GO:0016281

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Name eukaryotic translation initiation factor 4F complex
Categary Component
Go Slim No
Go Link GO:0016281
Unique Molecular Interactions 27
Total Molecular Interactions 48
Total Single Events 85
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for eukaryotic translation initiation factor 4F complex. They are ordered first by their pain relevance and then by number of times they were reported for eukaryotic translation initiation factor 4F complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
2 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
3 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
4 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
5 INT341239 Binding of EIF4E and Eif4e 1 0.08 0.23 0.12
6 INT341238 Binding of EIF4E and Eif4g3 1 0.03 0.23 0.12
7 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09
8 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07
9 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 0.20 0.42 0.06
10 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
11 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
12 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 0.17 0.14 0.03
13 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
14 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0
15 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
16 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
17 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 0.18 0 0
18 INT217777 EIF4E Regulation of Gene_expression of MAP3K3 1 0.05 0.19 0
19 INT341234 Eif4g3 Positive_regulation of Binding of EIF4E 1 0.04 0 0
20 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 0.11 0 0
21 INT217790 EIF4E Regulation of Gene_expression of RASGRP1 1 0.01 0.19 0
22 INT293811 Negative_regulation of EIF4E Negative_regulation of Gene_expression of CCND3 1 0.02 0.32 0
23 INT341230 Eif4g3 Positive_regulation of EIF4E 1 0.04 0 0
24 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
25 INT341224 Eif4g3 Positive_regulation of Eif4e 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for eukaryotic translation initiation factor 4F complex. They are ordered first by their pain relevance and then by number of times they were reported in eukaryotic translation initiation factor 4F complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136788 Regulation of Eif4e 3 0.61 0 1.61
2 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
3 INT136785 Phosphorylation of Eif4e 2 0.82 0 1.1
4 INT341195 Binding of Eif4e 1 0.38 3.87 0.92
5 INT136780 Positive_regulation of Eif4e 1 0.50 0 0.55
6 INT341182 Regulation of Eif4e 1 0.35 0.75 0.25
7 INT341163 Positive_regulation of Eif4e 1 0.54 0.56 0.19
8 INT211839 Binding of EIF4E 8 0.36 0.79 0.18
9 INT257859 Negative_regulation of Eif4e 1 0.23 1.07 0.16
10 INT353246 Gene_expression of EIF4G1 1 0.06 1.23 0.14
11 INT341192 Phosphorylation of Eif4e 1 0.49 0.36 0.1
12 INT308214 Binding of EIF4G2 1 0.35 0.32 0.08
13 INT341167 Negative_regulation of Binding of Eif4e 1 0.33 0.23 0.03
14 INT341200 Negative_regulation of Eif4e 1 0.46 0.14 0.03
15 INT341189 Positive_regulation of Positive_regulation of Eif4e 1 0.36 0.13 0.03
16 INT227664 Phosphorylation of EIF4E 6 0.46 0.74 0
17 INT217806 Gene_expression of EIF4E 2 0.27 0.68 0
18 INT293778 Positive_regulation of EIF4E 2 0.45 0.42 0
19 INT303322 Positive_regulation of Phosphorylation of EIF4A2 1 0.08 0.16 0
20 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0
21 INT211836 Binding of EIF4G1 1 0.12 0.07 0
22 INT293768 Regulation of Binding of EIF4E 1 0.18 0.13 0
23 INT341184 Positive_regulation of Localization of Eif4e 1 0.39 0 0
24 INT227668 Positive_regulation of Phosphorylation of EIF4E 1 0.20 0.15 0
25 INT276879 Regulation of Phosphorylation of EIF4E 1 0.25 0.21 0
26 INT293780 Positive_regulation of Binding of EIF4E 1 0.20 0.13 0
27 INT341191 Localization of Eif4e 1 0.63 0 0
28 INT303318 Phosphorylation of EIF4A2 1 0.11 0.16 0
29 INT341209 Binding of EIF4A2 1 0.06 0 0
30 INT341208 Negative_regulation of Binding of EIF4E 1 0.14 0 0
31 INT341188 Positive_regulation of Binding of Eif4e 1 0.34 0.18 0
32 INT293775 Regulation of EIF4E 1 0.24 0.64 0
33 INT293761 Negative_regulation of EIF4E 1 0.17 0.85 0
34 INT351112 Positive_regulation of Positive_regulation of EIF4E 1 0.45 0.22 0
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