GO:0016126

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Name sterol biosynthetic process
Categary Process
Go Slim No
Go Link GO:0016126
Unique Molecular Interactions 69
Total Molecular Interactions 86
Total Single Events 316
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for sterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41
2 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7
3 INT77379 Tmie Negative_regulation of Ebp 1 0.03 0 0.59
4 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
5 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
6 INT37270 Negative_regulation of Ebp Positive_regulation of LH 1 0.37 0 0.38
7 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35
8 INT299557 Binding of CRS and SQLE 1 0.00 0.7 0.29
9 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
10 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24
11 INT261394 Nsdhl Negative_regulation of nt 1 0.01 1.69 0.24
12 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
13 INT186957 Nsdhl Positive_regulation of Tmed4 1 0.04 0.71 0.23
14 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
15 INT299592 SQLE Regulation of RatNP-3b 1 0.01 0.99 0.22
16 INT261373 Nsdhl Positive_regulation of Gene_expression of Gfap 1 0.10 2.05 0.19
17 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
18 INT186954 Binding of Des and Nsdhl 1 0.06 0.32 0.16
19 INT261384 Nsdhl Negative_regulation of Gene_expression of Mbp 1 0.01 1.43 0.14
20 INT261381 Nsdhl Regulation of Gene_expression of S100b 1 0.06 0.82 0.13
21 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
22 INT261390 Binding of Nsdhl and Bdnf 1 0.05 1.33 0.12
23 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
24 INT261380 Nsdhl Negative_regulation of P4hb 1 0.02 1.36 0.11
25 INT261379 Nsdhl Positive_regulation of Thra 1 0.07 1.12 0.11
26 INT261391 Binding of Nsdhl and P4hb 1 0.02 1.3 0.1
27 INT204898 Negative_regulation of Tlr4 Negative_regulation of Ch25h 1 0.21 0.09 0.09
28 INT204894 Tlr4 Positive_regulation of Ch25h 1 0.23 0.09 0.09
29 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
30 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09
31 INT261371 Nsdhl Negative_regulation of Positive_regulation of Bdnf 1 0.06 1.18 0.09
32 INT261376 Nsdhl Positive_regulation of Gene_expression of Nrgn 1 0.06 0.86 0.08
33 INT261386 Nsdhl Positive_regulation of Map2 1 0.08 0.59 0.07
34 INT261395 Nsdhl Positive_regulation of Syn1 1 0.00 0.59 0.07
35 INT261392 Binding of Nsdhl and Syn1 1 0.00 0.65 0.07
36 INT204896 Tlr4 Negative_regulation of Ch25h 1 0.21 0.09 0.07
37 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07
38 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
39 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
40 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05
41 INT261385 LH Regulation of Localization of Nsdhl 1 0.02 0.65 0.05
42 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
43 INT261382 Nsdhl Regulation of Il6 1 0.03 0.66 0.04
44 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
45 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
46 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
47 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
48 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
49 INT299556 SQLE Regulation of CRS 1 0.00 0.77 0.03
50 INT261383 Nsdhl Positive_regulation of Gene_expression of Il4 1 0.03 0.46 0.03
51 INT186960 Positive_regulation of Nsdhl Positive_regulation of Tmed4 1 0.03 0.05 0.03
52 INT301243 Mir29a Positive_regulation of Mvd 1 0.03 1.66 0
53 INT262203 Nr1i2 Positive_regulation of Gene_expression of Hmgcs2 1 0.23 0.22 0
54 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0
55 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0
56 INT301242 Mvd Positive_regulation of Gene_expression of Mir29a 1 0.04 0.1 0
57 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0
58 INT246533 Fdft1 Positive_regulation of Gene_expression of Gstp2 1 0.01 1.57 0
59 INT262156 Nr1i2 Negative_regulation of Gene_expression of Hmgcs2 1 0.22 0.22 0
60 INT268396 Binding of BRAF and Ebp 1 0.01 1.72 0
61 INT190051 Binding of Ebp and Mrc1 1 0.04 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in sterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58
2 INT7978 Positive_regulation of Nsdhl 9 0.43 5.6 2.63
3 INT61907 Negative_regulation of Ebp 9 0.37 4.77 2.49
4 INT177778 Gene_expression of SQLE 28 0.40 16.42 2.08
5 INT97073 Positive_regulation of Ebp 6 0.42 2.68 1.8
6 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
7 INT156804 Transcription of Ebp 1 0.41 0.49 1.13
8 INT156805 Gene_expression of Ebp 6 0.40 6.09 1.07
9 INT167 Regulation of Ebp 3 0.44 0.77 1.03
10 INT176063 Positive_regulation of SQLE 4 0.36 4.28 1
11 INT1011 Positive_regulation of Ebp 3 0.50 1.59 0.86
12 INT77375 Phosphorylation of Ebp 1 0.13 0 0.81
13 INT186941 Localization of Nsdhl 2 0.46 2.7 0.74
14 INT171878 Binding of SQLE 8 0.04 4 0.63
15 INT158440 Negative_regulation of Nsdhl 4 0.21 3.22 0.51
16 INT147919 Regulation of Ebp 1 0.08 0.94 0.48
17 INT256628 Regulation of Nsdhl 2 0.11 4.12 0.43
18 INT261353 Negative_regulation of Gene_expression of Nsdhl 1 0.17 0.71 0.43
19 INT147918 Positive_regulation of Negative_regulation of Ebp 1 0.14 0.88 0.42
20 INT7979 Binding of Nsdhl 6 0.30 3.71 0.4
21 INT84110 Negative_regulation of Ebp 5 0.42 0.32 0.35
22 INT212761 Regulation of SQLE 2 0.23 1.21 0.35
23 INT186939 Positive_regulation of Positive_regulation of Nsdhl 2 0.31 0.86 0.34
24 INT191601 Negative_regulation of Fdft1 2 0.04 2.13 0.33
25 INT281177 Regulation of Insig1 2 0.25 0.93 0.33
26 INT299574 Localization of SQLE 1 0.10 1.41 0.32
27 INT297865 Positive_regulation of Gene_expression of Insig1 2 0.21 0.4 0.28
28 INT84109 Binding of Ebp 2 0.34 0.27 0.23
29 INT262077 Positive_regulation of Insig1 3 0.29 0.34 0.21
30 INT270625 Regulation of Gene_expression of Insig1 2 0.19 1.4 0.21
31 INT297868 Regulation of Regulation of Insig1 1 0.11 0.82 0.21
32 INT150306 Negative_regulation of Positive_regulation of Ebp 1 0.15 0.07 0.2
33 INT204862 Gene_expression of Ch25h 1 0.47 0.48 0.18
34 INT206915 Regulation of Gene_expression of Nsdhl 2 0.22 1 0.13
35 INT339163 Negative_regulation of Positive_regulation of SQLE 1 0.22 0.26 0.13
36 INT315005 Binding of Hmgcs2 1 0.11 0.73 0.11
37 INT246532 Positive_regulation of Fdft1 1 0.01 3.85 0.11
38 INT191645 Regulation of Fdft1 1 0.01 0.29 0.11
39 INT206912 Positive_regulation of Gene_expression of Nsdhl 2 0.25 1.59 0.09
40 INT204831 Positive_regulation of Ch25h 1 0.13 0.09 0.09
41 INT226027 Positive_regulation of Gene_expression of Ebp 1 0.13 2.46 0.06
42 INT287201 Transcription of Insig1 2 0.29 2.87 0.05
43 INT246531 Gene_expression of Fdft1 1 0.01 3.08 0.05
44 INT177775 Negative_regulation of SQLE 7 0.06 5.97 0.04
45 INT190030 Binding of Ebp 1 0.09 0.72 0.03
46 INT204826 Negative_regulation of Ch25h 1 0.26 0.06 0.03
47 INT200791 Binding of Mvd 1 0.13 1.5 0.03
48 INT204828 Localization of Ch25h 1 0.45 0.06 0.03
49 INT200788 Positive_regulation of Mvd 2 0.17 1.55 0
50 INT262066 Positive_regulation of Transcription of Hmgcs2 1 0.23 0.12 0
51 INT262058 Gene_expression of Hmgcs2 1 0.28 0.21 0
52 INT206914 Regulation of Localization of Nsdhl 1 0.22 0.46 0
53 INT169262 Negative_regulation of Binding of Ebp 1 0.39 0 0
54 INT262064 Negative_regulation of Positive_regulation of Insig1 1 0.09 0.05 0
55 INT299573 Regulation of Gene_expression of SQLE 1 0.05 0.21 0
56 INT339172 Transcription of SQLE 1 0.43 0.91 0
57 INT262110 Negative_regulation of Hmgcs2 1 0.20 0.09 0
58 INT339211 Positive_regulation of Gene_expression of SQLE 1 0.26 0.91 0
59 INT186936 Transcription of Nsdhl 1 0.42 0.11 0
60 INT301210 Gene_expression of Mvd 1 0.19 1.48 0
61 INT262101 Transcription of Hmgcs2 1 0.32 0.21 0
62 INT297864 Positive_regulation of Transcription of Insig1 1 0.21 2.31 0
63 INT257565 Negative_regulation of Gene_expression of SQLE 1 0.06 1.16 0
64 INT301206 Negative_regulation of Gene_expression of Mvd 1 0.12 0.1 0
65 INT115692 Negative_regulation of Binding of Nsdhl 1 0.36 0 0
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