GO:0016890

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Name site-specific endodeoxyribonuclease activity, specific for altered base
Categary Function
Go Slim No
Go Link GO:0016890
Unique Molecular Interactions 11
Total Molecular Interactions 17
Total Single Events 66
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for site-specific endodeoxyribonuclease activity, specific for altered base. They are ordered first by their pain relevance and then by number of times they were reported for site-specific endodeoxyribonuclease activity, specific for altered base. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
2 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
3 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
4 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
5 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
6 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
7 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
8 INT89763 Positive_regulation of APEX1 Positive_regulation of Positive_regulation of NR4A1 1 0.10 0.87 0.14
9 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08
10 INT287814 Apex1 Positive_regulation of Gene_expression of Rnf128 1 0.03 0.15 0.03
11 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for site-specific endodeoxyribonuclease activity, specific for altered base. They are ordered first by their pain relevance and then by number of times they were reported in site-specific endodeoxyribonuclease activity, specific for altered base. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131808 Localization of Apex1 2 0.16 13.46 4.61
2 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
3 INT253750 Positive_regulation of Gene_expression of Apex1 1 0.10 1.43 0.64
4 INT182073 Binding of APEX1 4 0.12 1.72 0.32
5 INT227426 Positive_regulation of Apex1 2 0.08 1.98 0.23
6 INT253752 Negative_regulation of Localization of Apex1 1 0.08 1.26 0.2
7 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19
8 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12
9 INT190501 Regulation of Apex1 1 0.12 0.32 0.1
10 INT273338 Protein_catabolism of Apex1 4 0.05 0.57 0.09
11 INT182080 Localization of APEX1 2 0.57 2.3 0.05
12 INT214043 Positive_regulation of Localization of APEX1 1 0.38 0.64 0.05
13 INT182079 Negative_regulation of APEX1 5 0.18 1.75 0
14 INT182075 Negative_regulation of Positive_regulation of APEX1 1 0.13 0.63 0
15 INT182072 Regulation of APEX1 1 0.08 0.76 0
16 INT214034 Positive_regulation of Gene_expression of APEX1 1 0.53 0.85 0
17 INT310100 Transcription of APEX1 1 0.09 0 0
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