GO:0016236

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Name macroautophagy
Categary Process
Go Slim No
Go Link GO:0016236
Unique Molecular Interactions 23
Total Molecular Interactions 37
Total Single Events 363
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for macroautophagy. They are ordered first by their pain relevance and then by number of times they were reported for macroautophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87
2 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
3 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
4 INT153738 TNFRSF11A Positive_regulation of SQSTM1 1 0.05 1.22 0.13
5 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1
6 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 0.43 0.58 0.1
7 INT237670 SQSTM1 Regulation of PDB1 1 0.34 1.13 0.06
8 INT219857 Binding of Krt20 and Nbr1 1 0.00 1.31 0.04
9 INT313305 SQSTM1 Regulation of NFE2L2 1 0.35 0.09 0
10 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 0.39 0.39 0
11 INT313297 SQSTM1 Positive_regulation of Positive_regulation of NFE2L2 1 0.26 0 0
12 INT313304 Binding of SQSTM1 and GOPC 1 0.04 0.24 0
13 INT237669 Binding of PDB1 and SQSTM1 1 0.27 2.55 0
14 INT188435 PDB1 Negative_regulation of Binding of SQSTM1 1 0.41 0.49 0
15 INT313303 Negative_regulation of SQSTM1 Positive_regulation of GOPC 1 0.05 0.39 0
16 INT313292 Positive_regulation of SQSTM1 Regulation of NFE2L2 1 0.26 0.09 0
17 INT313295 Binding of SQSTM1 and GABARAPL2 1 0.32 0.13 0
18 INT313310 KEAP1 Regulation of Gene_expression of SQSTM1 1 0.43 0.35 0
19 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0
20 INT313311 SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.45 0 0
21 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0
22 INT313294 Negative_regulation of SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.39 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for macroautophagy. They are ordered first by their pain relevance and then by number of times they were reported in macroautophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48
2 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34
3 INT31994 Negative_regulation of Nbr1 7 0.41 5.54 2.29
4 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56
5 INT22456 Localization of Nbr1 4 0.70 2.71 0.95
6 INT22455 Binding of Nbr1 8 0.21 10.57 0.93
7 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
8 INT188448 Negative_regulation of SQSTM1 4 0.53 3.75 0.55
9 INT188444 Binding of SQSTM1 5 0.44 4.69 0.54
10 INT21873 Positive_regulation of Gene_expression of Nbr1 5 0.50 2.09 0.51
11 INT37068 Regulation of Gene_expression of Nbr1 1 0.41 0.76 0.47
12 INT35539 Positive_regulation of Positive_regulation of Nbr1 2 0.47 2.52 0.41
13 INT35540 Negative_regulation of Positive_regulation of Nbr1 1 0.25 1.03 0.31
14 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
15 INT194031 Regulation of SQSTM1 2 0.41 2.07 0.27
16 INT141896 Positive_regulation of SQSTM1 6 0.50 5.58 0.26
17 INT312887 Gene_expression of Hdac6 1 0.60 1.28 0.25
18 INT312883 Regulation of Regulation of Hdac6 1 0.40 0.38 0.24
19 INT313313 Positive_regulation of Gene_expression of SQSTM1 1 0.63 1.25 0.23
20 INT188446 Gene_expression of SQSTM1 5 0.71 5.34 0.18
21 INT312881 Positive_regulation of Hdac6 1 0.45 0.67 0.15
22 INT313318 Negative_regulation of Localization of SQSTM1 1 0.39 0.59 0.14
23 INT313320 Localization of SQSTM1 1 0.68 0.59 0.14
24 INT313312 Positive_regulation of Binding of SQSTM1 1 0.46 0.44 0.11
25 INT312877 Positive_regulation of Negative_regulation of Hdac6 1 0.45 0 0.05
26 INT312888 Phosphorylation of Hdac6 1 0.73 0 0.03
27 INT312873 Negative_regulation of Gene_expression of Hdac6 1 0.38 0 0
28 INT312885 Binding of Hdac6 1 0.43 0 0
29 INT312874 Regulation of Phosphorylation of Hdac6 1 0.40 0 0
30 INT313326 Regulation of Negative_regulation of SQSTM1 1 0.41 0 0
31 INT313315 Protein_catabolism of SQSTM1 1 0.52 0.12 0
32 INT312876 Negative_regulation of Transcription of Hdac6 1 0.38 0 0
33 INT285452 Regulation of Gene_expression of SQSTM1 1 0.09 0 0
34 INT312875 Transcription of Hdac6 1 0.61 0 0
35 INT312878 Protein_catabolism of Hdac6 1 0.88 0 0
36 INT313314 Positive_regulation of Negative_regulation of SQSTM1 1 0.40 0 0
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