GO:0016571

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Name histone methylation
Categary Process
Go Slim No
Go Link GO:0016571
Unique Molecular Interactions 33
Total Molecular Interactions 40
Total Single Events 395
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone methylation. They are ordered first by their pain relevance and then by number of times they were reported for histone methylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
2 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
3 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
4 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
5 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
6 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
7 INT51088 Binding of CDS1 and PRMT1 1 0.06 0 0.28
8 INT156587 Hst1 Negative_regulation of Gene_expression of Cpox 1 0.15 0.82 0.26
9 INT156589 Hst1 Negative_regulation of Mpo 1 0.41 0.95 0.26
10 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22
11 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22
12 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
13 INT318969 Mecp2 Regulation of Gene_expression of Bdnf 1 0.17 0.28 0.17
14 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13
15 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
16 INT156588 Hst1 Positive_regulation of Gene_expression of Nos2 1 0.27 0.48 0.12
17 INT247264 Mecp2 Positive_regulation of Gtf2i 1 0.02 0 0.08
18 INT248209 Camk2a Positive_regulation of Phosphorylation of Mecp2 1 0.52 0 0.08
19 INT332938 Suv39h1 Positive_regulation of Hist1h3f 1 0.06 0.12 0.03
20 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 0.30 0.43 0
21 INT225550 Binding of Mybbp1a and Carm1 1 0.06 0 0
22 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
23 INT348588 MECP2 Positive_regulation of Gene_expression of EZH2 1 0.28 0.42 0
24 INT348596 EZH2 Positive_regulation of Gene_expression of MECP2 1 0.28 0.42 0
25 INT225521 Binding of Prmt1 and Mybbp1a 1 0.05 0 0
26 INT348591 EZH2 Regulation of Negative_regulation of MECP2 1 0.15 0.73 0
27 INT348585 EZH2 Regulation of PPARG 1 0.41 0.73 0
28 INT342096 Binding of Polr2f and Ehmt1 1 0.00 0.73 0
29 INT225544 Binding of Prmt1 and Pprc1 1 0.00 0 0
30 INT342439 PPP2CA Negative_regulation of PRMT1 1 0.12 0.63 0
31 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone methylation. They are ordered first by their pain relevance and then by number of times they were reported in histone methylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
2 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
3 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
4 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
5 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
6 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
7 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
8 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
9 INT144542 Positive_regulation of Phosphorylation of Mecp2 2 0.68 1.43 1.5
10 INT318963 Positive_regulation of Mecp2 5 0.50 1.78 1.49
11 INT247263 Regulation of Mecp2 4 0.60 1.31 1.32
12 INT280467 Negative_regulation of Mecp2 5 0.59 3.33 1.21
13 INT51089 Negative_regulation of PRMT1 3 0.24 1.18 0.98
14 INT247262 Negative_regulation of Positive_regulation of Mecp2 1 0.42 0.85 0.8
15 INT318962 Negative_regulation of Gene_expression of Mecp2 2 0.43 0.5 0.7
16 INT183395 Localization of Mecp2 4 0.75 1.76 0.69
17 INT280463 Binding of Mecp2 3 0.37 4 0.63
18 INT307096 Regulation of Prmt1 1 0.01 0.92 0.63
19 INT307095 Negative_regulation of Regulation of Prmt1 1 0.02 0.93 0.63
20 INT247256 Negative_regulation of Phosphorylation of Mecp2 1 0.57 0.63 0.52
21 INT247259 Positive_regulation of Gene_expression of Mecp2 1 0.68 0.13 0.46
22 INT280468 Positive_regulation of Localization of Mecp2 3 0.50 1.76 0.45
23 INT318964 Negative_regulation of Localization of Mecp2 1 0.43 0.53 0.43
24 INT51090 Gene_expression of PRMT1 1 0.59 0.27 0.41
25 INT280462 Positive_regulation of Phosphorylation of Mecp2 1 0.12 1.69 0.37
26 INT135356 Positive_regulation of Binding of Mecp2 1 0.50 0.1 0.36
27 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29
28 INT248208 Phosphorylation of Mecp2 3 0.82 1.17 0.26
29 INT156586 Gene_expression of Hst1 1 0.59 0.79 0.22
30 INT247260 Regulation of Gene_expression of Mecp2 1 0.60 0.06 0.21
31 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05
32 INT332918 Localization of Suv39h1 1 0.73 0.11 0.03
33 INT348609 Negative_regulation of EZH2 1 0.29 1.33 0.03
34 INT348611 Localization of EZH2 1 0.50 0.35 0.03
35 INT342085 Positive_regulation of Ehmt1 1 0.01 0.4 0
36 INT320943 Negative_regulation of Phosphorylation of Mecp2 1 0.43 0.33 0
37 INT339087 Binding of Ezh2 1 0.37 1.14 0
38 INT348622 Binding of EZH2 1 0.21 0.39 0
39 INT301444 Positive_regulation of Carm1 1 0.04 0 0
40 INT156731 Binding of PRMT1 1 0.32 0.14 0
41 INT304050 Gene_expression of SUZ12 1 0.54 6.53 0
42 INT301437 Regulation of Carm1 1 0.02 0.06 0
43 INT348618 Gene_expression of EZH2 1 0.51 2.32 0
44 INT225404 Binding of Prmt1 1 0.14 0 0
45 INT342075 Negative_regulation of Ehmt1 1 0.01 0.69 0
46 INT320939 Transcription of Mecp2 1 0.69 0.2 0
47 INT328132 Regulation of Mecp2 1 0.40 1 0
48 INT320952 Regulation of Gene_expression of Mecp2 1 0.45 0.87 0
49 INT348612 Regulation of Gene_expression of EZH2 1 0.30 0.65 0
50 INT320949 Negative_regulation of Binding of Mecp2 1 0.43 0.21 0
51 INT225388 Binding of Carm1 1 0.17 0 0
52 INT339090 Positive_regulation of Ezh2 1 0.47 0.82 0
53 INT348624 Positive_regulation of EZH2 1 0.31 0.42 0
54 INT304070 Regulation of SUZ12 1 0.22 1 0
55 INT338716 Negative_regulation of SUZ12 1 0.08 0.78 0
56 INT339091 Positive_regulation of Gene_expression of Ezh2 1 0.70 11.65 0
57 INT339095 Negative_regulation of Gene_expression of Ezh2 1 0.59 4.48 0
58 INT339089 Regulation of Gene_expression of Ezh2 1 0.45 3.76 0
59 INT320950 Positive_regulation of Gene_expression of Mecp2 1 0.50 1.24 0
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