GO:0015297

From wiki-pain
Jump to: navigation, search
Name antiporter activity
Categary Function
Go Slim No
Go Link GO:0015297
Unique Molecular Interactions 40
Total Molecular Interactions 47
Total Single Events 344
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for antiporter activity. They are ordered first by their pain relevance and then by number of times they were reported for antiporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
2 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
3 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
4 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
5 INT240066 KCNIP3 Regulation of SLC8A3 1 0.39 0.73 0.59
6 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
7 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
8 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
9 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
10 INT103795 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of NFKB1 1 0.12 0.47 0.37
11 INT103386 Negative_regulation of SLC9A1 Negative_regulation of Gene_expression of IL8 1 0.02 0.97 0.36
12 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
13 INT103391 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of Nfkb1 1 0.01 0.88 0.32
14 INT103385 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of CDK20 1 0.02 0.88 0.32
15 INT103390 Negative_regulation of SLC9A1 Negative_regulation of Nfkb1 1 0.01 0.88 0.32
16 INT23810 Slc47a2 Positive_regulation of Positive_regulation of Itpka 1 0.05 0 0.29
17 INT334666 Slc9a1 Positive_regulation of Grin1 1 0.09 0.09 0.27
18 INT334667 Slc9a1 Positive_regulation of Ltp 1 0.13 0.09 0.27
19 INT353691 Slc8a1 Positive_regulation of Ca2 1 0.18 0.45 0.22
20 INT353697 Binding of NA and Slc8a1 1 0.01 0.42 0.19
21 INT298448 Binding of SLC4A1 and Slc4a3 1 0.39 1.89 0.15
22 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12
23 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12
24 INT236040 VIP Negative_regulation of SLC9A3 1 0.10 0 0.1
25 INT120152 Binding of PMEL and SLC9A7 1 0.07 0 0.09
26 INT120153 Binding of PMEL and SLC9A3 1 0.07 0 0.09
27 INT241040 Slc8a1 Negative_regulation of Gene_expression of Ca2 1 0.15 1.35 0.09
28 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09
29 INT137255 BCL2L11 Regulation of SLC4A3 1 0.10 0.99 0.08
30 INT253587 IFN1@ Negative_regulation of Gene_expression of Slc9a3 1 0.01 0 0.04
31 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03
32 INT297207 Myoz1 Regulation of Gene_expression of Slc8a1 1 0.09 0.26 0.03
33 INT236042 Negative_regulation of SLC9A3 Negative_regulation of SLC36A1 1 0.08 0.06 0
34 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0
35 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0
36 INT236044 Negative_regulation of SLC9A3 Negative_regulation of Gene_expression of SLC36A1 1 0.08 0.12 0
37 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0
38 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0
39 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for antiporter activity. They are ordered first by their pain relevance and then by number of times they were reported in antiporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
2 INT71974 Negative_regulation of SLC9A1 19 0.41 13.93 4.96
3 INT48994 Localization of Slc4a8 17 0.46 3.29 4.69
4 INT118518 Positive_regulation of Slc8a1 7 0.56 5.31 2.59
5 INT149125 Gene_expression of Slc4a3 25 0.78 3.45 2.41
6 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17
7 INT160634 Gene_expression of Slc8a1 2 0.64 2.12 1.92
8 INT25835 Binding of Slc8a1 3 0.36 0.47 1.79
9 INT73355 Negative_regulation of Slc8a1 5 0.47 2.35 1.61
10 INT283506 Gene_expression of SLC4A2 7 0.47 4 1.4
11 INT30201 Positive_regulation of Slc47a2 1 0.18 0 1.15
12 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02
13 INT188123 Gene_expression of Slc9a1 12 0.75 6.75 0.9
14 INT91666 Localization of SLC8A1 2 0.02 0.25 0.82
15 INT103800 Positive_regulation of SLC9A1 4 0.33 2.5 0.81
16 INT283501 Positive_regulation of Gene_expression of SLC4A2 1 0.19 1.66 0.73
17 INT283516 Localization of SLC4A2 1 0.21 0.8 0.69
18 INT152621 Regulation of SLC9A1 2 0.57 2.09 0.67
19 INT113088 Negative_regulation of SLC9A7 1 0.00 0.25 0.66
20 INT236053 Negative_regulation of SLC9A3 1 0.52 0.58 0.57
21 INT241034 Negative_regulation of Gene_expression of Slc8a1 4 0.34 2.23 0.48
