GO:0016080

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Name synaptic vesicle targeting
Categary Process
Go Slim No
Go Link GO:0016080
Unique Molecular Interactions 48
Total Molecular Interactions 62
Total Single Events 803
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic vesicle targeting. They are ordered first by their pain relevance and then by number of times they were reported for synaptic vesicle targeting. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
2 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
3 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
4 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
5 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2
6 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13
7 INT253328 Binding of IL8 and Scrib 1 0.04 0.79 0.12
8 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
9 INT351426 SEPT5 Regulation of HRAS 1 0.00 0.7 0.09
10 INT351425 HRAS Regulation of SEPT5 1 0.00 0.7 0.09
11 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
12 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
13 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
14 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
15 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
16 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
17 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
18 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
19 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
20 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
21 INT337677 Scrib Positive_regulation of Gene_expression of MMP9 1 0.03 1.12 0
22 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
23 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
24 INT307804 Ace Positive_regulation of Gene_expression of Scrib 1 0.21 2.43 0
25 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0
26 INT218259 Binding of CRP and SEPT5 1 0.04 0.33 0
27 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0
28 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
29 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
30 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
31 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
32 INT337678 Scrib Positive_regulation of MMP7 1 0.03 1.11 0
33 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
34 INT337681 Scrib Positive_regulation of MMP9 1 0.01 1.12 0
35 INT189548 Binding of SEPT5 and VWF 1 0.01 0.27 0
36 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
37 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
38 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
39 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0
40 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
41 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
42 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
43 INT326164 Binding of S100A2 and Scrib 1 0.01 1.16 0
44 INT283343 Binding of Srr and Pclo 1 0.05 0 0
45 INT337679 Binding of MSI1 and Scrib 1 0.00 1.61 0
46 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
47 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic vesicle targeting. They are ordered first by their pain relevance and then by number of times they were reported in synaptic vesicle targeting. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
2 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
3 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
4 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
5 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
6 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
7 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81
8 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66
9 INT163544 Binding of Psen1 40 0.36 15.28 2.42
10 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
11 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
12 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
13 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
14 INT254072 Gene_expression of SEPT5 23 0.16 8.29 1.43
15 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39
16 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
17 INT190031 Binding of Scrib 19 0.36 21.9 1.01
18 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
19 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
20 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
21 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
22 INT214067 Regulation of Scrib 11 0.20 12.48 0.45
23 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
24 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
25 INT193856 Localization of Psen1 19 0.73 9.79 0.41
26 INT36781 Binding of Pclo 1 0.23 0 0.39
27 INT190017 Localization of Scrib 6 0.10 7 0.38
28 INT108326 Positive_regulation of Gene_expression of Scrib 5 0.26 9.02 0.36
29 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
30 INT267831 Negative_regulation of Positive_regulation of Scrib 1 0.04 1.56 0.31
31 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
32 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
33 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
34 INT261542 Localization of SEPT5 2 0.17 0.06 0.2
35 INT261553 Positive_regulation of Localization of SEPT5 1 0.11 0.06 0.2
36 INT267829 Regulation of Gene_expression of Scrib 2 0.20 5.89 0.19
37 INT267830 Regulation of Negative_regulation of Scrib 1 0.04 0.95 0.19
38 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
39 INT253320 Positive_regulation of Positive_regulation of Scrib 1 0.05 0.4 0.14
40 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
41 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
42 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
43 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
44 INT253323 Negative_regulation of Binding of Scrib 1 0.05 0.82 0.09
45 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
46 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
47 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
48 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
49 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
50 INT296753 Protein_catabolism of Scrib 1 0.05 0.73 0.07
51 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
52 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
53 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
54 INT260210 Positive_regulation of SEPT5 2 0.23 1.42 0.04
55 INT272454 Positive_regulation of Gene_expression of SEPT5 1 0.02 0.65 0.04
56 INT283320 Localization of Pclo 1 0.14 0 0.03
57 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
58 INT272452 Transcription of SEPT5 1 0.03 0.65 0
59 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
60 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
61 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
62 INT190036 Positive_regulation of Localization of Scrib 1 0.04 0.83 0
63 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
64 INT218262 Binding of SEPT5 1 0.04 0.33 0
65 INT177774 Transcription of PSEN1 1 0.33 0.09 0
66 INT283321 Gene_expression of Pclo 1 0.12 0 0
67 INT307791 Negative_regulation of Gene_expression of Scrib 1 0.19 2.55 0
68 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
69 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
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