GO:0015991

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Name ATP hydrolysis coupled proton transport
Categary Process
Go Slim No
Go Link GO:0015991
Unique Molecular Interactions 79
Total Molecular Interactions 99
Total Single Events 323
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ATP hydrolysis coupled proton transport. They are ordered first by their pain relevance and then by number of times they were reported for ATP hydrolysis coupled proton transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41
3 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
4 INT214408 ATP1A4 Regulation of DNAH8 1 0.04 1.01 0.94
5 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
6 INT214409 ATP1A4 Regulation of CAPN1 1 0.01 1.01 0.93
7 INT16438 Atp6v0d2 Regulation of Localization of Lnpep 1 0.01 0 0.81
8 INT16439 Atp6v0d2 Regulation of Localization of Avp 1 0.02 0 0.81
9 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73
10 INT38512 Binding of Cyp2c22 and Atp6v1c2 1 0.00 0.17 0.73
11 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
12 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62
13 INT123465 Oprl1 Positive_regulation of ATP5G3 1 0.22 0 0.57
14 INT353698 NA Positive_regulation of Atp6v0a1 1 0.00 0.67 0.44
15 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41
16 INT189300 Atp6v1e1 Regulation of Gene_expression of Prl 1 0.03 0.29 0.39
17 INT216738 Binding of ATP6V0A1 and TCFL5 1 0.01 0.06 0.38
18 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37
19 INT301289 Positive_regulation of Clec5a Positive_regulation of Gene_expression of Atp6v0d2 1 0.02 1.01 0.28
20 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
21 INT278582 Atp6v1e1 Positive_regulation of Positive_regulation of Tac1 1 0.15 0.13 0.24
22 INT266038 Atp6v1e1 Positive_regulation of Positive_regulation of Mapk1 1 0.07 0.64 0.22
23 INT216841 TCIRG1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
24 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
25 INT252423 Binding of TCIRG1 and SLURP1 1 0.00 0.33 0.16
26 INT252428 Negative_regulation of Binding of TCIRG1 and SLURP1 1 0.00 0.33 0.16
27 INT173942 Binding of DMD and Atp6v1e1 1 0.00 0 0.13
28 INT278583 Ppt1 Negative_regulation of Gene_expression of Atp6v1e1 1 0.05 0 0.13
29 INT243319 Binding of ATP6V0A1 and BBC3 1 0.07 0.59 0.13
30 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12
31 INT279804 ATP6V0A2 Regulation of MCF2 1 0.00 1.76 0.12
32 INT189301 Atp6v1e1 Positive_regulation of Positive_regulation of Htr2a 1 0.01 1.13 0.11
33 INT189298 Atp6v1e1 Positive_regulation of Positive_regulation of Htr1a 1 0.00 1.15 0.11
34 INT278573 Atp6v1e1 Regulation of Gene_expression of Tacr3 1 0.17 0.07 0.09
35 INT290166 Atp6v1e1 Positive_regulation of IFNA1 1 0.07 0 0.08
36 INT278580 Olfr714 Regulation of Atp6v1e1 1 0.03 0 0.08
37 INT142745 Atp6v1e1 Regulation of Gene_expression of Trpv6 1 0.07 0 0.07
38 INT290158 Binding of Ache and Atp6v1e1 1 0.19 0 0.07
39 INT142746 Atp6v1e1 Regulation of Trpv6 1 0.17 0 0.06
40 INT324559 Atp6v1e1 Positive_regulation of Localization of Kiss1 1 0.16 0.52 0.06
41 INT340727 Binding of ATP5G3 and CSPG5 1 0.01 2.03 0.06
42 INT305877 Pcx Regulation of Gene_expression of Atp6v0a2 1 0.01 1.45 0.04
43 INT305885 Pcx Positive_regulation of Gene_expression of Atp6v0a2 1 0.01 1.45 0.04
44 INT290163 Atp6v1e1 Positive_regulation of Ighm 1 0.12 0.26 0.04
45 INT278572 Atp6v1e1 Negative_regulation of Gene_expression of Tacr3 1 0.22 0 0.03
46 INT237089 Binding of Bnip3l and Atp6v0a4 1 0.12 1.67 0.03
47 INT340741 Binding of ATP5G3 and Gma3 1 0.00 0.96 0.03
48 INT324564 Atp6v1e1 Positive_regulation of Kiss1 1 0.15 0.21 0
49 INT290155 Atp6v1e1 Positive_regulation of Gene_expression of Irf7 1 0.14 0.21 0
50 INT186955 Binding of Atp6v1e1 and Hps1 1 0.01 0.07 0
51 INT279802 ATP6V0A2 Negative_regulation of ERBB3 1 0.00 1.96 0
52 INT297005 Binding of ATP12A and ATP6V0A1 1 0.04 0.3 0
53 INT332960 Atp6v1e1 Negative_regulation of Ppara 1 0.18 0.99 0
54 INT332965 Binding of Atp6v1e1 and Ppara 1 0.15 0.36 0
55 INT290159 Atp6v1e1 Positive_regulation of Localization of Ighm 1 0.13 0.05 0
56 INT290168 Atp6v1e1 Regulation of Localization of IFNA1 1 0.07 0.19 0
57 INT290164 Atp6v1e1 Positive_regulation of Gene_expression of Cd86 1 0.18 0.17 0
58 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0
59 INT305884 Atp6v0a2 Regulation of Alms1 1 0.00 0 0
60 INT290160 Atp6v1e1 Positive_regulation of Cd40 1 0.24 0.5 0
61 INT290170 Atp6v1e1 Positive_regulation of Gene_expression of IFNA1 1 0.07 0.15 0
62 INT332969 Binding of Atp6v1e1 and Positive_regulation of Ppara 1 0.21 0 0
63 INT290154 Atp6v1e1 Positive_regulation of Gene_expression of Ighm 1 0.13 0.23 0
64 INT278577 Atp6v1e1 Regulation of Gene_expression of Tac2 1 0.16 0.07 0
65 INT305880 Pcx Regulation of Atp6v0a2 1 0.01 0 0
66 INT278575 Atp6v1e1 Negative_regulation of Gene_expression of Tac1 1 0.14 0 0
67 INT289294 Binding of CD59 and Atp6ap1 1 0.10 0.51 0
68 INT332963 Atp6v1e1 Negative_regulation of Binding of Crebbp 1 0.08 0 0
69 INT290167 Atp6v1e1 Positive_regulation of Localization of IFNA1 1 0.07 0.33 0
70 INT332973 Atp6v1e1 Positive_regulation of Ppara 1 0.19 0 0
71 INT290156 Atp6v1e1 Positive_regulation of Cd86 1 0.26 0.5 0
72 INT332959 Atp6v1e1 Negative_regulation of Gene_expression of Ppara 1 0.18 1.33 0
73 INT279800 ATP6V0A2 Positive_regulation of Phosphorylation of MAPK8 1 0.01 1.03 0
74 INT332967 Atp6v1e1 Regulation of Ppara 1 0.11 0.47 0
75 INT289298 Negative_regulation of Binding of CD59 and Atp6ap1 1 0.12 0.51 0
76 INT279803 ATP6V0A2 Negative_regulation of MCF2 1 0.00 1.95 0
77 INT290162 Atp6v1e1 Regulation of Gene_expression of Cd80 1 0.16 0.28 0
78 INT332964 Binding of Atp6v1e1 and Tmed4 1 0.02 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ATP hydrolysis coupled proton transport. They are ordered first by their pain relevance and then by number of times they were reported in ATP hydrolysis coupled proton transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT216754 Binding of ATP6V0A1 5 0.11 0.71 4.98
2 INT173926 Positive_regulation of Atp6v1e1 21 0.27 11.39 4.24
3 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
4 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
5 INT52878 Positive_regulation of ATP6V0A1 9 0.54 1.35 2.92
6 INT102734 Gene_expression of Atp6v0a2 18 0.50 6.28 2.76
7 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
8 INT142741 Gene_expression of Atp6v1e1 28 0.31 9.41 2.34
9 INT49250 Regulation of Atp6v0d2 5 0.08 1.54 2.04
10 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95
11 INT12849 Negative_regulation of Atp6v0a1 5 0.51 0.64 1.89
12 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
13 INT127767 Negative_regulation of Atp6v1e1 9 0.23 5.66 1.52
14 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
15 INT173928 Regulation of Atp6v1e1 11 0.16 3.77 1.43
16 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
17 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37
18 INT216850 Binding of TCIRG1 3 0.10 0.44 1.37
19 INT103960 Gene_expression of ATP1A4 4 0.73 3.05 1.34
20 INT179217 Positive_regulation of ATP1A4 2 0.11 0.91 1.34
21 INT189287 Binding of Atp6v1e1 7 0.19 6.9 1.14
22 INT278100 Regulation of ATP6V0A1 5 0.19 1.5 1.07
