GO:0016055

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Name Wnt receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0016055
Unique Molecular Interactions 662
Total Molecular Interactions 884
Total Single Events 6336
Pain Genes Associated 99

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Wnt receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for Wnt receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
2 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38
3 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
4 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
5 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
6 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
7 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
8 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
9 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
10 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
11 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
12 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04
13 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
14 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
15 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
16 INT203101 Binding of Aes and Mtx1 2 0.25 0.24 0.88
17 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
18 INT197470 Binding of Sostdc1 and Hbtq 1 0.00 0.87 0.87
19 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
20 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
21 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
22 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
23 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
24 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
25 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
26 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
27 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
28 INT124385 GRK6 Negative_regulation of MC1R 1 0.42 0.42 0.77
29 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
30 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76
31 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75
32 INT120848 Sp6 Positive_regulation of Gene_expression of Ndp 1 0.14 0.52 0.74
33 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
34 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
35 INT140236 GRK6 Positive_regulation of Binding of MC1R 1 0.52 0.31 0.68
36 INT140234 Gene_expression of GRK6 Positive_regulation of Gene_expression of MC1R 1 0.52 0.31 0.68
37 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
38 INT61798 Binding of NDP and POMC 2 0.22 0 0.66
39 INT253585 Binding of IFN1@ and Csnk2a2 1 0.24 1.35 0.64
40 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
41 INT209131 Binding of Bcl2a1a and Drd2 1 0.22 0.45 0.62
42 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
43 INT71110 Binding of MC1R and NDP 1 0.10 0 0.57
44 INT239500 Binding of Aes and Atic 1 0.20 0.4 0.56
45 INT45258 SLAMF6 Positive_regulation of Drd2 1 0.00 0 0.55
46 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
47 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55
48 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55
49 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
50 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54
51 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
52 INT25414 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.38 0 0.53
53 INT165045 Drd2 Regulation of Cpe 1 0.07 0 0.52
54 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
55 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
56 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52
57 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
58 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
59 INT72230 Binding of BTRC and EMID1 1 0.00 0 0.49
60 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49
61 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
62 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47
63 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
64 INT147404 NDP Positive_regulation of MC1R 1 0.22 0.25 0.45
65 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
66 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
67 INT16586 Binding of Drd2 and Nts 1 0.12 0 0.43
68 INT148548 Cd44 Positive_regulation of Regulation of NPEPPS 1 0.00 0.29 0.42
69 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
70 INT36009 Binding of Drd2 and Prl 1 0.01 1.05 0.42
71 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
72 INT61799 Negative_regulation of Binding of NDP and POMC 1 0.20 0 0.41
73 INT148547 Cd44 Positive_regulation of NPEPPS 1 0.00 0.29 0.41
74 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
75 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
76 INT38306 Binding of Dpagt1 and DACT1 1 0.01 0.42 0.39
77 INT38305 Binding of DACT1 and Gpt 1 0.01 0.43 0.39
78 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38
79 INT334835 Negative_regulation of Binding of Drd2 and Ncs1 1 0.04 0.56 0.38
80 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
81 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38
82 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38
83 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
84 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
85 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
86 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
87 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
88 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
89 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
90 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
91 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
92 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
93 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
94 INT124380 Prodh2 Regulation of Wnt2 1 0.00 0.63 0.35
95 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
96 INT72180 Binding of CTRC and Cela1 1 0.00 0.65 0.34
97 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
