GO:0016805

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Name dipeptidase activity
Categary Function
Go Slim No
Go Link GO:0016805
Unique Molecular Interactions 32
Total Molecular Interactions 44
Total Single Events 422
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dipeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported for dipeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT255317 Binding of Dpep1 and Nav1 1 0.01 0 2.42
2 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27
3 INT255318 Binding of Dpep1 and Nrcam 1 0.00 0 2.16
4 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 0.03 0 1.52
5 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
6 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
7 INT255324 Negative_regulation of Binding of Dpep1 and 2E 1 0.02 0 0.73
8 INT255325 Binding of Dpep1 and 2E 1 0.02 0 0.73
9 INT255319 Binding of Dpep1 and Kcnq2 1 0.01 0 0.6
10 INT255320 Binding of Dpep1 and Kcnq3 1 0.01 0 0.6
11 INT255326 Binding of Dpep1 and AIS 1 0.00 0 0.6
12 INT130469 Tubgcp2 Negative_regulation of Naalad2 1 0.05 0.44 0.5
13 INT323905 Positive_regulation of CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
14 INT323904 CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
15 INT323903 CNDP1 Positive_regulation of IL10 1 0.00 0.9 0.46
16 INT255322 Binding of Dpep1 and Csnk2b 1 0.01 0 0.29
17 INT255316 Csnk2b Regulation of Binding of Dpep1 1 0.01 0 0.22
18 INT167523 Binding of Pepd and Aaas 1 0.02 0.5 0.15
19 INT106034 PEPD Positive_regulation of Protein_catabolism of COL7A1 1 0.42 0.33 0.12
20 INT332269 Cndp2 Negative_regulation of Tenc1 1 0.41 0.8 0.05
21 INT340086 Binding of Tgfb1 and Cndp2 1 0.04 0.38 0
22 INT164188 SLPI Negative_regulation of Localization of CNDP2 1 0.03 0 0
23 INT332268 Binding of Cndp2 and Tenc1 1 0.05 0.17 0
24 INT164181 NLRP2 Negative_regulation of Localization of CNDP2 1 0.05 0 0
25 INT223428 Binding of Cndp2 and Rnpep 1 0.02 0 0
26 INT164184 NLRP2 Negative_regulation of CNDP2 1 0.05 0 0
27 INT284094 VWF Negative_regulation of CNDP2 1 0.14 1.16 0
28 INT164187 SLPI Negative_regulation of CNDP2 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for dipeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported in dipeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1728 Negative_regulation of Cndp2 36 0.57 3.76 25.39
2 INT119777 Negative_regulation of Naalad2 9 0.40 5.93 10.11
3 INT16687 Regulation of Cndp2 6 0.44 0.23 6.11
4 INT141558 Positive_regulation of Naalad2 2 0.45 2.41 6.04
5 INT16688 Positive_regulation of Cndp2 11 0.49 1.12 5.86
6 INT23551 Negative_regulation of CNDP2 13 0.38 3.05 5.05
7 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06
8 INT93339 Gene_expression of Naalad2 4 0.10 1.73 4.03
9 INT14625 Binding of Dpep1 2 0.02 0 3.36
10 INT1727 Gene_expression of Cndp2 22 0.74 4.28 3.34
11 INT45199 Protein_catabolism of Cndp2 7 0.86 0.31 3.15
12 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11
13 INT106037 Gene_expression of PEPD 10 0.75 4.18 3.11
14 INT140401 Binding of PEPD 3 0.47 2.22 2.97
15 INT138016 Regulation of Naalad2 3 0.43 1.28 2.96
16 INT141559 Localization of Naalad2 2 0.55 1.14 2.65
17 INT41521 Binding of Cndp2 4 0.36 0.74 1.34
18 INT106039 Negative_regulation of Gene_expression of PEPD 5 0.56 1.37 1.18
19 INT279823 Gene_expression of Pepd 1 0.19 2 1.14
20 INT16669 Gene_expression of CNDP2 8 0.26 1.7 1.12
21 INT176609 Gene_expression of Dpep1 8 0.03 2.37 1.07
22 INT106038 Regulation of PEPD 3 0.43 3.93 1.01
23 INT28784 Positive_regulation of Gene_expression of CNDP1 3 0.22 3.87 1
24 INT119776 Positive_regulation of Negative_regulation of Naalad2 1 0.02 0.73 0.99
25 INT106036 Negative_regulation of Negative_regulation of PEPD 2 0.42 0.68 0.98
26 INT3957 Gene_expression of CNDP1 6 0.52 3.7 0.96
27 INT255304 Regulation of Binding of Dpep1 1 0.02 0 0.95
28 INT46483 Localization of Dpep1 4 0.06 1.58 0.88
29 INT11028 Binding of CNDP2 6 0.24 3.47 0.87
30 INT242750 Positive_regulation of Positive_regulation of Naalad2 1 0.08 0.34 0.86
31 INT36676 Gene_expression of Pepd 2 0.36 1.41 0.82
32 INT3958 Regulation of CNDP1 5 0.35 0.86 0.78
33 INT242751 Negative_regulation of Localization of Naalad2 1 0.07 0.32 0.74
34 INT18794 Negative_regulation of Regulation of Cndp2 1 0.37 0 0.7
35 INT36675 Negative_regulation of Pepd 3 0.47 8.99 0.63
36 INT255306 Positive_regulation of Dpep1 1 0.02 0 0.61
37 INT37610 Negative_regulation of Positive_regulation of CNDP1 1 0.01 0.22 0.59
38 INT37609 Positive_regulation of Positive_regulation of CNDP1 1 0.01 0.22 0.59
39 INT215180 Positive_regulation of CNDP2 1 0.15 0.69 0.58
40 INT242749 Negative_regulation of Binding of Naalad2 1 0.07 0.34 0.56
41 INT242752 Binding of Naalad2 1 0.06 0.33 0.55
42 INT45200 Positive_regulation of Protein_catabolism of Cndp2 1 0.40 0 0.53
43 INT119076 Positive_regulation of PEPD 3 0.63 1.15 0.52
44 INT189241 Localization of CNDP1 2 0.51 0.67 0.52
45 INT138766 Regulation of Pepd 1 0.07 0.18 0.52
46 INT255308 Negative_regulation of Binding of Dpep1 1 0.02 0 0.46
47 INT49244 Localization of Cndp2 2 0.35 0.1 0.45
48 INT246673 Negative_regulation of Pepd 1 0.05 0.26 0.34
49 INT246671 Negative_regulation of Protein_catabolism of Pepd 1 0.07 0.26 0.34
50 INT59998 Regulation of CNDP2 2 0.21 0.05 0.31
51 INT246676 Protein_catabolism of Pepd 1 0.13 0.26 0.31
52 INT227514 Regulation of Dpep1 1 0.02 0.06 0.3
53 INT59996 Localization of CNDP2 3 0.63 0.17 0.16
54 INT48515 Regulation of Gene_expression of CNDP2 1 0.16 0.09 0.15
55 INT72702 Regulation of Gene_expression of Cndp2 2 0.10 0.91 0.14
56 INT237830 Binding of CNDP1 1 0.35 1.05 0.14
57 INT85208 Negative_regulation of Protein_catabolism of Cndp2 1 0.08 0 0.12
58 INT50378 Transcription of Cndp2 1 0.01 0.15 0.11
59 INT237829 Negative_regulation of CNDP1 2 0.42 0.6 0.1
60 INT92612 Transcription of Pepd 1 0.55 1.71 0.08
61 INT167522 Binding of Pepd 1 0.24 0.44 0.08
62 INT41513 Positive_regulation of Regulation of CNDP1 1 0.00 0.07 0.07
63 INT119083 Negative_regulation of Phosphorylation of PEPD 1 0.53 0 0
64 INT119074 Phosphorylation of PEPD 1 0.75 0 0
65 INT226241 Negative_regulation of Negative_regulation of Cndp2 1 0.41 0 0
66 INT192451 Negative_regulation of Positive_regulation of Cndp2 1 0.41 0 0
67 INT352205 Positive_regulation of Gene_expression of Cndp2 1 0.11 0.64 0
68 INT352208 Negative_regulation of Gene_expression of Cndp2 1 0.10 0.64 0
69 INT312375 Transcription of CNDP2 1 0.18 0.81 0
70 INT355123 Regulation of Negative_regulation of PEPD 1 0.27 0.28 0
71 INT241848 Protein_catabolism of CNDP2 1 0.02 0.81 0
72 INT241849 Positive_regulation of Protein_catabolism of CNDP2 1 0.01 0.82 0
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