GO:0016813

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Name hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Categary Function
Go Slim No
Go Link GO:0016813
Unique Molecular Interactions 11
Total Molecular Interactions 13
Total Single Events 149
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines. They are ordered first by their pain relevance and then by number of times they were reported for hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
2 INT331927 Ptger2 Positive_regulation of Arg1 1 0.06 1.8 0.42
3 INT331768 Binding of Arg1 and NOSTRIN 1 0.01 0.6 0.17
4 INT331766 Binding of Arg1 and Nos2 1 0.17 0.6 0.17
5 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17
6 INT331924 Binding of Arg1 and Actvty1 1 0.03 1.11 0.05
7 INT239338 Arg2 Positive_regulation of RCT 1 0.01 1.15 0.03
8 INT249961 Gatm Regulation of NOS1 1 0.00 0.07 0.03
9 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0
10 INT324306 Binding of GATM and STC1 1 0.02 1.61 0
11 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines. They are ordered first by their pain relevance and then by number of times they were reported in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72
2 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13
3 INT94050 Negative_regulation of Arg1 6 0.39 6.07 2.06
4 INT94056 Positive_regulation of Gene_expression of Arg1 8 0.60 6.57 1.95
5 INT94054 Regulation of Arg1 5 0.47 5.37 1.57
6 INT331764 Regulation of Gene_expression of Arg1 7 0.36 4.65 1.1
7 INT94053 Transcription of Arg1 5 0.46 3.11 1.02
8 INT113834 Regulation of Gatm 1 0.03 0.71 0.75
9 INT94047 Negative_regulation of Gene_expression of Arg1 1 0.37 1.37 0.5
10 INT261167 Gene_expression of GATM 1 0.75 0.16 0.47
11 INT94048 Positive_regulation of Positive_regulation of Arg1 2 0.44 1.91 0.32
12 INT95065 Negative_regulation of Gatm 1 0.02 0.07 0.31
13 INT330614 Positive_regulation of Transcription of Arg1 1 0.15 0.92 0.29
14 INT239293 Gene_expression of Arg2 1 0.10 3.26 0.29
15 INT94052 Negative_regulation of Protein_catabolism of Arg1 1 0.37 0.69 0.25
16 INT94049 Protein_catabolism of Arg1 1 0.77 0.6 0.25
17 INT211657 Localization of Arg1 4 0.53 3.48 0.2
18 INT303015 Phosphorylation of Gatm 1 0.05 1 0.09
19 INT331917 Negative_regulation of Positive_regulation of Arg1 1 0.48 1.22 0.07
20 INT249946 Gene_expression of Gatm 1 0.02 0.13 0.07
21 INT249949 Negative_regulation of Gene_expression of Gatm 1 0.01 0.08 0.04
22 INT331922 Binding of Arg1 1 0.30 0.74 0.03
23 INT239276 Positive_regulation of Gene_expression of Arg2 1 0.09 1.1 0.03
24 INT144505 Negative_regulation of Arg2 1 0.35 0 0
25 INT68274 Positive_regulation of Arg2 1 0.01 0 0
26 INT249948 Positive_regulation of Gatm 1 0.02 0 0
27 INT211649 Regulation of Negative_regulation of Arg1 1 0.26 0.41 0
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