GO:0016176

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Name superoxide-generating NADPH oxidase activator activity
Categary Function
Go Slim No
Go Link GO:0016176
Unique Molecular Interactions 41
Total Molecular Interactions 49
Total Single Events 335
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for superoxide-generating NADPH oxidase activator activity. They are ordered first by their pain relevance and then by number of times they were reported for superoxide-generating NADPH oxidase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
2 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
3 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
4 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
5 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
6 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
7 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
8 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
9 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
10 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
11 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
12 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
13 INT225024 PDGFB Positive_regulation of Gene_expression of Cxcl5 1 0.16 0.08 0.13
14 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
15 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
16 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
17 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
18 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
19 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
20 INT94852 PDGFB Regulation of Gene_expression of COL7A1 1 0.09 0.06 0.06
21 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
22 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
23 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
24 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
25 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
26 INT279288 PDGFB Positive_regulation of NCOR2 1 0.00 0.52 0.03
27 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
28 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03
29 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03
30 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
31 INT328411 Nlrp1a Negative_regulation of Pdgfb 1 0.08 0.39 0
32 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
33 INT223083 Gene_expression of Pdgfb Positive_regulation of Cm3 1 0.02 1 0
34 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0
35 INT212083 Binding of SSRP1 and NOXO1 1 0.02 0.67 0
36 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for superoxide-generating NADPH oxidase activator activity. They are ordered first by their pain relevance and then by number of times they were reported in superoxide-generating NADPH oxidase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
2 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
3 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
4 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
5 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
6 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
7 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
8 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
9 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
10 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
11 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
12 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
13 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
14 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
15 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
16 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
17 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
18 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
19 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
20 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
21 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
22 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
23 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
24 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
25 INT349702 Positive_regulation of Transcription of Pdgfb 1 0.35 0 0.23
26 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22
27 INT349701 Transcription of Pdgfb 1 0.40 0 0.22
28 INT212089 Gene_expression of NOXO1 4 0.10 2.05 0.21
29 INT225004 Regulation of Positive_regulation of PDGFB 1 0.26 0.1 0.13
30 INT319408 Negative_regulation of Binding of PDGFB 1 0.15 0.89 0.09
31 INT355724 Negative_regulation of Positive_regulation of Pdgfb 1 0.13 0.6 0.07
32 INT319411 Negative_regulation of Transcription of PDGFB 1 0.15 1.03 0.07
33 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05
34 INT225003 Positive_regulation of Binding of PDGFB 1 0.29 0 0.03
35 INT202308 Phosphorylation of PDGFB 1 0.34 0.43 0.03
36 INT212098 Positive_regulation of NOXO1 1 0.06 0.88 0
37 INT212099 Negative_regulation of Gene_expression of NOXO1 1 0.05 0.76 0
38 INT223077 Regulation of Pdgfb 1 0.23 0.34 0
39 INT343453 Phosphorylation of Pdgfb 1 0.13 0.1 0
40 INT277700 Binding of Pdgfb 1 0.09 0.67 0
41 INT212087 Negative_regulation of NOXO1 1 0.05 0.47 0
42 INT277696 Regulation of Positive_regulation of Pdgfb 1 0.03 0.52 0
43 INT223079 Regulation of Gene_expression of Pdgfb 1 0.23 1.17 0
44 INT212097 Regulation of Gene_expression of NOXO1 1 0.06 0.71 0
45 INT256230 Positive_regulation of Gene_expression of NOXO1 1 0.09 0.75 0
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