GO:0015872

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Name dopamine transport
Categary Process
Go Slim No
Go Link GO:0015872
Unique Molecular Interactions 206
Total Molecular Interactions 353
Total Single Events 2457
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dopamine transport. They are ordered first by their pain relevance and then by number of times they were reported for dopamine transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
4 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
5 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
6 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
7 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
8 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
9 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
10 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
11 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
12 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
13 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
14 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
15 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
16 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
17 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
18 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
19 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
20 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14
21 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
22 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
23 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
24 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
25 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
26 INT46645 Binding of Gabrg1 and Chrm5 1 0.29 0.09 1
27 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
28 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
29 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
30 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
31 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
32 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
33 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
34 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
35 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
36 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
37 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
38 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
39 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
40 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
41 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
42 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
43 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
44 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
45 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
46 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63
47 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
48 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
49 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
50 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58
51 INT270935 Cpe Regulation of Phosphorylation of Slc6a3 1 0.31 0 0.57
52 INT270984 Slc6a3 Regulation of IGKC 1 0.02 0 0.53
53 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
54 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
55 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
56 INT270937 Cpe Regulation of Slc6a3 1 0.36 0 0.5
57 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48
58 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45
59 INT90642 Cpe Negative_regulation of Negative_regulation of Slc6a3 1 0.04 0 0.44
60 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
61 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
62 INT344104 Binding of Slc6a3 and Obfc1 1 0.00 0 0.43
63 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4
64 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4
65 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
66 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39
67 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
68 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
69 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39
70 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
71 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
72 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
73 INT190003 Binding of MVD and Slc6a3 1 0.13 0.19 0.37
74 INT270939 Gene_expression of Cpe Positive_regulation of Slc6a3 1 0.20 0 0.36
75 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
76 INT102341 Binding of Slc6a3 and Flvcr2 2 0.06 0 0.34
77 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
78 INT102340 Binding of Slc6a3 and Sert1 1 0.18 0 0.34
79 INT90643 Negative_regulation of Slc6a3 Positive_regulation of Th 1 0.47 0 0.3
80 INT270954 Gene_expression of Cpe Positive_regulation of Gene_expression of Slc6a3 1 0.23 0 0.28
81 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
82 INT270955 Cpe Regulation of Gene_expression of Slc6a3 1 0.14 0 0.25
83 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
84 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
85 INT270951 Regulation of Binding of Slc6a3 and Cpe 1 0.23 0 0.25
86 INT214366 Ins1 Regulation of Slc6a3 1 0.11 0.09 0.25
87 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
88 INT270940 Negative_regulation of Binding of Slc6a3 and Cpe 1 0.25 0 0.23
89 INT270948 Cpe Regulation of Regulation of Slc6a3 1 0.14 0.28 0.23
90 INT201440 Negative_regulation of Ngf Positive_regulation of Slc6a3 1 0.10 0 0.2
91 INT270947 Cpe Negative_regulation of Phosphorylation of Slc6a3 1 0.25 0 0.2
92 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2
93 INT201443 Ngf Positive_regulation of Slc6a3 1 0.11 0 0.19
94 INT184868 Binding of Slc6a3 and Lmo1 1 0.02 0.72 0.19
95 INT349505 Ptpn2 Negative_regulation of Slc6a3 1 0.19 0.7 0.16
96 INT227953 Chrm2 Regulation of Chrm5 1 0.21 0.33 0.13
97 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13
98 INT227954 Chrm4 Regulation of Chrm5 1 0.24 0.33 0.13
99 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12
100 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12
101 INT184920 Binding of Agtrap and Slc6a3 1 0.02 0.09 0.09
102 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
103 INT201446 GOPC Positive_regulation of Slc6a3 1 0.03 0.07 0.08
104 INT184917 Slc6a3 Positive_regulation of Agtrap 1 0.03 0.08 0.06
105 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
106 INT201439 Dlat Regulation of Localization of Slc6a3 1 0.04 0 0.06
107 INT321651 Binding of Slc6a3 and Uts2r 1 0.04 0.06 0.05
108 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
109 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
110 INT201442 Dlat Regulation of Slc6a3 1 0.04 0.18 0.04
111 INT270950 Binding of Slc6a3 and Tgfb1i1 1 0.02 0.23 0.04
112 INT270985 Binding of Slc6a3 and GSTK1 1 0.02 0.05 0.03
113 INT270956 Slc6a3 Positive_regulation of Cpe 1 0.29 0 0.03
114 INT270938 Binding of Pick1 and Wnt2 1 0.00 0.18 0.03
115 INT270941 Slc6a3 Positive_regulation of Binding of Cpe 1 0.29 0 0.03
116 INT89016 Oprd1 Negative_regulation of Drd1a 1 0.06 0 0
117 INT90319 Binding of Slc6a3 and Positive_regulation of Regulation of Oprl1 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for dopamine transport. They are ordered first by their pain relevance and then by number of times they were reported in dopamine transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
2 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
3 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
4 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
5 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
6 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
7 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
8 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
9 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
10 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
11 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
12 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
13 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
14 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
15 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
16 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
17 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
18 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
19 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
20 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
21 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
22 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
23 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
24 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
25 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
26 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
27 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
28 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
29 INT167600 Gene_expression of Chrm5 15 0.72 2.4 5.48
30 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
31 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
32 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
33 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
34 INT201438 Phosphorylation of Slc6a3 3 0.68 0.79 4.19
35 INT183479 Positive_regulation of Gene_expression of Slc6a3 16 0.57 0.91 4.13
36 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4
37 INT214362 Negative_regulation of Gene_expression of Slc6a3 7 0.41 1.58 3.67
38 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4
39 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
40 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
41 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09
42 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
43 INT167547 Positive_regulation of Gene_expression of Slc6a3 8 0.46 3.33 3.03
44 INT54355 Transcription of Slc6a3 6 0.61 0.28 3.02
45 INT212822 Negative_regulation of Chrm5 5 0.42 0.86 2.96
46 INT28460 Negative_regulation of Localization of Slc6a3 5 0.36 0.24 2.9
47 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
48 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
49 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
50 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48
51 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
52 INT111584 Positive_regulation of Negative_regulation of Slc6a3 4 0.47 0.68 2.31
53 INT212819 Regulation of Chrm5 2 0.44 1.64 2.22
54 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
55 INT93965 Negative_regulation of Binding of Slc6a3 5 0.42 1.39 2.07
56 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
57 INT169552 Positive_regulation of Negative_regulation of Slc6a3 3 0.50 0.51 2.05
58 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
59 INT95461 Positive_regulation of Regulation of Slc6a3 3 0.47 0 1.95
60 INT77990 Protein_catabolism of Slc6a3 6 0.72 0.99 1.84
61 INT210140 Regulation of Gene_expression of Slc6a3 1 0.62 0.83 1.82
62 INT198952 Localization of Slc6a3 3 0.75 0.68 1.62
63 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
64 INT114808 Positive_regulation of Binding of SLC6A3 4 0.50 0.63 1.45
65 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
66 INT28456 Negative_regulation of Positive_regulation of Slc6a3 2 0.32 0 1.38
67 INT99930 Positive_regulation of Gene_expression of SLC6A3 4 0.43 0.08 1.34
68 INT229116 Negative_regulation of Localization of SLC6A3 1 0.22 0.17 1.31
69 INT148262 Negative_regulation of Gene_expression of SLC6A3 2 0.38 1.66 1.29
70 INT138347 Phosphorylation of Slc6a3 2 0.71 1.01 1.26
71 INT156390 Regulation of Gene_expression of Slc6a3 2 0.37 0.28 1.22
72 INT28459 Regulation of Positive_regulation of Slc6a3 1 0.34 0 1.17
73 INT212818 Binding of Chrm5 5 0.35 1.34 1.15
74 INT113607 Positive_regulation of Pick1 1 0.48 0.82 1.13
75 INT184839 Localization of Drd1a 4 0.73 0.84 1.03
76 INT116659 Regulation of Pick1 3 0.41 0.86 1.01
77 INT152000 Regulation of Regulation of Slc6a3 1 0.44 0.68 0.99
78 INT133215 Transcription of Slc6a3 4 0.67 1.59 0.95
79 INT64690 Negative_regulation of Localization of Drd1a 2 0.09 0 0.95
80 INT74183 Positive_regulation of Localization of Drd1a 1 0.32 0.06 0.95
81 INT93969 Positive_regulation of Binding of Slc6a3 1 0.41 0.62 0.94
82 INT138346 Positive_regulation of Phosphorylation of Slc6a3 1 0.17 1.24 0.93
83 INT212820 Transcription of Chrm5 1 0.68 0.36 0.91
84 INT99668 Positive_regulation of Binding of Drd1a 2 0.43 0.89 0.87
85 INT212817 Regulation of Regulation of Chrm5 1 0.44 0.13 0.81
86 INT148263 Transcription of SLC6A3 1 0.62 0.49 0.81
87 INT210141 Positive_regulation of Localization of Slc6a3 1 0.50 0.35 0.8
88 INT270962 Negative_regulation of Phosphorylation of Slc6a3 1 0.42 0 0.8
89 INT122578 Regulation of Gene_expression of SLC6A3 3 0.34 0.2 0.75
90 INT54354 Regulation of Transcription of Slc6a3 1 0.21 0.08 0.74
91 INT201436 Positive_regulation of Phosphorylation of Slc6a3 2 0.50 0.27 0.71
92 INT146344 Negative_regulation of Regulation of Slc6a3 2 0.32 1.17 0.7
93 INT106106 Gene_expression of Pick1 3 0.70 0.66 0.68
94 INT153157 Regulation of Regulation of Drd1a 2 0.25 0.2 0.66
95 INT184848 Positive_regulation of Transcription of Drd1a 1 0.26 0.93 0.65
96 INT140306 Regulation of Binding of Drd1a 1 0.20 0.36 0.64
97 INT72516 Regulation of Binding of Drd1a 2 0.44 0.4 0.63
98 INT146345 Regulation of Binding of Slc6a3 1 0.34 0.22 0.61
99 INT212816 Positive_regulation of Chrm5 1 0.46 0.19 0.6
100 INT90637 Negative_regulation of Positive_regulation of Slc6a3 1 0.41 0 0.6
101 INT184911 Regulation of Negative_regulation of Slc6a3 1 0.36 0.06 0.59
102 INT119054 Negative_regulation of Binding of SLC6A3 2 0.43 0 0.54
103 INT89215 Negative_regulation of Binding of Slc6a3 1 0.26 0.06 0.48
104 INT281468 Positive_regulation of Positive_regulation of Slc6a3 1 0.42 0.34 0.4
105 INT106108 Phosphorylation of Pick1 1 0.54 0.07 0.39
106 INT48566 Regulation of Transcription of Drd1a 1 0.32 0 0.37
107 INT101780 Regulation of Regulation of Slc6a3 1 0.26 0 0.3
108 INT136052 Negative_regulation of Negative_regulation of Drd1a 1 0.13 0.66 0.27
109 INT341786 Positive_regulation of Phosphorylation of SLC6A3 1 0.16 0.07 0.26
110 INT341782 Phosphorylation of SLC6A3 1 0.27 0.07 0.26
111 INT270965 Positive_regulation of Positive_regulation of Slc6a3 1 0.36 0 0.25
112 INT274009 Positive_regulation of Positive_regulation of SLC6A3 1 0.43 0.09 0.25
113 INT270963 Positive_regulation of Binding of Slc6a3 1 0.36 0 0.25
114 INT326598 Negative_regulation of Negative_regulation of SLC6A3 1 0.28 0.65 0.24
115 INT227948 Localization of Chrm5 1 0.69 0.28 0.17
116 INT227950 Negative_regulation of Localization of Chrm5 1 0.39 0.28 0.17
117 INT270959 Binding of Pick1 2 0.35 0.2 0.16
118 INT349491 Negative_regulation of Transcription of Slc6a3 1 0.22 0.7 0.16
119 INT270974 Negative_regulation of Protein_catabolism of Slc6a3 1 0.42 0 0.15
120 INT270976 Positive_regulation of Protein_catabolism of Slc6a3 1 0.34 0 0.15
121 INT270970 Regulation of Binding of Slc6a3 1 0.32 0.44 0.14
122 INT320585 Negative_regulation of Gene_expression of Pick1 1 0.31 0.1 0.11
123 INT320586 Positive_regulation of Gene_expression of Pick1 1 0.50 0.1 0.11
124 INT270973 Regulation of Protein_catabolism of Slc6a3 1 0.44 0 0.09
125 INT341783 Positive_regulation of Localization of SLC6A3 1 0.14 0.08 0.09
126 INT320584 Negative_regulation of Pick1 1 0.31 0.09 0.08
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