GO:0016847

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Name 1-aminocyclopropane-1-carboxylate synthase activity
Categary Function
Go Slim No
Go Link GO:0016847
Unique Molecular Interactions 43
Total Molecular Interactions 57
Total Single Events 529
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 1-aminocyclopropane-1-carboxylate synthase activity. They are ordered first by their pain relevance and then by number of times they were reported for 1-aminocyclopropane-1-carboxylate synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
2 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
3 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
4 INT160414 Hivan1 Positive_regulation of Tat 1 0.15 0.84 0.66
5 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
6 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
7 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
8 INT248135 Binding of IDS and ACCS 1 0.09 1.12 0.51
9 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51
10 INT90252 Binding of PPBP and TAT 1 0.39 5.55 0.48
11 INT90262 Binding of TAT and Pf4 1 0.03 5.64 0.48
12 INT323907 ACCS Positive_regulation of IL4 1 0.04 0.9 0.45
13 INT323906 ACCS Positive_regulation of IL10 1 0.05 0.9 0.45
14 INT161074 Ccbl1 Negative_regulation of Gsr 1 0.00 0 0.41
15 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33
16 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
17 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
18 INT243168 Binding of CXCL5 and ACCS 1 0.11 1.25 0.29
19 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
20 INT329586 Binding of UBAP1 and ACCS 1 0.00 1.08 0.25
21 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18
22 INT213072 Binding of IFNA1 and ACCS 1 0.06 3.85 0.17
23 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17
24 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17
25 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14
26 INT319005 Binding of IL6 and ACCS 1 0.01 5.26 0.14
27 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
28 INT319004 Binding of CSF2 and ACCS 1 0.01 3.51 0.12
29 INT73585 TAT Positive_regulation of Mb 1 0.15 0.64 0.09
30 INT271349 ACCS Positive_regulation of PAPPA 1 0.06 0.87 0.09
31 INT318999 Binding of IL8 and ACCS 1 0.03 3.52 0.09
32 INT271347 Negative_regulation of Binding of TNNT2 and ACCS 1 0.01 0.67 0.08
33 INT271346 Binding of TNNT2 and ACCS 1 0.01 0.67 0.08
34 INT319001 Binding of IGHG3 and ACCS 1 0.00 1.76 0.07
35 INT191699 Binding of TAT and TAR 1 0.03 0.75 0
36 INT232516 Binding of RS1 and ACCS 1 0.00 0.74 0
37 INT191700 Positive_regulation of Binding of TAT and TAR 1 0.04 0.76 0
38 INT191698 Binding of TAT and SORBS1 1 0.01 1.08 0
39 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0
40 INT232515 Binding of SNRNP70 and ACCS 1 0.01 0.75 0
41 INT268097 Binding of FAS and ACCS 1 0.02 0.4 0
42 INT242301 Binding of EGFR and ACCS 1 0.11 1.31 0
43 INT232517 Binding of C1orf9 and ACCS 1 0.09 0.75 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 1-aminocyclopropane-1-carboxylate synthase activity. They are ordered first by their pain relevance and then by number of times they were reported in 1-aminocyclopropane-1-carboxylate synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94
2 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2
3 INT102698 Binding of ACCS 54 0.42 66.73 9.06
4 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78
5 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57
6 INT504 Gene_expression of GPT 42 0.75 27.54 3.99
7 INT106805 Localization of ACCS 15 0.53 15.22 3.98
8 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66
9 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44
10 INT141132 Regulation of ACCS 14 0.29 13.92 1.89
11 INT53451 Regulation of TAT 6 0.44 3.07 1.61
12 INT180388 Positive_regulation of Gene_expression of ACCS 9 0.21 9.43 1.34
13 INT152982 Negative_regulation of ACCS 14 0.37 9.63 1.3
14 INT17099 Regulation of GPT 9 0.44 5.5 1.2
15 INT96678 Binding of TAT 3 0.47 6.75 0.85
16 INT207421 Positive_regulation of Gene_expression of GPT 9 0.49 5.62 0.83
17 INT141591 Negative_regulation of Positive_regulation of GPT 2 0.42 0.83 0.8
18 INT242302 Negative_regulation of Gene_expression of ACCS 3 0.11 2.04 0.79
19 INT136164 Positive_regulation of Ccbl1 1 0.27 0 0.76
20 INT167680 Localization of Tat 1 0.73 0.84 0.58
21 INT51485 Localization of TAT 3 0.78 2.18 0.55
22 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54
23 INT351960 Phosphorylation of ACCS 1 0.06 1.06 0.54
24 INT351959 Regulation of Phosphorylation of ACCS 1 0.03 1.06 0.54
25 INT2812 Transcription of GPT 2 0.67 1.18 0.52
26 INT271367 Protein_catabolism of ACCS 1 0.06 2.34 0.5
27 INT331012 Negative_regulation of Localization of ACCS 1 0.15 2.05 0.45
28 INT55807 Negative_regulation of GPT 4 0.42 4.11 0.44
29 INT136167 Negative_regulation of Binding of Ccbl1 1 0.25 0 0.39
30 INT136169 Binding of Ccbl1 1 0.22 0 0.39
31 INT161073 Gene_expression of Ccbl1 1 0.01 0 0.34
32 INT274704 Localization of GPT 5 0.73 3.91 0.29
33 INT335119 Regulation of Transcription of GPT 1 0.08 0.56 0.27
34 INT268283 Negative_regulation of Positive_regulation of ACCS 1 0.03 0.89 0.25
35 INT44540 Binding of GPT 3 0.36 6.14 0.23
36 INT268100 Regulation of Gene_expression of ACCS 2 0.06 1.81 0.23
37 INT277033 Positive_regulation of Positive_regulation of ACCS 2 0.15 1.69 0.21
38 INT159088 Gene_expression of Tat 1 0.75 1.43 0.15
39 INT154678 Positive_regulation of Gene_expression of TAT 2 0.49 1.7 0.12
40 INT298577 Negative_regulation of Negative_regulation of GPT 1 0.02 1.76 0.12
41 INT331011 Positive_regulation of Binding of ACCS 1 0.18 1.1 0.09
42 INT342261 Positive_regulation of Localization of GPT 2 0.49 0.95 0.07
43 INT186002 Transcription of ACCS 1 0.05 1 0.07
44 INT191701 Regulation of Binding of TAT 1 0.26 0.43 0.04
45 INT273143 Negative_regulation of Tat 1 0.01 2.3 0
46 INT344588 Negative_regulation of Gene_expression of GPT 1 0.41 0.62 0
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