GO:0015288

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Name porin activity
Categary Function
Go Slim No
Go Link GO:0015288
Unique Molecular Interactions 35
Total Molecular Interactions 42
Total Single Events 977
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for porin activity. They are ordered first by their pain relevance and then by number of times they were reported for porin activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
2 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
3 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
4 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
5 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
6 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
7 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
8 INT221258 Negative_regulation of Binding of VDAC1 and Crk 1 0.00 0.22 0.08
9 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08
10 INT221255 Binding of VDAC1 and Crk 1 0.00 0.22 0.08
11 INT267776 Binding of Vdac3 and IgG 1 0.01 0.69 0.08
12 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
13 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05
14 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04
15 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04
16 INT322667 Binding of Vdac1 and Pbrm1 1 0.15 0.79 0.03
17 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
18 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
19 INT215349 Binding of VDAC1 and Tspo 1 0.00 0.63 0
20 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0
21 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0
22 INT347723 Binding of Aqp4 and Tmed4 1 0.27 0 0
23 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0
24 INT327845 Binding of Aqp9 and Ooep 1 0.00 0 0
25 INT215344 Binding of Sp1 and Vdac1 1 0.02 0.1 0
26 INT354080 Avpr2 Positive_regulation of Localization of Aqp2 1 0.02 0.07 0
27 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0
28 INT147068 Binding of Aqp4 and Tg(CAG-EGFP)D4Nagy 1 0.06 0 0
29 INT147065 IgG Regulation of Gene_expression of Aqp4 1 0.37 0 0
30 INT347722 Binding of Aqp4 and Nidds 1 0.31 0.32 0
31 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0
32 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0
33 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0
34 INT147066 Binding of Aqp4 and IgG 1 0.40 0 0
35 INT147067 Binding of Aqp4 and Nqo1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for porin activity. They are ordered first by their pain relevance and then by number of times they were reported in porin activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
2 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
3 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
4 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
5 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
6 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
7 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
8 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
9 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
10 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
11 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
12 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
13 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
14 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48
15 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
16 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
17 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94
18 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92
19 INT104563 Localization of Aqp4 10 0.73 7.82 2.54
20 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
21 INT155344 Phosphorylation of Aqp4 1 0.82 4 2.05
22 INT140171 Binding of Aqp4 7 0.36 11.63 1.98
23 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
24 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
25 INT155345 Negative_regulation of Phosphorylation of Aqp4 1 0.43 2.86 1.37
26 INT152964 Regulation of Gene_expression of Aqp4 3 0.56 4.18 1.34
27 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02
28 INT114136 Binding of Vdac1 3 0.47 2.02 0.97
29 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
30 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
31 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
32 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
33 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69
34 INT221223 Phosphorylation of VDAC1 1 0.01 1.16 0.63
35 INT114138 Gene_expression of Vdac1 18 0.59 7.07 0.53
36 INT114139 Gene_expression of Vdac3 1 0.46 0 0.53
37 INT114143 Negative_regulation of Vdac3 2 0.39 0.85 0.47
38 INT299223 Negative_regulation of Transcription of Aqp4 3 0.59 1.36 0.35
39 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34
40 INT215348 Binding of VDAC1 1 0.01 1.43 0.33
41 INT215347 Regulation of VDAC1 1 0.01 0.13 0.27
42 INT215322 Positive_regulation of Vdac1 1 0.10 1.06 0.27
43 INT247863 Positive_regulation of Negative_regulation of Aqp4 3 0.45 2.63 0.25
44 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25
45 INT262487 Positive_regulation of Gene_expression of Aqp9 6 0.32 5.29 0.24
46 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24
47 INT283108 Regulation of Localization of Aqp4 1 0.41 0.44 0.23
48 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22
49 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18
50 INT332570 Phosphorylation of Aqp4 1 0.59 0.9 0.13
51 INT327838 Negative_regulation of Aqp9 1 0.27 0.78 0.12
52 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11
53 INT327825 Positive_regulation of Binding of Aqp4 1 0.42 1.5 0.11
54 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09
55 INT221222 Localization of VDAC1 1 0.01 0.25 0.09
56 INT232495 Gene_expression of VDAC1 1 0.06 0.64 0.06
57 INT262489 Positive_regulation of Aqp9 1 0.22 0.26 0.05
58 INT322643 Localization of Vdac1 1 0.33 0.91 0.03
59 INT322645 Positive_regulation of Localization of Vdac1 1 0.22 0.93 0.03
60 INT235949 Regulation of Positive_regulation of Aqp4 1 0.37 0 0.03
61 INT215327 Positive_regulation of Gene_expression of Vdac1 12 0.16 5.79 0
62 INT280794 Localization of Aqp2 2 0.36 0.07 0
63 INT202372 Positive_regulation of Transcription of Aqp4 1 0.28 0.07 0
64 INT215335 Regulation of Positive_regulation of Vdac1 1 0.07 0.17 0
65 INT280786 Phosphorylation of Aqp2 1 0.32 0.24 0
66 INT247864 Positive_regulation of Protein_catabolism of Aqp4 1 0.45 0.41 0
67 INT297668 Positive_regulation of Aqp2 1 0.45 0 0
68 INT215330 Positive_regulation of Transcription of Vdac1 1 0.07 0.28 0
69 INT283116 Regulation of Negative_regulation of Aqp4 1 0.41 0.32 0
70 INT221217 Negative_regulation of Vdac1 1 0.18 0.93 0
71 INT315124 Protein_catabolism of VDAC1 1 0.49 0.48 0
72 INT215320 Regulation of Vdac1 1 0.07 0.21 0
73 INT242407 Negative_regulation of Positive_regulation of Aqp4 1 0.09 0 0
74 INT215329 Transcription of Vdac1 1 0.10 0.28 0
75 INT247880 Protein_catabolism of Aqp4 1 0.64 1.35 0
76 INT215338 Regulation of Gene_expression of Vdac1 1 0.04 0.56 0
77 INT147064 Protein_catabolism of Aqp4 1 0.94 0 0
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