GO:0016303

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Name 1-phosphatidylinositol-3-kinase activity
Categary Function
Go Slim No
Go Link GO:0016303
Unique Molecular Interactions 395
Total Molecular Interactions 480
Total Single Events 2217
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 1-phosphatidylinositol-3-kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for 1-phosphatidylinositol-3-kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132228 Negative_regulation of Binding of Pik3cg and Sh2d6 1 0.07 1.96 3.6
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
4 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
5 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
6 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 0.04 1.35 1.4
7 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
8 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
9 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
10 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
11 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
12 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
13 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
14 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01
15 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
16 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
17 INT96260 Pik3cd Regulation of Plcg2 1 0.02 0 0.92
18 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
19 INT132227 Binding of Pik3cg and Sh2d6 1 0.06 0.49 0.9
20 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87
21 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
22 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
23 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68
24 INT190178 PIK3CG Regulation of MMP12 1 0.09 0 0.65
25 INT168206 Binding of Pik3cd and Sh3 1 0.14 0.37 0.65
26 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
27 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
28 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
29 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
30 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
31 INT116753 Ngf Regulation of Pik3cd 1 0.40 0.29 0.63
32 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
33 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
34 INT261482 Pik3cb Positive_regulation of Phosphorylation of Ephb1 1 0.23 0.67 0.58
35 INT190181 Positive_regulation of PIK3CA Positive_regulation of MMP12 1 0.01 0.54 0.56
36 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
37 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
38 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
39 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
40 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
41 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
42 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
43 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
44 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
45 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
46 INT322394 Hist1h1t Positive_regulation of Pik3cb 1 0.01 0 0.42
47 INT157650 Phosphorylation of Prkcc Positive_regulation of Pik3c3 1 0.51 0 0.41
48 INT157647 Positive_regulation of Oprd1 Positive_regulation of Pik3c3 1 0.01 0 0.4
49 INT157649 Prkcc Regulation of Pik3c3 1 0.30 0 0.39
50 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39
51 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
52 INT157648 Binding of Prkcc and Pik3c3 1 0.39 0 0.36
53 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
54 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
55 INT122755 Helt Positive_regulation of Pik3cb 1 0.00 0.19 0.35