98 INT334836 Ncs1 Regulation of Drd2 1 0.02 0.48 0.33
99 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
100 INT109894 Drd2 Positive_regulation of FOS 1 0.01 0 0.33
101 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32
102 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
103 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
104 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
105 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
106 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
107 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
108 INT83569 Grk5 Regulation of Oprk1 1 0.02 0 0.29
109 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28
110 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
111 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28
112 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
113 INT97594 Penk Regulation of Gene_expression of Drd2 1 0.15 0.1 0.28
114 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
115 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
116 INT118860 MCC Positive_regulation of Phosphorylation of STAT3 1 0.01 0.1 0.27
117 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
118 INT135947 MCC Regulation of GDF15 1 0.11 1.58 0.27
119 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25
120 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
121 INT136364 Cpz Positive_regulation of Localization of Tnf 1 0.29 0.36 0.25
122 INT213804 Binding of Mitf and Tfeb 1 0.24 0.81 0.24
123 INT253563 Csnk2a2 Regulation of Phosphorylation of Stat1 1 0.16 0.58 0.24
124 INT348637 Binding of TLE4 and OLFM1 1 0.01 1.67 0.24
125 INT72231 Negative_regulation of Binding of NFKBIL1 and BTRC 1 0.00 0 0.24
126 INT164136 Binding of DRD2 and Prl 1 0.09 0 0.22
127 INT164135 Binding of Drd2 and Prl 1 0.04 0 0.22
128 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
129 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
130 INT183644 Nos2 Positive_regulation of Gene_expression of Macf1 1 0.05 0.84 0.21
131 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
132 INT69254 Drd2 Regulation of Gene_expression of Pomc 1 0.01 0 0.2
133 INT121583 Negative_regulation of GSK3A Negative_regulation of Gene_expression of GDF15 1 0.11 0.49 0.2
134 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19
135 INT168828 Binding of DDB1 and UBR1 1 0.00 0.67 0.19
136 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19
137 INT299435 Rspo3 Positive_regulation of Wnt2 1 0.06 0.35 0.19
138 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
139 INT247507 Grk6 Regulation of LTB4R 1 0.02 0.2 0.18
140 INT307453 Bdnf Positive_regulation of Phosphorylation of Gsk3a 1 0.06 0.16 0.18
141 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
142 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
143 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
144 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
145 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
146 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
147 INT295439 Binding of AES and IFNA1 1 0.25 0.46 0.17
148 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
149 INT119561 TLE4 Negative_regulation of Positive_regulation of CD1D 1 0.00 0.68 0.16
150 INT224092 Adrbk1 Regulation of Grk5 1 0.08 0 0.16
151 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
152 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
153 INT119559 TLE4 Negative_regulation of Positive_regulation of IL4 1 0.01 0.67 0.15
154 INT213817 Phosphorylation of Tfe3 Positive_regulation of Mitf 1 0.22 1.22 0.15
155 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15
156 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15
157 INT213807 Mitf Positive_regulation of Spg21 1 0.05 1.2 0.15
158 INT119562 TLE4 Negative_regulation of Positive_regulation of TNF 1 0.00 0.67 0.15
159 INT119560 TLE4 Negative_regulation of Positive_regulation of IL5 1 0.01 0.67 0.15
160 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
161 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
162 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14
163 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
164 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
165 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14
166 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13
167 INT227957 Chrm4 Regulation of Localization of Drd2 1 0.19 0.38 0.13
168 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13
169 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
170 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
171 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
172 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
173 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
174 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
175 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
176 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13
177 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
178 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
179 INT227959 Drd2 Regulation of Chrm4 1 0.08 0.38 0.13
180 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13
181 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
182 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
183 INT224127 Grk5 Positive_regulation of Phosphorylation of Adora3 1 0.06 0 0.13
184 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
185 INT202255 Binding of DRD2 and TCN1 1 0.16 0 0.12
186 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
187 INT224090 Binding of Grk6 and Grk4 1 0.06 0 0.12
188 INT224088 Binding of Grk5 and Grk4 1 0.07 0 0.12
189 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
190 INT350343 Csnk2a2 Regulation of Grin1 1 0.11 0.09 0.11
191 INT289765 Akt1 Regulation of Phosphorylation of Gsk3a 1 0.05 0.45 0.11
192 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11
193 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
194 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11
