GO:0016772

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Name transferase activity, transferring phosphorus-containing groups
Categary Function
Go Slim No
Go Link GO:0016772
Unique Molecular Interactions 2683
Total Molecular Interactions 3475
Total Single Events 24040
Pain Genes Associated 208

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transferase activity, transferring phosphorus-containing groups. They are ordered first by their pain relevance and then by number of times they were reported for transferase activity, transferring phosphorus-containing groups. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
3 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
4 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
5 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
6 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
7 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
8 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
9 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
10 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
11 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
12 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
13 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
14 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
15 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
16 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
17 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
18 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
19 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
20 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
21 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
22 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
23 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
24 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
25 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
26 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
27 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
28 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
29 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
30 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
31 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
32 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
33 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
34 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
35 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
36 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
37 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
38 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
39 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
40 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
41 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
42 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
43 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
44 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
45 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
46 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
47 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
48 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
49 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
50 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
51 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
52 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
53 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
54 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
55 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
56 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
57 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
58 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
59 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
60 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
61 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
62 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
63 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
64 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
65 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
66 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
67 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
68 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
69 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
70 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
71 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
72 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
73 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
74 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
75 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
76 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
77 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
78 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
79 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
80 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
81 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
82 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
83 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
84 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
85 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
86 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
87 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
88 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
89 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
90 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
91 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
92 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 0.04 1.35 1.4
93 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
94 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
95 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
96 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
97 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
98 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
99 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
100 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
101 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
102 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
103 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
104 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
105 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
106 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
107 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
108 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
109 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
110 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
111 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
112 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
113 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
114 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
115 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
116 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
117 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
118 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
119 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
120 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
121 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
122 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27
123 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27
124 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
125 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
126 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 0.02 0 1.26
127 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
128 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
129 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
130 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
131 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
132 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
133 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
134 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23
135 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
136 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
137 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
138 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
139 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
140 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
141 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
142 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
143 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
144 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
145 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
146 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
147 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
148 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
149 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
150 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
151 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
152 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
153 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
154 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
155 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
156 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
157 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
158 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
159 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
160 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
161 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
162 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
163 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
164 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
165 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
166 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
167 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
168 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
169 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
170 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
171 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
172 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
173 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
174 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
175 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
176 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
177 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12
178 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
179 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
180 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
181 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
182 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
183 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
184 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
185 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
186 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
187 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
188 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09
189 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
190 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
191 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
192 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
193 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
194 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
195 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
196 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
197 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
198 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
199 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
200 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for transferase activity, transferring phosphorus-containing groups. They are ordered first by their pain relevance and then by number of times they were reported in transferase activity, transferring phosphorus-containing groups. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
2 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
3 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
4 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
5 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
6 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
7 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
8 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
9 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
10 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
11 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
12 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
13 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
14 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
15 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
16 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
17 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
18 INT4153 Binding of Insrr 109 0.40 17.99 72.15
19 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
20 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
21 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
22 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
23 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
24 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
25 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
26 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
27 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
28 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
29 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
30 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
31 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
32 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
33 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
34 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
35 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
36 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
37 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
38 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
39 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
40 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
41 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
42 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
43 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
44 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
45 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
46 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
47 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
48 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
49 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
50 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
51 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
52 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
53 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
54 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
55 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
56 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
57 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
58 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
59 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
60 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
61 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
62 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39
63 INT117527 Binding of Prkca 25 0.48 6.43 21.05
64 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
65 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
66 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
67 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
68 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57
69 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
70 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84
71 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
72 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
73 INT6461 Gene_expression of Npr1 35 0.75 10.38 17.58
74 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
75 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
76 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
77 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72
78 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
79 INT79458 Localization of Prkca 30 0.81 11.13 15.78
80 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
81 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
82 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
83 INT38253 Localization of Trib3 35 0.63 10.28 15.42
84 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
85 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93
86 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
87 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
88 INT8989 Binding of Npr1 25 0.36 5.52 14.58
89 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
90 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
91 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
92 INT84496 Regulation of Positive_regulation of Ephb1 18 0.61 10.16 13.92
93 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
94 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
95 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
96 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
97 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
98 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
99 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
100 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
101 INT100821 Localization of Ros1 59 0.60 45.26 11.92
102 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
103 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
104 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
105 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
106 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9
107 INT118678 Phosphorylation of Camk4 22 0.82 9.4 10.7
108 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
109 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
110 INT790 Gene_expression of Mastl 22 0.68 4.56 10.23
111 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14
112 INT50615 Positive_regulation of Positive_regulation of Insrr 11 0.19 5.5 10.05
113 INT13606 Negative_regulation of Negative_regulation of Npr1 13 0.40 1.21 10.01
114 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10
115 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
116 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
117 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
118 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
119 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
120 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
121 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
122 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
123 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2
124 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
125 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17
126 INT123040 Phosphorylation of Grk4 12 0.60 0.31 9.14
127 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
128 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05
129 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
130 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
131 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
132 INT20999 Negative_regulation of Binding of Insrr 17 0.47 3.53 8.93
133 INT141185 Regulation of Ros1 30 0.24 20.73 8.88
134 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88
135 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
136 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78
137 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
138 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
139 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
140 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
141 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
142 INT12859 Localization of Insrr 16 0.32 2.68 8.07
143 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
144 INT127853 Localization of Ephb1 20 0.74 5.47 7.96
145 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
146 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
147 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49
148 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
149 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
150 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
151 INT13348 Negative_regulation of Mastl 11 0.36 3.33 7.28
152 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
153 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
154 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
155 INT157430 Gene_expression of Ephb6 18 0.70 8.13 7.14
156 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
157 INT92734 Binding of Ephb1 5 0.37 3.86 7.02
158 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99
159 INT110104 Localization of Prkce 17 0.79 3.75 6.92
160 INT62260 Negative_regulation of Gene_expression of Insrr 10 0.06 1.36 6.92
161 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79
162 INT73709 Binding of Mastl 11 0.40 3.39 6.76
163 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
164 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
165 INT48922 Regulation of Gene_expression of Ephb1 14 0.50 5.73 6.47
166 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44
167 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
168 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
169 INT7021 Positive_regulation of Negative_regulation of Npr1 8 0.22 1.02 6.36
170 INT115849 Localization of Prkcc 5 0.77 0.65 6.26
171 INT116641 Phosphorylation of Gsk3a 12 0.71 4.3 6.22
172 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
173 INT143357 Binding of Ros1 48 0.36 27.76 6
174 INT1493 Positive_regulation of Prkacb 8 0.59 2.75 5.99
175 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96
176 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
177 INT6195 Transcription of Npr1 9 0.69 3 5.94
178 INT121870 Positive_regulation of Gene_expression of Camk4 24 0.70 15.63 5.83
179 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
180 INT181053 Regulation of Ephb1 6 0.45 6.17 5.77
181 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72
182 INT113700 Positive_regulation of Chuk 30 0.41 21.17 5.69
183 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66
184 INT7018 Positive_regulation of Gene_expression of Npr1 10 0.59 5.09 5.66
185 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
186 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
187 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57
188 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
189 INT50704 Binding of Trib3 13 0.31 6.33 5.46
190 INT65914 Gene_expression of Gnptab 7 0.04 1.13 5.44
191 INT13706 Localization of Npr1 10 0.59 0.83 5.42
192 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
193 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
194 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
195 INT118673 Regulation of Camk4 12 0.48 7.92 5.22
196 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
197 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
198 INT126847 Binding of Ephb1 15 0.46 6.47 5.17
199 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
200 INT96258 Positive_regulation of Pik3cd 14 0.43 8.74 5.16
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