GO:0016853

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Name isomerase activity
Categary Function
Go Slim Yes
Go Link GO:0016853
Unique Molecular Interactions 462
Total Molecular Interactions 642
Total Single Events 5462
Pain Genes Associated 75

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for isomerase activity. They are ordered first by their pain relevance and then by number of times they were reported for isomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT64756 oh Negative_regulation of Gpi1 1 0.03 0 4.09
3 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
4 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
5 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
6 INT254243 Binding of HOMER1 and MRI1 1 0.03 1.99 1.57
7 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
8 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41
9 INT64758 Negative_regulation of oh Negative_regulation of Gpi1 1 0.03 0 1.24
10 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
11 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
12 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
13 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
14 INT161512 Ppig Negative_regulation of Positive_regulation of S100a8 1 0.02 0.23 1.12
15 INT168185 Binding of PLXNA2 and MRI1 1 0.25 0.78 1.08
16 INT76150 Das Negative_regulation of Gpi1 1 0.03 0 0.99
17 INT25111 Binding of PTGDS and PLEKHM1 1 0.01 0 0.97
18 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96
19 INT126766 Binding of PTGDS and PTGDR2 4 0.40 1.62 0.93
20 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
21 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
22 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
23 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
24 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
25 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
26 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
27 INT90959 PPIG Regulation of CYP2C9 1 0.43 0 0.75
28 INT147620 Gpi Positive_regulation of Localization of Calca 1 0.10 0 0.75
29 INT155139 Binding of MC1R and PTGES 3 0.09 0 0.7
30 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
31 INT65426 Sigmar1 Regulation of Gpi1 1 0.21 0 0.7
32 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69
33 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
34 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69
35 INT76089 IFNA1 Negative_regulation of Positive_regulation of ISYNA1 1 0.27 0.05 0.65
36 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
37 INT38905 Ptgfr Regulation of Ptgds 1 0.20 0 0.63
38 INT76087 IFNA1 Negative_regulation of ISYNA1 1 0.27 0.06 0.63
39 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 0.44 0.13 0.62
40 INT64755 Regulation of oh Negative_regulation of Gpi1 1 0.02 0 0.61
41 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
42 INT63525 Cpe Positive_regulation of Gpi1 1 0.03 0 0.59
43 INT77379 Tmie Negative_regulation of Ebp 1 0.03 0 0.59
44 INT5416 Negative_regulation of Penk Positive_regulation of Pdia4 1 0.03 0.09 0.58
45 INT188471 Binding of Gpi1 and Arhgap4 1 0.07 1.61 0.58
46 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57
47 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
48 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
49 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
50 INT136758 TNF Positive_regulation of Gene_expression of PTGES 1 0.05 0.52 0.55
51 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
52 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
53 INT29070 Binding of Isyna1 and LOC100360765 1 0.04 0 0.53
54 INT77098 Nlrp1a Negative_regulation of Positive_regulation of Ppig 1 0.47 0.68 0.53
55 INT312662 Binding of CSTF2 and DSE 1 0.06 0.1 0.53
56 INT29074 Binding of Isyna1 and AA2 1 0.03 0 0.53
57 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
58 INT5417 Penk Positive_regulation of Pdia4 1 0.03 0.09 0.52
59 INT261498 CBS Positive_regulation of DSE 1 0.00 0 0.5
60 INT12897 Penk Regulation of Pdia4 1 0.07 0 0.5
61 INT312118 ELANE Regulation of PTGES 1 0.22 0.92 0.49
62 INT162329 Tmc1 Negative_regulation of Gene_expression of Ptges2 1 0.03 0.58 0.47
