GO:0016064

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Name immunoglobulin mediated immune response
Categary Process
Go Slim No
Go Link GO:0016064
Unique Molecular Interactions 254
Total Molecular Interactions 374
Total Single Events 2442
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for immunoglobulin mediated immune response. They are ordered first by their pain relevance and then by number of times they were reported for immunoglobulin mediated immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
2 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
3 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
4 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
5 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
6 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
7 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
8 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
9 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
10 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
11 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
12 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
13 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
14 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
15 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
16 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
17 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
18 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
19 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
20 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
21 INT316690 Binding of Myd88 and Il1 2 0.06 1.75 0.66
22 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
23 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
24 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
25 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
26 INT122427 Ighm Positive_regulation of Positive_regulation of P9Ehs1 1 0.00 0 0.56
27 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
28 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
29 INT119030 Binding of POMC and Ighg1 1 0.06 0 0.52
30 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
31 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
32 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
33 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
34 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
35 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
36 INT122426 Binding of Hint1 and Ighm 1 0.00 0 0.5
37 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
38 INT203150 Binding of Ighg2b and IgG2a 1 0.11 1.35 0.47
39 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
40 INT68252 Penk Positive_regulation of Transcription of Ighg1 1 0.44 0 0.44
41 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43
42 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
43 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
44 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
45 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39
46 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
47 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
48 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
49 INT112020 Binding of Ighg1 and IgG2a 2 0.25 0.36 0.36
50 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
51 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
52 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
53 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
54 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
55 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
56 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
57 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
58 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
59 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
60 INT203085 Positive_regulation of Binding of Il1a and Myd88 1 0.07 0.65 0.32
61 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
62 INT203087 Binding of Il1a and Myd88 1 0.05 0.65 0.31
63 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
64 INT284047 Vtcn1 Negative_regulation of Gene_expression of Ighg2b 1 0.05 0.68 0.3
