GO:0016235

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Name aggresome
Categary Component
Go Slim No
Go Link GO:0016235
Unique Molecular Interactions 84
Total Molecular Interactions 107
Total Single Events 1101
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aggresome. They are ordered first by their pain relevance and then by number of times they were reported for aggresome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
2 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
3 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
4 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
5 INT251166 Clu Positive_regulation of Trpc3 1 0.09 0.75 0.67
6 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
7 INT251188 Clu Positive_regulation of TRPV1 1 0.01 0.23 0.64
8 INT7402 Positive_regulation of Ucma Positive_regulation of Localization of Gast 1 0.50 0 0.62
9 INT251167 Clu Positive_regulation of Trpc6 1 0.12 0.2 0.6
10 INT251168 Clu Positive_regulation of Trpc7 1 0.15 0.2 0.59
11 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
12 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
13 INT52301 Ucma Regulation of Localization of Gast 1 0.28 0 0.41
14 INT52302 Ucma Positive_regulation of Localization of Gast 1 0.47 0 0.41
15 INT52298 Regulation of Ucma Regulation of Gast 1 0.28 0 0.41
16 INT52300 Ucma Regulation of Sst 1 0.13 0 0.41
17 INT52299 Ucma Regulation of Gast 1 0.28 0 0.41
18 INT135015 MGP Negative_regulation of Cabin1 1 0.01 0.26 0.4
19 INT51341 Binding of Pomc and Clu 1 0.14 0 0.38
20 INT190806 Ubd Regulation of Abp1 1 0.20 0.82 0.32
21 INT135014 Binding of Ephb1 and Cabin1 1 0.09 0.32 0.3
22 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
23 INT305623 Ca2 Positive_regulation of Cabin1 1 0.00 0.27 0.27
24 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22
25 INT251162 Clu Positive_regulation of Gene_expression of Trpv1 1 0.20 0.07 0.18
26 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
27 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
28 INT51344 Binding of Clu and Vtn 1 0.06 0 0.1
29 INT274156 Negative_regulation of Cabin1 Negative_regulation of Gene_expression of Vegfa 1 0.08 0.28 0.09
30 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
31 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
32 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
33 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06
34 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
35 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
36 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04
37 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04
38 INT306505 Binding of Clu and Tnf 1 0.24 0.4 0.04
39 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04
40 INT306501 Negative_regulation of Binding of Clu and Tnf 1 0.29 0.4 0.04
41 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03
42 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
43 INT294293 Binding of RCAN1 and CABIN1 1 0.03 0 0.03
44 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
45 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
46 INT238627 Binding of Cadm1 and Card14 1 0.00 0.08 0
47 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
48 INT306500 Clu Regulation of Esr1 1 0.22 0.13 0
49 INT298450 Binding of CDH1 and Efs 1 0.03 0.96 0
50 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
51 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
52 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
53 INT238629 Binding of Sdc2 and Card14 1 0.00 0.08 0
54 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
55 INT306509 Binding of XRCC6 and Clu 1 0.37 0.27 0
56 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
57 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
58 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
59 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0
60 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
61 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0
62 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
63 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
64 INT337407 MIR200A Positive_regulation of CDH1 1 0.00 0.29 0
65 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
66 INT294313 Gene_expression of CABIN1 Positive_regulation of IL11 1 0.03 0.06 0
67 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
68 INT298438 Binding of CDH1 and SNAI1 1 0.14 1.16 0
