GO:0016499

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Name orexin receptor activity
Categary Function
Go Slim No
Go Link GO:0016499
Unique Molecular Interactions 4
Total Molecular Interactions 8
Total Single Events 290
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for orexin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for orexin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291467 Binding of Hcrt and Hcrtr1 1 0.53 0.87 0.07
2 INT336576 Binding of HCRTR1 and IGHG3 1 0.01 5.01 0
3 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for orexin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in orexin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113636 Positive_regulation of Hcrtr1 10 0.70 8.29 5.18
2 INT113634 Gene_expression of Hcrtr1 5 0.77 34.43 3.76
3 INT95321 Localization of Hcrtr1 4 0.79 14.81 1.66
4 INT148883 Gene_expression of HCRTR1 8 0.36 24.82 1.35
5 INT122903 Regulation of Hcrtr1 1 0.41 0 0.91
6 INT135295 Positive_regulation of Positive_regulation of Hcrtr1 2 0.50 0.92 0.79
7 INT148884 Negative_regulation of HCRTR1 7 0.23 7.23 0.53
8 INT114016 Binding of Hcrtr1 2 0.47 0.23 0.49
9 INT140500 Regulation of Positive_regulation of Hcrtr1 1 0.35 0.36 0.42
10 INT130105 Positive_regulation of HCRTR1 3 0.27 6.47 0.38
11 INT120210 Negative_regulation of Hcrtr1 3 0.58 1.17 0.34
12 INT336583 Positive_regulation of Gene_expression of HCRTR1 1 0.27 3.25 0.26
13 INT148885 Regulation of HCRTR1 2 0.29 3.41 0.14
14 INT120211 Positive_regulation of Negative_regulation of Hcrtr1 1 0.50 0 0.14
15 INT336580 Binding of HCRTR1 1 0.20 3.67 0.13
16 INT148886 Negative_regulation of Gene_expression of HCRTR1 2 0.23 3.42 0.05
17 INT336579 Regulation of Regulation of HCRTR1 1 0.15 1.94 0.05
18 INT291458 Positive_regulation of Gene_expression of Hcrtr1 1 0.68 11.16 0.03
19 INT336582 Positive_regulation of Binding of HCRTR1 1 0.27 0.84 0
20 INT291461 Regulation of Gene_expression of Hcrtr1 1 0.61 2.08 0
21 INT291460 Protein_catabolism of Hcrtr1 1 0.65 0.88 0
22 INT291459 Positive_regulation of Localization of Hcrtr1 1 0.49 1.06 0
23 INT336581 Regulation of Gene_expression of HCRTR1 1 0.24 0.71 0
24 INT291464 Negative_regulation of Gene_expression of Hcrtr1 1 0.43 1.8 0
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