23 INT1041 Positive_regulation of Atp6v0a1 5 0.66 2.4 0.93
24 INT214417 Regulation of ATP1A4 1 0.38 1.01 0.93
25 INT52879 Negative_regulation of ATP6V0A1 2 0.24 0.64 0.82
26 INT123464 Binding of ATP5G3 3 0.18 1.92 0.79
27 INT21246 Negative_regulation of ATP1A4 3 0.10 3.3 0.79
28 INT123463 Gene_expression of ATP5G3 5 0.37 2.25 0.75
29 INT173930 Positive_regulation of Gene_expression of Atp6v1e1 4 0.17 0.46 0.71
30 INT24408 Positive_regulation of Negative_regulation of Atp6v0a1 1 0.36 0 0.71
31 INT121618 Negative_regulation of Atp6v1c2 1 0.43 0.66 0.7
32 INT1136 Regulation of Atp6v0a1 3 0.29 0.2 0.65
33 INT252448 Regulation of TCIRG1 1 0.01 0.35 0.59
34 INT259408 Gene_expression of Atp6v0d2 5 0.09 2.01 0.54
35 INT206913 Localization of Atp6v1e1 8 0.32 3.55 0.43
36 INT216856 Positive_regulation of TCIRG1 2 0.11 0.29 0.43
37 INT278096 Negative_regulation of Binding of ATP6V0A1 1 0.07 0.11 0.43
38 INT45323 Binding of Atp6v0a1 1 0.18 0.23 0.37
39 INT179223 Regulation of Gene_expression of ATP1A4 1 0.02 1.23 0.37
40 INT189284 Positive_regulation of Negative_regulation of Atp6v1e1 2 0.20 1.82 0.28
41 INT179215 Positive_regulation of Gene_expression of ATP1A4 1 0.06 0.24 0.28
42 INT278565 Negative_regulation of Positive_regulation of Atp6v1e1 1 0.12 0 0.28
43 INT179220 Negative_regulation of Gene_expression of ATP1A4 1 0.04 1.11 0.24
44 INT189297 Transcription of Atp6v1e1 2 0.24 1.54 0.23
45 INT239509 Binding of Atp6v0a2 2 0.09 0 0.22
46 INT278095 Positive_regulation of Positive_regulation of ATP6V0A1 1 0.08 0 0.21
47 INT237079 Positive_regulation of Atp6v0a4 2 0.17 1.77 0.19
48 INT176241 Negative_regulation of Gene_expression of Atp6v1e1 5 0.17 2.16 0.17
49 INT15630 Regulation of ATP5G3 1 0.22 0 0.17
50 INT114012 Negative_regulation of Binding of ATP1A2 1 0.45 1.01 0.14
51 INT292765 Localization of Atp6v0a2 1 0.17 0.72 0.14
52 INT305864 Regulation of Gene_expression of Atp6v0a2 1 0.03 1.5 0.12
53 INT278101 Regulation of Binding of ATP6V0A1 1 0.04 0 0.12
54 INT254475 Positive_regulation of Gene_expression of Atp6v0a2 1 0.11 0 0.11
55 INT1040 Positive_regulation of Positive_regulation of Atp6v0a1 1 0.47 0.52 0.1
56 INT188897 Positive_regulation of ATP5G3 2 0.21 0.76 0.05
57 INT124244 Negative_regulation of Gene_expression of Atp6v0a4 1 0.16 0.77 0.05
58 INT124245 Gene_expression of Atp6v0a4 1 0.29 0.77 0.05
59 INT124248 Negative_regulation of Atp6v0a4 1 0.16 0.77 0.05
60 INT189294 Regulation of Negative_regulation of Atp6v1e1 1 0.15 1 0.05
61 INT297033 Localization of ATP6V0A1 2 0.50 1.07 0.04
62 INT287250 Negative_regulation of ATP5G3 1 0.03 0.29 0.04
63 INT194067 Regulation of Atp6v0a2 2 0.15 0.62 0
64 INT305863 Regulation of Localization of Atp6v0a2 1 0.02 0 0
65 INT279807 Regulation of ATP6V0A2 1 0.01 0.86 0
66 INT239510 Positive_regulation of Atp6v0a2 1 0.02 0 0
67 INT290137 Regulation of Regulation of Atp6v1e1 1 0.11 0.16 0
68 INT211817 Protein_catabolism of ATP5G3 1 0.07 0.05 0
69 INT259402 Regulation of Binding of Atp6v0d2 1 0.06 0 0
70 INT324552 Positive_regulation of Transcription of Atp6v1e1 1 0.13 0.34 0
71 INT297025 Regulation of Gene_expression of ATP6V0A1 1 0.32 0.53 0
72 INT324497 Positive_regulation of Binding of Atp6v1e1 1 0.13 0 0
73 INT259410 Localization of Atp6v0d2 1 0.12 0 0
74 INT324494 Regulation of Localization of Atp6v1e1 1 0.10 0.09 0
75 INT259407 Binding of Atp6v0d2 1 0.07 0 0
76 INT290130 Regulation of Gene_expression of Atp6v1e1 1 0.18 0 0
77 INT292762 Regulation of Binding of Atp6v0a2 1 0.10 0 0
78 INT324500 Regulation of Positive_regulation of Atp6v1e1 1 0.06 0.17 0
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