56 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34
57 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
58 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
59 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
60 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31
61 INT185141 Pik3r1 Positive_regulation of Snrpd1 1 0.00 0.16 0.29
62 INT60181 Binding of HTR5A and Pik3c3 1 0.03 0.1 0.29
63 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28
64 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28
65 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
66 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
67 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
68 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
69 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
70 INT121581 Negative_regulation of PIK3CG Positive_regulation of GDF15 1 0.36 0.59 0.24
71 INT122576 Pik3cd Positive_regulation of Phosphorylation of Nos3 1 0.28 0.45 0.21
72 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
73 INT352945 Fig4 Regulation of Negative_regulation of Pik3cb 1 0.03 0.38 0.19
74 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18
75 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18
76 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18
77 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18
78 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18
79 INT121580 PIK3CG Regulation of Gene_expression of GDF15 1 0.48 0.4 0.18
80 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
81 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
82 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
83 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
84 INT203591 Positive_regulation of PIK3CG Positive_regulation of Protein_catabolism of LAMB2 1 0.00 0.46 0.14
85 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
86 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
87 INT311731 Plat Regulation of Protein_catabolism of Pik3cd 1 0.31 0.71 0.13
88 INT129094 Binding of GRP and Pik3r1 1 0.00 0.49 0.12
89 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
90 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
91 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12
92 INT166153 Pik3r1 Regulation of Gene_expression of Ccr9 1 0.36 0.78 0.12
93 INT129073 Binding of GRP and PIK3CG 1 0.00 0.49 0.12
94 INT317888 Binding of Eef1a1 and Pik3r1 1 0.01 1.04 0.11
95 INT291550 St8sia2 Positive_regulation of Pik3cb 1 0.05 0.36 0.11
96 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
97 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
98 INT257873 Ins1 Positive_regulation of Pik3cg 1 0.13 1.05 0.11
99 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1
100 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
101 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
102 INT328435 PIK3CD Positive_regulation of Gene_expression of VEGFA 1 0.23 0.64 0.09
103 INT205204 LPA Positive_regulation of Positive_regulation of Pik3c3 1 0.02 0.22 0.09
104 INT213051 Hdl1 Positive_regulation of Pik3r1 1 0.13 1.93 0.09
105 INT246846 Binding of PIK3CA and Irs1 1 0.39 0.14 0.08
106 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08
107 INT331796 Akt1 Negative_regulation of Negative_regulation of Pik3r1 1 0.04 0.88 0.08
108 INT246845 Binding of PIK3CA and Ppp1r13b 1 0.13 0.15 0.08
109 INT340553 Pik3r1 Regulation of Gene_expression of Fbxo32 1 0.04 0.52 0.07
110 INT340320 Binding of Shc1 and Positive_regulation of Pik3r1 1 0.23 0 0.07
111 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
112 INT92584 Negative_regulation of PIK3C3 Negative_regulation of Gene_expression of PTGER2 1 0.01 0.46 0.07
