GO:0016817

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Name hydrolase activity, acting on acid anhydrides
Categary Function
Go Slim No
Go Link GO:0016817
Unique Molecular Interactions 35
Total Molecular Interactions 47
Total Single Events 332
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on acid anhydrides. They are ordered first by their pain relevance and then by number of times they were reported for hydrolase activity, acting on acid anhydrides. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
2 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
3 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
4 INT161653 Gsr Regulation of Gene_expression of Ifih1 1 0.04 1.05 0.46
5 INT168460 Sult1a1 Negative_regulation of Gene_expression of Ifih1 1 0.02 0.96 0.41
6 INT168454 Sult1a1 Negative_regulation of Ifih1 1 0.02 0.89 0.39
7 INT297738 Cbr1 Positive_regulation of Ifih1 1 0.01 1.83 0.39
8 INT282397 Binding of Irgm1 and Atg16l1 1 0.17 1.18 0.39
9 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
10 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
11 INT290314 MAVS Positive_regulation of DDX58 1 0.06 0.63 0.13
12 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1
13 INT309511 Binding of Xrcc6 and Xrcc5 1 0.18 1.18 0.08
14 INT223525 Binding of Erv4 and Chd9 1 0.17 1.2 0.07
15 INT223527 Binding of Chd9 and Li 1 0.36 1.2 0.07
16 INT223529 Erv4 Regulation of Gene_expression of Chd9 1 0.20 0.81 0.06
17 INT223522 Li Regulation of Gene_expression of Chd9 1 0.44 0.82 0.06
18 INT310306 Tlr4 Regulation of Gene_expression of Chd7 1 0.01 0.25 0.04
19 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03
20 INT268331 Binding of SNRNP70 and CHD7 1 0.01 1.91 0
21 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
22 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
23 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
24 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0
25 INT269206 Bmca Regulation of Gene_expression of Chd7 1 0.00 0.31 0
26 INT230272 RAD54L Regulation of RAD54B 1 0.01 0 0
27 INT225614 Binding of XRCC5 and Parp1 1 0.09 0 0
28 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0
29 INT323332 Binding of Ighm and Chd7 1 0.02 0 0
30 INT189374 Binding of RAD51 and Rad54l 1 0.01 0 0
31 INT332406 Negative_regulation of Irgm1 Positive_regulation of Mapk1 1 0.02 0.29 0
32 INT313687 Binding of BCR and IFIH1 1 0.09 0.23 0
33 INT265390 IFIH1 Positive_regulation of Regulation of IFNA1 1 0.00 0.08 0
34 INT297734 Cbr1 Regulation of Positive_regulation of Ifih1 1 0.00 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrolase activity, acting on acid anhydrides. They are ordered first by their pain relevance and then by number of times they were reported in hydrolase activity, acting on acid anhydrides. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
2 INT111377 Positive_regulation of Ifih1 16 0.60 11.22 6.99
3 INT124605 Gene_expression of Ifih1 16 0.57 7.36 5.33
4 INT9863 Negative_regulation of Ifih1 17 0.20 10.58 5.07
5 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
6 INT77852 Binding of Chd7 8 0.31 4.1 2.51
7 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24
8 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
9 INT127649 Regulation of Ifih1 6 0.23 4.21 1.92
10 INT78665 Gene_expression of Irgm1 12 0.65 3.17 1.83
11 INT124603 Positive_regulation of Gene_expression of Ifih1 3 0.16 1.17 1.22
12 INT178480 Positive_regulation of Irgm1 7 0.13 5.91 1.15
13 INT146030 Negative_regulation of Positive_regulation of Ifih1 2 0.29 1.16 1.13
14 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
15 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76
16 INT282385 Binding of Irgm1 2 0.20 3.18 0.7
17 INT188775 Binding of IFIH1 11 0.16 12.4 0.61
18 INT100698 Regulation of Chd7 6 0.34 1.85 0.49
19 INT313688 Regulation of IFIH1 3 0.19 4.2 0.48
20 INT238104 Binding of Ifih1 10 0.46 2.57 0.45
21 INT74864 Negative_regulation of Gene_expression of Chd7 1 0.08 0.34 0.44
22 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42
23 INT284164 Localization of Chd7 3 0.25 1.32 0.41
24 INT47625 Negative_regulation of IFIH1 4 0.51 1.68 0.39
25 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35
26 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28
27 INT112834 Regulation of Gene_expression of IFIH1 1 0.08 0.15 0.25
28 INT344156 Positive_regulation of Gene_expression of Irgm1 1 0.02 0.71 0.21
29 INT344159 Positive_regulation of Positive_regulation of Irgm1 1 0.03 0.33 0.2
30 INT9862 Positive_regulation of Negative_regulation of Ifih1 1 0.10 0.24 0.17
31 INT221105 Negative_regulation of Irgm1 3 0.13 1.31 0.13
32 INT309460 Binding of Xrcc5 1 0.16 0.09 0.08
33 INT223504 Gene_expression of Chd9 1 0.67 0.81 0.06
34 INT100697 Positive_regulation of Positive_regulation of Chd7 1 0.13 0.34 0.06
35 INT223516 Regulation of Gene_expression of Chd9 1 0.24 0.81 0.06
36 INT286296 Gene_expression of Rad54l 1 0.01 0.45 0.06
37 INT290325 Binding of DDX58 1 0.04 0.52 0.05
38 INT310293 Regulation of Positive_regulation of Chd7 1 0.04 0.36 0.05
39 INT238101 Localization of Ifih1 3 0.71 0.92 0.03
40 INT328278 Phosphorylation of IFIH1 2 0.08 1.27 0.03
41 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
42 INT268334 Positive_regulation of CHD7 1 0.42 0.96 0.03
43 INT268335 Negative_regulation of CHD7 1 0.57 0.84 0.03
44 INT226855 Localization of Irgm1 1 0.23 0 0.03
45 INT346490 Phosphorylation of DDX58 1 0.07 1.03 0.03
46 INT229890 Negative_regulation of Gene_expression of IFIH1 2 0.08 1.06 0
47 INT268339 Binding of CHD7 1 0.47 2.77 0
48 INT297727 Positive_regulation of Positive_regulation of Ifih1 1 0.02 0.27 0
49 INT348467 Positive_regulation of XRCC5 1 0.25 0.43 0
50 INT320197 Positive_regulation of Transcription of IFIH1 1 0.08 0.15 0
51 INT309467 Gene_expression of Xrcc5 1 0.26 0.1 0
52 INT309483 Positive_regulation of Xrcc5 1 0.20 0.1 0
53 INT256922 Regulation of Irgm1 1 0.03 0.91 0
54 INT230314 Transcription of RAD54L 1 0.04 0 0
55 INT230302 Gene_expression of RAD54L 1 0.04 0 0
56 INT320196 Localization of IFIH1 1 0.12 0.72 0
57 INT230300 Regulation of RAD54L 1 0.01 0.06 0
58 INT321246 Negative_regulation of Positive_regulation of Chd7 1 0.03 0 0
59 INT320193 Transcription of IFIH1 1 0.11 0.15 0
60 INT260913 Negative_regulation of Smarca4 1 0.18 0.29 0
61 INT230305 Regulation of Transcription of RAD54L 1 0.03 0 0
62 INT273916 Binding of Smarca4 1 0.01 0 0
63 INT189334 Binding of Rad54l 1 0.06 0 0
64 INT225463 Binding of XRCC5 1 0.36 0 0
65 INT320195 Positive_regulation of Binding of IFIH1 1 0.08 1.08 0
66 INT268333 Gene_expression of CHD7 1 0.75 1.83 0
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