22 INT71972 Positive_regulation of Negative_regulation of SLC9A1 1 0.19 0.35 0.48
23 INT283518 Negative_regulation of Gene_expression of SLC4A2 1 0.16 0.87 0.48
24 INT241035 Positive_regulation of Gene_expression of Slc8a1 4 0.41 1.89 0.47
25 INT120154 Gene_expression of SLC9A1 3 0.47 1.3 0.47
26 INT255002 Negative_regulation of Slc47a2 1 0.02 0.38 0.4
27 INT113859 Positive_regulation of SLC4A3 3 0.21 2.6 0.39
28 INT241036 Regulation of Slc8a1 5 0.22 3.43 0.37
29 INT99061 Negative_regulation of Negative_regulation of SLC9A1 1 0.30 0.3 0.37
30 INT353695 Regulation of Negative_regulation of Slc8a1 1 0.36 0.38 0.32
31 INT283504 Negative_regulation of Localization of SLC4A2 1 0.11 0.41 0.32
32 INT152623 Regulation of Regulation of SLC9A1 1 0.25 0.73 0.31
33 INT149126 Regulation of Gene_expression of Slc4a3 1 0.62 0.16 0.3
34 INT212132 Negative_regulation of Slc4a3 1 0.43 1.17 0.3
35 INT120711 Regulation of Localization of Slc4a8 1 0.16 0 0.29
36 INT120708 Positive_regulation of Localization of Slc4a8 1 0.40 0.27 0.29
37 INT69288 Negative_regulation of Localization of Slc4a8 1 0.03 0.14 0.24
38 INT43106 Binding of Slc47a2 1 0.24 0.07 0.24
39 INT212127 Positive_regulation of Gene_expression of Slc4a3 1 0.50 0.93 0.23
40 INT164753 Negative_regulation of Clcn5 2 0.58 5.13 0.2
41 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19
42 INT120161 Transcription of SLC9A1 1 0.27 0 0.19
43 INT119792 Negative_regulation of Localization of SLC8A1 1 0.01 0 0.18
44 INT212136 Positive_regulation of Slc4a3 1 0.70 0.54 0.17
45 INT195015 Negative_regulation of Positive_regulation of Slc8a1 1 0.04 0.31 0.15
46 INT212135 Localization of Slc4a3 2 0.73 0.35 0.13
47 INT212129 Transcription of Slc4a3 1 0.69 0.07 0.13
48 INT170621 Binding of SLC9A1 1 0.25 0.69 0.12
49 INT95691 Negative_regulation of SLC4A3 1 0.18 0.92 0.12
50 INT221196 Positive_regulation of Slc9a1 2 0.67 1.12 0.11
51 INT236060 Regulation of SLC9A3 1 0.55 0.18 0.1
52 INT170622 Negative_regulation of Gene_expression of SLC9A1 1 0.26 0.38 0.1
53 INT120162 Gene_expression of SLC9A3 2 0.60 0.07 0.09
54 INT120157 Localization of SLC9A7 1 0.37 0 0.09
55 INT120163 Transcription of SLC9A3 1 0.36 0 0.09
56 INT120160 Localization of SLC9A3 1 0.36 0 0.09
57 INT120156 Gene_expression of SLC9A7 1 0.32 0 0.09
58 INT266031 Positive_regulation of Gene_expression of Slc9a1 1 0.29 0.69 0.08
59 INT188168 Binding of Slc4a3 4 0.47 1.06 0.07
60 INT160627 Positive_regulation of Slc8a1 2 0.22 0.27 0.07
61 INT156738 Binding of SLC4A3 1 0.36 0.83 0.07
62 INT164801 Localization of Slc47a2 1 0.00 0 0.07
63 INT236066 Positive_regulation of SLC9A3 1 0.62 0 0.05
64 INT253549 Gene_expression of Slc9a3 1 0.02 0 0.04
65 INT188119 Binding of Slc9a1 1 0.36 0.88 0.04
66 INT188126 Negative_regulation of Slc9a1 1 0.42 0.85 0.04
67 INT214002 Localization of Slc8a1 1 0.34 1.07 0.04
68 INT236055 Regulation of Negative_regulation of SLC9A3 1 0.40 0 0.03
69 INT297201 Regulation of Gene_expression of Slc8a1 1 0.22 0.2 0.03
70 INT296910 Regulation of Gene_expression of Slc8a1 1 0.18 0.68 0
71 INT323058 Negative_regulation of SLC8A1 1 0.07 1.57 0
72 INT183548 Localization of SLC9A1 1 0.01 0.24 0
73 INT340360 Positive_regulation of Clcn5 1 0.50 1.62 0
74 INT340365 Protein_catabolism of Clcn5 1 0.99 1.03 0
75 INT264147 Gene_expression of CLCN7 1 0.35 0.73 0
76 INT236052 Binding of SLC9A3 1 0.33 0 0
77 INT340363 Regulation of Clcn5 1 0.45 0.85 0
78 INT118100 Protein_catabolism of Slc8a1 1 0.33 0 0
79 INT212134 Regulation of Slc4a3 1 0.62 0.34 0
80 INT236064 Negative_regulation of Negative_regulation of SLC9A3 1 0.38 0 0
81 INT188128 Negative_regulation of Gene_expression of Slc9a1 1 0.41 0.08 0
82 INT340359 Binding of Clcn5 1 0.48 1.91 0
83 INT236063 Negative_regulation of Gene_expression of SLC9A3 1 0.38 0 0
84 INT340372 Negative_regulation of Protein_catabolism of Clcn5 1 0.43 1.07 0
85 INT340361 Binding of Clcn4-2 1 0.30 0.82 0
86 INT296919 Transcription of Slc8a1 1 0.24 1.28 0
87 INT296908 Regulation of Regulation of Slc8a1 1 0.12 0.61 0
88 INT297188 Negative_regulation of Slc8a1 1 0.31 0.31 0
89 INT283497 Negative_regulation of SLC4A2 1 0.14 0.95 0
90 INT340366 Gene_expression of Clcn5 1 0.77 4.8 0
91 INT296918 Positive_regulation of Transcription of Slc8a1 1 0.21 1.29 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox