GO:0016226

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Name iron-sulfur cluster assembly
Categary Process
Go Slim No
Go Link GO:0016226
Unique Molecular Interactions 48
Total Molecular Interactions 60
Total Single Events 1332
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for iron-sulfur cluster assembly. They are ordered first by their pain relevance and then by number of times they were reported for iron-sulfur cluster assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT27775 Binding of LH and Tst 1 0.25 0 0.93
2 INT122838 Mdh1 Positive_regulation of Tst 1 0.78 0.4 0.55
3 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
4 INT254578 Binding of TNF and Tst 1 0.02 1.57 0.13
5 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04
6 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04
7 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03
8 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03
9 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0
10 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0
11 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0
12 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0
13 INT191577 Binding of Pde6b and Tst 1 0.02 0.48 0
14 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0
15 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0
16 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0
17 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0
18 INT273772 BCKDHA Positive_regulation of Positive_regulation of NARFL 1 0.03 1.21 0
19 INT213751 Binding of FUT2 and ISCA1 1 0.00 0.16 0
20 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0
21 INT315532 Binding of NFS1 and ISCU 1 0.19 0.37 0
22 INT247889 Positive_regulation of Narfl Positive_regulation of CASP3 1 0.00 0.84 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for iron-sulfur cluster assembly. They are ordered first by their pain relevance and then by number of times they were reported in iron-sulfur cluster assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74
2 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41
3 INT1982 Regulation of NARFL 119 0.49 116.2 14.35
4 INT17451 Positive_regulation of Tst 23 0.67 8.85 9.52
5 INT3107 Regulation of Tst 11 0.54 4.83 7.85
6 INT27774 Gene_expression of Tst 13 0.68 12.86 4.83
7 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47
8 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16
9 INT272274 Localization of NARFL 24 0.60 27.55 1.18
10 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98
11 INT39369 Binding of NARFL 14 0.29 16.7 0.93
12 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93
13 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86
14 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84
15 INT122834 Negative_regulation of Positive_regulation of Tst 2 0.38 0.46 0.79
16 INT3108 Binding of Tst 11 0.32 13.37 0.77
17 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74
18 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73
19 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68
20 INT157227 Localization of Tst 9 0.74 6.78 0.58
21 INT236981 Negative_regulation of ISCA1 1 0.05 2.45 0.55
22 INT150258 Positive_regulation of Gene_expression of Tst 2 0.34 3.54 0.45
23 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31
24 INT272231 Regulation of Localization of Tst 1 0.05 1.17 0.24
25 INT221496 Localization of ISCA1 4 0.73 2.12 0.23
26 INT274271 Negative_regulation of Negative_regulation of NARFL 1 0.06 5.13 0.22
27 INT139526 Positive_regulation of Positive_regulation of Tst 1 0.41 0.13 0.21
28 INT274273 Regulation of Gene_expression of NARFL 3 0.10 4.39 0.2
29 INT236980 Gene_expression of ISCA1 9 0.53 2.43 0.19
30 INT274339 Negative_regulation of Binding of NARFL 1 0.06 0.58 0.17
31 INT58816 Regulation of Regulation of NARFL 2 0.11 1.39 0.16
32 INT199642 Positive_regulation of Fxn 3 0.41 3.6 0.14
33 INT199640 Positive_regulation of Positive_regulation of Fxn 2 0.41 2.97 0.14
34 INT247865 Gene_expression of Narfl 1 0.09 9.22 0.13
35 INT199652 Negative_regulation of Fxn 3 0.54 12.37 0.11
36 INT306408 Regulation of Gene_expression of Tst 1 0.05 1.69 0.11
37 INT247866 Localization of Narfl 1 0.10 1.98 0.09
38 INT199646 Transcription of Fxn 2 0.67 4.78 0.08
39 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08
40 INT199643 Phosphorylation of Fxn 1 0.40 1.04 0.08
41 INT272530 Negative_regulation of Localization of NARFL 3 0.09 2.98 0.07
42 INT199655 Negative_regulation of Gene_expression of Fxn 2 0.47 3.34 0.07
43 INT247873 Binding of Narfl 1 0.05 1.33 0.07
44 INT236982 Positive_regulation of ISCA1 1 0.06 0.5 0.07
45 INT330979 Protein_catabolism of NARFL 1 0.02 0.84 0.06
46 INT199654 Positive_regulation of Gene_expression of Fxn 3 0.64 2.95 0.05
47 INT247867 Positive_regulation of Positive_regulation of Narfl 1 0.11 5.16 0.05
48 INT99965 Positive_regulation of Negative_regulation of NARFL 6 0.40 4.5 0.04
49 INT199641 Regulation of Transcription of Fxn 1 0.29 1.89 0.04
50 INT199648 Regulation of Fxn 1 0.29 2.14 0.04
51 INT199651 Binding of Fxn 3 0.30 1.45 0.03
52 INT274269 Transcription of NARFL 1 0.09 1.13 0.03
53 INT315624 Positive_regulation of Gene_expression of ISCU 1 0.38 0.23 0.03
54 INT247878 Negative_regulation of Positive_regulation of Narfl 1 0.06 2.14 0.03
55 INT291518 Positive_regulation of Negative_regulation of Fxn 1 0.47 1.1 0.03
56 INT274274 Positive_regulation of Transcription of NARFL 1 0.06 1.13 0.03
57 INT174850 Binding of ISCU 2 0.33 0.51 0
58 INT325463 Positive_regulation of Binding of NARFL 2 0.15 0.76 0
59 INT315561 Regulation of ISCU 2 0.35 1.1 0
60 INT274340 Regulation of Localization of NARFL 1 0.06 0.63 0
61 INT315581 Positive_regulation of Phosphorylation of ISCU 1 0.44 0.33 0
62 INT291511 Positive_regulation of Transcription of Fxn 1 0.47 0.09 0
63 INT315602 Binding of ISCA1 1 0.30 0 0
64 INT309010 Transcription of Tst 1 0.33 0.41 0
65 INT309009 Negative_regulation of Binding of Tst 1 0.20 1.5 0
66 INT291516 Negative_regulation of Transcription of Fxn 1 0.54 0.77 0
67 INT325466 Positive_regulation of Localization of NARFL 1 0.04 0.53 0
68 INT247872 Positive_regulation of Gene_expression of Narfl 1 0.07 0.44 0
69 INT315634 Negative_regulation of Binding of ISCU 1 0.33 0.28 0
70 INT315597 Negative_regulation of ISCU 1 0.51 0.22 0
71 INT247862 Regulation of Narfl 1 0.06 0.67 0
72 INT174845 Protein_catabolism of ISCU 1 0.04 0.25 0
73 INT247869 Regulation of Positive_regulation of Narfl 1 0.06 1.85 0
74 INT165077 Positive_regulation of Localization of Tst 1 0.39 0 0
75 INT247877 Negative_regulation of Gene_expression of Narfl 1 0.06 1.05 0
76 INT315615 Positive_regulation of ISCU 1 0.44 0.11 0
77 INT315639 Localization of ISCU 1 0.66 0 0
78 INT259719 Negative_regulation of Regulation of NARFL 1 0.01 1.67 0
79 INT315629 Phosphorylation of ISCU 1 0.71 0.33 0
80 INT291507 Regulation of Negative_regulation of Fxn 1 0.37 0.87 0
81 INT247876 Negative_regulation of Localization of Narfl 1 0.06 0.94 0
82 INT247879 Regulation of Gene_expression of Narfl 1 0.04 0.66 0
83 INT291512 Regulation of Gene_expression of Fxn 1 0.37 0.06 0
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