113 INT120569 Binding of Egfr and Pik3r1 1 0.40 1.22 0.06
114 INT267012 Pik3cg Positive_regulation of Arc 1 0.01 0.1 0.06
115 INT352943 Pik3cb Positive_regulation of Pdk1 1 0.09 0.21 0.06
116 INT267013 Pik3cg Positive_regulation of Egr2 1 0.01 0.1 0.06
117 INT120570 Positive_regulation of Binding of Egfr and Pik3r1 1 0.55 1.22 0.06
118 INT352942 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.33 0.21 0.06
119 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
120 INT352941 Pik3cb Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.21 0.06
121 INT257227 Pik3cd Positive_regulation of Akt1 1 0.01 0.33 0.05
122 INT238314 Pik3cb Negative_regulation of Localization of Slc2a4 1 0.06 0.25 0.05
123 INT328438 PRB4 Negative_regulation of PIK3CD 1 0.06 0.29 0.05
124 INT213016 Regulation of Hdl1 Positive_regulation of Pik3r1 1 0.09 0.97 0.05
125 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05
126 INT199106 Negative_regulation of Pik3r1 Negative_regulation of Gene_expression of Ros1 1 0.03 0.08 0.04
127 INT257875 Agt Positive_regulation of Pik3cg 1 0.06 0.37 0.04
128 INT213031 Positive_regulation of Pik3r1 Positive_regulation of Gene_expression of Nos3 1 0.10 0.8 0.04
129 INT341021 Positive_regulation of Cp Positive_regulation of Positive_regulation of PIK3CB 1 0.00 0.15 0.04
130 INT341016 Reln Positive_regulation of Positive_regulation of PIK3CB 1 0.01 0.15 0.04
131 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03
132 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
133 INT257866 Phosphorylation of Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
134 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
135 INT179951 Binding of PIK3CA and Ins1 1 0.39 0.32 0.03
136 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
137 INT328436 PRB4 Negative_regulation of Gene_expression of PIK3CD 1 0.07 0.24 0.03
138 INT257876 Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
139 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
140 INT328430 PRB4 Regulation of Positive_regulation of PIK3CD 1 0.06 0.4 0.03
141 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03
142 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
143 INT179950 Binding of PIK3CA and Irs1 1 0.32 0.31 0.03
144 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
145 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03
146 INT295476 PIK3CA Regulation of Gene_expression of TNF 1 0.00 0.05 0.03
147 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03
148 INT267011 Pik3cg Regulation of Bdnf 1 0.06 0.07 0.03
149 INT176540 Pik3cd Positive_regulation of Spp1 1 0.11 1.8 0.03
150 INT176131 Binding of AKT1 and PIK3CG 2 0.15 1.08 0
151 INT306646 Mapk1 Regulation of Pik3r1 1 0.03 0.39 0
152 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0
153 INT207817 Negative_regulation of Parp1 Positive_regulation of Atm 1 0.53 0.2 0
154 INT201767 Igf1 Positive_regulation of PIK3CG 1 0.00 0.84 0
155 INT226190 Binding of Igf1 and Positive_regulation of Pik3cb 1 0.17 1.04 0
156 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
157 INT176551 Binding of Pik3r1 and Spp1 1 0.03 0.65 0
158 INT322849 Binding of PIK3CD and PDCD10 1 0.16 0 0
159 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0
160 INT325770 Binding of EPOR and PIK3R2 1 0.01 0.18 0
161 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
162 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0
163 INT246799 Pik3c3 Positive_regulation of Negative_regulation of Ogg1 1 0.04 0 0
164 INT207815 Parp1 Negative_regulation of Phosphorylation of Atm 1 0.42 0.15 0
165 INT207816 Parp1 Regulation of Positive_regulation of Atm 1 0.51 0.21 0
166 INT336033 PIK3CG Regulation of AKT1 1 0.03 0.43 0