63 INT92802 Binding of PPIG and GRHPR 1 0.03 0.11 0.47
64 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47
65 INT64757 oh Positive_regulation of Negative_regulation of Gpi1 1 0.03 0 0.47
66 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
67 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
68 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
69 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
70 INT317427 IFN1@ Positive_regulation of ISYNA1 1 0.12 0.49 0.45
71 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44
72 INT103028 Calca Positive_regulation of Gene_expression of Ptgis 1 0.17 0.58 0.44
73 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
74 INT234599 Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44
75 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
76 INT234600 Negative_regulation of Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44
77 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
78 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43
79 INT261472 Binding of SPTBN1 and Gpi1 1 0.00 0.69 0.42
80 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
81 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41
82 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
83 INT333512 Binding of GPI and MCF2L 1 0.09 0.75 0.41
84 INT264522 Binding of GPER and PTGDS 1 0.03 1.22 0.4
85 INT264525 Binding of PTGDS and PTGFR 1 0.02 1.22 0.39
86 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
87 INT37270 Negative_regulation of Ebp Positive_regulation of LH 1 0.37 0 0.38
88 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38
89 INT264527 IL1B Positive_regulation of Gene_expression of PTGDS 1 0.07 0.75 0.38
90 INT109683 NOS1 Positive_regulation of Positive_regulation of ISYNA1 1 0.01 0.11 0.38
91 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37
92 INT59845 Negative_regulation of IFNA1 Positive_regulation of Gpi1 1 0.09 0 0.37
93 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37
94 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37
95 INT144043 IL13 Positive_regulation of PTGES 1 0.32 0.43 0.37
96 INT59844 IFNA1 Positive_regulation of Gpi1 1 0.10 0 0.37
97 INT106511 Binding of Cpox and Ptges3 2 0.01 0.7 0.36
98 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36
99 INT202810 Pin1 Regulation of Csf2 1 0.03 0.82 0.36
100 INT255555 Binding of Ptgds and Tfdp1 1 0.14 1.14 0.36
101 INT126767 Positive_regulation of Binding of PTGDS and PTGDR2 1 0.54 0.3 0.35
102 INT144046 IL13 Negative_regulation of Gene_expression of PTGES 1 0.30 0.48 0.35
103 INT312124 EGR1 Regulation of Binding of PTGES 1 0.31 0.41 0.35
104 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35
105 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
106 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35
107 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35
108 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35
109 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
110 INT51480 Gtpc Positive_regulation of Pdia4 1 0.04 0 0.34
111 INT264521 PTGDS Negative_regulation of Positive_regulation of MMP1 1 0.06 1.42 0.34
112 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33
113 INT312119 ELANE Positive_regulation of Gene_expression of PTGES 1 0.18 0.74 0.33
114 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33
115 INT311263 RENBP Regulation of TNF 1 0.01 1.59 0.33
116 INT109901 RPE Positive_regulation of Positive_regulation of MAP3K14 1 0.54 0.15 0.33
117 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
118 INT109902 RPE Positive_regulation of Gene_expression of CCL16 1 0.07 0.15 0.33
119 INT147984 Ptgds Positive_regulation of Cpox 1 0.17 0.29 0.32
120 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32
121 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
122 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
123 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
124 INT147982 Cpox Positive_regulation of Gene_expression of Ptgds 1 0.17 0.3 0.32
125 INT76086 IRF6 Positive_regulation of ISYNA1 1 0.07 0.18 0.31
126 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
127 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