69 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
70 INT232594 CDH1 Regulation of HEPACAM 1 0.01 1.02 0
71 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aggresome. They are ordered first by their pain relevance and then by number of times they were reported in aggresome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
2 INT66460 Negative_regulation of Cabin1 15 0.43 8.98 8.03
3 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
4 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
5 INT51337 Binding of Clu 3 0.12 0.05 5.45
6 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73
7 INT35946 Positive_regulation of Clu 12 0.69 4.92 2.73
8 INT48539 Positive_regulation of Cabin1 8 0.32 0.63 2.68
9 INT24887 Localization of CABIN1 1 0.71 1.19 2.39
10 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
11 INT49347 Negative_regulation of Clu 4 0.58 1.63 1.79
12 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72
13 INT24888 Gene_expression of CABIN1 3 0.56 0.91 1.71
14 INT7398 Positive_regulation of Ucma 3 0.45 0 1.66
15 INT35944 Regulation of Clu 4 0.20 0.15 1.3
16 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28
17 INT132191 Regulation of Cabin1 6 0.45 2.96 1.28
18 INT251180 Phosphorylation of Clu 1 0.29 0.79 1.22
19 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21
20 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
21 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15
22 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15
23 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
24 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07
25 INT41009 Gene_expression of Ubd 2 0.52 1.67 1.07
26 INT126876 Gene_expression of Cabin1 6 0.63 2.81 0.92
27 INT100273 Localization of Clu 4 0.61 0.49 0.88
28 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
29 INT70666 Positive_regulation of CLU 16 0.45 12.95 0.74
30 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
31 INT94233 Positive_regulation of Gene_expression of Clu 3 0.69 2.64 0.71
32 INT86370 Regulation of CDH1 10 0.54 13.89 0.7
33 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
34 INT134276 Positive_regulation of Positive_regulation of Cabin1 1 0.03 0.13 0.65
35 INT94232 Negative_regulation of Gene_expression of Clu 2 0.43 1.17 0.63
36 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
37 INT135294 Negative_regulation of Positive_regulation of Clu 1 0.37 0.35 0.59
38 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
39 INT126877 Positive_regulation of Gene_expression of Cabin1 3 0.56 1.97 0.57
40 INT190799 Positive_regulation of Ubd 1 0.41 1.15 0.54
41 INT251182 Regulation of Phosphorylation of Clu 1 0.16 0.13 0.52
42 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
43 INT135013 Binding of Cabin1 2 0.32 0.72 0.46
44 INT233552 Positive_regulation of Gene_expression of Clu 3 0.59 9.31 0.45
45 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
46 INT52297 Gene_expression of Ucma 2 0.65 1.3 0.41
47 INT52296 Regulation of Gene_expression of Ucma 1 0.44 0 0.41
48 INT163489 Binding of CDH1 13 0.19 8.63 0.35
49 INT127871 Regulation of Gene_expression of CDH1 4 0.44 2.34 0.34
50 INT190797 Positive_regulation of Positive_regulation of Ubd 1 0.41 0.83 0.32
51 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
52 INT48538 Regulation of Positive_regulation of Cabin1 1 0.01 0.28 0.29
53 INT122985 Negative_regulation of Gene_expression of CLU 4 0.57 4.58 0.27
54 INT145259 Binding of CLU 1 0.03 0.84 0.27
55 INT69595 Localization of Ucma 1 0.73 0 0.26
56 INT69596 Positive_regulation of Localization of Ucma 1 0.49 0 0.26
57 INT88004 Binding of CABIN1 2 0.03 0.11 0.25
58 INT312887 Gene_expression of Hdac6 1 0.60 1.28 0.25
59 INT312883 Regulation of Regulation of Hdac6 1 0.40 0.38 0.24
60 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
61 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
62 INT122987 Negative_regulation of CLU 5 0.42 4.58 0.21
63 INT35945 Positive_regulation of Regulation of Clu 1 0.35 0 0.2
64 INT254701 Transcription of CDH1 6 0.67 2.5 0.17
65 INT41008 Binding of Ubd 1 0.31 0.66 0.17
66 INT126875 Negative_regulation of Gene_expression of Cabin1 2 0.47 1.04 0.16
67 INT122984 Localization of CLU 2 0.78 2.46 0.16
68 INT122989 Positive_regulation of Localization of CLU 2 0.45 1.81 0.16
69 INT312881 Positive_regulation of Hdac6 1 0.45 0.67 0.15
70 INT164160 Localization of CDH1 8 0.66 3.39 0.14