167 INT333456 ATM Positive_regulation of CHEK2 1 0.20 0 0
168 INT328431 PIK3CD Negative_regulation of Gene_expression of VEGFA 1 0.22 0.29 0
169 INT307457 Negative_regulation of Pik3cb Positive_regulation of Gsk3a 1 0.06 0.08 0
170 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0
171 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
172 INT340927 Negative_regulation of PIK3CB Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
173 INT176137 Negative_regulation of Binding of AKT1 and PIK3CG 1 0.17 0.25 0
174 INT309870 Arl6ip6 Negative_regulation of Pik3cb 1 0.00 0.73 0
175 INT341025 PIK3CB Positive_regulation of Regulation of Vim 1 0.01 0 0
176 INT333446 ATM Positive_regulation of CHEK1 1 0.20 0 0
177 INT354122 MIR126 Regulation of PIK3CG 1 0.03 2.01 0
178 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
179 INT226207 Binding of Ins1 and Positive_regulation of Pik3cb 1 0.01 2.08 0
180 INT322844 Binding of KDR and PIK3CD 1 0.04 0 0
181 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0
182 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0
183 INT271101 PIK3CB Regulation of Akt1 1 0.01 0.72 0
184 INT253565 Akt1 Positive_regulation of Positive_regulation of Pik3r1 1 0.10 0 0
185 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
186 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
187 INT333451 ATM Positive_regulation of Negative_regulation of CHEK1 1 0.14 0 0
188 INT262759 PIK3CG Positive_regulation of MTOR 1 0.38 0.54 0
189 INT340929 VLDLR Positive_regulation of PIK3CB 1 0.01 0.06 0
190 INT225903 Binding of GAB1 and PIK3CG 1 0.01 0.13 0
191 INT211572 Binding of Kit and Pik3r1 1 0.21 0.06 0
192 INT201773 Binding of BCL2L1 and Positive_regulation of Negative_regulation of PIK3CG 1 0.01 0.3 0
193 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0
194 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0
195 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0
196 INT341020 PIK3CB Regulation of Gene_expression of Fabp7 1 0.02 0 0
197 INT176553 Pik3r1 Positive_regulation of Positive_regulation of Mapk14 1 0.02 0.41 0
198 INT176542 Pik3r1 Positive_regulation of Positive_regulation of Mapk1 1 0.01 0.41 0
199 INT226193 Gtf3a Positive_regulation of Pik3cb 1 0.00 1.02 0
200 INT333450 ATM Positive_regulation of Negative_regulation of MDM2 1 0.18 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 1-phosphatidylinositol-3-kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in 1-phosphatidylinositol-3-kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
2 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59
3 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
4 INT94573 Negative_regulation of Pik3cb 42 0.50 15.83 15.4
5 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18
6 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
7 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
8 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
9 INT96258 Positive_regulation of Pik3cd 14 0.43 8.74 5.16
10 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
11 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
12 INT118274 Positive_regulation of Positive_regulation of PIK3CG 8 0.64 4.81 4.62
13 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
14 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
15 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
16 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97
17 INT116643 Phosphorylation of Pik3cb 12 0.80 4.73 3.87
18 INT91887 Negative_regulation of Pik3cg 12 0.41 5.01 3.67
19 INT116645 Regulation of Pik3cb 11 0.41 3.78 3.43
20 INT60174 Positive_regulation of Pik3c3 12 0.67 1.05 3.23
21 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
22 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78
23 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48
24 INT112026 Gene_expression of Pik3cd 6 0.72 4.89 2.34
25 INT148025 Localization of Pik3cg 1 0.58 0.69 2.34
26 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
27 INT74306 Negative_regulation of Pik3cd 7 0.24 1.93 2.27
28 INT128745 Positive_regulation of Positive_regulation of Pik3cb 4 0.56 0.95 2.24
29 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
30 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
31 INT149335 Gene_expression of Pik3cb 10 0.57 2.93 1.82
32 INT243799 Gene_expression of PIK3CD 15 0.45 6.63 1.5
33 INT148026 Positive_regulation of Pik3cg 4 0.45 0.54 1.46
34 INT94572 Negative_regulation of Pik3c3 5 0.13 1.37 1.41
35 INT109301 Positive_regulation of Phosphorylation of Pik3r1 5 0.42 1.45 1.38
36 INT250707 Gene_expression of PIK3CB 15 0.31 5.4 1.34
37 INT121723 Regulation of Positive_regulation of Pik3cb 1 0.44 0.61 1.29
38 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26
39 INT112028 Regulation of Pik3cd 2 0.19 0.22 1.25
40 INT148027 Localization of Pik3c3 1 0.24 0.34 1.17
41 INT122574 Phosphorylation of Pik3cd 4 0.58 2.01 1.14
42 INT264969 Localization of PIK3CD 5 0.50 0.64 1.13
43 INT157642 Gene_expression of Pik3c3 7 0.75 0.68 1.08
44 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02
45 INT1940 Localization of PIK3C2A 8 0.78 7.28 1.01
46 INT2991 Regulation of PIK3C2A 6 0.60 4.46 0.99
47 INT250708 Negative_regulation of PIK3CB 17 0.30 3.09 0.94
48 INT150942 Regulation of Pik3c3 2 0.18 0.96 0.94
49 INT288191 Positive_regulation of Localization of Pik3r1 4 0.15 1.27 0.81
50 INT194633 Negative_regulation of Gene_expression of Pik3cb 3 0.21 1.83 0.79
51 INT157643 Phosphorylation of Pik3c3 1 0.78 0 0.79
52 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75
53 INT11709 Positive_regulation of Gene_expression of PIK3C2A 2 0.49 1.88 0.74
54 INT28118 Binding of Atm 13 0.38 12.24 0.68
55 INT190187 Regulation of Gene_expression of PIK3CG 1 0.13 0 0.65
56 INT166456 Negative_regulation of Gene_expression of Pik3r1 4 0.41 1.72 0.64
57 INT120963 Negative_regulation of Negative_regulation of Pik3cb 2 0.17 1.4 0.64
58 INT264964 Positive_regulation of Localization of PIK3CD 1 0.13 0.05 0.62
59 INT135666 Negative_regulation of Negative_regulation of Pik3r1 2 0.29 0.3 0.6
60 INT135668 Negative_regulation of Negative_regulation of Pik3cd 2 0.13 0.29 0.6
61 INT48212 Binding of ATM 5 0.47 3.89 0.57
62 INT160778 Transcription of ATM 1 0.40 1.03 0.57
63 INT132781 Phosphorylation of PIK3CG 8 0.52 4.83 0.53
64 INT120961 Positive_regulation of Phosphorylation of Pik3cb 3 0.26 1.02 0.53
65 INT122573 Negative_regulation of Phosphorylation of Pik3cd 2 0.31 1.04 0.53
66 INT160776 Positive_regulation of Positive_regulation of ATM 2 0.43 0.94 0.53
67 INT157638 Positive_regulation of Gene_expression of Pik3c3 2 0.48 0.46 0.52
68 INT205200 Positive_regulation of Pik3c3 7 0.08 2.76 0.51
69 INT230238 Binding of Pik3cb 6 0.21 2.27 0.51
70 INT157645 Negative_regulation of Pik3c3 6 0.41 2.88 0.5
71 INT154565 Regulation of Positive_regulation of PIK3CD 2 0.09 1.59 0.45
72 INT240033 Phosphorylation of PIK3R2 1 0.02 1.82 0.45
73 INT337345 Regulation of Gene_expression of PIK3CD 1 0.20 0 0.43
74 INT133704 Regulation of Pik3cg 2 0.44 0.46 0.42
75 INT157639 Negative_regulation of Positive_regulation of Pik3c3 1 0.41 0 0.41
76 INT157644 Negative_regulation of Phosphorylation of Pik3c3 1 0.41 0 0.4
77 INT337344 Negative_regulation of Negative_regulation of PIK3CD 1 0.19 0 0.4
78 INT315892 Negative_regulation of Binding of ATM 1 0.07 1.41 0.4
79 INT157640 Positive_regulation of Phosphorylation of Pik3c3 1 0.48 0 0.4
80 INT132780 Positive_regulation of Phosphorylation of PIK3CG 1 0.01 0.37 0.4
81 INT154768 Negative_regulation of ATM 10 0.57 7.05 0.39
82 INT120968 Negative_regulation of Phosphorylation of Pik3cb 1 0.12 0.89 0.39
83 INT157641 Regulation of Pik3c3 1 0.59 0 0.39
84 INT144275 Negative_regulation of Atm 9 0.59 8.48 0.36
85 INT194629 Positive_regulation of Gene_expression of Pik3cb 4 0.24 0.67 0.36
86 INT89403 Negative_regulation of PIK3CA 19 0.57 11.74 0.35
87 INT168766 Positive_regulation of Binding of Pik3r1 3 0.21 1.54 0.35
88 INT257764 Positive_regulation of Positive_regulation of PIK3CA 5 0.44 2.72 0.31
89 INT212985 Negative_regulation of Positive_regulation of Pik3r1 3 0.19 3.28 0.3
90 INT185119 Regulation of Positive_regulation of Pik3r1 3 0.13 0.45 0.3
91 INT78025 Negative_regulation of PIK3C2A 2 0.22 1.14 0.28
92 INT167438 Localization of ATM 3 0.55 1.61 0.27
93 INT3979 Positive_regulation of Positive_regulation of PIK3C2A 2 0.45 1.49 0.27
94 INT197121 Positive_regulation of Atm 24 0.69 6.81 0.25
95 INT250712 Regulation of PIK3CB 2 0.15 0.88 0.25
96 INT214364 Positive_regulation of Negative_regulation of Pik3cb 1 0.42 0.19 0.25
97 INT254654 Positive_regulation of Localization of PIK3C2A 1 0.49 0.84 0.25
98 INT35719 Gene_expression of Atm 34 0.78 15.75 0.24
99 INT120969 Negative_regulation of Positive_regulation of Pik3cb 2 0.19 0.69 0.24
100 INT89399 Negative_regulation of Positive_regulation of PIK3CA 3 0.57 1 0.22
101 INT176145 Positive_regulation of Gene_expression of PIK3CG 3 0.20 1.36 0.22
102 INT222130 Gene_expression of Pik3c3 3 0.12 0.62 0.21
103 INT276186 Negative_regulation of Gene_expression of Pik3c3 1 0.07 0.3 0.21
104 INT147732 Binding of PIK3CA 3 0.36 1.13 0.2
105 INT178118 Positive_regulation of PIK3CB 12 0.32 5.06 0.19
106 INT92586 Negative_regulation of PIK3C3 2 0.03 0.73 0.18
107 INT236698 Transcription of Pik3r1 1 0.15 1.3 0.18
108 INT246833 Positive_regulation of Binding of PIK3CA 1 0.49 0.29 0.16
109 INT302261 Regulation of PIK3CD 7 0.29 5.34 0.15
110 INT309653 Negative_regulation of Localization of Pik3r1 1 0.14 0.55 0.15
111 INT147731 Phosphorylation of PIK3CA 3 0.44 1.93 0.14
112 INT296668 Negative_regulation of Positive_regulation of PIK3C2A 1 0.41 0.54 0.14
113 INT243793 Phosphorylation of PIK3CD 5 0.42 1.74 0.13
114 INT311714 Protein_catabolism of Pik3cd 1 0.54 0.63 0.13
115 INT311707 Positive_regulation of Protein_catabolism of Pik3cd 1 0.30 0.69 0.13
116 INT278288 Regulation of Localization of ATM 1 0.09 0.95 0.13
117 INT167440 Regulation of ATM 2 0.20 0.68 0.12
118 INT137758 Negative_regulation of Pik3cd 1 0.07 0.27 0.11
119 INT351430 Binding of PIK3C3 1 0.01 0 0.11
120 INT129082 Positive_regulation of Pik3r1 1 0.00 0.47 0.11
121 INT288190 Regulation of Localization of Pik3r1 1 0.04 0.07 0.1
122 INT221200 Positive_regulation of Positive_regulation of Pik3c3 1 0.04 0.07 0.1
123 INT207804 Negative_regulation of Gene_expression of Atm 2 0.59 6.22 0.09
124 INT284321 Gene_expression of PIK3R2 1 0.20 0.97 0.09
125 INT262775 Negative_regulation of Phosphorylation of PIK3CG 1 0.28 1.1 0.09
126 INT147733 Regulation of Binding of PIK3CA 1 0.10 0.23 0.08
127 INT328448 Negative_regulation of Gene_expression of PIK3CD 1 0.21 0.84 0.08
128 INT230866 Negative_regulation of Gene_expression of PIK3CG 2 0.28 1.37 0.07
129 INT207806 Phosphorylation of Atm 8 0.81 3.07 0.06
130 INT230239 Positive_regulation of Localization of Pik3cb 1 0.06 0.56 0.06
131 INT230240 Localization of Pik3cb 1 0.09 0.56 0.06
132 INT308619 Regulation of Phosphorylation of Pik3r1 1 0.09 1.06 0.06
133 INT284333 Positive_regulation of PIK3R2 1 0.12 0.42 0.05
134 INT341853 Negative_regulation of Negative_regulation of PIK3CG 1 0.14 0.85 0.04