128 INT76090 IFNA1 Positive_regulation of ISYNA1 1 0.30 0.18 0.31
129 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
130 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
131 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
132 INT46339 Ptgds Regulation of Localization of Lh 1 0.25 0 0.29
133 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29
134 INT67529 PTGDS Positive_regulation of Positive_regulation of IL6 1 0.30 0.69 0.29
135 INT348137 Binding of GYPE and Gpi 1 0.01 1.29 0.29
136 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
137 INT168809 Nfkb1 Positive_regulation of Transcription of Trub1 1 0.02 0.44 0.28
138 INT334737 Binding of Oprd1 and Gpi 1 0.01 0.71 0.28
139 INT136759 TNF Positive_regulation of PTGES 1 0.03 0.29 0.28
140 INT102923 Ptgds Regulation of Avp 1 0.02 0 0.27
141 INT142450 B4GALNT1 Regulation of Gene_expression of PTGIS 1 0.02 0.24 0.27
142 INT269459 Binding of ISYNA1 and HHIP 1 0.00 0 0.27
143 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
144 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
145 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
146 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27
147 INT107615 IL1B Positive_regulation of PTGES 2 0.55 0.05 0.26
148 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
149 INT323926 MRM1 Positive_regulation of MRI1 1 0.04 0.44 0.26
150 INT19839 Positive_regulation of Binding of Ptgis and Tbxa2r 1 0.00 0.2 0.26
151 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
152 INT348924 Mmp1 Regulation of Gene_expression of Renbp 1 0.03 0.95 0.26
153 INT181976 TNF Regulation of Transcription of Gpi1 1 0.00 0.64 0.26
154 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
155 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
156 INT19840 Binding of Ptgis and Tbxa2r 1 0.00 0.2 0.25
157 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25
158 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
159 INT352890 Binding of PTGDS and ROS1 1 0.13 0.67 0.25
160 INT355567 IRF6 Positive_regulation of MIF 1 0.01 0.29 0.25
161 INT312115 ELANE Positive_regulation of Transcription of PTGES 1 0.25 0.53 0.25
162 INT105542 PTGES Positive_regulation of DNTT 1 0.00 0.62 0.25
163 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
164 INT182043 Binding of Gpi1 and IgG 1 0.13 0.94 0.25
165 INT181977 TNF Regulation of Gene_expression of Gpi1 1 0.00 0.64 0.25
166 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24
167 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24
168 INT235088 NOS1 Regulation of ISYNA1 1 0.07 0.75 0.23
169 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
170 INT303985 Il1 Positive_regulation of Gene_expression of ISYNA1 1 0.01 0.54 0.23
171 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22
172 INT264524 PTGDS Negative_regulation of Gene_expression of MMP1 1 0.09 0.5 0.22
173 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
174 INT69869 Binding of Ptgdr and Ptgds 1 0.06 0 0.22
175 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
176 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22
177 INT264526 PTGDS Negative_regulation of Gene_expression of MMP13 1 0.12 0.5 0.22
178 INT149882 Binding of Ptgs1 and Ptges 1 0.01 0.15 0.22
179 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
180 INT223570 Binding of Mri1 and Uhrf2 1 0.02 0.56 0.22
181 INT264517 PTGDS Positive_regulation of TFDP1 1 0.17 0.5 0.22
182 INT223569 Binding of cy and Mri1 1 0.00 0.57 0.22
183 INT142446 Regulation of CPOX Regulation of Gene_expression of PTGIS 1 0.10 0.26 0.22
184 INT264519 PTGDS Negative_regulation of Positive_regulation of TFDP1 1 0.15 0.5 0.22
185 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
186 INT142448 TNF Positive_regulation of Localization of PTGIS 1 0.35 0.28 0.21
187 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
188 INT313655 ISYNA1 Regulation of COX18 1 0.01 0.08 0.2
189 INT181646 interleukin-17 Positive_regulation of ISYNA1 1 0.01 0.26 0.2
190 INT235084 IL6 Positive_regulation of Gene_expression of ISYNA1 1 0.02 1.11 0.2
191 INT313648 ISYNA1 Regulation of GOPC 1 0.02 0.08 0.2
192 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2
193 INT59459 Binding of OXTR and ISYNA1 1 0.05 0.47 0.2
194 INT333510 Positive_regulation of STON1 Positive_regulation of GPI 1 0.10 0.38 0.19
195 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
196 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
197 INT165555 Hypt Regulation of Gene_expression of Ptges2 1 0.30 0.87 0.19
198 INT139877 CPOX Regulation of Gene_expression of PTGES 1 0.17 0.07 0.18
199 INT139881 CPOX Regulation of Transcription of PTGES 1 0.17 0.07 0.18
200 INT69868 Binding of Ptgds and Ptger1 1 0.01 0 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for isomerase activity. They are ordered first by their pain relevance and then by number of times they were reported in isomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48
2 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98
3 INT116737 Localization of Mif 63 0.81 52.97 28.11
4 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26
5 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86
6 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68
7 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01
8 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67
9 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
10 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19
11 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
12 INT180497 Binding of MRI1 45 0.42 28.35 14.77
13 INT28510 Positive_regulation of Gpi 21 0.68 6.75 14.27
14 INT70265 Regulation of MRI1 42 0.39 30.95 14.18
15 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87
16 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54
17 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48
18 INT15011 Positive_regulation of Gpi1 29 0.47 12.47 13.48
19 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45
20 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
21 INT28420 Gene_expression of Ptgds 59 0.78 31.72 12.67
22 INT50580 Binding of PPIG 39 0.36 11.17 12.34
23 INT91413 Negative_regulation of PTGES 35 0.58 17.94 12.03
24 INT72949 Binding of Mif 31 0.46 23.12 11.65
25 INT4804 Positive_regulation of Gene_expression of PTGDS 10 0.68 21.43 11.14
26 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93
27 INT106510 Gene_expression of Ptges 70 0.75 36.18 9.75
28 INT59465 Negative_regulation of ISYNA1 41 0.49 21.9 9.46
29 INT23147 Negative_regulation of MRI1 26 0.38 14.33 8.96
30 INT117553 Regulation of MIF 10 0.56 12.76 8.67
31 INT71763 Gene_expression of Mri1 33 0.58 12.56 8.6
32 INT69866 Positive_regulation of Ptgds 26 0.70 16.25 8.33
33 INT156827 Localization of MRI1 25 0.65 16.06 8.33
34 INT5114 Gene_expression of Ptgis 41 0.50 21.43 8.1
35 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
36 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64
37 INT73508 Negative_regulation of Gene_expression of ISYNA1 32 0.51 19.67 7.57
38 INT4810 Localization of PTGDS 20 0.81 4.19 6.97
39 INT15012 Regulation of Gpi1 18 0.60 11.64 6.91
40 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84
41 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71
42 INT211701 Positive_regulation of Mri1 20 0.34 20.64 6.69
43 INT9818 Positive_regulation of Pdia4 12 0.34 0.67 6.65
44 INT517 Regulation of Mif 16 0.62 5.43 6.55
45 INT211363 Positive_regulation of RENBP 13 0.22 13.26 6.48
46 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45
47 INT142904 Negative_regulation of Ptges2 14 0.47 9.49 6.15
48 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
49 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
50 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91
51 INT71764 Positive_regulation of Mri1 24 0.44 12.31 5.67
52 INT162328 Regulation of Ptges2 21 0.19 12.07 5.56
53 INT98685 Positive_regulation of Gene_expression of PTGES 28 0.68 9.46 5.55
54 INT7996 Gene_expression of Ptgds 18 0.64 6.47 5.51
55 INT35248 Gene_expression of Gpi 14 0.51 2.38 5.49
56 INT143925 Negative_regulation of Ptges 18 0.42 10.5 5.18
57 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
58 INT19934 Negative_regulation of Ptgis 18 0.32 6.18 5.03
59 INT134297 Positive_regulation of Gene_expression of Ptges2 22 0.41 13.12 4.97
60 INT23284 Negative_regulation of Gpi 5 0.58 1.84 4.96
61 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
62 INT131176 Gene_expression of Srr 8 0.64 3.29 4.81
63 INT62291 Gene_expression of PTGES2 14 0.68 8.34 4.75
64 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
65 INT118926 Regulation of PTGES 17 0.51 5.79 4.69
66 INT59464 Regulation of ISYNA1 21 0.43 12.15 4.63
67 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
68 INT54739 Negative_regulation of Negative_regulation of Gpi1 4 0.42 0.34 4.44
69 INT45725 Binding of Pdia3 8 0.47 3.61 4.42
70 INT50581 Regulation of PPIG 26 0.55 8.96 4.32
71 INT107620 Binding of PTGES 25 0.48 5.49 4.24
72 INT27758 Positive_regulation of PTGDS 20 0.67 10.74 4.22
73 INT131178 Positive_regulation of Srr 4 0.56 4.78 3.91
74 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87
75 INT66242 Gene_expression of Ptgis 15 0.64 6.73 3.84
76 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8
77 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8
78 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
79 INT112 Gene_expression of Pdia3 11 0.74 0.18 3.74
80 INT181922 Binding of RENBP 16 0.36 13.92 3.71
81 INT67724 Regulation of Gene_expression of ISYNA1 14 0.51 5.99 3.62
82 INT6994 Binding of Ptgds 15 0.36 7.06 3.54
83 INT50143 Negative_regulation of Gene_expression of Ptgds 10 0.48 5.82 3.54
84 INT108814 Regulation of Gene_expression of PTGES 8 0.59 3.62 3.54
85 INT134413 Gene_expression of HPGDS 20 0.77 8.93 3.28
86 INT164087 Gene_expression of TPI1 42 0.78 5.39 3.21
87 INT139355 Regulation of Gene_expression of Ptges2 11 0.17 6.37 3.19
88 INT198495 Gene_expression of Ranbp2 1 0.78 3.31 3.14
89 INT76092 Localization of ISYNA1 10 0.66 7.72 3.11
90 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
91 INT58756 Binding of GPI 10 0.48 7.17 3
92 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91
93 INT163290 Binding of MIF 9 0.31 7.57 2.8
94 INT41874 Positive_regulation of GPI 9 0.49 9.97 2.79
95 INT50149 Positive_regulation of Gene_expression of Ptgds 12 0.61 4.88 2.73
96 INT134145 Negative_regulation of Gene_expression of PTGES 11 0.51 5.32 2.73
97 INT203137 Binding of Mif 6 0.31 9.46 2.71
98 INT120011 Localization of MIF 6 0.58 5.72 2.6
99 INT182034 Binding of Gpi1 10 0.39 8.76 2.59
100 INT103238 Localization of PTGES 7 0.68 4.16 2.59
101 INT91349 Negative_regulation of Binding of Pdia3 1 0.57 1.12 2.59
102 INT25119 Binding of PTGDS 9 0.35 3.86 2.54
103 INT139354 Negative_regulation of Gene_expression of Ptges2 11 0.23 4.28 2.51
104 INT8782 Regulation of Gpi 5 0.28 1.63 2.51
105 INT63524 Localization of Gpi1 10 0.61 5.42 2.49
106 INT61907 Negative_regulation of Ebp 9 0.37 4.77 2.49
107 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
108 INT106513 Gene_expression of Ptges3 7 0.73 3.57 2.42
109 INT50139 Regulation of Gene_expression of Ptgds 6 0.50 3.5 2.39
110 INT153108 Transcription of Srr 4 0.57 1.41 2.38
111 INT92156 Positive_regulation of Gene_expression of Pus10 2 0.04 1.31 2.37
112 INT202792 Negative_regulation of Pin1 1 0.56 3.77 2.37
113 INT149975 Negative_regulation of Ppif 1 0.41 0.44 2.36
114 INT186094 Binding of Mri1 14 0.20 7.8 2.35
115 INT204175 Localization of Mri1 12 0.60 2.73 2.35
116 INT217253 Positive_regulation of Positive_regulation of PPIG 2 0.08 0.55 2.33
117 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
118 INT237252 Localization of Mri1 7 0.45 4.42 2.23
119 INT131177 Regulation of Gene_expression of Srr 3 0.51 0.4 2.22
120 INT94060 Transcription of ISYNA1 18 0.43 6.7 2.18
121 INT14596 Localization of Ptgds 11 0.73 4.41 2.12
122 INT164085 Positive_regulation of Gene_expression of TPI1 4 0.60 0.06 2.09
123 INT108982 Regulation of Gene_expression of Ptgds 6 0.51 1.64 2.07
124 INT106508 Positive_regulation of Gene_expression of Ptges 12 0.20 5.37 2.06
125 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
126 INT103095 Binding of ISYNA1 10 0.28 6.17 2.03
127 INT119680 Positive_regulation of Pdia3 4 0.31 2.36 1.97
128 INT66237 Positive_regulation of Ptgis 5 0.33 1.49 1.96
129 INT66240 Localization of Ptgis 9 0.58 1.36 1.95
130 INT76097 Negative_regulation of Positive_regulation of ISYNA1 5 0.31 2.47 1.95
131 INT117470 Positive_regulation of Positive_regulation of ISYNA1 7 0.51 6.87 1.94
