GO:0016705

From wiki-pain
Jump to: navigation, search
Name oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Categary Function
Go Slim No
Go Link GO:0016705
Unique Molecular Interactions 248
Total Molecular Interactions 290
Total Single Events 2952
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. They are ordered first by their pain relevance and then by number of times they were reported for oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
2 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
3 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
4 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
5 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
6 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
7 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09
8 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08
9 INT77083 Das Negative_regulation of Cyp2e1 1 0.20 0.59 1.06
10 INT154237 Binding of CYP2D6 and Ugt2b7 1 0.41 0.75 1
11 INT53750 Cyp2e1 Positive_regulation of RYBP 1 0.14 0.44 0.99
12 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
13 INT56274 RYBP Negative_regulation of Cyp2e1 1 0.01 0.17 0.9
14 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9
15 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
16 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86
17 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81
18 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
19 INT90959 PPIG Regulation of CYP2C9 1 0.43 0 0.75
20 INT88921 Positive_regulation of CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
21 INT88922 CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
22 INT92370 Binding of CYP2B6 and CYP2D6 1 0.21 0 0.73
23 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
24 INT28184 Binding of CYP1A2 and CYP2D6 1 0.00 0 0.7
25 INT76026 Binding of Cyp2e1 and Cyp3a11 1 0.28 0.42 0.64
26 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63
27 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62
28 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
29 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
30 INT149690 M1 Negative_regulation of CYP2C8 1 0.19 0.05 0.46
31 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
32 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
33 INT103028 Calca Positive_regulation of Gene_expression of Ptgis 1 0.17 0.58 0.44
34 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4
35 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4
36 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
37 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
38 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
39 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
40 INT159903 Binding of CYP2C8 and CYP2C9 1 0.42 0.22 0.35
41 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
42 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
43 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
44 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
45 INT207355 ZNF398 Regulation of CYP27A1 1 0.00 0 0.31
46 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
47 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
48 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
49 INT59684 Binding of Gmfb and Cyp2c6 1 0.00 0 0.29
50 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29
51 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29
52 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
53 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28
54 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
55 INT142450 B4GALNT1 Regulation of Gene_expression of PTGIS 1 0.02 0.24 0.27
56 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27
57 INT169146 CYP2D6 Regulation of CYP3A 1 0.22 0 0.27
58 INT169145 Regulation of CYP2D6 Regulation of CYP3A 1 0.22 0 0.27
59 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27
60 INT114230 NR1I2 Positive_regulation of Positive_regulation of CYP2C9 1 0.13 0.61 0.27
61 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
62 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
63 INT19839 Positive_regulation of Binding of Ptgis and Tbxa2r 1 0.00 0.2 0.26
64 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
65 INT130678 CYP2C9 Regulation of Cyp1a2 1 0.06 0 0.26
66 INT130677 CYP2C9 Regulation of Binding of Ugt2b7 1 0.18 0 0.26
67 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
68 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
69 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
70 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25
71 INT19840 Binding of Ptgis and Tbxa2r 1 0.00 0.2 0.25
72 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
73 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24
74 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
75 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
76 INT339570 Gene_expression of Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.5 0.23
77 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
78 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22
79 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22
80 INT100823 Cyp2e1 Positive_regulation of Ros1 1 0.35 1.22 0.22
81 INT142446 Regulation of CPOX Regulation of Gene_expression of PTGIS 1 0.10 0.26 0.22
82 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21
83 INT142448 TNF Positive_regulation of Localization of PTGIS 1 0.35 0.28 0.21
84 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2
85 INT179689 Binding of CYP4F3 and DAK 1 0.00 1.23 0.2
86 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
87 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18
88 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18
89 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18
90 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18
91 INT326460 NR1I2 Regulation of Cyp4f18 1 0.01 0.72 0.18
92 INT180560 Binding of COMP and CYP27A1 1 0.12 0.47 0.18
93 INT121380 Casr Positive_regulation of Positive_regulation of Cyp3a11 1 0.15 0.25 0.18
94 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18
95 INT207339 TBXA2R Negative_regulation of Negative_regulation of CYP27A1 1 0.01 0 0.17
96 INT207354 TBXA2R Regulation of Gene_expression of CYP27A1 1 0.01 0 0.17
97 INT207342 PTGDS Negative_regulation of Gene_expression of CYP27A1 1 0.02 0 0.17
98 INT207351 ZNF398 Negative_regulation of CYP27A1 1 0.00 0 0.17
99 INT104379 Gh1 Regulation of CYP2D6 1 0.07 0 0.17
100 INT207340 PTGER2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0.17
101 INT75036 Slc6a14 Negative_regulation of Cyp11b1 1 0.00 0.17 0.17
102 INT207357 TBXA2R Positive_regulation of CYP27A1 1 0.01 0 0.16
103 INT207349 TBXA2R Regulation of CYP27A1 1 0.01 0 0.16
104 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16
105 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 0.47 0.06 0.16
106 INT180562 Binding of CYP27A1 and HEYL 1 0.02 0.29 0.16
107 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
108 INT89597 Binding of CPOX and TBXAS1 1 0.04 0.05 0.14
109 INT207335 PTGDS Negative_regulation of Negative_regulation of CYP27A1 1 0.02 0 0.14
110 INT207346 PTGER2 Negative_regulation of Negative_regulation of CYP27A1 1 0.00 0 0.14
111 INT256320 Binding of CYP26A1 and Hapln1 1 0.01 1.27 0.14
112 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13
113 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13
114 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
115 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
116 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13
117 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12
118 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12
119 INT307075 Tbxas1 Negative_regulation of Negative_regulation of PLG 1 0.01 1.22 0.11
120 INT97082 CYP2D6 Regulation of HAGH 1 0.02 0 0.11
121 INT156832 MAPK7 Positive_regulation of Transcription of CYP24A1 1 0.35 0 0.1
122 INT339533 VEGFA Positive_regulation of Gene_expression of CYP2C8 1 0.09 0.57 0.09
123 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09
124 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09
125 INT160159 Gene_expression of CYP2C9 Positive_regulation of HSP90B2P 1 0.13 0.53 0.09
126 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09
127 INT220394 MRXS5 Positive_regulation of Gene_expression of CYP19A1 1 0.00 0.89 0.09
128 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09
129 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09
130 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09
131 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09
132 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09
133 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09
134 INT220412 Cpox Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.9 0.09
135 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09
136 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09
137 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09
138 INT75033 Slc6a14 Negative_regulation of Gene_expression of Cyp11b1 1 0.00 0.08 0.08
139 INT219661 Binding of CYP2D6 and CYP2E1 1 0.30 0.22 0.08
140 INT339534 VEGFA Positive_regulation of CYP2C18 1 0.04 0.57 0.08
141 INT188519 Il1a Positive_regulation of Ptgis 1 0.03 0.08 0.08
142 INT156839 Binding of CYP24A1 and MAPK3 1 0.31 0 0.07
143 INT262219 Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
144 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07
145 INT156830 Binding of CYP24A1 and TRPV6 1 0.32 0 0.07
146 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07
147 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
148 INT156828 Positive_regulation of Binding of CYP24A1 and TRPV6 1 0.42 0 0.07
149 INT262143 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
150 INT262145 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.45 0.06
151 INT323043 Binding of CYP21A1P and HLA-DOA 1 0.04 1.48 0.06
152 INT323042 Binding of CYP21A2 and HLA-DOA 1 0.04 1.49 0.06
153 INT342221 Cyp2e1 Positive_regulation of Gene_expression of TRNAI1 1 0.03 0.22 0.05
154 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05
155 INT218009 AHR Positive_regulation of CYP27B1 1 0.16 0.06 0.05
156 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05
157 INT218010 EE Positive_regulation of CYP27B1 1 0.05 0 0.04
158 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
159 INT262221 Nr1i2 Negative_regulation of Cyp24a1 1 0.27 0.15 0.04
160 INT303026 Gene_expression of MCPH1 Positive_regulation of Gene_expression of Ptgis 1 0.02 0.78 0.04
161 INT218011 AHR Positive_regulation of Transcription of CYP27B1 1 0.16 0 0.04
162 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
163 INT323286 CYP4A11 Positive_regulation of Kcnma1 1 0.01 0.45 0.04
164 INT172912 CYP4A11 Regulation of Prkca 1 0.00 0.05 0.04
165 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04
166 INT187732 Binding of CYP19A1 and Cyp11a1 1 0.01 0.68 0.04
167 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04
168 INT207362 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP27A1 1 0.01 0 0.03
169 INT207356 PTGER2 Regulation of Gene_expression of CYP27A1 1 0.00 0.05 0.03
170 INT262171 Binding of Cyp3a11 and Rare1 1 0.02 0.15 0.03
171 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03
172 INT262217 Casr Regulation of Cyp3a11 1 0.05 0.13 0.03
173 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03
174 INT207361 PTGDS Regulation of Gene_expression of CYP27A1 1 0.01 0.05 0.03
175 INT331157 Ptgis Positive_regulation of Ptgs2 1 0.04 0.77 0.03
176 INT177672 Vmn1r51 Positive_regulation of Localization of Ptgis 1 0.00 0.24 0.03
177 INT199527 Ceacam1 Negative_regulation of CYP27A1 1 0.02 0.06 0.03
178 INT303010 Ptgis Positive_regulation of Rock2 1 0.05 1.23 0.03
179 INT187676 Binding of CYP19A1 and SHBG 1 0.01 0.63 0.03
180 INT133804 Binding of CYP2B6 and CYP19A1 3 0.09 2.26 0
181 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0
182 INT294894 CYP3A4 Negative_regulation of CYP2C19 1 0.08 0.13 0
183 INT262170 Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.4 0
184 INT353189 Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0
185 INT139719 Binding of CYP2C9 and UGT1A6 1 0.19 0.1 0
186 INT259451 Binding of DHCR7 and Cyp11a1 1 0.01 0.3 0
187 INT305779 Binding of CYP4A11 and LRCH2 1 0.00 0 0
188 INT301640 Positive_regulation of Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.03 0.25 0
189 INT262204 Nr1i2 Positive_regulation of Cyp3a11 1 0.33 0.08 0
190 INT242176 AIS Negative_regulation of CYP19A1 1 0.07 0.69 0
191 INT268096 Binding of CYP4F3 and PDSS1 1 0.00 0.35 0
192 INT20322 Binding of CYP1A2 and CYP26A1 1 0.00 0 0
193 INT125642 Cyp2b2 Positive_regulation of Transcription of Cyp2c6 1 0.06 0 0
194 INT44023 Binding of Cyp27b1 and Klk1b27 1 0.00 0.1 0
195 INT125655 Cyp2c6 Positive_regulation of Transcription of Cyp2b2 1 0.06 0 0
196 INT220411 Ptger2 Positive_regulation of Cyp19a1 1 0.09 0.83 0
197 INT187674 FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.24 0 0
198 INT262213 Plec Positive_regulation of Cyp3a11 1 0.02 0 0
