GO:0016534

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Name cyclin-dependent protein kinase 5 activator activity
Categary Function
Go Slim No
Go Link GO:0016534
Unique Molecular Interactions 37
Total Molecular Interactions 50
Total Single Events 266
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cyclin-dependent protein kinase 5 activator activity. They are ordered first by their pain relevance and then by number of times they were reported for cyclin-dependent protein kinase 5 activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
2 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
3 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
4 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
5 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
6 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
7 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
8 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
9 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
10 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
11 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
12 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
13 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
14 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
15 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
16 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
17 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
18 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
19 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 0.10 0.3 0.04
20 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
21 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 0.16 0.23 0.04
22 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03
23 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03
24 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cyclin-dependent protein kinase 5 activator activity. They are ordered first by their pain relevance and then by number of times they were reported in cyclin-dependent protein kinase 5 activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
2 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
3 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
4 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
5 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
6 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
7 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
8 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
9 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
10 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
11 INT77663 Positive_regulation of CDK5R1 3 0.67 0.43 0.79
12 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
13 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
14 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63
15 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61
16 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
17 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
18 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
19 INT134473 Binding of Cdk5r2 2 0.19 1.34 0.39
20 INT247937 Localization of Cdk5r1 3 0.41 1.21 0.3
21 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28
22 INT273216 Negative_regulation of Gene_expression of Cdk5r1 1 0.25 1.73 0.25
23 INT326823 Positive_regulation of Localization of Cdk5r1 1 0.09 0.9 0.2
24 INT134469 Positive_regulation of Binding of Cdk5r1 1 0.35 0.4 0.18
25 INT134471 Positive_regulation of Binding of Cdk5r2 1 0.28 0.4 0.18
26 INT23890 Binding of CDK5R1 2 0.36 0.23 0.16
27 INT221969 Negative_regulation of CDK5R1 1 0.41 0.44 0.13
28 INT311866 Gene_expression of CDK5R2 1 0.06 1.06 0.11
29 INT101600 Regulation of Gene_expression of Cdk5r1 1 0.50 0.16 0.1
30 INT221976 Phosphorylation of CDK5R1 1 0.61 0.4 0.09
31 INT221965 Positive_regulation of Gene_expression of CDK5R1 1 0.67 0.29 0.08
32 INT221977 Transcription of CDK5R1 1 0.51 0.59 0.08
33 INT221975 Regulation of Transcription of CDK5R1 1 0.26 0.15 0.05
34 INT171650 Protein_catabolism of CDK5R1 2 0.63 0.47 0.04
35 INT203891 Gene_expression of Cdk5r2 1 0.30 0.19 0.03
36 INT201634 Negative_regulation of Positive_regulation of Cdk5r1 1 0.02 0.31 0
37 INT274108 Phosphorylation of Cdk5r1 1 0.01 0.84 0
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