132 INT5415 Negative_regulation of Pdia4 6 0.36 0.94 1.93
133 INT12895 Negative_regulation of Positive_regulation of Pdia4 2 0.14 0 1.91
134 INT62290 Positive_regulation of Gene_expression of PTGES2 5 0.28 3.14 1.88
135 INT20094 Binding of Pdia3 3 0.31 1.26 1.87
136 INT22448 Regulation of GPI 4 0.33 1.95 1.85
137 INT103024 Positive_regulation of Gene_expression of Ptgis 5 0.48 4.02 1.83
138 INT29067 Positive_regulation of Isyna1 3 0.22 0 1.83
139 INT97073 Positive_regulation of Ebp 6 0.42 2.68 1.8
140 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
141 INT19831 Binding of Ptgis 3 0.08 3.33 1.77
142 INT15916 Positive_regulation of Ptgis 11 0.39 6.6 1.74
143 INT184154 Transcription of Ptges2 4 0.20 2.4 1.71
144 INT104220 Positive_regulation of Gene_expression of PPIG 14 0.49 7.38 1.7
145 INT108252 Positive_regulation of Renbp 16 0.24 11.66 1.68
146 INT118700 Positive_regulation of Ptges 12 0.49 5.04 1.68
147 INT16686 Regulation of Pdia4 2 0.09 0.26 1.68
148 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
149 INT131179 Positive_regulation of Gene_expression of Srr 4 0.57 0.87 1.63
150 INT112418 Gene_expression of FKBP5 3 0.43 1.97 1.62
151 INT27438 Negative_regulation of Ptgds 3 0.51 0.24 1.61
152 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
153 INT215987 Regulation of Mri1 4 0.30 2.1 1.54
154 INT28425 Regulation of Ptgds 4 0.28 2.07 1.53
155 INT118699 Binding of Ptges 4 0.33 1.15 1.5
156 INT125800 Gene_expression of P4HB 5 0.47 5.4 1.47
157 INT37441 Localization of Ptgis 7 0.10 5.02 1.43
158 INT112420 Negative_regulation of Gene_expression of FKBP5 1 0.16 0.85 1.42
159 INT182035 Positive_regulation of Gene_expression of Gpi1 5 0.36 4.95 1.4
160 INT93735 Gene_expression of P4hb 6 0.49 4.63 1.39
161 INT179644 Gene_expression of RENBP 26 0.35 13.74 1.38
162 INT92157 Gene_expression of Pus10 2 0.05 0.95 1.38
163 INT92161 Positive_regulation of Pus10 2 0.03 0.95 1.38
164 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
165 INT6991 Negative_regulation of Ptgds 5 0.55 3.83 1.32
166 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31
167 INT29068 Positive_regulation of Positive_regulation of Isyna1 3 0.22 0 1.29
168 INT114822 Negative_regulation of PPP2R4 2 0.57 1.89 1.28
169 INT139886 Gene_expression of PTGES3 11 0.72 1.5 1.27
170 INT44917 Negative_regulation of Gene_expression of PTGDS 6 0.50 2.98 1.27
171 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
172 INT15010 Negative_regulation of Positive_regulation of Gpi1 2 0.27 0 1.27
173 INT146381 Localization of Ptges 3 0.10 5.55 1.26
174 INT106509 Negative_regulation of Gene_expression of Ptges 6 0.17 1.95 1.25
175 INT153106 Regulation of Transcription of Srr 1 0.37 0 1.25
176 INT293709 Regulation of Gene_expression of Gpi 2 0.10 0.23 1.24
177 INT41418 Regulation of Mif 2 0.40 3.86 1.24
178 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22
179 INT5115 Negative_regulation of Gene_expression of Ptgis 9 0.33 3.33 1.2
180 INT237247 Regulation of Mri1 6 0.27 4.64 1.2
181 INT68359 Positive_regulation of HPGDS 9 0.32 4.63 1.18
182 INT93619 Localization of PTGES2 2 0.04 1.88 1.17
183 INT121368 Transcription of Mif 5 0.72 2.71 1.15
184 INT153111 Positive_regulation of Transcription of Srr 2 0.41 1.41 1.15
185 INT252582 Positive_regulation of Gene_expression of Ppig 3 0.12 2.62 1.13
186 INT156804 Transcription of Ebp 1 0.41 0.49 1.13
187 INT108246 Regulation of Renbp 5 0.21 4.66 1.12
188 INT139885 Transcription of PTGES 4 0.68 1.46 1.12
189 INT204170 Binding of Mri1 5 0.22 4.45 1.11
190 INT168675 Binding of P4HB 3 0.20 1.98 1.11
191 INT33803 Positive_regulation of Ptgds 4 0.50 1.09 1.1
192 INT121375 Transcription of MIF 4 0.62 2.85 1.1
193 INT89524 Transcription of Ptgds 3 0.46 1.34 1.09
194 INT143208 Negative_regulation of TPI1 30 0.59 7.54 1.08
195 INT10033 Localization of PTGIS 10 0.69 6.8 1.07
196 INT156805 Gene_expression of Ebp 6 0.40 6.09 1.07
197 INT142777 Phosphorylation of PPP2R4 2 0.61 1.03 1.07
198 INT142776 Positive_regulation of Phosphorylation of PPP2R4 1 0.45 1.04 1.07
199 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
200 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04
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