GO:0015630

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Name microtubule cytoskeleton
Categary Component
Go Slim No
Go Link GO:0015630
Unique Molecular Interactions 817
Total Molecular Interactions 1103
Total Single Events 7222
Pain Genes Associated 52

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microtubule cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported for microtubule cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
3 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
4 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
5 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
6 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
7 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
8 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
9 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
10 INT128778 Binding of Mcam and Nav1 1 0.03 0.51 2.28
11 INT128777 Binding of Cntn1 and Nav1 1 0.48 0.51 2.28
12 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
13 INT6320 Binding of Rbm39 and Scq1 1 0.03 0 1.92
14 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
15 INT104710 Em Positive_regulation of Rbm39 1 0.02 0.07 1.76
16 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
17 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
18 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
19 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
20 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
21 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
22 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
23 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
24 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
25 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4
26 INT68071 Binding of Tic1 and Rbm39 1 0.01 2.54 1.33
27 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33
28 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32
29 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
30 INT85742 Pdyn Positive_regulation of Rbm39 1 0.01 0.17 1.29
31 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
32 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
33 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
34 INT85744 Binding of Pdyn and Rbm39 1 0.01 0.16 1.12
35 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
36 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
37 INT134870 Regulation of Binding of Calm3 and Nav1 1 0.17 0.42 1.1
38 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
39 INT134869 Binding of Calm3 and Nav1 1 0.31 0.42 1.1
40 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
41 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04
42 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
43 INT197241 Kars Regulation of Localization of Gabrg1 1 0.23 0 1.02
44 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01
45 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
46 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
47 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
48 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
49 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
50 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
51 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
52 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
53 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
54 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
55 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
56 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
57 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
58 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
59 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
60 INT151961 Rbm39 Positive_regulation of Insrr 1 0.17 0.26 0.89
61 INT59482 Cpe Positive_regulation of Rbm39 1 0.02 0 0.89
62 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88
63 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
64 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
65 INT139594 Binding of Nts and Rbm39 1 0.02 0.19 0.87
66 INT353719 Rbm39 Regulation of Localization of Vta1 1 0.01 0 0.84
67 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
68 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
69 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
70 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
71 INT139593 Ntsr1 Positive_regulation of Rbm39 1 0.01 0.17 0.79
72 INT296299 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Rbm39 1 0.00 0.59 0.79
73 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78
74 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
75 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
76 INT353718 Binding of Rbm39 and Ghsr 1 0.01 0 0.76
77 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
78 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74
79 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
80 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
81 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
82 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
83 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
84 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
85 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
86 INT353722 Rbm39 Positive_regulation of Localization of Ghrl 1 0.01 0 0.65
87 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
88 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
89 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
90 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
91 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
92 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
93 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
94 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
95 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
96 INT29803 Binding of Rtcd1 and Rbm39 1 0.00 0.14 0.59
97 INT56700 Penk Regulation of FER 1 0.00 0 0.59
98 INT352284 Dmbx1 Regulation of Nav1 1 0.26 0 0.59
99 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
100 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
101 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
102 INT145617 Ngf Positive_regulation of Gene_expression of Fez1 1 0.43 0.57 0.57
103 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
104 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57
105 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
106 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
107 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
108 INT253835 Binding of DST and Fos 1 0.02 0 0.55
109 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
110 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
111 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
112 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
113 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
114 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
115 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
116 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
117 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
118 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
119 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
120 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
121 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
122 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
123 INT14200 GNRH1 Positive_regulation of Localization of Azi1 1 0.00 0 0.49
124 INT313635 MUC7 Negative_regulation of Rbm39 1 0.00 0 0.48
125 INT296471 Camk2a Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
126 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
127 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
128 INT81036 Binding of Oprl1 and Rbm39 1 0.02 0.13 0.47
129 INT296487 PRKG1 Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
130 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
131 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
132 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
133 INT296451 Prkaca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
134 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
135 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
136 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
137 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
138 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46
139 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45
140 INT13364 Binding of Oprd1 and Rbm39 1 0.00 0 0.45
141 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
142 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
143 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
144 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
145 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
146 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
147 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
148 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
149 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
150 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
151 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
152 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
153 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
154 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
155 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
156 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
157 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
158 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
159 INT287751 Rbm39 Positive_regulation of Positive_regulation of Lpar1 1 0.01 0.48 0.39
160 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39
161 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
162 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
163 INT287745 Rbm39 Positive_regulation of Gene_expression of Lpar1 1 0.01 0.48 0.39
164 INT168200 Binding of CA1 and Nav1 1 0.11 0 0.39
165 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38
166 INT306694 Nav1 Positive_regulation of Gene_expression of Scn7a 1 0.01 0.07 0.38
167 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38
168 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38
169 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
170 INT56867 Binding of Rbm39 and Gm9007 1 0.00 0 0.37
171 INT56868 Binding of Rbm39 and Nle1 1 0.00 0 0.37
172 INT296476 Binding of Pick1 and Rbm39 1 0.00 0.57 0.37
173 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
174 INT56866 Binding of Cck and Rbm39 1 0.02 0 0.37
175 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
176 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
177 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
178 INT296444 Binding of Rbm39 and Myo18a 1 0.00 0.56 0.36
179 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
180 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
181 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
182 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
183 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
184 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
185 INT306692 Prkaca Regulation of Positive_regulation of Nav1 1 0.13 0.06 0.35
186 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35
187 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
188 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
189 INT296465 Binding of Dlg4 and Rbm39 1 0.00 0.05 0.34
190 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34
191 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
192 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
193 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
194 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
195 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
196 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
197 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
198 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
199 INT102974 Binding of ADRBK2 and Rbm39 1 0.00 0 0.31
200 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported for microtubule cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported in microtubule cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46
2 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28
3 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44
4 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
5 INT5770 Binding of Rbm39 88 0.41 13.23 55.5
6 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
7 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
8 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
9 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27
10 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27
11 INT116321 Regulation of Nav1 38 0.62 26.62 37.97
12 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28
13 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74
14 INT103262 Localization of Nav1 53 0.81 19.23 34.44
15 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
16 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27
17 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
18 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
19 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
20 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
21 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
22 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
23 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
24 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06
25 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15
26 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
27 INT112207 Binding of Nav1 27 0.47 7.1 15.43
28 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
29 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
30 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
31 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
32 INT5791 Positive_regulation of Positive_regulation of Rbm39 13 0.25 1.61 9.88
33 INT29802 Localization of Rbm39 18 0.64 4.04 9.84
34 INT102964 Phosphorylation of Rbm39 23 0.04 5.58 9.83
35 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
36 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
37 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
38 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
39 INT86792 Gene_expression of Kars 17 0.77 4.24 8.58
40 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
41 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
42 INT2802 Negative_regulation of Asrgl1 14 0.59 2.69 7.37
43 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
44 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
45 INT113376 Transcription of Nav1 7 0.69 0.93 6.36
46 INT111049 Negative_regulation of Positive_regulation of Nav1 5 0.43 4.39 6.25
47 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
48 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
49 INT178604 Gene_expression of TPX2 13 0.37 20.29 6.04
50 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6
51 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14
52 INT14018 Negative_regulation of Binding of Rbm39 6 0.31 1.84 4.93
53 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
54 INT197229 Positive_regulation of Kars 5 0.54 1.89 4.81
55 INT134657 Localization of Akt1 37 0.68 11.58 4.62
56 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
57 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
58 INT75136 Binding of Akt1 27 0.27 8.81 4.15
59 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
60 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
61 INT86769 Positive_regulation of Gene_expression of Rbm39 11 0.25 5.6 3.8
62 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
63 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
64 INT136692 Localization of Akt1 12 0.78 2.14 3.65
65 INT14319 Localization of SHMT2 3 0.03 1.91 3.61
66 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
67 INT132941 Positive_regulation of Phosphorylation of Rbm39 6 0.03 1.76 3.56
68 INT111053 Positive_regulation of Positive_regulation of Nav1 4 0.46 2.97 3.53
69 INT102076 Regulation of DST 15 0.22 10 3.5
70 INT42849 Regulation of Binding of Rbm39 1 0.37 0 3.29
71 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
72 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
73 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
74 INT197220 Positive_regulation of Gene_expression of Kars 3 0.39 0.29 3.15
75 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
76 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03
77 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
78 INT220335 Gene_expression of UROD 34 0.54 24.53 2.89
79 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
80 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
81 INT19985 Negative_regulation of Negative_regulation of Rbm39 4 0.16 0.99 2.79
82 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
83 INT113385 Negative_regulation of Transcription of Nav1 2 0.43 0.73 2.74
84 INT178606 Positive_regulation of Gene_expression of TPX2 4 0.08 8.73 2.71
85 INT69529 Positive_regulation of Localization of Rbm39 3 0.08 0.78 2.61
86 INT214355 Binding of Akt1 13 0.36 3.72 2.59
87 INT113375 Positive_regulation of Negative_regulation of Nav1 4 0.50 0.67 2.56
88 INT197225 Regulation of Positive_regulation of Kars 1 0.35 0 2.56
89 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49
90 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
91 INT342684 Phosphorylation of Nav1 2 0.68 0.23 2.37
92 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
93 INT118791 Binding of AKT1 32 0.48 15.51 2.25
94 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
95 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
96 INT106307 Positive_regulation of UROD 27 0.49 16.63 2.19
97 INT122890 Regulation of Gene_expression of Rbm39 5 0.13 1.96 2.17
98 INT112868 Gene_expression of Pcna 21 0.75 8.6 2.15
99 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
100 INT46849 Regulation of TPX2 5 0.24 6.27 2.1
101 INT54433 Transcription of Sptan1 1 0.69 0 2.03
102 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
103 INT68952 Localization of PCNA 17 0.62 5.64 1.78
104 INT73066 Positive_regulation of Binding of Rbm39 2 0.50 0.56 1.77
105 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
106 INT52758 Negative_regulation of Positive_regulation of Sptan1 2 0.57 0.33 1.73
107 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
108 INT240060 Binding of NME8 1 0.42 3.85 1.69
109 INT91043 Regulation of NDRG1 7 0.25 2.66 1.65
110 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
111 INT296262 Regulation of Phosphorylation of Rbm39 1 0.01 0.84 1.59
112 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56
113 INT44493 Regulation of SHMT2 3 0.29 0.45 1.55
114 INT46851 Negative_regulation of TPX2 3 0.38 1.68 1.54
115 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
116 INT113377 Positive_regulation of Localization of Nav1 2 0.70 0.23 1.46
117 INT168682 Localization of NDRG1 3 0.36 0.84 1.45
118 INT168684 Regulation of Localization of NDRG1 1 0.10 0.61 1.4
119 INT46848 Positive_regulation of TPX2 9 0.70 5.01 1.35
120 INT19619 Positive_regulation of SHMT2 6 0.08 1.05 1.35
121 INT134866 Negative_regulation of Binding of Nav1 1 0.42 0.38 1.33
122 INT116262 Gene_expression of Mycbp2 6 0.76 1.72 1.32
123 INT332311 Negative_regulation of Phosphorylation of Rbm39 5 0.01 1.16 1.29
124 INT38645 Negative_regulation of Positive_regulation of DST 3 0.29 1.05 1.29
125 INT116320 Regulation of Positive_regulation of Nav1 2 0.19 0.19 1.29
126 INT122892 Transcription of Rbm39 1 0.02 0.71 1.25
127 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
128 INT135556 Localization of AKT1 38 0.69 12.78 1.17
129 INT101027 Binding of DST 20 0.41 10.9 1.17
130 INT50389 Localization of Sptan1 3 0.73 0 1.16
131 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
132 INT22480 Binding of SHMT2 5 0.19 2.31 1.14
133 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
134 INT131373 Positive_regulation of NDRG1 9 0.67 4.78 1.11
135 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
136 INT80736 Protein_catabolism of Sptan1 5 0.32 3.32 1.1
137 INT296809 Negative_regulation of Negative_regulation of Nav1 4 0.38 1.33 1.1
138 INT81418 Positive_regulation of Localization of SHMT2 1 0.02 0.75 1.06
139 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
140 INT71987 Regulation of Gene_expression of Sptan1 1 0.60 0 1.03
141 INT262366 Localization of Adh4 1 0.78 1.88 1
142 INT175280 Binding of DBT 19 0.08 6.37 0.98
143 INT122073 Regulation of Regulation of Nav1 2 0.44 0.75 0.96
144 INT159986 Positive_regulation of Gene_expression of Sptan1 2 0.68 1.1 0.95
145 INT106746 Gene_expression of Mtap7 1 0.39 2.09 0.95
146 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
147 INT38557 Positive_regulation of Gene_expression of DBT 8 0.37 2.05 0.92
148 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
149 INT41307 Localization of Asrgl1 2 0.79 0.19 0.92
150 INT60553 Localization of TPX2 2 0.61 3.02 0.92
151 INT312277 Binding of TPX2 3 0.08 0.76 0.91
152 INT7702 Gene_expression of Asrgl1 5 0.77 3.33 0.89
153 INT197223 Localization of Kars 3 0.58 0.73 0.89
154 INT41306 Positive_regulation of Negative_regulation of Asrgl1 1 0.48 0 0.88
155 INT197221 Negative_regulation of Kars 2 0.33 0.69 0.87
156 INT38558 Positive_regulation of DBT 9 0.31 1.59 0.86
157 INT111485 Gene_expression of Pcna 2 0.75 0 0.83
158 INT284844 Regulation of Localization of Nav1 2 0.59 0.18 0.83
159 INT221543 Binding of Fes 1 0.45 1.79 0.83
160 INT187709 Regulation of Gene_expression of DBT 3 0.04 0.63 0.8
161 INT231650 Gene_expression of NUCB1 1 0.71 0.97 0.79
162 INT197211 Binding of Kars 2 0.29 1.3 0.78
163 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
164 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
165 INT116267 Binding of Mycbp2 1 0.35 0.37 0.71
166 INT220338 Positive_regulation of Gene_expression of UROD 2 0.49 3.55 0.69
167 INT257803 Regulation of Regulation of Rbm39 2 0.01 0.38 0.69
168 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
169 INT84830 Positive_regulation of Negative_regulation of Rbm39 1 0.02 0 0.68
170 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
171 INT187712 Negative_regulation of DBT 11 0.19 2.99 0.65
172 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
173 INT80737 Positive_regulation of Protein_catabolism of Sptan1 1 0.12 1.39 0.64
174 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
175 INT21663 Regulation of Negative_regulation of Asrgl1 1 0.03 0.21 0.6
176 INT244420 Positive_regulation of Gene_expression of DST 4 0.41 2.05 0.59
177 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
178 INT159968 Positive_regulation of Tbca 2 0.04 0.61 0.58
179 INT116319 Positive_regulation of Regulation of Nav1 2 0.19 0.09 0.57
180 INT159292 Regulation of Regulation of Azi1 1 0.01 0 0.56
181 INT169957 Transcription of PCNA 7 0.34 0.94 0.55
182 INT142419 Regulation of Sptan1 2 0.38 2.52 0.55
183 INT41305 Transcription of Asrgl1 1 0.66 0 0.55
184 INT111484 Positive_regulation of Gene_expression of Pcna 1 0.67 0 0.54
185 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
186 INT114071 Negative_regulation of Positive_regulation of Rbm39 2 0.10 0.71 0.53
187 INT159291 Regulation of Azi1 1 0.01 0 0.53
188 INT220333 Binding of UROD 4 0.30 2.66 0.52
189 INT176264 Binding of PCNA 21 0.21 9.08 0.51
190 INT116263 Regulation of Gene_expression of Mycbp2 1 0.60 0.58 0.5
191 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
192 INT14194 Localization of Azi1 1 0.01 0 0.49
193 INT241674 Negative_regulation of Transcription of PCNA 1 0.11 0.33 0.47
194 INT84831 Regulation of Positive_regulation of Rbm39 1 0.02 0.53 0.47
195 INT312528 Binding of Spib 1 0.00 1.46 0.46
196 INT115753 Regulation of Negative_regulation of Nav1 3 0.38 0 0.44
197 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43
198 INT197212 Regulation of Kars 1 0.35 0.1 0.43
199 INT45012 Negative_regulation of Azi1 1 0.37 0.18 0.43
200 INT214136 Localization of DST 7 0.65 2.59 0.42
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