GO:0016458

From wiki-pain
Jump to: navigation, search
Name gene silencing
Categary Process
Go Slim No
Go Link GO:0016458
Unique Molecular Interactions 23
Total Molecular Interactions 29
Total Single Events 399
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for gene silencing. They are ordered first by their pain relevance and then by number of times they were reported for gene silencing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
2 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
3 INT150793 ZNF398 Negative_regulation of Gene_expression of DNMT1 1 0.07 0.46 0.48
4 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
5 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
6 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24
7 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
8 INT254770 Regulation of Binding of DNMT1 and Igh-Dex 1 0.00 0 0.22
9 INT254771 Binding of DNMT1 and Igh-Dex 1 0.00 0 0.19
10 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15
11 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11
12 INT146754 KCNQ1 Regulation of Ros1 1 0.01 0.23 0.08
13 INT184209 IL1B Negative_regulation of Gene_expression of SOX6 1 0.46 0.05 0.03
14 INT241268 DNMT3B Positive_regulation of Gene_expression of DNMT1 1 0.19 0.67 0
15 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0
16 INT241264 DNMT1 Positive_regulation of Gene_expression of DNMT3B 1 0.19 0.67 0
17 INT290435 Positive_regulation of Binding of Mtor and Utp3 1 0.01 0.26 0
18 INT290436 Binding of Mtor and Utp3 1 0.00 0.26 0
19 INT241265 DNMT1 Positive_regulation of OPCML 1 0.31 0.68 0
20 INT241269 DNMT1 Positive_regulation of Gene_expression of GOPC 1 0.04 0.68 0
21 INT241254 DNMT1 Positive_regulation of GOPC 1 0.04 0.68 0
22 INT233117 Binding of SIRT2 and PAMR1 1 0.00 0 0
23 INT233118 Binding of SIRT2 and AICDA 1 0.00 0.21 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for gene silencing. They are ordered first by their pain relevance and then by number of times they were reported in gene silencing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83
2 INT136266 Gene_expression of KCNQ1 23 0.64 8.34 3.11
3 INT123795 Positive_regulation of KCNQ1 13 0.49 3.53 2.65
4 INT180134 Gene_expression of SIRT2 70 0.11 6.95 1.84
5 INT51584 Regulation of KCNQ1 10 0.44 3.21 1.84
6 INT87571 Negative_regulation of KCNQ1 6 0.41 1.69 1.51
7 INT180136 Localization of SIRT2 15 0.12 1.42 0.88
8 INT137788 Negative_regulation of Positive_regulation of KCNQ1 1 0.21 1.02 0.83
9 INT201859 Positive_regulation of Gene_expression of DNMT1 4 0.60 6.43 0.75
10 INT180139 Protein_catabolism of SIRT2 11 0.14 1.1 0.72
11 INT146400 Positive_regulation of DNMT1 4 0.45 0.91 0.43
12 INT180142 Negative_regulation of SIRT2 10 0.07 0.19 0.41
13 INT180138 Negative_regulation of Gene_expression of SIRT2 2 0.07 0.19 0.41
14 INT137786 Positive_regulation of Negative_regulation of KCNQ1 1 0.25 0.46 0.38
15 INT254763 Localization of DNMT1 1 0.05 0.2 0.29
16 INT136267 Binding of KCNQ1 3 0.36 3.28 0.28
17 INT180144 Binding of SIRT2 57 0.06 1.29 0.27
18 INT284938 Regulation of DNMT1 2 0.22 1.17 0.24
19 INT239610 Localization of KCNQ1 4 0.62 1.47 0.2
20 INT175663 Positive_regulation of SIRT2 56 0.14 3.58 0.17
21 INT233124 Positive_regulation of Gene_expression of SIRT2 17 0.04 0.16 0.14
22 INT216248 Negative_regulation of Gene_expression of KCNQ1 1 0.38 0.33 0.14
23 INT254335 Gene_expression of Sox6 2 0.43 0.25 0.12
24 INT258077 Negative_regulation of Gene_expression of DNMT1 2 0.30 1.27 0.12
25 INT258063 Negative_regulation of DNMT1 3 0.28 1.36 0.11
26 INT254762 Positive_regulation of Positive_regulation of DNMT1 1 0.04 0 0.09
27 INT184219 Gene_expression of SOX6 4 0.59 0.13 0.03
28 INT233125 Positive_regulation of Positive_regulation of SIRT2 4 0.04 0 0
29 INT180140 Regulation of SIRT2 3 0.04 0 0
30 INT284977 Binding of DNMT1 3 0.17 0.86 0
31 INT233126 Regulation of Gene_expression of SIRT2 2 0.03 0 0
32 INT284945 Protein_catabolism of DNMT1 2 0.32 0.47 0
33 INT180146 Positive_regulation of Binding of SIRT2 2 0.08 0 0
34 INT269895 Binding of Sox6 2 0.27 0.33 0
35 INT233120 Regulation of Binding of SIRT2 1 0.03 0 0
36 INT184226 Regulation of Negative_regulation of SOX6 1 0.34 0 0
37 INT251809 Localization of SOX6 1 0.45 0 0
38 INT184225 Regulation of Gene_expression of SOX6 1 0.47 0 0
39 INT301188 Regulation of Positive_regulation of SIRT2 1 0.03 1.05 0
40 INT284993 Positive_regulation of Protein_catabolism of DNMT1 1 0.22 0.26 0
41 INT180143 Phosphorylation of SIRT2 1 0.13 0 0
42 INT290406 Positive_regulation of Utp3 1 0.04 0.26 0
43 INT276275 Positive_regulation of Localization of SIRT2 1 0.04 0 0
44 INT276271 Transcription of SIRT2 1 0.05 0 0
45 INT184224 Negative_regulation of Gene_expression of SOX6 1 0.44 0 0
46 INT352006 Negative_regulation of Sox6 1 0.31 0.08 0
47 INT184221 Negative_regulation of SOX6 1 0.32 0 0
48 INT276273 Positive_regulation of Protein_catabolism of SIRT2 1 0.04 0.06 0
49 INT233121 Negative_regulation of Positive_regulation of SIRT2 1 0.03 0.26 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox