GO:0016717

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Name oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Categary Function
Go Slim No
Go Link GO:0016717
Unique Molecular Interactions 29
Total Molecular Interactions 41
Total Single Events 246
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. They are ordered first by their pain relevance and then by number of times they were reported for oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
2 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54
3 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
4 INT33976 Trmt2a Negative_regulation of Binding of Fads1 1 0.00 0 0.94
5 INT48455 Scd1 Regulation of Penk 1 0.06 0 0.88
6 INT70670 Scd1 Positive_regulation of Gene_expression of Penk 1 0.11 0.1 0.86
7 INT31707 Binding of Oprd1 and Fads1 1 0.01 0 0.44
8 INT43365 Scd1 Negative_regulation of Gnrh1 1 0.13 0.1 0.44
9 INT77924 Binding of SCD and Oprd1 1 0.00 0.25 0.4
10 INT77923 Negative_regulation of Binding of SCD and Oprd1 1 0.00 0.25 0.4
11 INT43366 Scd1 Regulation of Gene_expression of Gnrh1 1 0.08 0.07 0.39
12 INT43367 Scd1 Regulation of Gnrh1 1 0.08 0.07 0.39
13 INT43363 Scd1 Regulation of Barhl1 1 0.03 0.07 0.39
14 INT16811 Binding of Scd1 and Oprl1 1 0.00 0 0.24
15 INT26086 Binding of Scd1 and St8sia2 1 0.00 0.06 0.16
16 INT107476 SCD Positive_regulation of Gene_expression of Penk 1 0.00 0 0.16
17 INT335125 Me1 Positive_regulation of Localization of Fads2 1 0.07 0.09 0.16
18 INT107475 SCD Regulation of Gene_expression of Penk 1 0.00 0 0.1
19 INT36128 Binding of Scd1 and Mme 1 0.00 0 0.09
20 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05
21 INT342359 Arrd1 Positive_regulation of Scd1 1 0.01 0.8 0.04
22 INT194101 MKLN1 Positive_regulation of Binding of SCD 1 0.08 1.16 0
23 INT279901 Binding of FADS3 and USF1 1 0.35 4.71 0
24 INT194102 MKLN1 Regulation of Positive_regulation of SCD 1 0.07 1.13 0
25 INT279904 Binding of FADS3 and RS1 1 0.00 1.12 0
26 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0
27 INT279909 Binding of FADS3 and TGS1 1 0.12 6 0
28 INT152049 Scd1 Negative_regulation of Trav6-3 1 0.00 0.19 0
29 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. They are ordered first by their pain relevance and then by number of times they were reported in oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31705 Gene_expression of Fads1 12 0.22 1.43 6.69
2 INT3915 Gene_expression of SCD 25 0.57 13.94 6
3 INT12780 Binding of Fads1 7 0.08 0.07 5.34
4 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71
5 INT3854 Binding of SCD 16 0.41 11.14 3.7
6 INT116588 Transcription of Fads1 1 0.09 0 3.41
7 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26
8 INT49377 Negative_regulation of Scd1 11 0.49 9.84 1.88
9 INT116580 Regulation of Gene_expression of Fads1 1 0.03 0 1.85
10 INT121335 Localization of SCD 10 0.68 6.81 1.51
11 INT116581 Regulation of Transcription of Fads1 1 0.06 0 1.28
12 INT47802 Regulation of Binding of Fads1 1 0.06 0.07 0.92
13 INT65717 Regulation of Fads1 2 0.03 0.31 0.87
14 INT114504 Positive_regulation of Scd1 10 0.48 3.77 0.8
15 INT48454 Localization of Scd1 1 0.39 0 0.62
16 INT169274 Protein_catabolism of SCD 1 0.63 1.29 0.57
17 INT4597 Regulation of SCD 5 0.39 2.25 0.5
18 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47
19 INT158622 Positive_regulation of Fads1 1 0.02 0.21 0.45
20 INT43361 Binding of Scd1 1 0.10 0.08 0.42
21 INT43360 Negative_regulation of Scd1 1 0.13 0.09 0.4
22 INT4439 Positive_regulation of Scd1 1 0.34 0.19 0.39
23 INT155335 Negative_regulation of Positive_regulation of SCD 1 0.30 1.78 0.39
24 INT228685 Negative_regulation of Gene_expression of SCD 2 0.26 1.64 0.38
25 INT116585 Negative_regulation of Fads1 1 0.07 0 0.35
26 INT16808 Binding of Scd1 5 0.00 7.18 0.33
27 INT152338 Binding of FADS3 1 0.00 0 0.33
28 INT124019 Regulation of Scd1 1 0.01 0 0.31
29 INT345253 Negative_regulation of Gene_expression of Fads1 1 0.16 1.07 0.3
30 INT153732 Positive_regulation of Gene_expression of SCD 9 0.47 3.28 0.29
31 INT214503 Gene_expression of FADS3 3 0.75 7.81 0.18
32 INT335095 Localization of Fads2 1 0.31 0.09 0.16
33 INT170734 Positive_regulation of Gene_expression of Scd1 5 0.48 5.87 0.13
34 INT308736 Negative_regulation of Gene_expression of Fads2 1 0.02 0.19 0.07
35 INT327526 Negative_regulation of Negative_regulation of SCD 1 0.15 1.35 0.07
36 INT308730 Gene_expression of Fads2 1 0.04 0.19 0.06
37 INT170743 Negative_regulation of Gene_expression of Scd1 2 0.38 1.57 0
38 INT307203 Transcription of Scd1 2 0.32 1.11 0
39 INT273154 Positive_regulation of Localization of SCD 1 0.03 0.94 0
40 INT279925 Positive_regulation of FADS3 1 0.49 1.34 0
41 INT148405 Transcription of SCD 1 0.46 0.12 0
42 INT170740 Localization of Scd1 1 0.17 0.99 0
43 INT279943 Negative_regulation of Regulation of FADS3 1 0.41 0.91 0
44 INT279927 Negative_regulation of Gene_expression of FADS3 1 0.41 1.35 0
45 INT279926 Localization of FADS3 1 0.73 0.77 0
46 INT279933 Regulation of FADS3 1 0.60 0.9 0
47 INT138623 Negative_regulation of Gene_expression of Scd1 1 0.20 0.57 0
48 INT327560 Positive_regulation of Binding of SCD 1 0.29 1.07 0
49 INT279934 Regulation of Gene_expression of FADS3 1 0.60 1.77 0
50 INT307184 Positive_regulation of Transcription of Scd1 1 0.28 0 0
51 INT295103 Positive_regulation of Binding of Scd1 1 0.29 0.05 0
52 INT138630 Gene_expression of Scd1 1 0.37 0.56 0
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