GO:0016605

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Name PML body
Categary Component
Go Slim No
Go Link GO:0016605
Unique Molecular Interactions 607
Total Molecular Interactions 762
Total Single Events 5399
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for PML body. They are ordered first by their pain relevance and then by number of times they were reported for PML body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
3 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
4 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
5 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
6 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
7 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
8 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
9 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
10 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
11 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
12 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
13 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
14 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
15 INT328501 Sumo1 Negative_regulation of Gene_expression of Pglyrp1 1 0.00 1.54 0.83
16 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
17 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
18 INT16048 MAX Positive_regulation of SLC25A4 1 0.50 0 0.71
19 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
20 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
21 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
22 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
23 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
24 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
25 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
26 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
27 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
28 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
29 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
30 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48
31 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48
32 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
33 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
34 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
35 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
36 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
37 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
38 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
39 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
40 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
41 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
42 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
43 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
44 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
45 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
46 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
47 INT129293 OPRM1 Positive_regulation of Phosphorylation of IKBKE 1 0.05 0.28 0.35
48 INT167551 Binding of MECP2 and SP3 1 0.01 0.06 0.35
49 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
50 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
51 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
52 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
53 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
54 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
55 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
56 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
57 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
58 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
59 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
60 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
61 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
62 INT328500 Sumo1 Positive_regulation of Negative_regulation of Cebpz 1 0.11 1.06 0.29
63 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
64 INT18499 Binding of SUMO1 and SEC1 1 0.12 0 0.28
65 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
66 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
67 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
68 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
69 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
70 INT328499 Binding of Cebpz and Sumo1 1 0.08 0.84 0.27
71 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
72 INT96790 SP3 Positive_regulation of GDF15 1 0.20 0.26 0.27
73 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
74 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
75 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
76 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
77 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
78 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
79 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
80 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
81 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
82 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
83 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
84 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
85 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
86 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
87 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21
88 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
89 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
90 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
91 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
92 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2
93 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
94 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
95 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
96 INT88698 Binding of Max and Cpm 1 0.00 0.27 0.18
97 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
98 INT88702 Binding of CPM and Max 1 0.01 0.27 0.18
99 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
100 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
101 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
102 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
103 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17
104 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
105 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
106 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
107 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
108 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
109 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
110 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
111 INT171871 Binding of FAS and Sumo1 1 0.02 1.43 0.16
112 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
113 INT171870 Binding of Ltbr and Sumo1 1 0.00 1.44 0.16
114 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
115 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
116 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
117 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
118 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
119 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
120 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
121 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
122 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
123 INT245333 ATR Negative_regulation of Protein_catabolism of DCD 1 0.10 0.93 0.14
124 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
125 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
126 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
127 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
128 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
129 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
130 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
131 INT276064 Src Regulation of Positive_regulation of Rpa1 1 0.02 0.18 0.11
132 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
133 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
134 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1
135 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1
136 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1
137 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
138 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
139 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
140 INT276041 Positive_regulation of Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 0.01 0 0.1
141 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
142 INT245182 Binding of SPINK1 and TCF7L2 1 0.39 2.05 0.1
143 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
144 INT210988 Binding of SP3 and PKDREJ 1 0.01 0.17 0.1
145 INT210994 Binding of SEA and SP3 1 0.00 0.17 0.1
146 INT276039 Positive_regulation of Car2 Positive_regulation of Positive_regulation of Rpa1 1 0.04 0 0.09
147 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
148 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
149 INT292623 ISG20 Positive_regulation of Gene_expression of IL9 1 0.10 0 0.09
150 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
151 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
152 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
153 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
154 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
155 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
156 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
157 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
158 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
159 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
160 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
161 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
162 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
163 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
164 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
165 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
166 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
167 INT273107 Bdnf Regulation of Positive_regulation of Mtor 1 0.26 0.09 0.07
168 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
169 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
170 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
171 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
172 INT317426 Binding of CSF2 and PML 1 0.08 1.25 0.06
173 INT338902 Binding of MAX and MYC 1 0.02 0.23 0.06
174 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
175 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
176 INT346456 TLR3 Positive_regulation of IKBKE 1 0.02 0.45 0.06
177 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
178 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
179 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
180 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
181 INT273098 Binding of Bdnf and Positive_regulation of Mtor 1 0.47 0 0.06
182 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
183 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
184 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
185 INT346454 TICAM1 Positive_regulation of IKBKE 1 0.01 0.45 0.06
186 INT245329 ATR Negative_regulation of DCD 1 0.10 0.91 0.05
187 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
188 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
189 INT245331 ATR Regulation of IL1B 1 0.03 0.91 0.05
190 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
191 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
192 INT351010 ISG20 Positive_regulation of Transcription of IL2 1 0.31 0.46 0.05
193 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
194 INT273096 Mtor Positive_regulation of Gene_expression of Grip2 1 0.05 0.07 0.05
195 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
196 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
197 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
198 INT245330 ATR Regulation of TNF 1 0.04 0.9 0.05
199 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
200 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for PML body. They are ordered first by their pain relevance and then by number of times they were reported in PML body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT54294 Localization of Spnb4 9 0.78 0 18.64
3 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
4 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
5 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
6 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
7 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58
8 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
9 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
10 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
11 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
12 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
13 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
14 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
15 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
16 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
17 INT121494 Transcription of TERT 64 0.69 10.03 5.55
18 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
19 INT60585 Regulation of TP53 59 0.59 54.55 5.21
20 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
21 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
22 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
23 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
24 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
25 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
26 INT54297 Regulation of Localization of Spnb4 3 0.44 0 4.36
27 INT15802 Positive_regulation of Gene_expression of ISG20 16 0.42 8.16 4.03
28 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
29 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
30 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
31 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
32 INT192676 Binding of PTEN 14 0.46 10.58 3.06
33 INT8103 Binding of TP53 46 0.44 40.2 2.96
34 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
35 INT56589 Positive_regulation of Localization of Spnb4 2 0.49 0 2.81
36 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
37 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
38 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
39 INT89336 Binding of SP3 6 0.47 1.75 2.63
40 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
41 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
42 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
43 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
44 INT55952 Transcription of TP53 16 0.61 12.14 2.36
45 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
46 INT56658 Gene_expression of Spnb4 7 0.58 5.6 2.22
47 INT54295 Negative_regulation of Localization of Spnb4 2 0.57 0 2.21
48 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
49 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
50 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
51 INT92415 Positive_regulation of Max 4 0.67 1.13 2.1
52 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
53 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
54 INT15799 Positive_regulation of ISG20 18 0.38 9.78 2.01
55 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
56 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
57 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
58 INT56656 Positive_regulation of Spnb4 3 0.49 1.09 1.92
59 INT65855 Localization of TP53 18 0.76 17.08 1.89
60 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
61 INT139459 Negative_regulation of MAX 6 0.57 0.32 1.79
62 INT56657 Negative_regulation of Positive_regulation of Spnb4 1 0.41 0 1.71
63 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
64 INT97062 Binding of PML 10 0.41 11.63 1.65
65 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
66 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
67 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
68 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
69 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
70 INT18503 Binding of SUMO1 7 0.27 6.21 1.48
71 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
72 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
73 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
74 INT58581 Binding of RPA1 8 0.44 1.68 1.44
75 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
76 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
77 INT166764 Localization of Mtor 2 0.75 1.28 1.42
78 INT172953 Binding of Trp53 33 0.37 20.76 1.41
79 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
80 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
81 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
82 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
83 INT145221 Binding of Tp53 10 0.37 8.59 1.37
84 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
85 INT147607 Binding of TERT 16 0.48 12.36 1.31
86 INT189736 Regulation of TERT 22 0.40 3.58 1.29
87 INT63905 Regulation of RB1 13 0.62 12.67 1.28
88 INT38916 Positive_regulation of Tert 3 0.33 1.92 1.28
89 INT260114 Regulation of ISG20 5 0.37 4.98 1.27
90 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
91 INT260111 Localization of ISG20 6 0.41 3.46 1.25
92 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
93 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
94 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
95 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
96 INT174156 Localization of Trp53 16 0.72 13.52 1.18
97 INT82547 Negative_regulation of Gene_expression of ISG20 7 0.29 3.04 1.18
98 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
99 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
100 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
101 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
102 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
103 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
104 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
105 INT238596 Gene_expression of Sumo1 1 0.44 0.25 1.02
106 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
107 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
108 INT167702 Negative_regulation of Rpa1 3 0.06 1.16 0.96
109 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
110 INT133608 Regulation of Daxx 1 0.16 0.28 0.93
111 INT171851 Gene_expression of Sumo1 13 0.30 10.7 0.89
112 INT54296 Regulation of Spnb4 3 0.44 2.06 0.89
113 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
114 INT174516 Regulation of Gene_expression of ISG20 6 0.27 4.2 0.85
115 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
116 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
117 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
118 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
119 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
120 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
121 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
122 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
123 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
124 INT144880 Negative_regulation of DAXX 4 0.23 2.15 0.73
125 INT47481 Localization of SUMO1 1 0.01 0 0.73
126 INT262726 Localization of PML 6 0.57 7.13 0.72
127 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
128 INT133603 Gene_expression of Daxx 1 0.28 0.27 0.7
129 INT133606 Regulation of Gene_expression of Daxx 1 0.16 0.27 0.7
130 INT276010 Regulation of Positive_regulation of Rpa1 1 0.06 0.72 0.7
131 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
132 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
133 INT169931 Localization of Rb1 6 0.70 4.79 0.65
134 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
135 INT129296 Phosphorylation of IKBKE 1 0.35 0.54 0.63
136 INT167701 Phosphorylation of Rpa1 1 0.01 0.16 0.61
137 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
138 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
139 INT161322 Localization of PTEN 9 0.73 5.65 0.57
140 INT160777 Transcription of CHEK2 1 0.52 1.03 0.57
141 INT11455 Regulation of MAX 6 0.44 2.49 0.56
142 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
143 INT182835 Phosphorylation of Crebbp 2 0.26 0.78 0.54
144 INT92349 Positive_regulation of MAX 3 0.41 1.46 0.53
145 INT182836 Positive_regulation of Crebbp 2 0.21 0.76 0.53
146 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
147 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
148 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
149 INT189756 Positive_regulation of Phosphorylation of TERT 1 0.28 0.2 0.5
150 INT189728 Phosphorylation of TERT 1 0.34 0.2 0.5
151 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
152 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
153 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
154 INT135612 Regulation of IKBKE 1 0.21 1.24 0.48
155 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
156 INT135614 Positive_regulation of IKBKE 1 0.23 1.26 0.47
157 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
158 INT155088 Positive_regulation of DAXX 1 0.22 1.27 0.45
159 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
160 INT203478 Gene_expression of Crebbp 3 0.46 2.15 0.44
161 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
162 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
163 INT256035 Positive_regulation of Sumo1 2 0.03 1.23 0.41
164 INT98969 Regulation of Binding of SP3 1 0.26 0 0.41
165 INT260121 Regulation of Localization of ISG20 1 0.14 0.81 0.41
166 INT194993 Binding of RB1 15 0.37 10.96 0.4
167 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
168 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
169 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
170 INT41126 Localization of Rb1 2 0.61 0.78 0.39
171 INT89333 Negative_regulation of SP3 1 0.38 0.77 0.39
172 INT89335 Negative_regulation of Binding of SP3 1 0.38 0.77 0.39
173 INT136180 Binding of MTOR 9 0.35 5.01 0.38
174 INT58580 Positive_regulation of Binding of RPA1 2 0.43 0 0.38
175 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
176 INT158641 Positive_regulation of CHEK2 5 0.35 4.15 0.37
177 INT98960 Positive_regulation of Binding of SP3 1 0.67 0 0.37
178 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
179 INT275992 Positive_regulation of Positive_regulation of Rpa1 1 0.05 0.31 0.36
180 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
181 INT162983 Binding of Daxx 1 0.10 0.1 0.36
182 INT130043 Positive_regulation of Daxx 1 0.51 0.54 0.35
183 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
184 INT189760 Negative_regulation of Negative_regulation of TERT 1 0.24 0.11 0.34
185 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
186 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
187 INT189739 Negative_regulation of Regulation of TERT 1 0.18 0.17 0.32
188 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
189 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
190 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
191 INT249123 Binding of Mtor 9 0.36 0.57 0.3
192 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
193 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
194 INT17138 Positive_regulation of Skil 2 0.35 0.59 0.3
195 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
196 INT245337 Gene_expression of ATR 3 0.27 2.06 0.29
197 INT86708 Negative_regulation of SUMO1 3 0.18 1.71 0.28
198 INT41720 Positive_regulation of Gene_expression of MTOR 2 0.49 1.54 0.28
199 INT41722 Positive_regulation of Negative_regulation of MTOR 1 0.45 0.73 0.28
200 INT336951 Positive_regulation of Binding of PML 1 0.09 2.02 0.28
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