GO:0016327

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Name apicolateral plasma membrane
Categary Component
Go Slim No
Go Link GO:0016327
Unique Molecular Interactions 105
Total Molecular Interactions 190
Total Single Events 1027
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apicolateral plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for apicolateral plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT309708 Palm Regulation of Positive_regulation of Penk 1 0.19 1.25 0.91
2 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
3 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
4 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6
5 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
6 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
7 INT296453 Binding of Gria1 and Mpdz 1 0.02 0.23 0.31
8 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29
9 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
10 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19
11 INT332540 Cxadr Regulation of Gene_expression of AD5 1 0.09 0.25 0.14
12 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
13 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
14 INT217530 Binding of Tjp1 and Tjp2 1 0.10 0.91 0.1
15 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09
16 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
17 INT205244 Cldn3 Regulation of Gene_expression of Ocln 1 0.04 0.29 0.07
18 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
19 INT205229 Cldn2 Regulation of Gene_expression of Ocln 1 0.07 0.29 0.07
20 INT205236 Cldn5 Regulation of Tjp1 1 0.03 0.28 0.07
21 INT205240 Cldn3 Regulation of Tjp1 1 0.04 0.29 0.07
22 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
23 INT205231 Cldn2 Regulation of Tjp1 1 0.07 0.29 0.07
24 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
25 INT205248 Cldn2 Regulation of Gene_expression of Tjp1 1 0.07 0.29 0.07
26 INT205233 Cldn5 Regulation of Gene_expression of Ocln 1 0.03 0.28 0.07
27 INT205247 Cldn3 Regulation of Gene_expression of Tjp1 1 0.04 0.29 0.07
28 INT205246 Cldn5 Regulation of Gene_expression of Tjp1 1 0.03 0.28 0.07
29 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
30 INT178984 Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
31 INT177260 CXADR Positive_regulation of SLCO1B1 1 0.34 0 0.05
32 INT265564 Ocln Regulation of Gene_expression of Cdh5 1 0.01 1.03 0.05
33 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
34 INT178985 Positive_regulation of Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
35 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
36 INT177291 CXADR Positive_regulation of ABCC2 1 0.22 0 0.05
37 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
38 INT177288 Binding of CXADR and SV2A 1 0.32 0 0.04
39 INT177279 Binding of CXADR and TNFRSF25 1 0.18 0 0.04
40 INT177268 Binding of CXADR and HLA-DRB4 1 0.20 0 0.04
41 INT177281 Binding of CA2 and CXADR 1 0.31 0 0.04
42 INT355224 Phosphorylation of Ocln Negative_regulation of Binding of Tjp2 1 0.06 0.09 0.04
43 INT355219 Phosphorylation of Ocln Positive_regulation of Binding of Tjp2 1 0.07 0.09 0.04
44 INT217529 Dss1 Negative_regulation of Gene_expression of Tjp1 1 0.07 0.54 0.04
45 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
46 INT305883 Pcx Negative_regulation of Binding of Tjp1 1 0.04 0.11 0.04
47 INT305875 Pcx Negative_regulation of Binding of Ocln 1 0.03 0.11 0.04
48 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
49 INT177253 Binding of CXADR and FAUP1 1 0.02 0 0.04
50 INT317959 Negative_regulation of Ephb1 Negative_regulation of Cldn4 1 0.10 0.27 0.03
51 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03
52 INT217858 AD5 Positive_regulation of Gene_expression of CXADR 1 0.17 0.65 0.03
53 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
54 INT177258 SV2A Regulation of CXADR 1 0.63 0 0.03
55 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
56 INT317961 Negative_regulation of Ephb1 Negative_regulation of Negative_regulation of Cldn4 1 0.10 0.27 0.03
57 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
