GO:0016208

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Name AMP binding
Categary Function
Go Slim No
Go Link GO:0016208
Unique Molecular Interactions 83
Total Molecular Interactions 115
Total Single Events 500
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for AMP binding. They are ordered first by their pain relevance and then by number of times they were reported for AMP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
2 INT226128 Positive_regulation of Ghrl Regulation of Prkag1 1 0.06 0.28 0.97
3 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
4 INT84861 Rps6ka3 Positive_regulation of Transcription of APRT 1 0.28 0.19 0.55
5 INT226126 Negative_regulation of Ghrl Regulation of Prkag1 1 0.06 0.17 0.45
6 INT253145 Il6 Positive_regulation of Prkag1 1 0.11 0.73 0.44
7 INT226127 Regulation of Ghrl Regulation of Prkag1 1 0.05 0.07 0.42
8 INT226129 Ghrl Regulation of Localization of Prkag1 1 0.05 0.07 0.4
9 INT187521 ATIC Positive_regulation of Prkag1 1 0.01 1.07 0.37
10 INT226120 Cnr1 Positive_regulation of Prkag1 1 0.09 0 0.35
11 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
12 INT135891 S1pr1 Regulation of Prps1 1 0.01 0.15 0.33
13 INT226124 Ghrl Positive_regulation of Prkag1 1 0.06 0.24 0.33
14 INT187518 Positive_regulation of ATIC Positive_regulation of Prkag1 1 0.01 0.99 0.25
15 INT187485 Trib3 Positive_regulation of Prkag1 1 0.00 0.97 0.22
16 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
17 INT226123 Cnr1 Regulation of Prkag1 1 0.05 0.09 0.18
18 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
19 INT226130 Binding of Cnr1 and Prkag1 1 0.06 0 0.13
20 INT226132 Ghrl Positive_regulation of Gene_expression of Prkag1 1 0.06 0 0.12
21 INT226131 Mastl Positive_regulation of Gene_expression of Prkag1 1 0.01 0 0.12
22 INT253124 Ins1 Negative_regulation of Positive_regulation of Prkag1 1 0.02 0.12 0.1
23 INT317403 Negative_regulation of Binding of Prkag1 and Amp1 1 0.03 0.35 0.1
24 INT317401 Binding of Prkag1 and Amp1 1 0.03 0.35 0.1
25 INT317402 Positive_regulation of Amp1 Positive_regulation of Prkag1 1 0.03 0.27 0.09
26 INT305274 Obsty1 Regulation of Gene_expression of Prkag1 1 0.01 0.94 0.08
27 INT157263 PPARA Positive_regulation of APRT 1 0.54 0.92 0.08
28 INT253150 Il6 Positive_regulation of Phosphorylation of Prkag1 1 0.08 0.34 0.07
29 INT317390 Amp1 Positive_regulation of Phosphorylation of Prkag1 1 0.03 0.22 0.07
30 INT157272 Adipor1 Positive_regulation of APRT 1 0.12 0.88 0.07
31 INT329225 Prkag1 Positive_regulation of Akt1 1 0.09 1.27 0.07
32 INT317387 Amp1 Positive_regulation of Prkag1 1 0.04 0.34 0.07
33 INT353489 Negative_regulation of Aldh2 Negative_regulation of Prkag1 1 0.00 0.84 0.07
34 INT317389 Binding of Prkag1 and Stk11 1 0.16 0.2 0.06
35 INT317397 Negative_regulation of Binding of Prkag1 and Stk11 1 0.19 0.2 0.06
36 INT329218 Phosphorylation of Ppara Positive_regulation of Prkag1 1 0.34 0.2 0.05
37 INT253143 Regulation of Il6 Positive_regulation of Prkag1 1 0.07 0.08 0.05
38 INT253149 Regulation of Ins1 Positive_regulation of Prkag1 1 0.03 0.08 0.05
39 INT329216 Prkag1 Regulation of Mtor 1 0.01 0.35 0.04
40 INT253133 Ins1 Positive_regulation of Prkag1 1 0.04 0.08 0.04
41 INT329223 Prkag1 Regulation of Rps6kb1 1 0.14 0.35 0.04
42 INT187520 ATIC Positive_regulation of Phosphorylation of Prkag1 1 0.01 0 0.03
43 INT317388 Stk11 Regulation of Positive_regulation of Prkag1 1 0.23 0.11 0.03
44 INT311144 CAT Positive_regulation of APRT 1 0.01 0 0.03
45 INT317400 Acc Positive_regulation of Prkag1 1 0.29 0.06 0.03
46 INT336107 Negative_regulation of Prkag1 Negative_regulation of Phosphorylation of Mapk14 1 0.02 0.27 0
47 INT308747 Binding of Cftr and Prkag1 1 0.02 0 0
48 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
49 INT291111 Positive_regulation of PYGM Regulation of PDP1 1 0.02 0 0
50 INT311145 CAT Positive_regulation of Protein_catabolism of APRT 1 0.01 0 0
51 INT291098 PYGM Positive_regulation of PDK4 1 0.02 0 0
52 INT351980 Agt Positive_regulation of Phosphorylation of Prkag1 1 0.03 0.74 0
53 INT195062 PTHLH Positive_regulation of Gene_expression of Pygm 1 0.00 0.67 0
54 INT329215 Prkag1 Negative_regulation of Acaca 1 0.08 0.26 0
55 INT291112 PYGM Positive_regulation of Gene_expression of PDK4 1 0.02 0 0
56 INT291104 PYGM Regulation of Gene_expression of PDK4 1 0.01 0 0
57 INT309975 Binding of Pygm and Pkp2 1 0.01 0.4 0
58 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
59 INT309976 Binding of Pygm and Dsp 1 0.00 0.1 0
60 INT351623 APRT Positive_regulation of Pfkm 1 0.00 0.15 0
61 INT317396 Binding of Car2 and Prkag1 1 0.07 0.31 0
62 INT291110 PYGM Positive_regulation of Transcription of PDK4 1 0.02 0 0
63 INT309977 Pygm Positive_regulation of Localization of Pkp2 1 0.01 0.19 0
64 INT305263 Obsty1 Regulation of Phosphorylation of Prkag1 1 0.01 0.78 0
65 INT329224 Prkag1 Positive_regulation of Localization of Ins1 1 0.03 1.14 0
66 INT289520 Lep Regulation of Prkag1 1 0.00 0.08 0
67 INT151589 Stk11 Positive_regulation of Prkag1 1 0.41 0.17 0
68 INT351614 APRT Positive_regulation of MTAP 1 0.00 0.22 0
69 INT336108 Mapk14 Positive_regulation of Gene_expression of Prkag1 1 0.03 0.26 0
70 INT305260 Obsty1 Regulation of Prkag1 1 0.01 0.78 0
71 INT291109 PYGM Regulation of PDP1 1 0.02 0 0
72 INT329221 Prkag1 Negative_regulation of Hmgcr 1 0.06 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for AMP binding. They are ordered first by their pain relevance and then by number of times they were reported in AMP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121608 Positive_regulation of Prkag1 23 0.15 9.35 4.64
2 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89
3 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34
4 INT137549 Gene_expression of Pygm 12 0.05 6.74 3.16
5 INT11202 Positive_regulation of Pfkm 8 0.57 1.74 3.06
6 INT41545 Negative_regulation of APRT 8 0.57 2.99 2.88
7 INT35465 Negative_regulation of Pfkm 8 0.57 3.84 2.6
8 INT11201 Gene_expression of Pfkm 3 0.18 0.43 2.33
9 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13
10 INT162669 Regulation of Prkag1 4 0.09 3.77 2.1
11 INT37649 Gene_expression of Fbp1 4 0.49 3.16 1.84
12 INT26416 Regulation of APRT 2 0.44 0.67 1.74
13 INT162670 Gene_expression of Prkag1 5 0.22 4.45 1.73
14 INT38931 Localization of APRT 3 0.78 0.87 1.7
15 INT104015 Regulation of Gene_expression of Pfkm 1 0.01 0 1.54
16 INT151588 Phosphorylation of Prkag1 48 0.73 15.62 1.38
17 INT37203 Negative_regulation of Pygm 3 0.06 1.64 1.33
18 INT137548 Positive_regulation of Pygm 2 0.04 2.26 1.2
19 INT226111 Gene_expression of Prkag1 24 0.45 9.76 1.05
20 INT37648 Protein_catabolism of Fbp1 2 0.54 1.5 0.97
21 INT43145 Regulation of Regulation of Pfkm 1 0.45 0 0.97
22 INT14402 Positive_regulation of Fbp1 4 0.38 2.11 0.93
23 INT137551 Regulation of Pygm 2 0.01 1.59 0.87
24 INT151583 Regulation of Prkag1 11 0.21 3.68 0.85
25 INT132912 Phosphorylation of APRT 2 0.61 0.63 0.84
26 INT195056 Positive_regulation of Gene_expression of Pygm 2 0.04 1.99 0.83
27 INT121603 Positive_regulation of Positive_regulation of Prkag1 3 0.08 0.22 0.78
28 INT37650 Negative_regulation of Fbp1 1 0.55 1.24 0.77
29 INT132914 Positive_regulation of Phosphorylation of APRT 1 0.45 0 0.75
30 INT137550 Negative_regulation of Gene_expression of Pygm 3 0.03 1.72 0.71
31 INT151584 Negative_regulation of Prkag1 10 0.38 1.72 0.67
32 INT121607 Transcription of Prkag1 1 0.04 0.08 0.64
33 INT106573 Phosphorylation of Pfkm 1 0.43 0.1 0.64
34 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6
35 INT84859 Transcription of APRT 1 0.69 0.19 0.55
36 INT84860 Negative_regulation of Transcription of APRT 1 0.42 0.19 0.55
37 INT200072 Gene_expression of APRT 8 0.65 1 0.54
38 INT226109 Localization of Prkag1 3 0.43 1.89 0.44
39 INT20856 Binding of APRT 2 0.36 0 0.34
40 INT76999 Regulation of Fbp1 1 0.17 0.58 0.34
41 INT135888 Gene_expression of Prps1 1 0.03 0.21 0.34
42 INT317357 Binding of Prkag1 2 0.25 3.23 0.3
43 INT187496 Binding of Prkag1 1 0.04 0.93 0.27
44 INT187507 Phosphorylation of Prkag1 8 0.11 1.92 0.26
45 INT187501 Positive_regulation of Phosphorylation of Prkag1 1 0.06 0.59 0.26
46 INT261265 Gene_expression of PYGM 2 0.17 1.96 0.24
47 INT14401 Binding of Fbp1 2 0.31 2.24 0.22
48 INT311146 Protein_catabolism of APRT 1 0.01 0.39 0.2
49 INT35464 Positive_regulation of Positive_regulation of Pfkm 1 0.38 0.71 0.19
50 INT151580 Negative_regulation of Phosphorylation of Prkag1 7 0.33 3.45 0.18
51 INT11199 Positive_regulation of Gene_expression of Pfkm 1 0.12 0 0.15
52 INT253110 Positive_regulation of Positive_regulation of Prkag1 5 0.28 0.78 0.14
53 INT330011 Positive_regulation of Gene_expression of APRT 1 0.02 0 0.12
54 INT151581 Positive_regulation of Phosphorylation of Prkag1 6 0.61 1.97 0.11
55 INT258071 Positive_regulation of Negative_regulation of APRT 1 0.02 1.19 0.11
56 INT187500 Positive_regulation of Gene_expression of Prkag1 1 0.06 0.09 0.11
57 INT353488 Negative_regulation of Prkag1 1 0.01 0.92 0.1
58 INT300679 Binding of Cyb5r3 1 0.04 0.69 0.08
59 INT300682 Phosphorylation of Cyb5r3 1 0.07 0.37 0.08
60 INT305234 Regulation of Phosphorylation of Prkag1 2 0.30 1.07 0.04
61 INT305245 Negative_regulation of Gene_expression of Prkag1 2 0.21 0.95 0
62 INT309942 Binding of Pygm 1 0.01 0.12 0
63 INT305225 Positive_regulation of Gene_expression of Prkag1 1 0.05 0.8 0
64 INT291117 Negative_regulation of Gene_expression of PYGM 1 0.02 0.07 0
65 INT291128 Binding of PYGM 1 0.02 0.09 0
66 INT291140 Transcription of PYGM 1 0.03 0.23 0
67 INT291138 Positive_regulation of Gene_expression of PYGM 1 0.02 0 0
68 INT291122 Positive_regulation of Transcription of PYGM 1 0.02 0 0
69 INT291125 Regulation of Binding of PYGM 1 0.02 0.09 0
70 INT300677 Transcription of Cyb5r3 1 0.08 0.1 0
71 INT300680 Positive_regulation of Positive_regulation of Cyb5r3 1 0.05 0 0
72 INT291124 Regulation of PYGM 1 0.02 0.14 0
73 INT311147 Positive_regulation of Protein_catabolism of APRT 1 0.01 0.07 0
74 INT305243 Regulation of Gene_expression of Prkag1 1 0.03 0.91 0
75 INT300681 Positive_regulation of Transcription of Cyb5r3 1 0.06 0.1 0
76 INT309944 Localization of Pygm 1 0.01 0.15 0
77 INT329205 Negative_regulation of Positive_regulation of Prkag1 1 0.25 1.17 0
78 INT300678 Positive_regulation of Cyb5r3 1 0.08 0.32 0
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