65 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
66 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
67 INT324825 Binding of Chuk and Myd88 1 0.03 0.86 0.28
68 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
69 INT288205 Binding of Cd14 and Myd88 1 0.10 0.57 0.28
70 INT324806 Positive_regulation of Binding of Chuk and Myd88 1 0.04 0.86 0.28
71 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
72 INT256063 Myd88 Positive_regulation of Gene_expression of Mcpt1 1 0.13 0.56 0.27
73 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
74 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
75 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25
76 INT295269 S100a8 Regulation of Irf7 1 0.01 0.28 0.24
77 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
78 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23
79 INT292556 Binding of F2RL1 and TLR4 1 0.05 0.52 0.22
80 INT343910 TLR4 Regulation of Gene_expression of Icam1 1 0.04 1.3 0.22
81 INT292557 Binding of F2RL1 and MYD88 1 0.08 0.52 0.22
82 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21
83 INT254219 Binding of Myd88 and Tlr2 2 0.16 0.6 0.2
84 INT348789 Positive_regulation of Binding of MYD88 and Tlr4 1 0.46 0.93 0.2
85 INT188566 TLR4 Regulation of Gene_expression of PRF1 1 0.01 0.2 0.2
86 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19
87 INT343827 MIRLET7I Regulation of Gene_expression of TLR4 1 0.00 0.13 0.19
88 INT159795 Tnf Positive_regulation of TLR4 1 0.01 0.42 0.19
89 INT159796 Tnf Positive_regulation of Gene_expression of TLR4 1 0.02 0.42 0.19
90 INT353808 HLA-DMA Regulation of HLA-B 1 0.00 1.72 0.19
91 INT139302 Binding of CRP and TLR4 1 0.38 1.18 0.19
92 INT337310 PTAFR Regulation of Gene_expression of TLR4 1 0.24 0.8 0.18
93 INT179504 Tlr4 Regulation of Myd88 1 0.07 0.29 0.17
94 INT153347 Binding of TLR4 and Cd14 1 0.10 0.17 0.17
95 INT254214 Binding of Myd88 and Tirap 1 0.15 0.55 0.17
96 INT116443 LY9 Negative_regulation of Positive_regulation of NFKB1 1 0.12 0 0.17
97 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 0.35 1.16 0.17
98 INT116440 LY9 Negative_regulation of Gene_expression of CCL2 1 0.14 0.09 0.16
99 INT100456 Binding of Gm694 and Ighd 1 0.00 0.78 0.16
100 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16
101 INT188569 Binding of CD4 and TLR4 1 0.16 0.34 0.16
102 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16
103 INT343848 Positive_regulation of TLR4 Positive_regulation of STAT1 1 0.17 0.16 0.15
104 INT231757 TLR4 Positive_regulation of Negative_regulation of HMOX1 1 0.26 1.37 0.15
105 INT278373 Myd88 Regulation of Phosphorylation of Syk 1 0.15 0.35 0.15
106 INT278394 Myd88 Regulation of Phosphorylation of Hps5 1 0.11 0.35 0.15
107 INT343835 TLR4 Positive_regulation of STAT1 1 0.17 0.11 0.15
108 INT343828 MMRN1 Positive_regulation of TLR4 1 0.02 0.91 0.14
109 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
110 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
111 INT285419 Positive_regulation of Binding of CD14 and TLR4 1 0.32 0.19 0.14
112 INT107647 Ighg1 Negative_regulation of Arigg4 1 0.01 0.5 0.14
113 INT43495 Cd74 Regulation of Gene_expression of Ifng 1 0.47 0 0.14
114 INT107645 Arigg4 Negative_regulation of Ighg1 1 0.01 0.5 0.14
115 INT343920 Binding of TLR4 and Hmgb1 1 0.39 0.97 0.13
116 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13
117 INT346501 MYD88 Positive_regulation of Nfkb1 1 0.01 0.5 0.13
118 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13
119 INT285421 Positive_regulation of Binding of TLR4 and LY96 1 0.17 0.18 0.13
120 INT342518 HSP90B1 Positive_regulation of Gene_expression of TLR4 1 0.04 0.4 0.13
121 INT87839 Binding of Cd74 and Dcn 1 0.36 0.21 0.13
122 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13
123 INT351144 Binding of Ighg2b and Ighg2a 1 0.00 0.78 0.12
124 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12
125 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12
126 INT150390 Binding of CD27 and MEFV 1 0.27 0.85 0.12
127 INT220633 Binding of Kat5 and Ighd 1 0.09 0.32 0.12
128 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
129 INT254201 Myd88 Positive_regulation of Ik 1 0.00 0.14 0.12
130 INT334870 Binding of C4b and Mpz 1 0.10 0 0.11