58 INT330484 Binding of Cxadr and Hspg2 1 0.18 0.52 0.03
59 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
60 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
61 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
62 INT177277 CXADR Positive_regulation of CYP2B6 1 0.47 0 0
63 INT177254 Binding of CXADR and NCOA2 1 0.19 0 0
64 INT217857 Binding of CXADR and AD5 1 0.18 3.55 0
65 INT247821 Binding of Tjp1 and Gopc 1 0.03 0.4 0
66 INT355220 Negative_regulation of Binding of Ocln and Tjp1 1 0.21 0.14 0
67 INT177283 Binding of CXADR and GOPC 1 0.16 0 0
68 INT119504 asa Negative_regulation of Gene_expression of Tjp1 1 0.05 0 0
69 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
70 INT177267 Binding of CXADR and NCOA3 1 0.17 0 0
71 INT305879 Binding of Ocln and Pcx 1 0.03 0 0
72 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
73 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
74 INT305881 Positive_regulation of Binding of Ocln and Tjp1 1 0.01 0 0
75 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
76 INT177284 FAUP1 Positive_regulation of CXADR 1 0.03 0 0
77 INT247823 Binding of Cxadr and Tjp1 1 0.08 0.4 0
78 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
79 INT245821 Binding of Ppp2r2b and Ocln 1 0.00 0.81 0
80 INT234970 Binding of Jup and Lat 1 0.01 0 0
81 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
82 INT297690 Binding of Fut1 and Ocln 1 0.02 0 0
83 INT217861 Negative_regulation of Binding of CXADR and AD5 1 0.16 0.45 0
84 INT355221 Binding of Espn and Ocln 1 0.01 0 0
85 INT177289 Binding of CXADR and NCOA1 1 0.17 0 0
86 INT177286 Binding of CXADR and MED1 1 0.27 0 0
87 INT177300 FAUP1 Positive_regulation of Binding of CXADR 1 0.03 0 0
88 INT217859 Binding of CXADR and RPS4X 1 0.03 0.17 0
89 INT245832 VEGFA Positive_regulation of Phosphorylation of Ocln 1 0.04 1.61 0
90 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
91 INT245830 VEGFA Regulation of Ocln 1 0.02 0.83 0
92 INT305874 Binding of Pcx and Tjp1 1 0.03 0 0
93 INT177287 CXADR Positive_regulation of ABCB1 1 0.39 0 0
94 INT355225 Binding of Ocln and Tjp2 1 0.07 0 0
95 INT355222 Positive_regulation of Binding of Ocln and Tjp1 1 0.18 0 0
96 INT177266 GSR Positive_regulation of Gene_expression of CXADR 1 0.13 0 0
97 INT245824 Plg Regulation of Negative_regulation of Ocln 1 0.06 0.57 0
98 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
99 INT234982 Binding of Jup and Pkp1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for apicolateral plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in apicolateral plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
2 INT105284 Gene_expression of Ocln 39 0.78 14.98 5.08
3 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67
4 INT125447 Positive_regulation of CLDN4 14 0.70 4.71 4.45
5 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
6 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
7 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
8 INT205216 Gene_expression of Cldn4 47 0.53 9.47 2.08
9 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06
10 INT125451 Gene_expression of CLDN4 5 0.78 4.75 2.01
11 INT124077 Negative_regulation of Ocln 13 0.57 8.62 1.8
12 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
13 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
14 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
15 INT105286 Negative_regulation of Gene_expression of Ocln 7 0.31 2.52 1.35
16 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
17 INT125446 Negative_regulation of Positive_regulation of CLDN4 2 0.59 2.14 1.3
18 INT113865 Binding of CXADR 35 0.46 3.18 1.12
19 INT105285 Regulation of Gene_expression of Tjp1 6 0.26 2.73 1.08
20 INT125904 Positive_regulation of Ocln 6 0.45 2.06 1.06
21 INT125448 Positive_regulation of Gene_expression of CLDN4 3 0.70 1.01 1.02
22 INT105283 Positive_regulation of Gene_expression of Tjp1 4 0.68 1.86 1.01
23 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
24 INT205213 Positive_regulation of Gene_expression of Cldn4 12 0.47 3.37 0.8
25 INT245796 Phosphorylation of Ocln 6 0.33 2.76 0.76
26 INT174158 Negative_regulation of Cxadr 23 0.55 13.74 0.72
27 INT113866 Regulation of CXADR 7 0.59 1.67 0.67
28 INT177316 Localization of CXADR 9 0.77 1.05 0.64
29 INT159141 Negative_regulation of Gene_expression of Tjp1 7 0.57 5.44 0.62
30 INT125449 Regulation of Gene_expression of CLDN4 2 0.60 1.07 0.61
31 INT159143 Gene_expression of Ocln 14 0.42 5.25 0.57
32 INT158898 Positive_regulation of Gene_expression of Ocln 5 0.22 2.06 0.57
33 INT327693 Regulation of Palm 1 0.18 0 0.54
34 INT125445 Positive_regulation of Positive_regulation of CLDN4 1 0.70 0.52 0.53
35 INT159140 Positive_regulation of Gene_expression of Tjp1 11 0.61 5.04 0.5
36 INT101365 Binding of Tjp1 8 0.11 1.66 0.49
37 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
38 INT120226 Positive_regulation of Cxadr 4 0.44 2.54 0.48
39 INT304633 Positive_regulation of Phosphorylation of Ocln 2 0.28 0.19 0.47
40 INT242168 Transcription of JUP 4 0.67 1.17 0.46
41 INT309707 Positive_regulation of Palm 1 0.39 0.28 0.46
42 INT125450 Negative_regulation of Gene_expression of CLDN4 1 0.43 0.47 0.46
43 INT159146 Regulation of Gene_expression of Tjp1 13 0.44 6.91 0.45
44 INT61822 Negative_regulation of Ocln 8 0.41 5.33 0.45
45 INT247794 Localization of Cxadr 4 0.76 3.17 0.45
46 INT205205 Regulation of Gene_expression of Cldn4 1 0.42 1.27 0.36
47 INT205215 Localization of Tjp1 2 0.29 0.95 0.35
48 INT159145 Negative_regulation of Gene_expression of Ocln 4 0.32 3.07 0.34
49 INT124076 Binding of Ocln 3 0.37 1.01 0.34
50 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
51 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
52 INT205218 Localization of Ocln 3 0.46 1.71 0.32
53 INT205217 Negative_regulation of Gene_expression of Cldn4 1 0.40 1.22 0.31
54 INT110772 Binding of Tjp1 2 0.32 1.12 0.3
55 INT264637 Localization of CLDN4 3 0.73 0.85 0.29
56 INT217501 Positive_regulation of Tjp1 8 0.49 2.91 0.28
57 INT117249 Negative_regulation of Tjp1 4 0.29 1.34 0.27
58 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
59 INT217515 Binding of Ocln 7 0.22 2.12 0.25
60 INT217504 Regulation of Tjp1 9 0.32 2.44 0.23
61 INT61818 Positive_regulation of Ocln 6 0.23 4.11 0.22
62 INT245799 Protein_catabolism of Ocln 2 0.62 1.78 0.22
63 INT245798 Positive_regulation of Negative_regulation of Ocln 2 0.27 1.9 0.22
64 INT300430 Negative_regulation of Phosphorylation of Ocln 1 0.19 0.43 0.21
65 INT291082 Positive_regulation of Protein_catabolism of Ocln 1 0.31 0.96 0.2
66 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
67 INT291080 Negative_regulation of Protein_catabolism of Ocln 1 0.26 0.96 0.2
68 INT130125 Regulation of Ocln 5 0.44 0.87 0.19
69 INT205211 Localization of Cldn4 1 0.54 0.69 0.19
70 INT159142 Regulation of Gene_expression of Ocln 3 0.25 1.36 0.16
71 INT332537 Transcription of Cxadr 1 0.46 0.54 0.15
72 INT158896 Positive_regulation of Tjp1 3 0.31 0.36 0.14
73 INT158902 Negative_regulation of Gene_expression of Tjp1 1 0.21 0.14 0.14
74 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
75 INT217507 Localization of Tjp1 5 0.57 1.65 0.13
76 INT149030 Phosphorylation of Tjp1 4 0.58 0.96 0.13
77 INT130126 Regulation of Tjp1 3 0.43 0.54 0.13
78 INT217500 Phosphorylation of Ocln 1 0.24 0.96 0.13
79 INT177302 Transcription of CXADR 20 0.69 0.49 0.12
80 INT177315 Regulation of Gene_expression of CXADR 4 0.26 0.12 0.11
81 INT205210 Transcription of Ocln 2 0.32 0.58 0.11
82 INT268656 Binding of CLDN4 1 0.47 0.88 0.11
83 INT205220 Transcription of Tjp1 1 0.26 0.44 0.11
84 INT355213 Negative_regulation of Binding of Tjp1 1 0.29 0.34 0.1
85 INT355218 Regulation of Binding of Tjp1 1 0.18 0.34 0.1
86 INT113863 Regulation of Regulation of CXADR 1 0.06 0 0.1
87 INT296441 Binding of Mpdz 1 0.03 0.07 0.1
88 INT177339 Positive_regulation of Localization of CXADR 1 0.45 0 0.1
89 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
90 INT217522 Transcription of Tjp1 1 0.38 0.91 0.09
91 INT159144 Positive_regulation of Gene_expression of Ocln 1 0.27 1.04 0.09
92 INT309877 Localization of JUP 2 0.73 1.38 0.08
93 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
94 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
95 INT61820 Positive_regulation of Negative_regulation of Ocln 1 0.15 1.65 0.08
96 INT109652 Negative_regulation of Tjp1 3 0.32 0.92 0.07
97 INT217516 Negative_regulation of Phosphorylation of Ocln 1 0.17 0.77 0.07
98 INT217508 Negative_regulation of Phosphorylation of Tjp1 1 0.30 0.77 0.07
99 INT234866 Regulation of Jup 2 0.08 0.58 0.06
100 INT217502 Positive_regulation of Phosphorylation of Ocln 1 0.13 0.19 0.06
101 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
102 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
103 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
104 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
105 INT303527 Transcription of Ocln 1 0.20 0.35 0.06
106 INT177313 Phosphorylation of CXADR 1 0.78 0 0.05
107 INT177314 Negative_regulation of Binding of CXADR 4 0.41 0.07 0.04
108 INT265559 Regulation of Gene_expression of Ocln 2 0.13 1.01 0.04
109 INT355217 Negative_regulation of Binding of Ocln 1 0.27 0.21 0.04
110 INT247814 Negative_regulation of Localization of Cxadr 1 0.40 0.96 0.04
111 INT317951 Negative_regulation of Cldn4 1 0.14 0.27 0.03
112 INT205208 Positive_regulation of Cldn4 1 0.32 0.12 0.03
113 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
114 INT245802 Negative_regulation of Negative_regulation of Ocln 1 0.10 0.89 0.03
115 INT234867 Localization of Jup 1 0.24 2.84 0.03
116 INT177308 Negative_regulation of Localization of CXADR 1 0.36 0 0.03
117 INT217521 Positive_regulation of Positive_regulation of Tjp1 1 0.35 0.66 0.03
118 INT217513 Positive_regulation of Positive_regulation of Ocln 1 0.15 0.66 0.03
119 INT174192 Negative_regulation of Gene_expression of CXADR 6 0.41 2.79 0
120 INT177332 Negative_regulation of CXADR 5 0.49 0.89 0
121 INT265322 Positive_regulation of Binding of Ocln 3 0.23 0.3 0
122 INT268654 Negative_regulation of CLDN4 3 0.42 0 0
123 INT265315 Positive_regulation of Binding of Tjp1 3 0.11 0.3 0
124 INT265325 Regulation of Ocln 2 0.18 0.07 0
125 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
126 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
127 INT265333 Localization of Ocln 2 0.34 0 0
128 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
129 INT221864 Binding of JUP 2 0.36 1.05 0
130 INT221859 Binding of Jup 2 0.14 2.21 0
131 INT149029 Positive_regulation of Negative_regulation of Tjp1 1 0.36 0 0
132 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
133 INT177326 Regulation of Localization of CXADR 1 0.43 0 0
134 INT247812 Positive_regulation of Negative_regulation of Cxadr 1 0.41 0.75 0
135 INT305873 Regulation of Localization of Ocln 1 0.06 0 0
136 INT247818 Regulation of Negative_regulation of Cxadr 1 0.37 1.31 0
137 INT177331 Positive_regulation of Binding of CXADR 1 0.67 0 0
138 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
139 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
140 INT303147 Negative_regulation of Negative_regulation of CLDN4 1 0.02 0 0
141 INT265336 Positive_regulation of Localization of Ocln 1 0.23 0 0
142 INT177324 Positive_regulation of Transcription of CXADR 1 0.67 0 0
143 INT177304 Negative_regulation of Transcription of CXADR 1 0.41 0 0
144 INT217509 Positive_regulation of Regulation of Tjp1 1 0.35 0.12 0
145 INT247805 Negative_regulation of Gene_expression of Cxadr 1 0.41 1.76 0
146 INT309876 Regulation of JUP 1 0.60 0.67 0
147 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
148 INT347051 Positive_regulation of Localization of CLDN4 1 0.05 0 0
149 INT149033 Positive_regulation of Phosphorylation of Tjp1 1 0.34 0 0
150 INT265332 Regulation of Binding of Tjp1 1 0.05 0 0
151 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
152 INT265321 Negative_regulation of Binding of Tjp1 1 0.08 0.17 0
153 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
154 INT305867 Regulation of Localization of Tjp1 1 0.08 0 0
155 INT268655 Regulation of CLDN4 1 0.38 0 0
156 INT247809 Negative_regulation of Binding of Cxadr 1 0.41 2.02 0
157 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
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