199 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0
200 INT199717 2610029G23Rik Regulation of CYP2D6 1 0.02 0.44 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. They are ordered first by their pain relevance and then by number of times they were reported in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91
2 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53
3 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16
4 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
5 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72
6 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
7 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79
8 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39
9 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39
10 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31
11 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12
12 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08
13 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21
14 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17
15 INT47860 Negative_regulation of Cyp1a2 20 0.57 6.06 10
16 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53
17 INT53746 Regulation of Cyp2e1 11 0.62 3.82 9.52
18 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76
19 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
20 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33
21 INT5114 Gene_expression of Ptgis 41 0.50 21.43 8.1
22 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87
23 INT96724 Gene_expression of Cyp3a11 10 0.77 4.82 7.76
24 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53
25 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13
26 INT76025 Positive_regulation of Cyp3a11 20 0.69 5.88 6.91
27 INT43415 Gene_expression of CYP4A11 11 0.56 7.65 5.94
28 INT62579 Negative_regulation of Gene_expression of Cyp2e1 8 0.59 2.95 5.48
29 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
30 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28
31 INT65135 Binding of CYP2C19 17 0.48 1.82 5.2
32 INT19934 Negative_regulation of Ptgis 18 0.32 6.18 5.03
33 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96
34 INT110549 Negative_regulation of CYP2C8 15 0.59 0.54 4.78
35 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73
36 INT65881 Gene_expression of CYP2C19 21 0.76 1.19 4.57
37 INT52088 Binding of Cyp2e1 8 0.48 2.5 4.43
38 INT66242 Gene_expression of Ptgis 15 0.64 6.73 3.84
39 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8
40 INT53395 Positive_regulation of Cyp2c6 6 0.70 0.07 3.73
41 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
42 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
43 INT134694 Binding of CYP27A1 10 0.47 5.61 3.56
44 INT180591 Protein_catabolism of CYP27A1 18 0.56 8.46 3.44
45 INT155983 Gene_expression of Cyp11a1 7 0.58 2.6 3.38
46 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36
47 INT71195 Transcription of Cyp1a2 6 0.53 2.41 3.24
48 INT76024 Negative_regulation of Cyp3a11 7 0.53 2.96 3.16
49 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
50 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
51 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
52 INT145710 Localization of CYP2C9 9 0.75 1.66 2.89
53 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83
54 INT52084 Localization of Cyp2e1 6 0.71 1.99 2.79
55 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77
56 INT90960 Positive_regulation of Gene_expression of CYP2D6 9 0.50 2.06 2.76
57 INT207366 Negative_regulation of Gene_expression of CYP27A1 11 0.44 4.82 2.67
58 INT176205 Gene_expression of Cyp7a1 8 0.69 2.5 2.45
59 INT62653 Positive_regulation of CYP2C19 8 0.54 1.23 2.41
60 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
61 INT61225 Positive_regulation of Cyp27b1 8 0.31 2.32 2.24
62 INT143395 Regulation of CYP27A1 25 0.53 9.01 2.18
63 INT143686 Negative_regulation of Gene_expression of CYP2D6 4 0.58 0.83 2.16
64 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15
65 INT120234 Positive_regulation of Gene_expression of Cyp3a11 4 0.46 2.21 2.13
66 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
67 INT43416 Negative_regulation of Gene_expression of CYP4A11 2 0.02 0.55 2.08
68 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02
69 INT82441 Binding of Cyp4f18 4 0.23 1.07 1.99
70 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98
71 INT66237 Positive_regulation of Ptgis 5 0.33 1.49 1.96
72 INT101410 Negative_regulation of Positive_regulation of CYP2C9 5 0.42 0.23 1.96
73 INT66240 Localization of Ptgis 9 0.58 1.36 1.95
74 INT95797 Positive_regulation of CYP2C8 8 0.50 0.55 1.94
75 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92
76 INT29577 Negative_regulation of Cyp27b1 5 0.37 2.41 1.88
77 INT96723 Regulation of Cyp3a11 5 0.44 2 1.83
78 INT103024 Positive_regulation of Gene_expression of Ptgis 5 0.48 4.02 1.83
79 INT19831 Binding of Ptgis 3 0.08 3.33 1.77
80 INT15916 Positive_regulation of Ptgis 11 0.39 6.6 1.74
81 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
82 INT37838 Regulation of Cyp27b1 4 0.27 0.67 1.61
83 INT262117 Negative_regulation of Gene_expression of Cyp7a1 3 0.25 0.91 1.6
84 INT163861 Positive_regulation of Gene_expression of Cyp11a1 2 0.38 0.64 1.53
85 INT163858 Regulation of Gene_expression of Cyp11a1 1 0.46 0.55 1.53
86 INT87095 Positive_regulation of Gene_expression of CYP2C19 3 0.48 0 1.5
87 INT303913 Regulation of Regulation of CYP2D6 2 0.37 1.09 1.48
88 INT144738 Regulation of Gene_expression of CYP2D6 3 0.60 0 1.44
89 INT37441 Localization of Ptgis 7 0.10 5.02 1.43
90 INT180581 Negative_regulation of Protein_catabolism of CYP27A1 2 0.29 3.19 1.43
91 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
92 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
93 INT262123 Gene_expression of Cyp24a1 17 0.67 6.67 1.38
94 INT179695 Negative_regulation of CYP4F3 4 0.45 4.94 1.38
95 INT110551 Negative_regulation of Negative_regulation of CYP2D6 3 0.40 0.25 1.38
96 INT110550 Regulation of CYP2C8 3 0.45 1.59 1.34
97 INT83822 Protein_catabolism of CYP2C9 3 0.46 1.16 1.31
98 INT71281 Positive_regulation of Gene_expression of CYP2C9 13 0.62 5.11 1.3
99 INT115374 Positive_regulation of Gene_expression of Cyp2e1 6 0.67 4.36 1.27
100 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22
101 INT123284 Positive_regulation of Positive_regulation of Cyp2e1 3 0.46 2.34 1.22
102 INT5115 Negative_regulation of Gene_expression of Ptgis 9 0.33 3.33 1.2
103 INT331001 Positive_regulation of Localization of CYP2D6 1 0.48 0.23 1.18
104 INT331006 Positive_regulation of Localization of CYP2C9 1 0.34 0.13 1.17
105 INT94396 Regulation of Cyp1a2 4 0.60 0.37 1.15
106 INT72558 Regulation of CYP2C19 6 0.54 1.97 1.14
107 INT59679 Binding of Cyp2c6 3 0.48 0.2 1.14
108 INT134955 Positive_regulation of Transcription of Cyp1a2 2 0.38 0.52 1.14
109 INT134957 Positive_regulation of Transcription of Cyp3a11 1 0.42 0.43 1.11
110 INT134956 Transcription of Cyp3a11 1 0.48 0.43 1.1
111 INT24297 Regulation of CYP21A2 3 0.05 1.29 1.09
112 INT10033 Localization of PTGIS 10 0.69 6.8 1.07
113 INT165589 Positive_regulation of Cyp11a1 2 0.38 0.54 1.06
114 INT168395 Transcription of Cyp19a1 2 0.51 2.5 1.06
115 INT168397 Gene_expression of Cyp19a1 2 0.06 1.77 1.06
116 INT130996 Positive_regulation of Regulation of CYP2C9 1 0.34 0 1
117 INT67655 Regulation of Gene_expression of CYP4A11 2 0.28 0.77 0.99
118 INT132623 Transcription of Cyp2e1 2 0.53 0.56 0.98
119 INT217950 Positive_regulation of Negative_regulation of CYP21A2 2 0.03 1.34 0.97
120 INT79635 Localization of Cyp1a2 2 0.74 0.26 0.97
121 INT331007 Negative_regulation of Gene_expression of CYP21A2 1 0.02 1.34 0.97
122 INT168398 Localization of Cyp19a1 1 0.08 0.89 0.97
123 INT15917 Positive_regulation of Gene_expression of Ptgis 5 0.35 3.69 0.95
124 INT334977 Regulation of Gene_expression of Cyp7a1 2 0.40 0.43 0.94
125 INT56270 Negative_regulation of Binding of Cyp2e1 1 0.42 0.17 0.94
126 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
127 INT56271 Positive_regulation of Negative_regulation of Cyp2e1 1 0.46 0.17 0.93
128 INT179698 Positive_regulation of CYP4F3 5 0.54 3.86 0.91
129 INT71197 Positive_regulation of Gene_expression of Cyp27b1 3 0.20 0.49 0.89
130 INT95537 Transcription of CYP2D6 4 0.68 0.2 0.85
131 INT66236 Positive_regulation of Localization of Ptgis 4 0.33 0.13 0.84
132 INT71194 Transcription of Cyp27b1 4 0.15 0.99 0.84
133 INT179697 Regulation of CYP4F3 4 0.47 4.36 0.83
134 INT89599 Binding of TBXAS1 3 0.23 0.41 0.83
135 INT269764 Positive_regulation of Localization of CYP27A1 4 0.38 2.45 0.8
136 INT103023 Positive_regulation of Positive_regulation of Ptgis 1 0.18 0.7 0.8
137 INT78669 Negative_regulation of CYP2C18 2 0.33 1.45 0.79
138 INT139845 Negative_regulation of Cyp4f18 4 0.28 0.95 0.78
139 INT77927 Negative_regulation of Gene_expression of Cyp1a2 3 0.42 1.23 0.78
140 INT96725 Regulation of Gene_expression of Cyp3a11 2 0.30 0.3 0.77
141 INT142923 Binding of Cyp3a11 1 0.36 0.38 0.76
142 INT50501 Negative_regulation of TBXAS1 3 0.30 1.26 0.74
143 INT94550 Negative_regulation of Gene_expression of CYP2C19 2 0.38 0 0.74
144 INT144390 Positive_regulation of Negative_regulation of CYP2C9 4 0.49 2.03 0.72
145 INT47715 Negative_regulation of Cyp11a1 2 0.42 0.07 0.72
146 INT138040 Regulation of Gene_expression of CYP21A2 1 0.00 0.58 0.72
147 INT145711 Regulation of Positive_regulation of CYP2C9 1 0.45 0.64 0.71
148 INT197010 Positive_regulation of CYP7A1 4 0.47 1.75 0.7
149 INT229326 Negative_regulation of CYP7A1 3 0.29 1.03 0.7
150 INT133835 Regulation of Cyp2c6 1 0.45 0 0.69
151 INT71188 Binding of Cyp1a2 5 0.44 0.58 0.68
152 INT125635 Negative_regulation of Cyp2c6 3 0.59 0.18 0.66
153 INT127988 Gene_expression of TBXAS1 2 0.38 0.22 0.66
154 INT35705 Regulation of CYP27B1 1 0.23 0 0.66
155 INT163853 Negative_regulation of Gene_expression of Cyp11a1 1 0.32 0.17 0.64
156 INT133836 Regulation of Positive_regulation of Cyp2c6 1 0.27 0 0.64
157 INT174239 Gene_expression of CYP2C18 5 0.65 2.25 0.63
158 INT162444 Positive_regulation of CYP4A11 4 0.43 4.11 0.61
159 INT331002 Negative_regulation of Localization of CYP2D6 1 0.40 0.17 0.6
160 INT66239 Negative_regulation of Gene_expression of Ptgis 3 0.28 0.23 0.59
161 INT44016 Binding of Cyp27b1 3 0.10 0.53 0.59
162 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58
163 INT257885 Negative_regulation of Positive_regulation of CYP27A1 2 0.37 1.62 0.57
164 INT262093 Positive_regulation of Gene_expression of Cyp7a1 2 0.44 0.81 0.55
165 INT66238 Regulation of Gene_expression of Ptgis 3 0.23 0.13 0.54
166 INT142452 Regulation of Gene_expression of PTGIS 3 0.23 0.72 0.53
167 INT94397 Positive_regulation of Cyp4f18 2 0.04 0.44 0.53
168 INT296837 Negative_regulation of Gene_expression of PTGIS 2 0.17 1.11 0.52
169 INT163991 Positive_regulation of Regulation of Cyp2e1 1 0.70 0.28 0.52
170 INT142624 Regulation of Negative_regulation of CYP2D6 1 0.27 0 0.51
171 INT71187 Positive_regulation of Transcription of Cyp27b1 1 0.13 0.2 0.51
172 INT71196 Positive_regulation of Binding of Cyp27b1 1 0.13 0.19 0.51
173 INT163994 Positive_regulation of Binding of Cyp2e1 2 0.50 0.45 0.5
174 INT137556 Negative_regulation of Cyp19a1 3 0.35 1.53 0.48
175 INT71046 Localization of CYP19A1 2 0.78 1.38 0.48
176 INT330997 Regulation of Positive_regulation of CYP2C19 1 0.35 0.3 0.47
177 INT331000 Regulation of Positive_regulation of CYP2D6 1 0.43 0.3 0.47
178 INT135306 Binding of CYP2C8 10 0.46 4.37 0.46
179 INT19830 Positive_regulation of Binding of Ptgis 1 0.00 0.15 0.46
180 INT60540 Positive_regulation of CYP26A1 1 0.35 2.94 0.46
181 INT329888 Positive_regulation of Transcription of CYP7A1 1 0.20 0.9 0.46
182 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45
183 INT127890 Positive_regulation of Negative_regulation of CYP19A1 6 0.50 1.41 0.45
184 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
185 INT130669 Regulation of Gene_expression of CYP2C9 2 0.25 0.69 0.44
186 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
187 INT262087 Gene_expression of Cyp2d9 1 0.01 1.64 0.44
188 INT262095 Positive_regulation of Gene_expression of Cyp24a1 1 0.40 2.58 0.44
189 INT229307 Positive_regulation of Negative_regulation of CYP7A1 1 0.31 0.1 0.43
190 INT301564 Gene_expression of Cyp4f18 5 0.03 1.55 0.42
191 INT88678 Gene_expression of CYP27B1 8 0.75 2.11 0.41
192 INT179102 Binding of CYP4F3 4 0.29 1.75 0.41
193 INT218020 Positive_regulation of CYP27B1 3 0.49 0.15 0.41
194 INT156845 Negative_regulation of CYP24A1 2 0.41 2.04 0.41
195 INT173810 Positive_regulation of Gene_expression of CYP27A1 5 0.49 1.35 0.4
196 INT144386 Positive_regulation of Negative_regulation of CYP2D6 3 0.49 1.01 0.4
197 INT19832 Negative_regulation of Binding of Ptgis 1 0.00 0.16 0.4
198 INT176186 Negative_regulation of Cyp7a1 5 0.46 2.07 0.39
199 INT71190 Regulation of Gene_expression of Cyp27b1 1 0.13 0.17 0.39
200 INT71191 Regulation of Positive_regulation of Cyp27b1 1 0.13 0.17 0.39
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox