GO:0016575

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Name histone deacetylation
Categary Process
Go Slim No
Go Link GO:0016575
Unique Molecular Interactions 202
Total Molecular Interactions 262
Total Single Events 1826
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone deacetylation. They are ordered first by their pain relevance and then by number of times they were reported for histone deacetylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
2 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
3 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
4 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
5 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
6 INT224823 CTBS Regulation of SALL1 1 0.14 0.53 0.66
7 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
8 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
9 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
10 INT333893 Negative_regulation of HDAC9 Negative_regulation of Gene_expression of TNF 1 0.09 1.03 0.34
11 INT239558 Binding of CXCR2 and Hopx 1 0.06 0.44 0.31
12 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
13 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
14 INT346957 HDAC9 Positive_regulation of Gene_expression of GSR 1 0.03 1.28 0.27
15 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
16 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
17 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
18 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
19 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
20 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23
21 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
22 INT283948 SALL1 Positive_regulation of Positive_regulation of Ptgfrn 1 0.00 0.21 0.22
23 INT28722 Binding of T2 and Hdac11 1 0.11 0.14 0.18
24 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
25 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
26 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
27 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
28 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
29 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
30 INT239557 Binding of MYC and Hopx 1 0.14 0 0.14
31 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
32 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
33 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
34 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
35 INT200304 Hdac2 Negative_regulation of Rorb 1 0.00 0 0.12
36 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
37 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
38 INT200306 Hdac1 Negative_regulation of Rorb 1 0.00 0 0.12
39 INT200332 Binding of Rcor2 and Hdac1 1 0.15 0.3 0.12
40 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
41 INT28723 Negative_regulation of Binding of T2 and Hdac11 1 0.10 0.08 0.1
42 INT201618 Uvbi1 Positive_regulation of Phb 1 0.04 0.28 0.09
43 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
44 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
45 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
46 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08
47 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
48 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
49 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07
50 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
51 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
52 INT331790 Binding of gr and Hdac2 1 0.01 0.74 0.07
53 INT331791 Akt1 Negative_regulation of Hdac2 1 0.03 0.8 0.07
54 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
55 INT331798 Regulation of Binding of gr and Hdac2 1 0.02 0.75 0.07
56 INT277615 Positive_regulation of Binding of ZNF238 and Hdac3 1 0.38 0.06 0.07
57 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
58 INT277614 Binding of ZNF238 and Hdac3 1 0.29 0.06 0.07
59 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07
60 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
61 INT339979 Binding of PRDX2 and HDAC9 1 0.02 0.16 0.05
62 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
63 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
64 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
65 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
66 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
67 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
68 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
69 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
70 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
71 INT319171 Binding of Cgn and Hdac1 1 0.00 0 0
72 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
73 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
74 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
75 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
76 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
77 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
78 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
79 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
80 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
81 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
82 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0
83 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
84 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
85 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0
86 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
87 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0
88 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
89 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
90 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
91 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
92 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
93 INT339977 Positive_regulation of Binding of HDAC3 and HDAC7 1 0.23 0.52 0
94 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
95 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
96 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
97 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0
98 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
99 INT337401 Binding of E2F1 and HDAC1 1 0.07 0 0
100 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
101 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
102 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
103 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
104 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0
105 INT332896 Binding of Hdac3 and Ncor1 1 0.31 1.38 0
106 INT339978 Binding of HDAC3 and HDAC7 1 0.17 1.04 0
107 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
108 INT332878 Hdac3 Negative_regulation of Gene_expression of Arntl 1 0.42 0.17 0
109 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
110 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