71 INT122986 Positive_regulation of Gene_expression of CLU 3 0.67 2.37 0.14
72 INT164520 Regulation of CABIN1 2 0.26 0.1 0.13
73 INT190802 Negative_regulation of Positive_regulation of Ubd 1 0.35 0.19 0.12
74 INT294331 Positive_regulation of CABIN1 1 0.03 0 0.11
75 INT274155 Localization of Cabin1 1 0.57 0.55 0.1
76 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
77 INT233567 Positive_regulation of Clu 3 0.59 2.91 0.09
78 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
79 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
80 INT342696 Gene_expression of Park2 1 0.65 1.19 0.08
81 INT274153 Negative_regulation of Binding of Cabin1 1 0.28 0.2 0.08
82 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
83 INT294336 Negative_regulation of Binding of CABIN1 1 0.03 0 0.07
84 INT53875 Protein_catabolism of Ubd 1 0.51 0.06 0.06
85 INT269223 Positive_regulation of Localization of CDH1 1 0.38 0.84 0.06
86 INT233554 Negative_regulation of Gene_expression of Clu 2 0.39 1.96 0.05
87 INT233550 Localization of Clu 2 0.69 4.52 0.05
88 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
89 INT312877 Positive_regulation of Negative_regulation of Hdac6 1 0.45 0 0.05
90 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
91 INT317299 Binding of Park2 1 0.36 0.61 0.04
92 INT251361 Transcription of Cdh1 1 0.36 0 0.04
93 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
94 INT161524 Regulation of Clu 4 0.38 3.18 0.03
95 INT312888 Phosphorylation of Hdac6 1 0.73 0 0.03
96 INT287933 Negative_regulation of Binding of CDH1 1 0.03 0.65 0.03
97 INT294360 Negative_regulation of Gene_expression of CABIN1 1 0.03 0.06 0.03
98 INT287949 Positive_regulation of Positive_regulation of CDH1 3 0.06 1.4 0
99 INT233556 Regulation of Gene_expression of Clu 2 0.33 1.45 0
100 INT251359 Regulation of Cdh1 2 0.34 0.47 0
101 INT189878 Localization of Cdh1 2 0.56 0.34 0
102 INT263281 Negative_regulation of Transcription of CDH1 2 0.41 1.84 0
103 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
104 INT312873 Negative_regulation of Gene_expression of Hdac6 1 0.38 0 0
105 INT342695 Phosphorylation of Park2 1 0.79 0.62 0
106 INT298446 Negative_regulation of Negative_regulation of CDH1 1 0.15 0.59 0
107 INT49344 Negative_regulation of Transcription of Clu 1 0.35 0.07 0
108 INT49345 Transcription of Clu 1 0.58 0.2 0
109 INT312885 Binding of Hdac6 1 0.43 0 0
110 INT350778 Regulation of Binding of CDH1 1 0.02 0.29 0
111 INT104519 Regulation of Ubd 1 0.21 0 0
112 INT312874 Regulation of Phosphorylation of Hdac6 1 0.40 0 0
113 INT233564 Regulation of Positive_regulation of Clu 1 0.38 0.98 0
114 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
115 INT104518 Negative_regulation of Regulation of Ubd 1 0.33 0 0
116 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
117 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
118 INT287950 Negative_regulation of Positive_regulation of CDH1 1 0.03 0.56 0
119 INT259156 Protein_catabolism of CDH1 1 0.16 0.38 0
120 INT346315 Negative_regulation of Regulation of CDH1 1 0.04 0.47 0
121 INT206738 Regulation of CLU 1 0.44 1.15 0
122 INT312876 Negative_regulation of Transcription of Hdac6 1 0.38 0 0
123 INT104520 Negative_regulation of Ubd 1 0.35 0 0
124 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
125 INT354842 Protein_catabolism of CLU 1 0.28 1.6 0
126 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
127 INT306487 Binding of Clu 1 0.24 0.27 0
128 INT49348 Regulation of Transcription of Clu 1 0.50 0.13 0
129 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
130 INT318803 Regulation of Gene_expression of CLU 1 0.21 0.9 0
131 INT312875 Transcription of Hdac6 1 0.61 0 0
132 INT233557 Transcription of Clu 1 0.45 0.77 0
133 INT294330 Positive_regulation of Gene_expression of CABIN1 1 0.03 0.06 0
134 INT321753 Regulation of Card14 1 0.01 0.06 0
135 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
136 INT269224 Regulation of Transcription of CDH1 1 0.20 0.86 0
137 INT318804 Negative_regulation of Localization of CLU 1 0.18 1.33 0
138 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
139 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
140 INT174716 Regulation of Ucma 1 0.60 0.15 0
141 INT312878 Protein_catabolism of Hdac6 1 0.88 0 0
142 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
143 INT238565 Binding of Card14 1 0.00 0.09 0
144 INT337474 Positive_regulation of Binding of CDH1 1 0.07 0.54 0
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