131 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11
132 INT334861 Positive_regulation of Binding of C4b and Mpz 1 0.13 0 0.11
133 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11
134 INT231768 Binding of HMOX1 and TLR4 1 0.23 0.95 0.11
135 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
136 INT337308 PTAFR Regulation of TLR4 1 0.24 0.1 0.1
137 INT343862 Binding of FN1 and TLR4 1 0.05 0.89 0.1
138 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1
139 INT294776 PAM Positive_regulation of TLR4 1 0.00 0.17 0.1
140 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1
141 INT343858 Binding of AKT1 and MYD88 1 0.02 0.26 0.1
142 INT311735 Binding of Plat and Fcgr2b 1 0.29 0.65 0.1
143 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
144 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1
145 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1
146 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09
147 INT185073 Bpifa2 Positive_regulation of Ighg1 1 0.27 0.93 0.09
148 INT350073 Binding of co and Myd88 1 0.00 0.17 0.08
149 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
150 INT254223 Tlr3 Positive_regulation of Myd88 1 0.16 0.23 0.08
151 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
152 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
153 INT306260 TLR4 Positive_regulation of TFAM 1 0.01 0 0.07
154 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06
155 INT332017 Binding of Ighm and Mbl1 1 0.11 0.26 0.06
156 INT318028 Binding of IRF6 and Tlr4 1 0.00 0.61 0.06
157 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06
158 INT350481 Tlr4 Positive_regulation of Gene_expression of Myd88 1 0.26 0.06 0.06
159 INT334868 Binding of C4b and Nfatc1 1 0.01 0 0.06
160 INT334260 Negative_regulation of Binding of Myd88 and Il1 1 0.01 0.4 0.06
161 INT334258 Binding of Myd88 and Irak4 2 0.26 0.24 0.05
162 INT115324 Binding of FCGR3A and Ighm 1 0.00 0.56 0.05
163 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05
164 INT231766 TLR4 Negative_regulation of Gene_expression of HMOX1 1 0.28 0.71 0.05
165 INT115323 Binding of GPI and Ighm 1 0.00 0.56 0.05
166 INT246413 TLR4 Regulation of TLR3 1 0.28 0.81 0.05
167 INT352087 Binding of ADAM11 and TLR4 1 0.05 1.09 0.04
168 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04
169 INT295477 Binding of TLR4 and LANCL1 1 0.01 0.16 0.04
170 INT315945 IgG Positive_regulation of Gene_expression of Ighm 1 0.13 0.56 0.04
171 INT350802 Binding of MYD88 and TLR3 1 0.01 0 0.04
172 INT334262 Myd88 Positive_regulation of Tlr7 1 0.05 0.3 0.04
173 INT231775 TLR4 Regulation of Gene_expression of HMOX1 1 0.29 0.68 0.04
174 INT352076 Binding of TLR4 and Positive_regulation of ADAM11 1 0.06 1.09 0.04
175 INT290163 Atp6v1e1 Positive_regulation of Ighm 1 0.12 0.26 0.04
176 INT238008 Myd88 Regulation of Hand1 1 0.03 0.82 0.04
177 INT231774 Gene_expression of TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
178 INT231762 TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
179 INT348820 Cd74 Regulation of Gene_expression of TFDP3 1 0.07 0.16 0.04
180 INT315943 Ighm Positive_regulation of Gene_expression of IgG 1 0.13 0.56 0.04
181 INT161533 Tlr4 Regulation of Gene_expression of Tlr4 1 0.01 0.75 0.03
182 INT290313 Binding of MYD88 and TLR7 1 0.03 0.1 0.03
183 INT334867 Binding of C4b and Sox10 1 0.04 0 0.03
184 INT235544 Binding of Ighm and Olr1 1 0.00 0.68 0.03
185 INT322876 Binding of PDCD10 and Inpp5d 1 0.03 0.46 0.03
186 INT334872 Positive_regulation of Binding of C4b and Sox10 1 0.04 0 0.03
187 INT161531 Nfkbia Regulation of Gene_expression of Tlr4 1 0.01 0.75 0.03
188 INT214547 Binding of CD27 and SLEB1 1 0.05 1.38 0.03
189 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03
190 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03
191 INT236078 Binding of AGER and HLA-DMA 1 0.08 0.81 0
192 INT337300 STAT3 Regulation of TLR4 1 0.15 0 0
193 INT320351 Pnp Regulation of Ighg2b 1 0.02 0.31 0
194 INT350077 Negative_regulation of Binding of Myd88 and Tlr4 1 0.12 0.16 0
195 INT215128 Ighm Regulation of Ighg1 1 0.12 0.27 0
196 INT242876 Negative_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
197 INT161829 IgG Negative_regulation of Igha 1 0.01 0.13 0
198 INT172118 Binding of HSPA1B and C4b 1 0.39 0.92 0
199 INT197761 Binding of KRT5 and C4a 1 0.02 2.29 0
200 INT348039 Binding of Myd88 and Irak2 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for immunoglobulin mediated immune response. They are ordered first by their pain relevance and then by number of times they were reported in immunoglobulin mediated immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
2 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
3 INT134651 Binding of TLR4 89 0.48 66.96 23.19
4 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
5 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92
6 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
7 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
8 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
9 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
10 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
11 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
12 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47
13 INT195 Gene_expression of C4a 16 0.48 15.55 6.1
14 INT97797 Localization of TLR4 18 0.77 13.78 6
15 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
16 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
17 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29
18 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
19 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01
20 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4
21 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
22 INT142754 Binding of Myd88 20 0.36 9.61 3.8
23 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
24 INT9223 Localization of Ighg1 22 0.78 11.03 3.67
25 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65
26 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
27 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47
28 INT187168 Binding of Cd74 13 0.27 11.2 3.44
29 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
30 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85
31 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
32 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8
33 INT79476 Gene_expression of HLA-DMA 23 0.38 9.5 2.76
34 INT243350 Binding of CD74 2 0.11 4.86 2.72
35 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48
36 INT49930 Binding of Ighg1 21 0.37 13.27 2.43
37 INT173504 Positive_regulation of Gene_expression of Ighg1 16 0.47 7.2 2.36
38 INT55897 Positive_regulation of C4a 8 0.29 3.81 2.07
39 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01
40 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
41 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
42 INT95904 Gene_expression of CD27 45 0.76 26.17 1.93
43 INT253975 Binding of Cd74 4 0.27 4.57 1.88
44 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
45 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86
46 INT20207 Binding of Ighm 14 0.46 2.88 1.79
47 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
48 INT56100 Negative_regulation of Gene_expression of Ighm 5 0.48 2.07 1.72
49 INT22058 Positive_regulation of Igha 7 0.49 5.29 1.69
50 INT233975 Positive_regulation of Gene_expression of Myd88 7 0.66 4.17 1.65
51 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
52 INT179548 Gene_expression of C4b 17 0.58 9.88 1.62
53 INT68250 Regulation of Gene_expression of Ighg1 7 0.40 2.99 1.56
54 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54
55 INT112013 Negative_regulation of Gene_expression of Ighg1 7 0.38 3.57 1.42
56 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
57 INT246928 Negative_regulation of Myd88 12 0.38 6.16 1.3
58 INT233970 Regulation of Myd88 7 0.45 5.2 1.28
59 INT68248 Transcription of Ighg1 3 0.61 3.02 1.25
60 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13
61 INT163914 Positive_regulation of Prkcd 1 0.67 1.43 1.12
62 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1
63 INT24868 Localization of Ighd 7 0.78 2.08 1.01
64 INT118738 Transcription of Tlr4 4 0.70 1.39 1
65 INT132177 Binding of CD27 3 0.19 1.84 1
66 INT171113 Binding of Ighg2b 3 0.47 2.85 0.96
67 INT138683 Regulation of Ighg1 15 0.30 7.95 0.94
68 INT145772 Regulation of C4a 3 0.38 1.99 0.92
69 INT122422 Negative_regulation of Phosphorylation of Ighm 1 0.01 0 0.91
70 INT184665 Positive_regulation of C4b 7 0.28 5.84 0.9
71 INT237858 Positive_regulation of MYD88 5 0.49 2.93 0.9
72 INT116058 Gene_expression of Cd74 2 0.56 0.55 0.89
73 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
74 INT250171 Localization of Myd88 4 0.72 1.95 0.88
75 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
76 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
77 INT120393 Negative_regulation of PRKCD 3 0.22 1.07 0.86
78 INT192404 Localization of Ighm 15 0.48 5.8 0.85
79 INT120396 Positive_regulation of Localization of PRKCD 1 0.26 0.42 0.85
80 INT122425 Phosphorylation of Ighm 1 0.01 0 0.85
81 INT166126 Gene_expression of MYD88 5 0.54 2.67 0.84
82 INT120392 Localization of PRKCD 1 0.39 0.4 0.83
83 INT254253 Transcription of Ighm 5 0.45 3.6 0.81
84 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81
85 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
86 INT184341 Negative_regulation of C4b 12 0.50 7.66 0.75
87 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
88 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
89 INT264973 Binding of MYD88 4 0.35 1.2 0.74
90 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
91 INT322032 Binding of TLR8 3 0.32 2.57 0.69
92 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
93 INT102655 Positive_regulation of Positive_regulation of Ighm 2 0.32 0.74 0.67
94 INT334226 Positive_regulation of Localization of Myd88 1 0.36 0.54 0.67
95 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
96 INT233973 Negative_regulation of Gene_expression of Myd88 4 0.38 1.32 0.61
97 INT116060 Negative_regulation of Gene_expression of Cd74 1 0.12 0 0.61
98 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
99 INT220110 Negative_regulation of Gene_expression of Ighd 1 0.13 2.55 0.57
100 INT3513 Negative_regulation of Igha 9 0.38 7.43 0.56
101 INT184049 Positive_regulation of Gene_expression of Ighg2b 2 0.40 1.54 0.53
102 INT264963 Positive_regulation of Binding of MYD88 1 0.17 0.18 0.52
103 INT271439 Positive_regulation of Localization of Cd74 1 0.36 1.01 0.52
104 INT179549 Positive_regulation of Gene_expression of C4b 2 0.19 1.36 0.49
105 INT203131 Regulation of Binding of Ighg2b 1 0.31 1.36 0.49
106 INT271435 Localization of Cd74 1 0.54 0.95 0.49
107 INT120390 Phosphorylation of PRKCD 1 0.33 0.38 0.49
108 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
109 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
110 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46
111 INT254172 Negative_regulation of Gene_expression of Cd74 1 0.24 1.03 0.44
112 INT68237 Positive_regulation of Transcription of Ighg1 1 0.44 0 0.43
113 INT120394 Positive_regulation of PRKCD 2 0.26 1.58 0.41
114 INT55898 Localization of C4a 2 0.40 1.29 0.41
115 INT187159 Negative_regulation of Binding of CD27 1 0.22 0.63 0.41
116 INT239036 Positive_regulation of HLA-DMA 4 0.67 1.44 0.4
117 INT246422 Transcription of MYD88 2 0.52 0.77 0.38
118 INT94933 Positive_regulation of Gene_expression of Bcl10 1 0.01 1.74 0.38
119 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37
120 INT220962 Positive_regulation of Localization of Ighg1 2 0.46 2.58 0.37
121 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
122 INT256056 Positive_regulation of Binding of Myd88 2 0.48 0.36 0.36
123 INT30049 Gene_expression of Bcl10 4 0.51 2.36 0.35
124 INT179545 Transcription of C4b 2 0.40 0.59 0.35
125 INT179541 Positive_regulation of Transcription of C4b 1 0.10 0.59 0.35
126 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
127 INT17050 Regulation of CD27 1 0.01 1.38 0.35
128 INT330616 Positive_regulation of Gene_expression of Inpp5d 2 0.49 0.89 0.34
129 INT120391 Negative_regulation of Localization of PRKCD 1 0.22 0 0.34
130 INT224714 Localization of Ighg2b 4 0.73 0.48 0.33
131 INT207897 Positive_regulation of TLR8 3 0.17 2.52 0.33
132 INT120398 Positive_regulation of Positive_regulation of PRKCD 1 0.26 0 0.33
133 INT203076 Positive_regulation of Positive_regulation of Myd88 1 0.19 0.65 0.32
134 INT203072 Positive_regulation of Myd88 1 0.19 0.65 0.32
135 INT330615 Gene_expression of Inpp5d 2 0.66 0.78 0.31
136 INT100455 Binding of Ighd 1 0.37 1.61 0.31
137 INT323835 Negative_regulation of Binding of Ighg1 1 0.23 0.67 0.31
138 INT323834 Regulation of Binding of Ighg1 1 0.24 0.69 0.31
139 INT192406 Regulation of Ighm 16 0.31 5.58 0.29
140 INT237066 Positive_regulation of Irf7 6 0.54 3.56 0.29
141 INT36594 Binding of C4a 4 0.09 2.29 0.29
142 INT334853 Phosphorylation of C4b 1 0.22 0 0.29
143 INT215118 Negative_regulation of Ighg2b 2 0.30 0.93 0.28
144 INT79959 Positive_regulation of Positive_regulation of C4a 1 0.05 0.34 0.28
145 INT3912 Localization of HLA-DMA 2 0.35 1.09 0.27
146 INT86183 Binding of Igha 2 0.47 1.5 0.27
147 INT197492 Regulation of Gene_expression of Myd88 2 0.39 1.95 0.27
148 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
149 INT207896 Gene_expression of TLR8 3 0.36 2.82 0.26
150 INT57545 Positive_regulation of Positive_regulation of Ighd 1 0.15 1.78 0.24
151 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
152 INT220890 Localization of C4b 2 0.64 0.46 0.22
153 INT55900 Negative_regulation of Localization of C4a 1 0.22 0.33 0.22
154 INT330612 Positive_regulation of Localization of Inpp5d 1 0.02 0.35 0.22
155 INT330610 Localization of Inpp5d 1 0.02 0.3 0.22
156 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
157 INT214569 Positive_regulation of Localization of CD27 3 0.49 2.16 0.19
158 INT242901 Regulation of Gene_expression of MYD88 2 0.18 0.19 0.19
159 INT242897 Positive_regulation of Gene_expression of MYD88 2 0.20 0.27 0.19
160 INT347641 Regulation of Positive_regulation of Inpp5d 1 0.27 0.33 0.19
161 INT163189 Localization of CD27 7 0.74 5.31 0.18
162 INT347643 Positive_regulation of Inpp5d 1 0.46 0.33 0.18
163 INT221116 Regulation of HLA-DMA 4 0.05 0.7 0.17
164 INT233971 Transcription of Myd88 2 0.60 1.01 0.17
165 INT214566 Positive_regulation of CD27 1 0.68 13.39 0.17
166 INT291908 Negative_regulation of HLA-DMA 1 0.08 0.14 0.17
167 INT238679 Negative_regulation of Localization of Ighg1 2 0.39 0.61 0.15
168 INT129994 Positive_regulation of Protein_catabolism of Igha 1 0.11 1.16 0.15
169 INT317803 Negative_regulation of Ighg2a 1 0.02 0.71 0.15
170 INT129993 Protein_catabolism of Igha 1 0.20 1.16 0.15
171 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
172 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
173 INT317802 Regulation of Ighg2a 1 0.01 0.49 0.14
174 INT317804 Regulation of Gene_expression of Ighg2a 1 0.01 0.5 0.14
175 INT79958 Negative_regulation of Positive_regulation of C4a 1 0.04 0.17 0.14
176 INT276623 Negative_regulation of Binding of Ighm 1 0.32 0.12 0.14
177 INT24794 Regulation of Igha 1 0.00 0.09 0.14
178 INT172104 Binding of C4b 4 0.41 3.89 0.13
179 INT79960 Regulation of Positive_regulation of C4a 1 0.05 0.17 0.13
180 INT317801 Gene_expression of Ighg2a 1 0.03 0.49 0.13
181 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
182 INT311718 Positive_regulation of Fcgr2b 1 0.30 0.68 0.12
183 INT334237 Negative_regulation of Binding of Myd88 1 0.30 1.16 0.12
184 INT131015 Negative_regulation of Cd74 1 0.17 0.25 0.12
185 INT306310 Positive_regulation of Positive_regulation of Myd88 1 0.38 0.41 0.12
186 INT209698 Gene_expression of PRKCD 1 0.33 1.78 0.12
187 INT242898 Regulation of MYD88 2 0.33 0.88 0.11
188 INT17473 Negative_regulation of Ighd 1 0.08 0.42 0.11
189 INT329055 Gene_expression of Myd88 1 0.72 1.18 0.11
190 INT71097 Localization of Igha 2 0.73 0.27 0.1
191 INT303410 Regulation of Ighg2b 2 0.25 1.22 0.09
192 INT303412 Positive_regulation of Regulation of Ighg2b 2 0.43 1.23 0.09
193 INT107642 Positive_regulation of Positive_regulation of Ighg1 2 0.30 1.35 0.08
194 INT291910 Positive_regulation of Gene_expression of HLA-DMA 1 0.10 0.06 0.08
195 INT209688 Negative_regulation of Positive_regulation of PRKCD 1 0.18 1.1 0.08
196 INT334227 Positive_regulation of Regulation of Myd88 1 0.36 0.63 0.08
197 INT220889 Negative_regulation of Binding of C4b 1 0.36 0.53 0.07
198 INT214554 Positive_regulation of Positive_regulation of CD27 1 0.49 3.37 0.07
199 INT329054 Negative_regulation of Gene_expression of Myd88 1 0.54 0.13 0.06
200 INT254170 Positive_regulation of Positive_regulation of Irf7 1 0.10 0.17 0.06
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