135 INT257854 Positive_regulation of Positive_regulation of Pik3cg 1 0.27 0.11 0.04
136 INT246821 Binding of Pik3c3 1 0.02 0.26 0.04
137 INT257860 Regulation of Negative_regulation of Pik3cg 1 0.26 1.1 0.04
138 INT201693 Negative_regulation of Positive_regulation of PIK3CG 1 0.05 1.04 0.04
139 INT246820 Negative_regulation of Binding of Pik3c3 1 0.02 0.26 0.04
140 INT212459 Positive_regulation of Binding of Atm 1 0.40 0.88 0.04
141 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03
142 INT176162 Binding of PIK3CG 5 0.15 1.3 0.03
143 INT207803 Regulation of Atm 3 0.41 1.15 0.03
144 INT250703 Negative_regulation of Negative_regulation of PIK3CB 2 0.20 1.16 0.03
145 INT176150 Localization of PIK3CA 2 0.73 0.22 0.03
146 INT236921 Positive_regulation of Positive_regulation of Pik3r2 1 0.01 0.13 0.03
147 INT236919 Positive_regulation of Pik3r2 1 0.01 0.13 0.03
148 INT176160 Positive_regulation of Localization of PIK3CA 1 0.13 0.22 0.03
149 INT207807 Localization of Atm 4 0.74 0.21 0
150 INT320732 Binding of PIK3CD 3 0.20 1.66 0
151 INT250702 Positive_regulation of Gene_expression of PIK3CB 3 0.23 1.79 0
152 INT347315 Binding of PIK3CB 2 0.19 1.57 0
153 INT176151 Regulation of Negative_regulation of PIK3CG 2 0.28 0.92 0
154 INT198037 Regulation of PIK3CA 2 0.28 2.63 0
155 INT340980 Negative_regulation of Positive_regulation of PIK3CB 2 0.12 0.59 0
156 INT322525 Phosphorylation of PIK3CB 2 0.42 1.09 0
157 INT157290 Regulation of Gene_expression of ATM 2 0.44 0.86 0
158 INT291365 Positive_regulation of Gene_expression of PIK3CA 2 0.41 5.76 0
159 INT252642 Transcription of Atm 1 0.53 0.18 0
160 INT246778 Positive_regulation of Positive_regulation of Pik3c3 1 0.06 0 0
161 INT290913 Negative_regulation of Binding of Pik3cb 1 0.21 0 0
162 INT315886 Regulation of Positive_regulation of PIK3CA 1 0.10 0.53 0
163 INT256098 Negative_regulation of Phosphorylation of Pik3cg 1 0.12 0.16 0
164 INT239161 Positive_regulation of Negative_regulation of Pik3r1 1 0.30 0.77 0
165 INT246766 Positive_regulation of Gene_expression of Pik3c3 1 0.04 0.32 0
166 INT354742 Phosphorylation of ATM 1 0.50 1.74 0
167 INT268311 Negative_regulation of Regulation of Pik3r2 1 0.45 0.44 0
168 INT256090 Phosphorylation of Pik3cg 1 0.24 0.16 0
169 INT268303 Negative_regulation of Pik3r2 1 0.33 0.22 0
170 INT208050 Localization of PIK3C3 1 0.01 0.13 0
171 INT340989 Localization of PIK3CB 1 0.06 0 0
172 INT252645 Positive_regulation of Gene_expression of Atm 1 0.50 2.35 0
173 INT311855 Regulation of Negative_regulation of PIK3CD 1 0.04 0.28 0
174 INT268309 Regulation of Pik3r2 1 0.47 0.22 0
175 INT277420 Positive_regulation of Gene_expression of Pik3cd 1 0.05 0.29 0
176 INT208038 Regulation of PIK3C3 1 0.00 0.64 0
177 INT193985 Regulation of Phosphorylation of PIK3CG 1 0.03 0.32 0
178 INT271099 Regulation of Gene_expression of PIK3CB 1 0.08 0.62 0
179 INT252644 Regulation of Gene_expression of Atm 1 0.27 0.39 0
180 INT176159 Regulation of Positive_regulation of PIK3CG 1 0.18 0.21 0
181 INT322533 Negative_regulation of Gene_expression of PIK3CB 1 0.11 0.57 0
182 INT307484 Regulation of Negative_regulation of Pik3cb 1 0.22 0.14 0
183 INT207808 Positive_regulation of Positive_regulation of Atm 1 0.50 0.08 0
184 INT252643 Negative_regulation of Positive_regulation of Atm 1 0.38 0.6 0
185 INT198035 Regulation of Negative_regulation of PIK3CA 1 0.15 0.95 0
186 INT340998 Positive_regulation of Positive_regulation of PIK3CB 1 0.04 0.14 0
187 INT198030 Regulation of Regulation of PIK3CA 1 0.24 1.08 0
188 INT322530 Negative_regulation of Phosphorylation of PIK3CB 1 0.15 0.24 0
189 INT322527 Regulation of Negative_regulation of PIK3CB 1 0.07 0 0
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