GO:0016798

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Name hydrolase activity, acting on glycosyl bonds
Categary Function
Go Slim Yes
Go Link GO:0016798
Unique Molecular Interactions 155
Total Molecular Interactions 184
Total Single Events 2330
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on glycosyl bonds. They are ordered first by their pain relevance and then by number of times they were reported for hydrolase activity, acting on glycosyl bonds. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
2 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
3 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51
4 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
5 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
6 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
7 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
8 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35
9 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35
10 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
11 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
12 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27
13 INT60794 Binding of TREH and Chrna9 1 0.00 0 1.04
14 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
15 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
16 INT77120 Pomc Regulation of HYAL1 1 0.01 0 0.61
17 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54
18 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54
19 INT60793 Negative_regulation of Binding of TREH and Chrna9 1 0.00 0 0.53
20 INT60788 Binding of TREH and BHLHE23 1 0.00 0 0.52
21 INT43646 Negative_regulation of Binding of Pomc and Lct 1 0.38 0 0.47
22 INT72203 GH1 Regulation of OGG1 1 0.10 0 0.46
23 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
24 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45
25 INT8356 Binding of YY1 and Smpd1 1 0.32 0 0.43
26 INT243682 IRF6 Positive_regulation of NEU2 1 0.01 0.18 0.43
27 INT61131 NEU2 Positive_regulation of CPQ 1 0.01 0 0.41
28 INT354062 Avp Regulation of Lyz2 1 0.00 0.12 0.38
29 INT129769 Binding of LYZ and S100B 1 0.33 0.86 0.37
30 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
31 INT87769 Binding of Acot1 and Treh 1 0.00 0 0.35
32 INT210263 Mtx1 Regulation of Gene_expression of LYZ 1 0.00 0.33 0.32
33 INT210935 Il6 Positive_regulation of Smpd1 1 0.02 0.46 0.3
34 INT223965 Binding of AMY2A and Bglap 1 0.05 1.5 0.28
35 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
36 INT35179 Binding of STT3A and LYZ 1 0.07 0.38 0.25
37 INT327383 Il13 Positive_regulation of Gene_expression of Cd38 1 0.19 0 0.25
38 INT149940 Smpd1 Positive_regulation of spc 1 0.03 0.19 0.24
39 INT195544 Lct Positive_regulation of Transcription of Grm2 1 0.01 0.06 0.24
40 INT287101 Binding of Bdnf and Mutyh 1 0.04 0.58 0.24
41 INT195547 Lct Positive_regulation of Transcription of Grm3 1 0.00 0.06 0.24
42 INT184192 IL1B Positive_regulation of SPAM1 1 0.04 0.49 0.24
43 INT195553 Lct Positive_regulation of Grm2 1 0.02 0.05 0.23
44 INT41787 IFNA2 Negative_regulation of Glb1 1 0.04 0.09 0.23
45 INT184191 IL1B Positive_regulation of Gene_expression of SPAM1 1 0.03 0.59 0.23
46 INT195548 Lct Positive_regulation of Grm3 1 0.00 0.06 0.23
47 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
48 INT319555 gr Positive_regulation of Positive_regulation of Hpse 1 0.09 0.11 0.22
49 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19
50 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18
51 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18
52 INT184194 Binding of HRAS and SPAM1 1 0.00 0.26 0.17
53 INT245641 Nr3c2 Regulation of Gene_expression of Hpse 1 0.14 2.67 0.17
54 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17
55 INT245314 Binding of HYAL1 and MMP2 1 0.16 0.29 0.15
56 INT245312 Negative_regulation of Binding of HYAL1 and MMP2 1 0.19 0.29 0.15
57 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15
58 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13
59 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13
60 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13
61 INT311191 ecs Negative_regulation of HPSE 1 0.00 0.94 0.12
62 INT134615 Binding of Neu3 and Trpv1 1 0.01 0.06 0.11
63 INT190631 Gusb Positive_regulation of Tlr4 1 0.08 0.44 0.11
64 INT341879 Oxt Negative_regulation of Positive_regulation of Hpse 1 0.01 0.83 0.11
65 INT214957 Vamp2 Regulation of Neu3 1 0.00 0 0.1
66 INT214954 Vamp1 Regulation of Neu3 1 0.00 0 0.1
67 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1
68 INT204904 Tlr4 Positive_regulation of Hexb 1 0.14 0.09 0.09
69 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09
70 INT188964 Binding of AMBP and NAGLU 1 0.01 1.27 0.09
71 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09
72 INT204884 Tlr4 Negative_regulation of Negative_regulation of Hexb 1 0.13 0.09 0.09
73 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
74 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08
75 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
76 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08
77 INT249198 CD38 Positive_regulation of CA2 1 0.16 0.16 0.08
78 INT195549 Lct Positive_regulation of Rela 1 0.01 0 0.07
79 INT271493 Ctbs Negative_regulation of Hand1 1 0.04 0.63 0.07
80 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
81 INT159463 Ptprn2 Negative_regulation of HPSE 1 0.00 0 0.07
82 INT211875 Binding of CDS1 and SMUG1 1 0.03 1.04 0.07
83 INT40240 CPOX Negative_regulation of Localization of LYZ 1 0.22 0.16 0.07
84 INT147112 LYZ Regulation of Binding of LTF 1 0.14 1.02 0.07
85 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07
86 INT330487 Binding of MME and HPSE 1 0.35 0 0.06
87 INT195551 Lct Regulation of Gene_expression of Grm2 1 0.01 0 0.05
88 INT178968 Slc7a2 Negative_regulation of Glb1 1 0.02 1.77 0.05
89 INT195221 Binding of CSRP1 and NAGLU 1 0.17 0.25 0.05
90 INT80067 Penk Positive_regulation of Gene_expression of Glb1 1 0.07 0.1 0.05
91 INT214033 OGG1 Negative_regulation of BPIFA4P 1 0.08 0.71 0.05
92 INT14440 Binding of GLB1 and NEU1 1 0.00 0.09 0.05
93 INT204906 Tlr4 Negative_regulation of Hexb 1 0.13 0.09 0.04
94 INT302982 Smpd1 Positive_regulation of Gene_expression of Smpd3 1 0.30 0.64 0.04
95 INT249158 CD38 Regulation of CA2 1 0.13 0.07 0.04
96 INT280616 Binding of Neu2 and Mpl 1 0.00 0.12 0.04
97 INT270330 Binding of HYAL1 and TIMP1 1 0.00 0.2 0.04
98 INT246786 Ogg1 Regulation of Phosphorylation of Tsc2 1 0.20 0.42 0.04
99 INT154339 Binding of IGLL1 and MAN1A1 1 0.00 0 0.03
100 INT246791 Tsc2 Regulation of Ogg1 1 0.27 0.56 0.03
101 INT314401 Binding of Ctbs and Gpsm2 1 0.10 0 0
102 INT327465 Binding of Cd4 and Neu1 1 0.06 0.73 0
103 INT191097 Neu1 Positive_regulation of Shc1 1 0.04 1.96 0
104 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0
105 INT306511 Binding of XRCC6 and Ung 1 0.00 0.78 0
106 INT246799 Pik3c3 Positive_regulation of Negative_regulation of Ogg1 1 0.04 0 0
107 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0
108 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
109 INT246796 Ros1 Positive_regulation of Negative_regulation of Ogg1 1 0.04 0 0
110 INT245589 Binding of Glb1 and B3galt6 1 0.01 0.94 0
111 INT300664 Binding of Gla and Thra 1 0.08 0 0
112 INT182403 Binding of OGG1 and XRCC1 1 0.35 0.14 0
113 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0
114 INT185733 Hpse Positive_regulation of Gene_expression of Tnfrsf11b 1 0.20 0.24 0
115 INT240722 Cd38 Positive_regulation of Localization of Ca2 1 0.04 0.79 0
116 INT303822 Tdp1 Regulation of TREH 1 0.02 0.92 0
117 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0
118 INT291108 AGL Regulation of Gene_expression of PDK4 1 0.01 0 0
119 INT321126 Negative_regulation of Binding of F5 and Lyz2 1 0.00 0.32 0
120 INT283859 Binding of ACTN4 and TREH 1 0.00 1.61 0
121 INT246812 Ros1 Positive_regulation of Ogg1 1 0.05 0 0
122 INT321128 Binding of F5 and Lyz2 1 0.00 0.32 0
123 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0
124 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0
125 INT314398 Ptpn6 Regulation of Gene_expression of Ctbs 1 0.03 0 0
126 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0
127 INT264864 Cd38 Positive_regulation of Localization of INS 1 0.06 0.51 0
128 INT322875 Binding of OSM and Lyz2 1 0.00 0 0
129 INT182407 Binding of NFYA and OGG1 1 0.02 0.07 0
130 INT70122 NAGLU Positive_regulation of Localization of Anpep 1 0.10 0 0
131 INT257341 Binding of Neu2 and Cyba 1 0.00 0.29 0
132 INT328422 Protein_catabolism of Neu1 Positive_regulation of Dnase2b 1 0.01 0.67 0
133 INT184196 GOPC Negative_regulation of HYAL1 1 0.02 0 0
134 INT246795 Ros1 Positive_regulation of Phosphorylation of Ogg1 1 0.05 0 0
135 INT162510 Binding of ITPR1 and HPSE 1 0.02 0.05 0
136 INT246810 Negative_regulation of Akt1 Positive_regulation of Ogg1 1 0.42 0 0
137 INT317597 Binding of Gnrh1 and Hpse 1 0.08 0 0
138 INT349105 Hyal1 Positive_regulation of Gene_expression of Il6 1 0.30 0.25 0
139 INT191837 Binding of SMUG1 and Airn 1 0.02 0.98 0
140 INT103769 AMY2A Positive_regulation of IFNA2 1 0.01 0.26 0
141 INT333637 Smpd1 Positive_regulation of IRF3 1 0.09 0.62 0
142 INT184195 IL1B Regulation of Gene_expression of SPAM1 1 0.02 0 0
143 INT222537 Binding of Nmu and Hpse 1 0.01 0.15 0
144 INT323185 Binding of LIG4 and OGG1 1 0.02 0.32 0
145 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0
146 INT254044 Binding of BGLAP and NEU4 1 0.04 0.29 0
147 INT314679 NEU1 Negative_regulation of TP53 1 0.12 1.23 0
148 INT246800 Binding of Tsc2 and Ogg1 1 0.16 0.38 0
149 INT322874 Binding of PDCD10 and Lyz2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on glycosyl bonds. They are ordered first by their pain relevance and then by number of times they were reported in hydrolase activity, acting on glycosyl bonds. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
2 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
3 INT10585 Localization of NAGLU 53 0.80 23.32 12.75
4 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
5 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98
6 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7
7 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16
8 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7
9 INT20389 Localization of LYZ 19 0.79 4.58 6.25
10 INT9779 Gene_expression of Glb1 23 0.58 8.01 6.04
11 INT163540 Gene_expression of HYAL1 27 0.68 12.11 5.95
12 INT3731 Negative_regulation of Neu1 17 0.39 8.35 5.67
13 INT76313 Gene_expression of CD38 30 0.64 20.74 5.27
14 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17
15 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16
16 INT171033 Localization of SMPD1 15 0.16 11.92 5.16
17 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08
18 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98
19 INT78524 Positive_regulation of Neu1 6 0.67 8.9 4.4
20 INT1701 Localization of Neu1 11 0.69 6.36 4.18
21 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
22 INT68978 Regulation of Positive_regulation of Hpse 6 0.45 1.88 4.02
23 INT84430 Negative_regulation of Smpd1 22 0.59 10.33 3.95
24 INT14619 Positive_regulation of Localization of NAGLU 18 0.62 7.73 3.94
25 INT26891 Gene_expression of OGG1 21 0.74 2.08 3.64
26 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63
27 INT49006 Gene_expression of Neu3 13 0.08 1.22 3.63
28 INT127006 Phosphorylation of Neu3 3 0.02 0.43 3.61
29 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
30 INT13321 Negative_regulation of Hpse 11 0.56 4.64 3.39
31 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87
32 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85
33 INT78568 Negative_regulation of Gene_expression of Glb1 4 0.30 0.78 2.84
34 INT2464 Gene_expression of AMY2A 21 0.75 13.76 2.78
35 INT171013 Regulation of SMPD1 4 0.11 4.84 2.74
36 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73
37 INT24895 Positive_regulation of LYZ 25 0.70 17.92 2.64
38 INT118887 Positive_regulation of Neu3 3 0.01 8.39 2.62
39 INT39266 Negative_regulation of Localization of Neu1 6 0.30 4.66 2.6
40 INT13414 Regulation of Regulation of Hpse 4 0.16 1.71 2.55
41 INT137616 Gene_expression of Cd38 19 0.67 9.37 2.54
42 INT171032 Positive_regulation of SMPD1 9 0.12 8.94 2.52
43 INT175797 Regulation of Gene_expression of Hpse 6 0.07 6.52 2.49
44 INT3735 Localization of Neu1 9 0.73 3.83 2.46
45 INT27217 Negative_regulation of LYZ 6 0.42 3.1 2.26
46 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03
47 INT38008 Positive_regulation of Gene_expression of NAGLU 6 0.44 6.64 2
48 INT119018 Gene_expression of TREH 22 0.65 12.44 1.95
49 INT117934 Gene_expression of Cd38 11 0.68 6.5 1.95
50 INT20388 Binding of LYZ 8 0.39 5.65 1.93
51 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87
52 INT2606 Localization of NEU1 10 0.41 4.6 1.82
53 INT104672 Negative_regulation of Neu3 4 0.14 4.67 1.82
54 INT4028 Regulation of HYAL1 8 0.54 1.55 1.8
55 INT48253 Positive_regulation of AMY2A 8 0.59 3.86 1.79
56 INT86914 Positive_regulation of Smpd1 11 0.43 4.73 1.74
57 INT74707 Negative_regulation of Hpse 4 0.58 2.29 1.73
58 INT114409 Gene_expression of Lyz2 2 0.35 0 1.65
59 INT151743 Binding of Gusb 11 0.24 8.73 1.63
60 INT58931 Binding of NAGLU 11 0.34 4.47 1.63
61 INT33591 Negative_regulation of Positive_regulation of Hpse 6 0.32 3.42 1.63
62 INT129492 Gene_expression of Hpse 11 0.75 6.56 1.59
63 INT74955 Negative_regulation of HPSE 6 0.57 4.75 1.57
64 INT168860 Positive_regulation of Cd38 5 0.70 4.07 1.57
65 INT46643 Negative_regulation of HYAL1 7 0.37 4.65 1.55
66 INT39997 Negative_regulation of Gla 8 0.59 6.38 1.51
67 INT122449 Localization of SMUG1 10 0.67 7.97 1.47
68 INT168861 Positive_regulation of Gene_expression of Cd38 2 0.50 2.01 1.47
69 INT184529 Negative_regulation of SMUG1 8 0.49 7.06 1.46
70 INT184532 Binding of SMUG1 7 0.21 5.73 1.45
71 INT20233 Negative_regulation of SMPD1 8 0.51 4.19 1.4
72 INT4029 Positive_regulation of HYAL1 10 0.69 2 1.39
73 INT28787 Negative_regulation of Localization of LYZ 4 0.35 0.88 1.39
74 INT67133 Gene_expression of Gusb 14 0.75 18.57 1.37
75 INT65553 Regulation of Hpse 6 0.27 3.89 1.37
76 INT66274 Gene_expression of Ctbs 9 0.39 1.16 1.35
77 INT181856 Gene_expression of SPAM1 2 0.22 4.5 1.35
78 INT168859 Regulation of Cd38 1 0.27 0.11 1.33
79 INT1957 Localization of AMY2A 6 0.68 2.85 1.31
80 INT41805 Localization of Neu3 4 0.10 0.33 1.28
81 INT148638 Protein_catabolism of Hpse 1 0.48 1.09 1.28
82 INT26890 Negative_regulation of Gene_expression of OGG1 2 0.34 0.13 1.26
83 INT291800 Positive_regulation of NEU2 2 0.01 0.57 1.26
84 INT28788 Regulation of LYZ 5 0.42 1.8 1.24
85 INT325005 Positive_regulation of Gene_expression of SMUG1 3 0.25 0.93 1.23
86 INT117933 Positive_regulation of Gene_expression of Cd38 3 0.38 1.62 1.23
87 INT47010 Negative_regulation of Gusb 6 0.43 4.16 1.2
88 INT168864 Positive_regulation of Positive_regulation of Cd38 1 0.47 0.05 1.18
89 INT86319 Protein_catabolism of HYAL1 5 0.64 1.09 1.17
90 INT28790 Regulation of Localization of LYZ 4 0.50 0.74 1.16
91 INT31326 Binding of TREH 7 0.17 2.29 1.14
92 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12
93 INT62377 Regulation of Neu2 2 0.01 0.51 1.11
94 INT57209 Regulation of Gene_expression of Glb1 3 0.23 0.99 1.09
95 INT175794 Negative_regulation of Gene_expression of Hpse 2 0.12 1.82 1.08
96 INT223960 Positive_regulation of Transcription of AMY2A 1 0.08 4.88 1.07
97 INT223961 Transcription of AMY2A 1 0.11 4.83 1.06
98 INT127003 Binding of Neu3 7 0.02 1.57 1.05
99 INT96229 Localization of HPSE 3 0.20 2.76 1.05
100 INT185501 Localization of NEU2 4 0.02 1.08 1.04
101 INT193069 Positive_regulation of Gene_expression of CD38 4 0.15 4.06 1.01
102 INT165835 Positive_regulation of Lct 3 0.49 1.03 0.99
103 INT78569 Positive_regulation of Gene_expression of Glb1 2 0.38 0.24 0.99
104 INT171038 Positive_regulation of Localization of SMPD1 2 0.08 1.8 0.99
105 INT493 Binding of Treh 5 0.02 0.32 0.97
106 INT127005 Positive_regulation of Localization of Neu3 1 0.02 0.33 0.97
107 INT59492 Transcription of HYAL1 2 0.11 0.92 0.96
108 INT55580 Localization of Hpse 5 0.23 3.51 0.89
109 INT2607 Negative_regulation of Localization of NEU1 3 0.30 1.52 0.88
110 INT20390 Negative_regulation of Binding of LYZ 2 0.28 0.24 0.87
111 INT112760 Negative_regulation of Positive_regulation of Smpd1 2 0.38 1.45 0.84
112 INT193019 Positive_regulation of Positive_regulation of SMUG1 6 0.39 4.7 0.83
113 INT37747 Localization of Gusb 4 0.69 1.91 0.82
114 INT171030 Positive_regulation of Gene_expression of SMPD1 2 0.09 0.92 0.82
115 INT109854 Negative_regulation of Positive_regulation of Hpse 1 0.23 0 0.81
116 INT65552 Binding of Hpse 2 0.30 2.48 0.8
117 INT181858 Binding of HYAL1 8 0.16 2.22 0.79
118 INT110240 Positive_regulation of Lyz2 1 0.00 0.96 0.79
119 INT110241 Negative_regulation of Positive_regulation of Lyz2 1 0.00 0.97 0.79
120 INT131384 Binding of Mutyh 5 0.26 2.41 0.78
121 INT3732 Negative_regulation of Localization of Neu1 3 0.01 1 0.75
122 INT702 Negative_regulation of TREH 3 0.36 1.01 0.75
123 INT58866 Regulation of Neu1 3 0.08 1.13 0.75
124 INT93618 Positive_regulation of TREH 6 0.16 2.31 0.73
125 INT181867 Positive_regulation of Positive_regulation of Neu1 1 0.49 0.93 0.72
126 INT171024 Negative_regulation of Localization of SMPD1 1 0.07 1.29 0.72
127 INT72654 Regulation of Localization of Neu1 1 0.02 0.34 0.72
128 INT118886 Regulation of Positive_regulation of Neu3 1 0.01 0.61 0.72
129 INT20316 Regulation of Neu1 1 0.05 0.19 0.7
130 INT39999 Gene_expression of Gla 7 0.59 3.27 0.69
131 INT43644 Binding of Lct 1 0.38 0 0.69
132 INT164589 Negative_regulation of Positive_regulation of Glb1 1 0.43 1.16 0.67
133 INT33662 Regulation of Lyz2 1 0.04 0.08 0.66
134 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65
135 INT76902 Binding of AGL 3 0.02 2.23 0.64
136 INT164590 Positive_regulation of Glb1 2 0.69 1.77 0.64
137 INT96339 Protein_catabolism of HPSE 5 0.96 2.87 0.63
138 INT166920 Binding of Neu1 2 0.21 2.67 0.63
139 INT5261 Localization of AGL 10 0.36 3.17 0.61
140 INT317596 Positive_regulation of Gene_expression of Hpse 3 0.14 2.24 0.6
141 INT182435 Localization of OGG1 36 0.76 1.66 0.58
142 INT28876 Positive_regulation of Localization of LYZ 3 0.68 0.46 0.58
143 INT45208 Regulation of NEU1 2 0.10 3.79 0.58
144 INT96016 Negative_regulation of Lct 2 0.41 0.69 0.58
145 INT129493 Protein_catabolism of Hpse 2 0.55 2.81 0.57
146 INT71414 Binding of Neu2 1 0.02 0 0.57
147 INT23118 Positive_regulation of Gene_expression of AGL 4 0.30 1.74 0.54
148 INT171043 Negative_regulation of Gene_expression of SMPD1 2 0.08 1.15 0.53
149 INT204863 Gene_expression of Hexb 3 0.44 2.57 0.52
150 INT62184 Binding of AMY2A 3 0.41 1.06 0.52
151 INT177436 Binding of HPSE 2 0.47 1.81 0.52
152 INT215854 Positive_regulation of Gene_expression of Hexb 1 0.34 2.42 0.52
153 INT214945 Regulation of Neu3 11 0.01 1.65 0.51
154 INT67848 Localization of Neu2 5 0.07 1.17 0.51
155 INT14450 Binding of NEU1 7 0.14 5.1 0.5
156 INT165836 Positive_regulation of Positive_regulation of Lct 2 0.49 0.52 0.5
157 INT59493 Regulation of Transcription of HYAL1 1 0.00 0 0.5
158 INT165837 Negative_regulation of Positive_regulation of Lct 1 0.41 0.51 0.49
159 INT190590 Localization of Hpse 2 0.28 0.49 0.48
160 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47
161 INT102631 Localization of HYAL1 4 0.26 1.79 0.46
162 INT2610 Positive_regulation of Localization of NEU1 2 0.12 0.7 0.44
163 INT117932 Positive_regulation of Cd38 2 0.35 1.17 0.43
164 INT3689 Gene_expression of Lct 2 0.19 0.78 0.43
165 INT48326 Negative_regulation of Localization of Gusb 1 0.23 0.65 0.43
166 INT47915 Negative_regulation of NAGLU 2 0.22 0.66 0.42
167 INT134731 Localization of Cd38 4 0.70 0.87 0.41
168 INT177437 Transcription of HPSE 2 0.23 3.44 0.41
169 INT84900 Positive_regulation of Localization of Hpse 1 0.16 0.16 0.41
170 INT43645 Negative_regulation of Binding of Lct 1 0.33 0 0.41
171 INT235063 Positive_regulation of Gene_expression of Gla 2 0.04 0.81 0.39
172 INT184203 Regulation of SPAM1 2 0.17 1.43 0.39
173 INT184197 Localization of SPAM1 1 0.21 1.49 0.39
174 INT319548 Positive_regulation of Localization of Hpse 1 0.17 0.08 0.38
175 INT129302 Positive_regulation of Gene_expression of TREH 4 0.49 1.28 0.37
176 INT9778 Regulation of Glb1 4 0.19 1.48 0.37
177 INT342278 Localization of Lyz2 2 0.03 0.37 0.37
178 INT30370 Negative_regulation of AMY2A 7 0.49 3.36 0.36
179 INT47175 Negative_regulation of Negative_regulation of AGL 4 0.24 1.19 0.36
180 INT22236 Negative_regulation of CD38 2 0.41 0.1 0.36
181 INT129494 Regulation of Gene_expression of Hpse 2 0.23 1.36 0.36
182 INT129495 Negative_regulation of Gene_expression of Hpse 1 0.36 0.52 0.36
183 INT350224 Regulation of NEU2 1 0.00 0.25 0.35
184 INT15031 Positive_regulation of Treh 1 0.03 0 0.35
185 INT74954 Positive_regulation of Positive_regulation of HPSE 2 0.40 0.45 0.34
186 INT79189 Transcription of Glb1 1 0.29 0 0.34
187 INT55784 Negative_regulation of Neu1 4 0.24 1.93 0.33
188 INT32138 Positive_regulation of Neu2 3 0.02 0.86 0.33
189 INT55582 Positive_regulation of Negative_regulation of Hpse 2 0.13 0.56 0.32
190 INT177439 Negative_regulation of Positive_regulation of HPSE 1 0.21 1.48 0.32
191 INT65389 Negative_regulation of Treh 1 0.02 0.15 0.32
192 INT184205 Binding of SPAM1 3 0.09 0.86 0.31
193 INT350226 Negative_regulation of Positive_regulation of NEU2 1 0.00 0.14 0.31
194 INT173329 Protein_catabolism of SMPD1 1 0.13 0 0.31
195 INT264860 Binding of Cd38 1 0.39 2.36 0.31
196 INT214579 Positive_regulation of CD38 4 0.24 1.22 0.3
197 INT181855 Negative_regulation of Gene_expression of HYAL1 1 0.10 0.59 0.3
198 INT318060 Phosphorylation of SMUG1 4 0.69 2.39 0.29
199 INT181854 Positive_regulation of Gene_expression of HYAL1 2 0.14 0.58 0.29
200 INT83288 Negative_regulation of NEU4 12 0.51 3.58 0.28
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