GO:0016592

From wiki-pain
Jump to: navigation, search
Name mediator complex
Categary Component
Go Slim No
Go Link GO:0016592
Unique Molecular Interactions 32
Total Molecular Interactions 47
Total Single Events 154
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mediator complex. They are ordered first by their pain relevance and then by number of times they were reported for mediator complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
2 INT153657 PRKCA Negative_regulation of MED23 1 0.01 0.22 0.46
3 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
4 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
5 INT297964 Binding of CDK8 and MAP3K11 1 0.26 0.29 0.07
6 INT297969 Positive_regulation of Binding of CDK8 and MAP3K11 1 0.35 0.29 0.07
7 INT297971 Positive_regulation of Binding of CDK8 and MAPK1 1 0.22 0.3 0.07
8 INT297963 Binding of CDK8 and MAPK1 1 0.16 0.29 0.07
9 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
10 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
11 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
12 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
13 INT225630 MED23 Positive_regulation of Localization of D0Nrs1 1 0.03 0.17 0
14 INT225641 Binding of MED23 and Acp5 1 0.39 0.14 0
15 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
16 INT177286 Binding of CXADR and MED1 1 0.27 0 0
17 INT225633 Binding of STL and MED23 1 0.02 0 0
18 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
19 INT225634 Binding of TARBP2 and MED23 1 0.04 0.15 0
20 INT225628 MED23 Positive_regulation of D0Nrs1 1 0.03 0.16 0
21 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
22 INT225625 Binding of MED23 and Ncoa6 1 0.40 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mediator complex. They are ordered first by their pain relevance and then by number of times they were reported in mediator complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86071 Negative_regulation of Med15 3 0.43 1.19 3.38
2 INT86072 Binding of Med15 1 0.47 0.23 0.9
3 INT153673 Negative_regulation of MED23 1 0.02 0.27 0.42
4 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
5 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
6 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
7 INT297997 Negative_regulation of CDK8 1 0.49 1.79 0.28
8 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
9 INT297976 Positive_regulation of CDK8 1 0.42 1.79 0.13
10 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
11 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
12 INT190468 Gene_expression of CDK8 5 0.65 4.74 0
13 INT307189 Localization of Med1 3 0.53 0.32 0
14 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
15 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
16 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
17 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
18 INT307188 Transcription of Med1 1 0.48 0.7 0
19 INT308399 Gene_expression of MED23 1 0.58 1.26 0
20 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
21 INT177320 Binding of MED1 1 0.25 0 0
22 INT225457 Binding of Med1 1 0.35 0.28 0
23 INT308403 Negative_regulation of Gene_expression of MED23 1 0.42 1.31 0
24 INT297974 Negative_regulation of Gene_expression of CDK8 1 0.49 0.54 0
25 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
26 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
27 INT225468 Binding of MED23 1 0.47 0 0
28 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
29 INT308401 Positive_regulation of MED23 1 0.45 1.27 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox