GO:0016362

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Name activin receptor activity, type II
Categary Function
Go Slim No
Go Link GO:0016362
Unique Molecular Interactions 20
Total Molecular Interactions 30
Total Single Events 193
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for activin receptor activity, type II. They are ordered first by their pain relevance and then by number of times they were reported for activin receptor activity, type II. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34
2 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
3 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
4 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
5 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
6 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08
7 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
8 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
9 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
10 INT205409 Binding of BMP6 and BMPR2 1 0.07 0.05 0
11 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
12 INT205452 Binding of BMP6 and Acvr2a 1 0.03 0.05 0
13 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
14 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
15 INT222539 Negative_regulation of Binding of Inhba and Acvr2a 1 0.01 0 0
16 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
17 INT222504 Binding of Inhba and Acvr2a 1 0.01 0 0
18 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for activin receptor activity, type II. They are ordered first by their pain relevance and then by number of times they were reported in activin receptor activity, type II. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
2 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81
3 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
4 INT114664 Binding of BMP2 12 0.37 6.54 0.91
5 INT114604 Positive_regulation of Acvr2a 2 0.41 0 0.73
6 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
7 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54
8 INT85808 Localization of BMP2 7 0.77 1.94 0.51
9 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
10 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34
11 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
12 INT150332 Negative_regulation of Gene_expression of BMPR2 1 0.01 0 0.2
13 INT150331 Positive_regulation of Gene_expression of BMPR2 2 0.02 0.59 0.19
14 INT123935 Positive_regulation of BMPR2 3 0.26 1.65 0.18
15 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15
16 INT192082 Localization of BMPR2 1 0.32 0.55 0.15
17 INT166623 Binding of BMPR2 1 0.29 0.35 0.13
18 INT222585 Transcription of Acvr2a 1 0.16 0 0.13
19 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
20 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
21 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
22 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
23 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
24 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
25 INT222608 Negative_regulation of Gene_expression of Acvr2a 3 0.10 0.29 0.03
26 INT278039 Phosphorylation of BMPR2 1 0.08 0.26 0.03
27 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
28 INT222633 Negative_regulation of Acvr2a 1 0.10 0 0
29 INT286084 Regulation of Acvr2a 1 0.02 0.32 0
30 INT286081 Regulation of Gene_expression of Acvr2a 1 0.05 0.32 0
31 INT189623 Transcription of BMPR2 1 0.32 0.71 0
32 INT218282 Regulation of Acvr2a 1 0.23 0.33 0
33 INT218289 Gene_expression of Acvr2a 1 0.65 1.44 0
34 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
35 INT222620 Binding of Acvr2a 1 0.08 0 0
36 INT286082 Positive_regulation of Gene_expression of Acvr2a 1 0.06 1.25 0
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