GO:0015379

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Name potassium:chloride symporter activity
Categary Function
Go Slim No
Go Link GO:0015379
Unique Molecular Interactions 38
Total Molecular Interactions 46
Total Single Events 639
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for potassium:chloride symporter activity. They are ordered first by their pain relevance and then by number of times they were reported for potassium:chloride symporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
2 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
3 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23
4 INT169096 Hpcl1 Regulation of Gene_expression of Slc12a5 1 0.02 0.05 0.95
5 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
6 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
7 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
8 INT139131 Negative_regulation of Ltp Negative_regulation of Slc12a5 1 0.17 0.15 0.7
9 INT139132 Ltp Negative_regulation of Slc12a5 1 0.17 0.15 0.69
10 INT139133 Slc12a5 Negative_regulation of Gene_expression of Ltp 1 0.20 0.11 0.59
11 INT125492 D2Mit212 Negative_regulation of Slc12a7 1 0.00 0 0.54
12 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44
13 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
14 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38
15 INT261784 Positive_regulation of Bdnf Positive_regulation of Slc12a5 1 0.15 0.77 0.2
16 INT239790 SLC12A5 Regulation of SLC12A2 1 0.11 0.08 0.13
17 INT244338 Slc12a7 Positive_regulation of SERPINH1 1 0.00 0.26 0.13
18 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
19 INT114932 Slc12a6 Positive_regulation of Phosphorylation of Creb1 1 0.00 0 0.08
20 INT350257 Slc12a6 Negative_regulation of Pnlip 1 0.03 1.53 0.03
21 INT350256 Slc12a6 Negative_regulation of Positive_regulation of Fabp4 1 0.03 0.56 0
22 INT350254 Slc12a6 Regulation of Gene_expression of Adipoq 1 0.02 0.63 0
23 INT350255 Slc12a6 Negative_regulation of Transcription of Fabp4 1 0.03 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for potassium:chloride symporter activity. They are ordered first by their pain relevance and then by number of times they were reported in potassium:chloride symporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103172 Gene_expression of Slc12a5 81 0.77 39.45 36.22
2 INT103169 Negative_regulation of Slc12a5 38 0.58 27.75 20.81
3 INT103170 Negative_regulation of Gene_expression of Slc12a5 26 0.58 17.25 14.4
4 INT138890 Regulation of Slc12a5 12 0.45 11.61 7.46
5 INT103171 Positive_regulation of Slc12a5 15 0.51 3.6 6.25
6 INT165011 Gene_expression of SLC12A5 11 0.77 4.08 4.95
7 INT121252 Regulation of Gene_expression of Slc12a5 10 0.61 6.47 4.87
8 INT126099 Gene_expression of Slc12a5 9 0.77 5.72 4.36
9 INT139130 Positive_regulation of Gene_expression of Slc12a5 8 0.51 4.43 4.33
10 INT139129 Negative_regulation of Negative_regulation of Slc12a5 4 0.43 5.53 4.29
11 INT24377 Localization of Slc12a7 5 0.06 0 4.26
12 INT165013 Negative_regulation of Gene_expression of SLC12A5 3 0.58 3.55 4.22
13 INT203314 Negative_regulation of Gene_expression of Slc12a5 3 0.31 4.74 4.03
14 INT11445 Positive_regulation of Slc12a6 11 0.31 3.29 3.6
15 INT24857 Localization of Slc12a6 10 0.67 0.7 3.44
16 INT165590 Negative_regulation of Slc12a5 5 0.43 2.62 2.96
17 INT110333 Positive_regulation of Negative_regulation of Slc12a5 4 0.50 3.18 2.77
18 INT24376 Negative_regulation of Localization of Slc12a7 3 0.02 0 2.67
19 INT244384 Binding of Slc12a5 2 0.46 2.47 1.71
20 INT23290 Negative_regulation of Slc12a6 5 0.05 1.4 1.46
21 INT326191 Localization of Slc12a5 1 0.14 0.85 1.32
22 INT121251 Transcription of Slc12a5 2 0.66 1.72 1.27
23 INT110332 Gene_expression of Slc12a6 4 0.69 2.48 1.22
24 INT247922 Phosphorylation of Slc12a5 3 0.79 2.42 1.11
25 INT24856 Negative_regulation of Localization of Slc12a6 1 0.24 0 0.86
26 INT160020 Transcription of Slc12a5 2 0.53 0.75 0.83
27 INT59767 Positive_regulation of Positive_regulation of Slc12a6 1 0.00 0.06 0.69
28 INT247920 Positive_regulation of Phosphorylation of Slc12a5 2 0.51 0.9 0.63
29 INT203328 Positive_regulation of Gene_expression of Slc12a5 2 0.50 1.56 0.63
30 INT261776 Positive_regulation of Positive_regulation of Slc12a5 1 0.37 0 0.61
31 INT165012 Negative_regulation of SLC12A5 1 0.43 0.37 0.59
32 INT165014 Regulation of SLC12A5 1 0.45 0.37 0.59
33 INT261771 Negative_regulation of Positive_regulation of Slc12a5 1 0.32 0 0.56
34 INT125490 Regulation of Negative_regulation of Slc12a7 1 0.00 0 0.56
35 INT247919 Regulation of Phosphorylation of Slc12a5 1 0.59 1.54 0.54
36 INT125491 Negative_regulation of Slc12a7 1 0.00 0 0.54
37 INT247921 Negative_regulation of Phosphorylation of Slc12a5 1 0.56 1.58 0.49
38 INT165591 Negative_regulation of Negative_regulation of Slc12a5 1 0.43 0.35 0.49
39 INT243938 Regulation of Phosphorylation of Slc12a5 1 0.18 1.1 0.48
40 INT243918 Phosphorylation of Slc12a5 1 0.25 1.1 0.48
41 INT243914 Positive_regulation of Slc12a5 1 0.14 0 0.47
42 INT38022 Gene_expression of Slc12a7 3 0.17 2.78 0.41
43 INT239795 Localization of SLC12A5 1 0.33 0.14 0.28
44 INT243985 Regulation of Slc12a5 1 0.13 0.55 0.24
45 INT203305 Regulation of Gene_expression of Slc12a5 1 0.32 0.8 0.22
46 INT244390 Negative_regulation of Transcription of Slc12a5 1 0.54 0.4 0.2
47 INT246699 Positive_regulation of Gene_expression of Slc12a7 1 0.13 2.05 0.12
48 INT246704 Positive_regulation of Slc12a7 1 0.13 2.05 0.12
49 INT261781 Regulation of Positive_regulation of Slc12a5 1 0.20 0.08 0.09
50 INT110148 Regulation of Slc12a6 1 0.00 0 0
51 INT125263 Regulation of Localization of Slc12a6 1 0.18 0 0
52 INT125264 Positive_regulation of Localization of Slc12a6 1 0.30 0 0
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