GO:0016310

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Name phosphorylation
Categary Process
Go Slim No
Go Link GO:0016310
Unique Molecular Interactions 3501
Total Molecular Interactions 4577
Total Single Events 31281
Pain Genes Associated 265

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
3 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
4 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
5 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
6 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
7 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
8 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
9 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
10 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
11 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
12 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
13 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
14 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
15 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
16 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
17 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
18 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
19 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
20 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
21 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
22 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
23 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
24 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
25 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
26 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
27 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
28 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
29 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
30 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
31 INT92182 Mir702 Negative_regulation of Adk 1 0.07 1.29 2.47
32 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
33 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
34 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
35 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
36 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
37 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
38 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
39 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
40 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
41 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
42 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
43 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
44 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
45 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
46 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
47 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
48 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
49 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
50 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
51 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
52 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
53 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
54 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
55 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
56 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
57 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
58 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
59 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
60 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
61 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
62 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
63 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
64 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
65 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
66 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
67 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
68 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
69 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
70 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
71 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
72 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
73 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
74 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
75 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
76 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
77 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
78 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
79 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
80 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
81 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
82 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
83 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
84 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
85 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
86 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
87 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
88 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
89 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
90 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
91 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
92 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
93 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
94 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
95 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
96 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
97 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
98 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
99 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
100 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
101 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
102 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
103 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 0.04 1.35 1.4
104 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
105 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
106 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
107 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
108 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
109 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
110 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
111 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
112 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
113 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
114 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
115 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
116 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
117 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
118 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
119 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
120 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
121 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
122 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
123 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
124 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
125 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
126 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
127 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
128 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
129 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27
130 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27
131 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
132 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 0.02 0 1.26
133 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
134 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
135 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
136 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
137 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
138 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
139 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
140 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23
141 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
142 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
143 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
144 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
145 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
146 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
147 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
148 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
149 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
150 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
151 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
152 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
153 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
154 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
155 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
156 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
157 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
158 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
159 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
160 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
161 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
162 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
163 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
164 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
165 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
166 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
167 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
168 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
169 INT76378 Binding of Cit and Flvcr2 1 0.09 0.17 1.15
170 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
171 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
172 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
173 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
174 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
175 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
176 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
177 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
178 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
179 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
180 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12
181 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
182 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
183 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
184 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
185 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
186 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
187 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
188 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
189 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
190 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
191 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
192 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
193 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
194 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
195 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
196 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
197 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
198 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
199 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
200 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
3 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
4 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
5 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
6 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
7 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
8 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
9 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
10 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
11 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
12 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
13 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
14 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
15 INT4153 Binding of Insrr 109 0.40 17.99 72.15
16 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
17 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
18 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
19 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
20 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
21 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
22 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
23 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
24 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
25 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
26 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
27 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
28 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
29 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
30 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
31 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
32 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
33 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38
34 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
35 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
36 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
37 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
38 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
39 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
40 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
41 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
42 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
43 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
44 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
45 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
46 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
47 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
48 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
49 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
50 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
51 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
52 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
53 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
54 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
55 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
56 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
57 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
58 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
59 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
60 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
61 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
62 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
63 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
64 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39
65 INT117527 Binding of Prkca 25 0.48 6.43 21.05
66 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
67 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
68 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
69 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
70 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
71 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
72 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
73 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
74 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53
75 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
76 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
77 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
78 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
79 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
80 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
81 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
82 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
83 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59
84 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
85 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
86 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
87 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
88 INT79458 Localization of Prkca 30 0.81 11.13 15.78
89 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
90 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
91 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
92 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
93 INT94573 Negative_regulation of Pik3cb 42 0.50 15.83 15.4
94 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
95 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
96 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
97 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
98 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
99 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
100 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
101 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
102 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
103 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
104 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65
105 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
106 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
107 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
108 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
109 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
110 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
111 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
112 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
113 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
114 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
115 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
116 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
117 INT3074 Negative_regulation of Chkb 29 0.57 14 12.04
118 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
119 INT100821 Localization of Ros1 59 0.60 45.26 11.92
120 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
121 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
122 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
123 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
124 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
125 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
126 INT38255 Localization of Chkb 32 0.80 10.98 11.07
127 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
128 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9
129 INT118678 Phosphorylation of Camk4 22 0.82 9.4 10.7
130 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
131 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
132 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
133 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
134 INT790 Gene_expression of Mastl 22 0.68 4.56 10.23
135 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14
136 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
137 INT50615 Positive_regulation of Positive_regulation of Insrr 11 0.19 5.5 10.05
138 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
139 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
140 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
141 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
142 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
143 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
144 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
145 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
146 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
147 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
148 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
149 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
150 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
151 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
152 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17
153 INT123040 Phosphorylation of Grk4 12 0.60 0.31 9.14
154 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
155 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07
156 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
157 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
158 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
159 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
160 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
161 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
162 INT20999 Negative_regulation of Binding of Insrr 17 0.47 3.53 8.93
163 INT141185 Regulation of Ros1 30 0.24 20.73 8.88
164 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88
165 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
166 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
167 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
168 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
169 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
170 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
171 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
172 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
173 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
174 INT12859 Localization of Insrr 16 0.32 2.68 8.07
175 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
176 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
177 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
178 INT35307 Regulation of Adk 11 0.35 3.21 7.79
179 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
180 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49
181 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
182 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
183 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
184 INT13348 Negative_regulation of Mastl 11 0.36 3.33 7.28
185 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
186 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
187 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
188 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
189 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
190 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
191 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
192 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
193 INT92734 Binding of Ephb1 5 0.37 3.86 7.02
194 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
195 INT110104 Localization of Prkce 17 0.79 3.75 6.92
196 INT62260 Negative_regulation of Gene_expression of Insrr 10 0.06 1.36 6.92
197 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
198 INT74161 Positive_regulation of Negative_regulation of Adk 10 0.50 3.3 6.77
199 INT73709 Binding of Mastl 11 0.40 3.39 6.76
200 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
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