262487 Positive_regulation of Gene_expression of Aqp9 6 0.32 5.29 0.24
122 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24
123 INT327785 Transcription of AQP4 3 0.56 2.19 0.23
124 INT268762 Positive_regulation of Localization of Mip 1 0.49 0.83 0.23
125 INT283108 Regulation of Localization of Aqp4 1 0.41 0.44 0.23
126 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22
127 INT183186 Regulation of Mip 4 0.26 1.26 0.2
128 INT250270 Regulation of Localization of AQP4 1 0.41 0.22 0.2
129 INT268749 Regulation of Gene_expression of Mip 1 0.44 0.41 0.2
130 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
131 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18
132 INT268758 Regulation of Positive_regulation of Mip 1 0.44 0.83 0.18
133 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18
134 INT327780 Negative_regulation of Negative_regulation of AQP4 1 0.33 1.12 0.18
135 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
136 INT268756 Negative_regulation of Positive_regulation of Mip 1 0.41 0.83 0.17
137 INT250280 Positive_regulation of Negative_regulation of AQP4 1 0.37 0.58 0.17
138 INT285900 Positive_regulation of Localization of MIP 1 0.49 1.09 0.17
139 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
140 INT122708 Localization of Mip 2 0.61 0.17 0.16
141 INT160121 Localization of PDPN 1 0.73 1.07 0.16
142 INT262482 Positive_regulation of Gene_expression of Aqp6 3 0.46 0.14 0.14
143 INT215464 Positive_regulation of Transcription of Aqp5 1 0.45 0.42 0.13
144 INT215463 Regulation of Aqp5 1 0.44 0.42 0.13
145 INT215465 Transcription of Aqp5 1 0.52 0.42 0.13
146 INT250279 Positive_regulation of Localization of AQP4 1 0.46 0.69 0.13
147 INT332570 Phosphorylation of Aqp4 1 0.59 0.9 0.13
148 INT198121 Gene_expression of Aqp9 19 0.77 5.67 0.12
149 INT293557 Negative_regulation of Aqp6 1 0.58 0 0.12
150 INT327838 Negative_regulation of Aqp9 1 0.27 0.78 0.12
151 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11
152 INT101051 Regulation of Localization of Mip 1 0.19 0.09 0.11
153 INT327825 Positive_regulation of Binding of Aqp4 1 0.42 1.5 0.11
154 INT198124 Regulation of Aqp9 6 0.61 3.62 0.1
155 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
156 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
157 INT104565 Localization of Aqp3 1 0.46 1.21 0.1
158 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09
159 INT260915 Transcription of Aqp3 1 0.67 0.21 0.09
160 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
161 INT268748 Phosphorylation of Mip 1 0.79 0.08 0.08
162 INT327827 Negative_regulation of Gene_expression of Aqp1 1 0.45 0.8 0.08
163 INT289825 Positive_regulation of Aqp6 2 0.21 0.62 0.07
164 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
165 INT327778 Positive_regulation of Regulation of AQP4 1 0.37 2.84 0.07
166 INT327837 Negative_regulation of Aqp5 1 0.18 1.48 0.07
167 INT198119 Positive_regulation of Gene_expression of Aqp9 8 0.50 1.42 0.05
168 INT198114 Negative_regulation of Aqp9 2 0.42 1.4 0.05
169 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
170 INT262489 Positive_regulation of Aqp9 1 0.22 0.26 0.05
171 INT262485 Positive_regulation of Aqp5 1 0.28 0.36 0.04
172 INT293555 Positive_regulation of Localization of Aqp6 1 0.50 0 0.04
173 INT344332 Positive_regulation of Gene_expression of PDPN 1 0.58 0.72 0.04
174 INT293556 Regulation of Aqp6 1 0.23 0.05 0.04
175 INT327841 Localization of Aqp5 1 0.34 0.67 0.04
176 INT344330 Phosphorylation of PDPN 1 0.53 0.15 0.04
177 INT327832 Negative_regulation of Aqp3 1 0.17 0 0.04
178 INT293105 Positive_regulation of Positive_regulation of Aqp2 1 0.47 0.72 0.03
179 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03
180 INT235949 Regulation of Positive_regulation of Aqp4 1 0.37 0 0.03
181 INT198123 Regulation of Gene_expression of Aqp9 5 0.61 0.55 0
182 INT198122 Positive_regulation of Aqp9 4 0.69 0.84 0
183 INT280794 Localization of Aqp2 2 0.36 0.07 0
184 INT299199 Positive_regulation of Transcription of Aqp9 1 0.47 0 0
185 INT276270 Positive_regulation of Binding of MIP 1 0.16 0 0
186 INT273193 Negative_regulation of Gene_expression of Aqp3 1 0.15 0.2 0
187 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
188 INT344342 Binding of PDPN 1 0.31 0.74 0
189 INT202372 Positive_regulation of Transcription of Aqp4 1 0.28 0.07 0
190 INT157833 Negative_regulation of Negative_regulation of Aqp2 1 0.36 0 0
191 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0
192 INT280786 Phosphorylation of Aqp2 1 0.32 0.24 0
193 INT327783 Regulation of Transcription of AQP4 1 0.35 1.03 0
194 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
195 INT247864 Positive_regulation of Protein_catabolism of Aqp4 1 0.45 0.41 0
196 INT297668 Positive_regulation of Aqp2 1 0.45 0 0
197 INT108349 Regulation of AQP2 1 0.44 0 0
198 INT100325 Positive_regulation of AQP2 1 0.69 0 0
199 INT283116 Regulation of Negative_regulation of Aqp4 1 0.41 0.32 0
200 INT299204 Transcription of Mip 1 0.21 0.62 0
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