111 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
112 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
113 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
114 INT355201 Binding of HDAC9 and Gopc 1 0.01 0.06 0
115 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
116 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
117 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0
118 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0
119 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
120 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0
121 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0
122 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
123 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
124 INT301470 Binding of Smyd2 and Hdac1 1 0.35 0.31 0
125 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
126 INT332892 Ncor1 Positive_regulation of Hdac3 1 0.45 0.18 0
127 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
128 INT332879 Negative_regulation of Ncor1 Positive_regulation of Hdac3 1 0.28 0.18 0
129 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
130 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0
131 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
132 INT177783 Binding of HDAC1 and PCNA 1 0.09 0.5 0
133 INT233117 Binding of SIRT2 and PAMR1 1 0.00 0 0
134 INT200724 HDAC9 Positive_regulation of TP53 1 0.36 0.27 0
135 INT333684 Binding of Hr and Hdac1 1 0.19 0.56 0
136 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
137 INT233118 Binding of SIRT2 and AICDA 1 0.00 0.21 0
138 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
139 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
140 INT289529 Lep Regulation of Sirt1 1 0.28 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone deacetylation. They are ordered first by their pain relevance and then by number of times they were reported in histone deacetylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9
2 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
3 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36
4 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
5 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
6 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
7 INT97692 Positive_regulation of HDAC9 17 0.45 14.88 5.11
8 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
9 INT224826 Gene_expression of SALL1 1 0.55 1.94 2.57
10 INT133648 Regulation of HDAC9 14 0.60 10.01 2.18
11 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
12 INT180134 Gene_expression of SIRT2 70 0.11 6.95 1.84
13 INT191154 Binding of HDAC9 20 0.36 14.12 1.83
14 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
15 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
16 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
17 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
18 INT332792 Positive_regulation of Gene_expression of HDAC9 5 0.45 4.61 1.44
19 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
20 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
21 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23
22 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
23 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
24 INT68339 Gene_expression of HDAC2 3 0.51 1.71 1.1
25 INT239527 Gene_expression of Hopx 1 0.26 0.5 1.06
26 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
27 INT333907 Positive_regulation of HDAC1 4 0.32 3.07 1.03
28 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
29 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
30 INT317791 Localization of HDAC2 2 0.50 2.31 0.99
31 INT180136 Localization of SIRT2 15 0.12 1.42 0.88
32 INT224830 Positive_regulation of Gene_expression of SALL1 1 0.41 0.64 0.81
33 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
34 INT200250 Binding of Hdac2 6 0.22 2.97 0.76
35 INT70423 Binding of HDAC3 1 0.01 0.36 0.75
36 INT284955 Localization of HDAC1 2 0.47 1.71 0.74
37 INT180139 Protein_catabolism of SIRT2 11 0.14 1.1 0.72
38 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7
39 INT272886 Negative_regulation of Gene_expression of Hdac2 4 0.23 4.63 0.69
40 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
41 INT224827 Regulation of SALL1 2 0.37 3.36 0.62
42 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5
43 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49
44 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
45 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
46 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
47 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
48 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
49 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
50 INT180142 Negative_regulation of SIRT2 10 0.07 0.19 0.41
51 INT85854 Binding of SALL1 5 0.36 1.4 0.41
52 INT180138 Negative_regulation of Gene_expression of SIRT2 2 0.07 0.19 0.41
53 INT333915 Negative_regulation of Binding of HDAC9 1 0.21 0.83 0.41
54 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
55 INT196927 Binding of Hdac1 9 0.36 2.31 0.36
56 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
57 INT333916 Negative_regulation of HDAC2 2 0.18 1.38 0.36
58 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
59 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
60 INT198170 Positive_regulation of SALL1 4 0.49 1.5 0.32
61 INT272882 Positive_regulation of Binding of Hdac2 2 0.20 1.12 0.32
62 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
63 INT333912 Regulation of Positive_regulation of HDAC9 1 0.19 0.63 0.31
64 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
65 INT177856 Negative_regulation of Gene_expression of HDAC2 1 0.19 0.12 0.3
66 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
67 INT196917 Gene_expression of Hdac1 15 0.71 3.66 0.28
68 INT180144 Binding of SIRT2 57 0.06 1.29 0.27
69 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
70 INT234466 Regulation of Negative_regulation of HDAC9 2 0.25 1.82 0.26
71 INT312887 Gene_expression of Hdac6 1 0.60 1.28 0.25
72 INT234461 Negative_regulation of Gene_expression of HDAC9 5 0.24 2.74 0.24
73 INT312883 Regulation of Regulation of Hdac6 1 0.40 0.38 0.24
74 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
75 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
76 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
77 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
78 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
79 INT123265 Negative_regulation of SALL1 3 0.18 0.78 0.19
80 INT175663 Positive_regulation of SIRT2 56 0.14 3.58 0.17
81 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
82 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
83 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
84 INT133646 Positive_regulation of Regulation of HDAC9 1 0.49 0.83 0.17
85 INT239531 Localization of Hopx 1 0.24 0.06 0.16
86 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
87 INT266991 Regulation of Hdac2 2 0.07 0.74 0.15
88 INT312881 Positive_regulation of Hdac6 1 0.45 0.67 0.15
89 INT233124 Positive_regulation of Gene_expression of SIRT2 17 0.04 0.16 0.14
90 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
91 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
92 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
93 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
94 INT337484 Gene_expression of HDAC3 2 0.37 0.15 0.13
95 INT341562 Negative_regulation of Gene_expression of HDAC3 1 0.23 0.05 0.13
96 INT239529 Binding of Hopx 1 0.14 0.28 0.13
97 INT196934 Negative_regulation of Hdac1 4 0.39 1.41 0.11
98 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
99 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
100 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
101 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
102 INT331783 Regulation of Negative_regulation of Hdac1 1 0.04 0.98 0.11
103 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
104 INT239532 Phosphorylation of Hopx 1 0.27 0.17 0.1
105 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
106 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
107 INT28720 Binding of Hdac11 1 0.26 0.07 0.09
108 INT331786 Negative_regulation of Binding of Hdac2 1 0.11 1.2 0.08
109 INT284980 Positive_regulation of Protein_catabolism of HDAC2 1 0.20 0.81 0.08
110 INT284976 Protein_catabolism of HDAC2 1 0.28 0.8 0.08
111 INT346968 Positive_regulation of Transcription of HDAC9 1 0.22 0.21 0.07
112 INT346969 Transcription of HDAC9 1 0.23 0.21 0.07
113 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
114 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
115 INT224825 Regulation of Gene_expression of SALL1 1 0.37 0.07 0.07
116 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
117 INT331784 Negative_regulation of Positive_regulation of Hdac2 1 0.11 0.52 0.05
118 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
119 INT191153 Negative_regulation of Negative_regulation of HDAC9 1 0.09 0.57 0.05
120 INT312877 Positive_regulation of Negative_regulation of Hdac6 1 0.45 0 0.05
121 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
122 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
123 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
124 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
125 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
126 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04
127 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
128 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
129 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
130 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
131 INT326227 Phosphorylation of HDAC9 1 0.22 2.32 0.03
132 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
133 INT312888 Phosphorylation of Hdac6 1 0.73 0 0.03
134 INT328554 Regulation of HDAC1 1 0.26 1.12 0.03
135 INT331778 Regulation of Phosphorylation of Hdac2 1 0.11 0.49 0.03
136 INT331787 Phosphorylation of Hdac2 1 0.20 0.49 0.03
137 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
138 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
139 INT204349 Regulation of SIRT1 8 0.61 1.99 0
140 INT256134 Localization of Sirt1 5 0.50 2.99 0
141 INT233125 Positive_regulation of Positive_regulation of SIRT2 4 0.04 0 0
142 INT277595 Localization of Hdac1 4 0.73 0.81 0
143 INT204353 Transcription of SIRT1 3 0.68 0.67 0
144 INT277612 Localization of HDAC9 3 0.45 0.55 0
145 INT180140 Regulation of SIRT2 3 0.04 0 0
146 INT233126 Regulation of Gene_expression of SIRT2 2 0.03 0 0
147 INT180146 Positive_regulation of Binding of SIRT2 2 0.08 0 0
148 INT265379 Positive_regulation of Binding of HDAC9 2 0.19 1.06 0
149 INT265371 Binding of Hdac3 2 0.27 0.94 0
150 INT261751 Regulation of Hdac1 2 0.41 0 0
151 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
152 INT312873 Negative_regulation of Gene_expression of Hdac6 1 0.38 0 0
153 INT279810 Negative_regulation of Positive_regulation of SALL1 1 0.03 0.07 0
154 INT233120 Regulation of Binding of SIRT2 1 0.03 0 0
155 INT350509 Phosphorylation of HDAC1 1 0.25 0.62 0
156 INT265375 Negative_regulation of Hdac3 1 0.36 0.78 0
157 INT337478 Binding of HDAC2 1 0.14 0.07 0
158 INT312885 Binding of Hdac6 1 0.43 0 0
159 INT319154 Transcription of Hdac1 1 0.66 0 0
160 INT319156 Negative_regulation of Gene_expression of Hdac1 1 0.39 0.22 0
161 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
162 INT289569 Transcription of Sirt1 1 0.71 0.25 0
163 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
164 INT312874 Regulation of Phosphorylation of Hdac6 1 0.40 0 0
165 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
166 INT277596 Phosphorylation of Hdac1 1 0.61 0.59 0
167 INT300287 Localization of Sirt1 1 0.66 1.46 0
168 INT243078 Gene_expression of Phb 1 0.42 0.09 0
169 INT326229 Regulation of Phosphorylation of HDAC9 1 0.07 0.48 0
170 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
171 INT289583 Regulation of Transcription of Sirt1 1 0.27 0.25 0
172 INT326233 Negative_regulation of Phosphorylation of HDAC9 1 0.11 0 0
173 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
174 INT319169 Negative_regulation of Transcription of Hdac1 1 0.54 0 0
175 INT312876 Negative_regulation of Transcription of Hdac6 1 0.38 0 0
176 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
177 INT277577 Transcription of Hdac4 1 0.69 0 0
178 INT301188 Regulation of Positive_regulation of SIRT2 1 0.03 1.05 0
179 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
180 INT355198 Positive_regulation of Localization of Hdac1 1 0.19 0.48 0
181 INT350933 Gene_expression of Hdac11 1 0.33 0.12 0
182 INT180143 Phosphorylation of SIRT2 1 0.13 0 0
183 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
184 INT289594 Regulation of Regulation of Sirt1 1 0.45 0.15 0
185 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
186 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
187 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
188 INT355200 Regulation of Gene_expression of HDAC9 1 0.14 1.77 0
189 INT312875 Transcription of Hdac6 1 0.61 0 0
190 INT276275 Positive_regulation of Localization of SIRT2 1 0.04 0 0
191 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
192 INT276271 Transcription of SIRT2 1 0.05 0 0
193 INT319162 Regulation of Gene_expression of Hdac1 1 0.56 0 0
194 INT319152 Positive_regulation of Gene_expression of Hdac1 1 0.46 0 0
195 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
196 INT337460 Positive_regulation of Gene_expression of HDAC3 1 0.17 0.1 0
197 INT276273 Positive_regulation of Protein_catabolism of SIRT2 1 0.04 0.06 0
198 INT204331 Binding of SIRT1 1 0.47 0.39 0
199 INT312878 Protein_catabolism of Hdac6 1 0.88 0 0
200 INT311329 Positive_regulation of Hdac1 1 0.19 0.14 0
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