GO:0015269

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Name calcium-activated potassium channel activity
Categary Function
Go Slim No
Go Link GO:0015269
Unique Molecular Interactions 100
Total Molecular Interactions 213
Total Single Events 1070
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calcium-activated potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported for calcium-activated potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
2 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
3 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
4 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
5 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
6 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
7 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
8 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
9 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
10 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
11 INT54559 KCNMA1 Positive_regulation of Localization of TBXA2R 1 0.01 0.07 0.81
12 INT350344 Gene_expression of Kcnn2 Negative_regulation of Positive_regulation of Ltp 1 0.10 0 0.79
13 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
14 INT305405 Binding of KCNMA1 and ANTXR1 1 0.00 0.09 0.38
15 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3
16 INT165478 Prok2 Positive_regulation of Positive_regulation of Kcnma1 1 0.02 0 0.25
17 INT291448 Prkaca Regulation of Gene_expression of Kcnn2 1 0.04 0 0.23
18 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
19 INT127715 Q Negative_regulation of Kcnmb1 1 0.00 0.27 0.21
20 INT210990 Binding of KCNMA1 and PKDREJ 1 0.00 0.6 0.19
21 INT216487 Ca2 Negative_regulation of Kcnma1 1 0.00 0.1 0.17
22 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1
23 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1
24 INT153028 Binding of INSRR and KCNMA1 1 0.06 0.29 0.1
25 INT153027 Binding of HTR3A and KCNMA1 1 0.18 0.29 0.1
26 INT291450 Kcnn3 Negative_regulation of Gene_expression of SK 1 0.10 0.53 0.08
27 INT216570 Gene_expression of cx Positive_regulation of Kcnma1 1 0.00 0.25 0.06
28 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
29 INT288595 Binding of CYTIP and Kcnma1 1 0.00 0 0.04
30 INT323286 CYP4A11 Positive_regulation of Kcnma1 1 0.01 0.45 0.04
31 INT133482 CREB1 Positive_regulation of KCNMA1 1 0.01 0.43 0.03
32 INT133483 AKT1 Positive_regulation of KCNMA1 1 0.00 0.43 0.03
33 INT329993 Binding of CACNA1C and KCNMA1 1 0.32 0.19 0
34 INT100747 Kcnma1 Positive_regulation of sar 1 0.03 0 0
35 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
36 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
37 INT329990 Binding of KCNMA1 and SNRNP70 1 0.03 0.96 0
38 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
39 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
40 INT329995 Binding of KCNMA1 and AKAP6 1 0.40 0.48 0
41 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
42 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
43 INT179301 CA2 Regulation of KCNMA1 1 0.11 0 0
44 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
45 INT295293 Kcnn3 Regulation of Positive_regulation of Mapk14 1 0.11 0.12 0
46 INT338184 Binding of PCa and HPN 1 0.02 0.79 0
47 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
48 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0
49 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
50 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
51 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for calcium-activated potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported in calcium-activated potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
2 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
3 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55
4 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82
5 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
6 INT84162 Negative_regulation of KCNMA1 26 0.58 5.05 7.58
7 INT90777 Gene_expression of Kcnn3 39 0.77 10.35 6.35
8 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
9 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3
10 INT150144 Gene_expression of Kcnn3 31 0.78 7.67 4.24
11 INT187360 Gene_expression of Kcnn2 17 0.55 2.51 3.91
12 INT11490 Binding of KCNMA1 13 0.37 3.61 3.32
13 INT11485 Localization of KCNMA1 7 0.09 1.81 2.6
14 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56
15 INT11487 Positive_regulation of Localization of KCNMA1 4 0.06 1.5 2.31
16 INT64075 Positive_regulation of Positive_regulation of Kcnma1 2 0.02 0.55 1.96
17 INT157366 Positive_regulation of Positive_regulation of KCNMA1 2 0.05 2.43 1.74
18 INT150141 Positive_regulation of Gene_expression of Kcnn3 14 0.66 3.54 1.64
19 INT179309 Regulation of Gene_expression of KCNMA1 8 0.39 2.36 1.36
20 INT162361 Positive_regulation of Gene_expression of KCNMA1 6 0.46 2.44 1.25
21 INT162357 Protein_catabolism of KCNMA1 3 0.77 1.19 1.18
22 INT90775 Regulation of Kcnn3 3 0.35 3.31 1.04
23 INT72255 Binding of Kcnma1 4 0.02 0.2 0.99
24 INT150137 Transcription of Kcnn3 4 0.53 0.46 0.87
25 INT7457 Localization of Kcnma1 3 0.60 2.75 0.85
26 INT139928 Negative_regulation of Kcnma1 6 0.37 1.19 0.84
27 INT350317 Positive_regulation of Gene_expression of Kcnn2 1 0.23 0 0.78
28 INT69771 Positive_regulation of Kcnma1 6 0.52 0.31 0.74
29 INT150145 Regulation of Kcnn3 2 0.45 1.11 0.71
30 INT90776 Positive_regulation of Gene_expression of Kcnn3 4 0.69 0.92 0.7
31 INT215809 Gene_expression of Kcnma1 11 0.58 0.53 0.66
32 INT288019 Regulation of Gene_expression of Kcnma1 3 0.00 0.7 0.63
33 INT104095 Positive_regulation of Negative_regulation of KCNMA1 1 0.02 0 0.61
34 INT121195 Phosphorylation of KCNMA1 5 0.63 0.49 0.6
35 INT162362 Positive_regulation of Protein_catabolism of KCNMA1 1 0.05 0.61 0.6
36 INT101705 Negative_regulation of Positive_regulation of Kcnma1 2 0.03 0 0.59
37 INT162355 Regulation of Protein_catabolism of KCNMA1 1 0.05 0.59 0.59
38 INT150142 Negative_regulation of Kcnn3 5 0.59 2.82 0.58
39 INT291431 Negative_regulation of Gene_expression of Kcnn2 1 0.42 0.73 0.56
40 INT291438 Positive_regulation of Kcnn2 1 0.43 0.17 0.53
41 INT307752 Negative_regulation of Regulation of Kcnma1 1 0.01 0.18 0.52
42 INT187358 Localization of Kcnn3 2 0.72 1.65 0.51
43 INT309304 Regulation of Negative_regulation of KCNMA1 2 0.04 0.06 0.5
44 INT320019 Regulation of Positive_regulation of Kcnma1 1 0.01 0.05 0.49
45 INT150146 Positive_regulation of Kcnn3 6 0.66 0.92 0.46
46 INT90774 Negative_regulation of Kcnn3 2 0.45 2.57 0.42
47 INT90778 Regulation of Gene_expression of Kcnn3 2 0.61 1.56 0.37
48 INT123420 Negative_regulation of Gene_expression of KCNMA1 7 0.58 0.25 0.33
49 INT291428 Positive_regulation of Transcription of Kcnn3 1 0.45 0 0.31
50 INT99793 Regulation of Negative_regulation of Kcnma1 1 0.01 0.1 0.3
51 INT288561 Regulation of Kcnma1 5 0.21 0.49 0.26
52 INT291436 Phosphorylation of Kcnn2 1 0.58 0 0.22
53 INT187356 Binding of Kcnn3 1 0.25 1.17 0.19
54 INT295286 Positive_regulation of Kcnn3 1 0.53 0.35 0.17
55 INT72251 Phosphorylation of Kcnma1 2 0.05 0.07 0.13
56 INT295284 Transcription of Kcnn3 1 0.41 0.22 0.12
57 INT84161 Regulation of Positive_regulation of KCNMA1 2 0.27 0.25 0.11
58 INT295283 Localization of Kcnn3 1 0.62 0.21 0.09
59 INT183722 Gene_expression of HPN 3 0.37 1.63 0.08
60 INT295287 Negative_regulation of Gene_expression of Kcnn3 1 0.33 1.26 0.08
61 INT150139 Negative_regulation of Transcription of Kcnn3 1 0.43 0.3 0.06
62 INT179308 Regulation of Phosphorylation of KCNMA1 1 0.21 0 0.05
63 INT288560 Binding of Kcnma1 1 0.16 0.16 0.05
64 INT308287 Positive_regulation of HPN 1 0.39 0.48 0.05
65 INT288573 Regulation of Gene_expression of Kcnma1 1 0.21 0 0.04
66 INT179313 Regulation of Regulation of KCNMA1 1 0.34 0 0.04
67 INT179316 Regulation of Transcription of KCNMA1 1 0.39 0.05 0.03
68 INT179319 Transcription of KCNMA1 3 0.70 2.02 0
69 INT288559 Regulation of Positive_regulation of Kcnma1 1 0.21 0 0
70 INT288577 Regulation of Localization of Kcnma1 1 0.21 0 0
71 INT295281 Binding of Kcnn3 1 0.29 0.13 0
72 INT291430 Binding of Kcnn2 1 0.23 0 0
73 INT295289 Positive_regulation of Negative_regulation of Kcnn3 1 0.34 0 0
74 INT295285 Positive_regulation of Negative_regulation of Kcnma1 1 0.08 0 0
75 INT150143 Negative_regulation of Gene_expression of Kcnn3 1 0.59 0.23 0
76 INT291288 Binding of HPN 1 0.09 0.3 0
77 INT288568 Regulation of Regulation of Kcnma1 1 0.09 0 0
78 INT288567 Localization of Kcnma1 1 0.27 0 0
79 INT253798 Protein_catabolism of Kcnma1 1 0.57 0 0
80 INT288566 Negative_regulation of Binding of Kcnma1 1 0.15 0 0
81 INT179306 Negative_regulation of Transcription of KCNMA1 1 0.38 0 0
82 INT308286 Negative_regulation of HPN 1 0.36 0.19 0
83 INT202851 Positive_regulation of Negative_regulation of Kcnma1 1 0.01 0.38 0
84 INT286831 Positive_regulation of Positive_regulation of Kcnma1 1 0.38 0.08 0
85 INT150138 Regulation of Gene_expression of Kcnn3 1 0.54 1.96 0
86 INT292781 Positive_regulation of Positive_regulation of Kcnn3 1 0.01 0.49 0
87 INT207714 Positive_regulation of Gene_expression of HPN 1 0.33 0.57 0
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