195 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
196 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11
197 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
198 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11
199 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
200 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for Wnt receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in Wnt receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
2 INT13501 Binding of Drd2 65 0.48 23.76 35.6
3 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
4 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
5 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
6 INT12484 Binding of Drd2 45 0.48 15.17 24.72
7 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
8 INT49774 Binding of DRD2 48 0.48 17.42 20.73
9 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
10 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
11 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
12 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
13 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
14 INT158070 Localization of Aes 23 0.65 19.93 10.9
15 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
16 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16
17 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
18 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
19 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
20 INT105839 Positive_regulation of Grk5 5 0.70 0.35 9.2
21 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
22 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
23 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
24 INT150422 Positive_regulation of Aes 24 0.43 15.63 8
25 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
26 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
27 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
28 INT64523 Binding of Ndp 10 0.33 2.72 7.29
29 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
30 INT264641 Binding of AES 25 0.42 18.56 6.98
31 INT52180 Binding of Aes 38 0.42 23.16 6.7
32 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
33 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
34 INT24460 Localization of Drd2 12 0.73 2.96 6.46
35 INT116641 Phosphorylation of Gsk3a 12 0.71 4.3 6.22
36 INT86772 Localization of Drd2 14 0.80 1.93 6.17
37 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
38 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93
39 INT188844 Gene_expression of AES 44 0.58 33.94 5.85
40 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
41 INT6681 Positive_regulation of Gene_expression of Drd2 10 0.65 1.78 5.78
42 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6
43 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
44 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
45 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
46 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
47 INT201130 Localization of AES 31 0.63 25.45 5.12
48 INT197458 Positive_regulation of Sostdc1 11 0.01 3.02 4.87
49 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
50 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
51 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
52 INT128746 Negative_regulation of Gsk3a 11 0.52 8.43 4.61
53 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
54 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5
55 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48
56 INT71676 Transcription of DRD2 5 0.69 1.19 4.47
57 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
58 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
59 INT48411 Gene_expression of Cd44 35 0.77 27.05 4.29
60 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
61 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25
62 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
63 INT197459 Gene_expression of Sostdc1 10 0.01 1.04 4.11
64 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
65 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
66 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
67 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
68 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
69 INT99593 Gene_expression of Grk6 3 0.78 3.19 3.52
70 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
71 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5
72 INT122438 Transcription of Grk5 1 0.72 0 3.46
73 INT83565 Gene_expression of Grk5 5 0.55 0.16 3.39
74 INT275878 Positive_regulation of Gene_expression of Aes 4 0.23 4.54 3.39
75 INT21662 Gene_expression of Cpz 4 0.51 1.14 3.36
76 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34
77 INT116538 Negative_regulation of GRK6 1 0.48 0.84 3.31
78 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22
79 INT102209 Negative_regulation of Gene_expression of Drd2 5 0.59 0.46 3.17
80 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
81 INT122441 Regulation of Grk5 1 0.62 0 3.13
82 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
83 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
84 INT14485 Positive_regulation of Cela1 15 0.44 10.55 3.01
85 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94
86 INT54749 Binding of BTRC 7 0.09 0.88 2.9
87 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
88 INT36886 Transcription of Myc 6 0.69 3.16 2.86
89 INT105837 Regulation of Gene_expression of Grk5 1 0.44 0.16 2.68
90 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
91 INT108468 Negative_regulation of Gene_expression of Drd2 3 0.41 0.67 2.58
92 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
93 INT92000 Gene_expression of Gsk3a 12 0.18 4.12 2.39
94 INT105838 Negative_regulation of Grk5 2 0.43 0.1 2.37
95 INT94984 Regulation of Grk6 1 0.42 0 2.34
96 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
97 INT15290 Gene_expression of Cela1 17 0.52 7.56 2.22
98 INT121589 Negative_regulation of GSK3A 10 0.53 9.11 2.22
99 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
100 INT103881 Positive_regulation of Binding of DRD2 4 0.69 2.01 2.18
101 INT124389 Gene_expression of GRK6 3 0.70 1.14 2.16
102 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
103 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
104 INT248325 Positive_regulation of Localization of Aes 4 0.26 1.88 2.07
105 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
106 INT25411 Positive_regulation of Positive_regulation of Drd2 2 0.48 0.5 1.98
107 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
108 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
109 INT61802 Binding of NDP 6 0.28 0 1.85
110 INT275875 Negative_regulation of Localization of Aes 2 0.19 3.87 1.8
111 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
112 INT41515 Negative_regulation of CELA1 3 0.51 2.37 1.73
113 INT3818 Regulation of Apc 13 0.39 12.52 1.68
114 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
115 INT292052 Regulation of Gene_expression of Csnk1a1 1 0.47 2.5 1.62
116 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
117 INT153869 Positive_regulation of Grk6 1 0.47 1.7 1.61
118 INT15363 Gene_expression of CELA1 10 0.78 3.22 1.59
119 INT38893 Localization of CELA1 6 0.70 2.36 1.57
120 INT261849 Positive_regulation of Phosphorylation of Gsk3a 3 0.14 1.15 1.57
121 INT54750 Gene_expression of BTRC 4 0.14 0.99 1.55
122 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
123 INT105603 Binding of Cpz 2 0.31 1.92 1.54
124 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
125 INT153870 Negative_regulation of Gene_expression of Grk6 1 0.43 1.53 1.47
126 INT173716 Positive_regulation of Cd44 7 0.44 4.65 1.45
127 INT94987 Negative_regulation of Grk6 2 0.40 0 1.45
128 INT206244 Binding of CD24 7 0.48 5.71 1.43
129 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43
130 INT75062 Regulation of Transcription of Drd2 1 0.51 0 1.41
131 INT21523 Positive_regulation of Ctnnd1 1 0.27 0.35 1.4
132 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
133 INT220177 Binding of Apc 21 0.37 15.34 1.37
134 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37
135 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
136 INT116265 Binding of Myc 9 0.36 4.28 1.36
137 INT94982 Gene_expression of Grk6 2 0.56 0 1.32
138 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
139 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
140 INT163506 Binding of Gsk3a 4 0.32 1.41 1.31
141 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
142 INT126411 Gene_expression of Csnk2a2 11 0.78 1.59 1.3
143 INT126408 Negative_regulation of Csnk2a2 3 0.38 1.75 1.3
144 INT253552 Positive_regulation of Csnk2a2 10 0.41 1.91 1.26
145 INT109272 Negative_regulation of Binding of DRD2 2 0.36 0.76 1.26
146 INT191804 Transcription of CD24 10 0.72 12.43 1.25
147 INT203099 Negative_regulation of Aes 3 0.25 0.82 1.25
148 INT123924 Positive_regulation of Gene_expression of Cd44 2 0.46 1.11 1.25
149 INT15663 Regulation of Transcription of Drd2 2 0.26 0.1 1.25
150 INT191485 Positive_regulation of Gene_expression of Cpz 1 0.10 0.09 1.25
151 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22
152 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
153 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
154 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
155 INT77216 Localization of DRD2 3 0.75 0 1.19
156 INT116536 Binding of GRK6 1 0.31 0.3 1.19
157 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
158 INT94977 Positive_regulation of Grk6 1 0.47 0 1.17
159 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
160 INT242414 Regulation of Aes 5 0.23 1.82 1.16
161 INT124008 Positive_regulation of Wwox 2 0.67 7.64 1.16
162 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
163 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
164 INT61800 Negative_regulation of Binding of NDP 3 0.24 0 1.14
165 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
166 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
167 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
168 INT135390 Binding of Cd44 3 0.45 1.91 1.09
169 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
170 INT292071 Regulation of Negative_regulation of Csnk1a1 1 0.34 0.64 1.07
171 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
172 INT178483 Gene_expression of Col18a1 12 0.75 11.87 1.03
173 INT64525 Negative_regulation of Binding of Ndp 4 0.10 0.31 1.03
174 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
175 INT17715 Positive_regulation of CELA1 8 0.61 3.76 1
176 INT124374 Binding of Wnt2 21 0.31 10.16 0.99
177 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99
178 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
179 INT71747 Positive_regulation of Prkaa2 19 0.46 8.76 0.98
180 INT78210 Gene_expression of MCC 7 0.65 1.8 0.98
181 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
182 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
183 INT292066 Negative_regulation of Gene_expression of Csnk1a1 1 0.32 2.01 0.95
184 INT122439 Positive_regulation of Transcription of Grk5 1 0.70 0 0.94
185 INT17894 Regulation of Myc 10 0.60 5.65 0.93
186 INT135392 Localization of Cd44 1 0.75 1.74 0.93
187 INT76807 Binding of MCC 4 0.36 0.54 0.92
188 INT253940 Gene_expression of Gsk3a 1 0.08 2.82 0.92
189 INT105070 Localization of Ndp 1 0.57 0.93 0.91
190 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9
191 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
192 INT253938 Positive_regulation of Gsk3a 3 0.06 3.4 0.9
193 INT292067 Negative_regulation of Negative_regulation of Csnk1a1 1 0.32 0.56 0.9
194 INT292063 Positive_regulation of Positive_regulation of Csnk1a1 1 0.38 1.46 0.9
195 INT257893 Negative_regulation of Positive_regulation of Sostdc1 1 0.01 0 0.9
196 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89
197 INT242152 Transcription of Wnt2 8 0.57 5.22 0.88
198 INT242134 Localization of Apc 8 0.74 4.83 0.88
199 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
200 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86
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