GO:0015813

From wiki-pain
Jump to: navigation, search
Name L-glutamate transport
Categary Process
Go Slim No
Go Link GO:0015813
Unique Molecular Interactions 141
Total Molecular Interactions 186
Total Single Events 3080
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-glutamate transport. They are ordered first by their pain relevance and then by number of times they were reported for L-glutamate transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
2 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
3 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
4 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
5 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
6 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
7 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
8 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
9 INT74829 Oprd1 Regulation of Slc1a2 1 0.17 0 0.76
10 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
11 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
12 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
13 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
14 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
15 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
16 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
17 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
18 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
19 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4
20 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
21 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
22 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35
23 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
24 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34
25 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
26 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
27 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
28 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
29 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
30 INT305504 Slc17a6 Positive_regulation of Ex 1 0.05 0.67 0.22
31 INT305505 Negative_regulation of Binding of Igfals and Slc17a6 1 0.16 1.12 0.21
32 INT305510 Binding of Igfals and Slc17a6 1 0.14 1.11 0.21
33 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
34 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
35 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
36 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
37 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
38 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
39 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
40 INT305506 Binding of Pgk1 and Slc17a6 1 0.04 0.31 0.11
41 INT251231 Binding of Syp and Slc17a6 1 0.04 0 0.08
42 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
43 INT305503 Binding of Nr5a1 and Slc17a6 1 0.08 0.37 0.08
44 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
45 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
46 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
47 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
48 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
49 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
50 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
51 INT250243 FCGR3A Regulation of Gene_expression of SLC1A2 1 0.00 0.78 0.06
52 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05
53 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
54 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
55 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
56 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
57 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
58 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
59 INT314395 Binding of Gpsm2 and Slc17a6 1 0.20 0 0
60 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
61 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
62 INT326809 Binding of Ankrd36 and SLC25A22 1 0.10 0.13 0
63 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
64 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
65 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
66 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0
67 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
68 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
69 INT314399 Binding of Slc17a7 and Slc17a6 1 0.14 0 0
70 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
71 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
72 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
73 INT314396 Binding of Ptpn6 and Slc17a6 1 0.05 0 0
74 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
75 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
76 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
77 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
78 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-glutamate transport. They are ordered first by their pain relevance and then by number of times they were reported in L-glutamate transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
2 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
3 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
4 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
5 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
6 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57
7 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
8 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
9 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
10 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
11 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64
12 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
13 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
14 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
15 INT105194 Negative_regulation of Slc1a1 11 0.56 3.05 14.19
16 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
17 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
18 INT139935 Gene_expression of Slc17a6 36 0.78 8.43 10.61
19 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
20 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89
21 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
22 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
23 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
24 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
25 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14
26 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
27 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
28 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
29 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
30 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
31 INT139933 Negative_regulation of Slc17a6 3 0.59 10.25 5.43
32 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
33 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
34 INT124920 Positive_regulation of Negative_regulation of Slc1a2 4 0.58 0.06 4.69
35 INT132237 Negative_regulation of Gene_expression of Slc1a1 4 0.56 2.05 4.45
36 INT111055 Localization of Slc1a2 4 0.71 2.04 4.41
37 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
38 INT107586 Transcription of Slc17a6 6 0.61 0.79 3.68
39 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65
40 INT99535 Transcription of Slc1a2 6 0.72 1.31 3.46
41 INT105195 Positive_regulation of Negative_regulation of Slc1a1 2 0.40 0.48 3.4
42 INT124921 Negative_regulation of Negative_regulation of Slc1a1 3 0.56 0.67 3.36
43 INT132239 Localization of Slc1a1 4 0.77 1.93 3.27
44 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
45 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
46 INT198076 Gene_expression of Slc1a1 13 0.73 2.41 3.07
47 INT179756 Positive_regulation of Gene_expression of SLC1A2 8 0.38 2.95 3.06
48 INT106919 Regulation of Slc17a6 8 0.42 0.88 3.02
49 INT132240 Positive_regulation of Gene_expression of Slc1a1 2 0.66 0.62 2.96
50 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
51 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
52 INT124922 Negative_regulation of Negative_regulation of Slc1a2 2 0.35 0.07 2.79
53 INT142525 Binding of Slc1a2 4 0.45 0.94 2.65
54 INT163544 Binding of Psen1 40 0.36 15.28 2.42
55 INT153997 Negative_regulation of Gene_expression of Slc17a6 2 0.59 3.01 2.42
56 INT126033 Localization of Slc17a6 4 0.77 0.75 2.35
57 INT250283 Positive_regulation of SLC1A2 5 0.53 3.22 2.29
58 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
59 INT139932 Regulation of Slc17a6 4 0.45 2.21 2.17
60 INT179750 Negative_regulation of Gene_expression of SLC1A2 3 0.45 3.05 2.15
61 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
62 INT128272 Positive_regulation of Gene_expression of Slc17a6 3 0.47 0.66 2.03
63 INT99534 Regulation of Gene_expression of Slc1a1 2 0.48 1.67 2.01
64 INT179749 Regulation of SLC1A2 3 0.34 2.28 1.99
65 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
66 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
67 INT137518 Regulation of Slc1a1 2 0.47 0.74 1.82
68 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
69 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
70 INT137519 Binding of Slc1a1 2 0.29 0.68 1.7
71 INT99537 Positive_regulation of Transcription of Slc1a2 4 0.70 0.8 1.69
72 INT151271 Positive_regulation of Positive_regulation of Slc1a2 1 0.32 0 1.69
73 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
74 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
75 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
76 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
77 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
78 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
79 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
80 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
81 INT56439 Regulation of Positive_regulation of Slc1a1 3 0.32 1.65 1.47
82 INT305492 Negative_regulation of Localization of Slc17a6 3 0.43 1.49 1.45
83 INT305490 Transcription of Slc17a6 5 0.72 0.43 1.44
84 INT305497 Localization of Slc17a6 4 0.75 1.48 1.42
85 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
86 INT305494 Positive_regulation of Slc17a6 1 0.50 2.3 1.34
87 INT179754 Regulation of Gene_expression of SLC1A2 3 0.34 0.93 1.32
88 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
89 INT116213 Regulation of Transcription of Slc1a2 1 0.61 0.41 1.12
90 INT251225 Binding of Slc17a6 2 0.37 1.9 1.1
91 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
92 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
93 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
94 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
95 INT198074 Positive_regulation of Gene_expression of Slc1a1 2 0.65 0.25 0.89
96 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
97 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
98 INT305495 Positive_regulation of Regulation of Slc17a6 1 0.47 1.72 0.83
99 INT139931 Regulation of Gene_expression of Slc17a6 1 0.62 0.39 0.83
100 INT106920 Positive_regulation of Slc17a6 2 0.47 0.15 0.82
101 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
102 INT352657 Transcription of SLC1A2 1 0.06 0.76 0.8
103 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
104 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
105 INT198064 Negative_regulation of Gene_expression of Slc1a1 1 0.39 0.26 0.76
106 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
107 INT268729 Negative_regulation of Positive_regulation of Slc1a2 2 0.40 0.89 0.63
108 INT305498 Positive_regulation of Gene_expression of Slc17a6 1 0.50 1.13 0.54
109 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
110 INT319282 Positive_regulation of Slc1a1 1 0.43 0.17 0.5
111 INT319255 Positive_regulation of Transcription of Slc1a1 1 0.65 0.17 0.48
112 INT319272 Transcription of Slc1a1 1 0.67 0.16 0.47
113 INT305486 Negative_regulation of Transcription of Slc17a6 1 0.43 0 0.46
114 INT250276 Localization of SLC1A2 1 0.61 2.4 0.44
115 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
116 INT352656 Positive_regulation of Transcription of SLC1A2 1 0.04 0.39 0.43
117 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
118 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
119 INT193856 Localization of Psen1 19 0.73 9.79 0.41
120 INT198072 Positive_regulation of Localization of Slc1a1 1 0.40 0.1 0.39
121 INT198070 Localization of Slc1a1 1 0.63 0.1 0.39
122 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
123 INT351825 Gene_expression of SLC25A22 1 0.19 2.02 0.38
124 INT116167 Negative_regulation of Gene_expression of Slc17a6 1 0.42 0.06 0.38
125 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
126 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
127 INT198069 Regulation of Gene_expression of Slc1a1 1 0.56 0.12 0.36
128 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
129 INT313997 Regulation of Regulation of Slc1a2 1 0.06 0.66 0.29
130 INT148625 Regulation of Transcription of Slc17a6 1 0.18 0.07 0.27
131 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
132 INT106918 Negative_regulation of Slc17a6 1 0.24 0 0.27
133 INT148624 Regulation of Gene_expression of Slc17a6 1 0.31 0.07 0.27
134 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
135 INT250277 Regulation of Localization of SLC1A2 1 0.34 0.99 0.25
136 INT250278 Binding of SLC1A2 1 0.28 1.52 0.24
137 INT305487 Positive_regulation of Negative_regulation of Slc17a6 1 0.61 0.87 0.21
138 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
139 INT198077 Regulation of Slc1a1 1 0.24 0.07 0.18
140 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
141 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
142 INT198075 Binding of Slc1a1 2 0.35 1.02 0.14
143 INT268732 Negative_regulation of Binding of Slc1a2 1 0.41 0.23 0.14
144 INT268731 Regulation of Binding of Slc1a2 1 0.26 0.23 0.14
145 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
146 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
147 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
148 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
149 INT270125 Transcription of Slc1a1 1 0.10 1.76 0.09
150 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
151 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
152 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
153 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
154 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
155 INT198065 Binding of Slc1a3 3 0.30 0 0.05
156 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
157 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
158 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
159 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
160 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
161 INT270126 Positive_regulation of Transcription of Slc1a1 1 0.10 0.8 0.04
162 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
163 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
164 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
165 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
166 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
167 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
168 INT253781 Binding of Slc17a6 1 0.03 0 0
169 INT177774 Transcription of PSEN1 1 0.33 0.09 0
170 INT326806 Binding of SLC25A22 1 0.09 0.13 0
171 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
172 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox