GO:0016907

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Name G-protein coupled acetylcholine receptor activity
Categary Function
Go Slim No
Go Link GO:0016907
Unique Molecular Interactions 112
Total Molecular Interactions 127
Total Single Events 1086
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled acetylcholine receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for G-protein coupled acetylcholine receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT46645 Binding of Gabrg1 and Chrm5 1 0.29 0.09 1
2 INT74852 Chrm1 Positive_regulation of Localization of Abat 1 0.11 0 0.66
3 INT71839 Chrm3 Positive_regulation of Qrfp 1 0.09 0 0.47
4 INT265142 Prkcg Regulation of Localization of Chrm1 1 0.04 0 0.34
5 INT265147 Prkcg Regulation of Gene_expression of Chrm1 1 0.04 0 0.33
6 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
7 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
8 INT55641 Binding of CHRM1 and Adra2a 1 0.00 0 0.24
9 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
10 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
11 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22
12 INT350348 Binding of Car1 and Chrm1 1 0.09 0 0.2
13 INT60417 Chrm1 Regulation of Localization of Acot1 1 0.13 0 0.19
14 INT326940 Chrm3 Positive_regulation of Nalcn 1 0.06 0.21 0.19
15 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
16 INT303743 Positive_regulation of Binding of Ins1 and Chrm1 1 0.07 1.04 0.15
17 INT302930 Binding of Pnp and Chrm2 1 0.00 0.64 0.15
18 INT303744 Binding of Chrm3 and Ins1 1 0.04 1.03 0.15
19 INT303746 Binding of Ins1 and Chrm1 1 0.05 1.03 0.15
20 INT303745 Positive_regulation of Binding of Chrm3 and Ins1 1 0.05 1.04 0.15
21 INT303747 Binding of Chrm3 and Chrm1 1 0.03 1.02 0.15
22 INT227953 Chrm2 Regulation of Chrm5 1 0.21 0.33 0.13
23 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13
24 INT227957 Chrm4 Regulation of Localization of Drd2 1 0.19 0.38 0.13
25 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13
26 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13
27 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13
28 INT227959 Drd2 Regulation of Chrm4 1 0.08 0.38 0.13
29 INT227954 Chrm4 Regulation of Chrm5 1 0.24 0.33 0.13
30 INT350349 Binding of Chrm1 and Csnk2a2 1 0.11 0.09 0.09
31 INT350347 Negative_regulation of Prkca Negative_regulation of Chrm1 1 0.08 0 0.03
32 INT350346 Negative_regulation of Prkca Negative_regulation of Negative_regulation of Chrm1 1 0.08 0 0.03
33 INT350341 Negative_regulation of Prkca Negative_regulation of Localization of Chrm1 1 0.08 0 0.03
34 INT282799 Chrm2 Positive_regulation of Chrm3 1 0.16 0.29 0.03
35 INT126110 Chrng Positive_regulation of Chrm1 1 0.00 0.1 0
36 INT228117 Chrm2 Positive_regulation of Positive_regulation of Il10 1 0.22 0.61 0
37 INT287072 Chrm2 Positive_regulation of Gene_expression of Irf4 1 0.18 0.06 0
38 INT287058 Chrm2 Regulation of Positive_regulation of Igis1 1 0.03 0.09 0
39 INT126111 Chrm1 Positive_regulation of Chrng 1 0.00 0.1 0
40 INT287059 Gopc Positive_regulation of Positive_regulation of Chrm2 1 0.11 0.15 0
41 INT287077 Chrm2 Positive_regulation of Homer1 1 0.05 0.08 0
42 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0
43 INT84499 Chrm3 Positive_regulation of Ephb1 1 0.40 0 0
44 INT287076 Chrm2 Regulation of Irf4 1 0.10 0.09 0
45 INT228109 Binding of Atm and Chrm2 1 0.09 0.21 0
46 INT287061 Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.14 0.15 0
47 INT302927 Binding of Spna1 and Chrm2 1 0.00 0.35 0
48 INT228115 Gene_expression of Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.16 0.26 0
49 INT209631 INCENP Negative_regulation of CHRM1 1 0.00 0.43 0
50 INT228114 Chrm2 Positive_regulation of Gene_expression of Il10 1 0.22 0.61 0
51 INT287070 Gene_expression of Chrm2 Positive_regulation of Gene_expression of Il6 1 0.06 0.33 0
52 INT287063 Chrm2 Positive_regulation of Gopc 1 0.10 0.06 0
53 INT196212 Binding of CHRM4 and L1RE1 1 0.20 0.07 0
54 INT84498 Negative_regulation of Chrm3 Positive_regulation of Ephb1 1 0.34 0 0
55 INT287066 Chrm2 Positive_regulation of Irf4 1 0.18 0.29 0
56 INT202892 Chrm3 Regulation of Negative_regulation of Camk4 1 0.02 0.37 0
57 INT209640 INCENP Negative_regulation of Gene_expression of CHRM1 1 0.00 0.91 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled acetylcholine receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in G-protein coupled acetylcholine receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT35284 Positive_regulation of Chrm1 14 0.67 5.64 10.11
2 INT71263 Gene_expression of Chrm1 13 0.22 9.56 6.24
3 INT167600 Gene_expression of Chrm5 15 0.72 2.4 5.48
4 INT148402 Gene_expression of Chrm2 95 0.54 24.25 5.27
5 INT265160 Localization of Chrm1 1 0.16 0.66 3.16
6 INT265172 Negative_regulation of Chrm1 1 0.09 0.29 3.01
7 INT265168 Regulation of Chrm1 5 0.10 1.71 2.98
8 INT212822 Negative_regulation of Chrm5 5 0.42 0.86 2.96
9 INT123306 Negative_regulation of Positive_regulation of Chrm1 3 0.32 0.72 2.63
10 INT29792 Positive_regulation of Chrm1 9 0.15 2.05 2.59
11 INT71267 Negative_regulation of Gene_expression of Chrm1 3 0.17 3.22 2.5
12 INT15201 Positive_regulation of CHRM1 8 0.54 2.14 2.35
13 INT71265 Positive_regulation of Gene_expression of Chrm1 2 0.15 0.35 2.3
14 INT45392 Regulation of CHRM1 3 0.26 0.52 2.25
15 INT212819 Regulation of Chrm5 2 0.44 1.64 2.22
16 INT148403 Positive_regulation of Chrm2 17 0.42 7.74 2.19
17 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17
18 INT33170 Binding of Chrm1 11 0.48 1.58 2.1
19 INT25737 Regulation of Chrm1 6 0.40 1.4 2
20 INT55640 Gene_expression of CHRM1 7 0.44 2.24 1.89
21 INT110041 Gene_expression of CHRM4 5 0.52 0.72 1.57
22 INT106831 Negative_regulation of Regulation of CHRM1 1 0.15 0.16 1.49
23 INT13730 Negative_regulation of CHRM1 5 0.35 1.78 1.41
24 INT265159 Positive_regulation of Localization of Chrm1 1 0.11 0.18 1.31
25 INT265150 Regulation of Gene_expression of Chrm1 3 0.13 1.3 1.22
26 INT74849 Positive_regulation of Chrm3 5 0.64 1.71 1.2
27 INT212818 Binding of Chrm5 5 0.35 1.34 1.15
28 INT110042 Binding of CHRM4 1 0.25 0.55 1.15
29 INT57847 Gene_expression of Chrm1 12 0.69 3.55 1.12
30 INT172503 Binding of Chrm1 2 0.10 2.51 1.07
31 INT166859 Regulation of Positive_regulation of Chrm1 2 0.31 0.11 1.07
32 INT265164 Regulation of Regulation of Chrm1 1 0.10 0 1.07
33 INT95028 Gene_expression of Chrm4 8 0.39 2.66 0.99
34 INT106960 Gene_expression of Chrm3 15 0.69 6.29 0.96
35 INT148401 Regulation of Chrm3 3 0.19 1.19 0.91
36 INT212820 Transcription of Chrm5 1 0.68 0.36 0.91
37 INT73950 Negative_regulation of Chrm3 1 0.41 0 0.88
38 INT40639 Binding of CHRM1 2 0.26 0.43 0.87
39 INT193042 Positive_regulation of Gene_expression of Chrm2 15 0.28 3.93 0.86
40 INT97272 Positive_regulation of Positive_regulation of Chrm1 2 0.34 0.3 0.85
41 INT212817 Regulation of Regulation of Chrm5 1 0.44 0.13 0.81
42 INT193060 Gene_expression of CHRM2 9 0.51 2.09 0.79
43 INT228105 Negative_regulation of Gene_expression of Chrm2 5 0.25 3.17 0.75
44 INT227949 Negative_regulation of Chrm2 8 0.25 4.23 0.73
45 INT62786 Negative_regulation of Chrm1 2 0.29 0.52 0.7
46 INT265153 Positive_regulation of Negative_regulation of Chrm1 1 0.09 0.09 0.69
47 INT149689 Binding of Chrm3 3 0.24 1.54 0.65
48 INT193037 Regulation of Chrm2 7 0.19 8.82 0.64
49 INT35282 Positive_regulation of Chrm4 4 0.45 0.81 0.64
50 INT88078 Negative_regulation of Chrm4 3 0.25 2.74 0.61
51 INT212816 Positive_regulation of Chrm5 1 0.46 0.19 0.6
52 INT104335 Localization of Chrm3 2 0.62 0.58 0.57
53 INT172502 Binding of Chrm3 2 0.08 3.3 0.53
54 INT104336 Positive_regulation of Localization of Chrm3 1 0.38 0.14 0.5
55 INT45395 Localization of CHRM1 2 0.73 0.4 0.41
56 INT265176 Regulation of Positive_regulation of Chrm1 1 0.10 0 0.41
57 INT193055 Positive_regulation of CHRM2 5 0.03 2.19 0.4
58 INT57849 Positive_regulation of Binding of Chrm1 1 0.06 0.25 0.4
59 INT265167 Phosphorylation of Chrm1 1 0.18 0.08 0.39
60 INT57848 Positive_regulation of Gene_expression of Chrm1 1 0.08 0.25 0.38
61 INT183266 Negative_regulation of CHRM4 2 0.30 0 0.37
62 INT212763 Regulation of CHRM4 1 0.02 0.42 0.36
63 INT95029 Transcription of Chrm4 1 0.25 0 0.36
64 INT265174 Positive_regulation of Positive_regulation of Chrm1 1 0.11 0 0.35
65 INT33716 Negative_regulation of Positive_regulation of CHRM1 1 0.00 0 0.35
66 INT45394 Positive_regulation of Localization of CHRM1 1 0.27 0 0.32
67 INT45393 Regulation of Localization of CHRM1 1 0.25 0 0.32
68 INT201347 Negative_regulation of Gene_expression of Chrm3 4 0.30 2.48 0.31
69 INT354016 Positive_regulation of Positive_regulation of CHRM2 1 0.03 0.79 0.31
70 INT265152 Regulation of Localization of Chrm1 1 0.10 0 0.28
71 INT227951 Regulation of Chrm4 1 0.18 1.45 0.26
72 INT238366 Positive_regulation of Positive_regulation of Chrm2 1 0.05 0.82 0.26
73 INT227952 Binding of Chrm2 9 0.19 5.19 0.25
74 INT265169 Negative_regulation of Negative_regulation of Chrm1 1 0.08 0 0.25
75 INT228093 Regulation of Gene_expression of Chrm2 1 0.22 0.4 0.19
76 INT227948 Localization of Chrm5 1 0.69 0.28 0.17
77 INT227950 Negative_regulation of Localization of Chrm5 1 0.39 0.28 0.17
78 INT227040 Negative_regulation of CHRM2 5 0.14 1.67 0.15
79 INT193072 Transcription of CHRM2 2 0.41 3.39 0.15
80 INT228087 Transcription of Chrm2 2 0.29 1.08 0.14
81 INT238363 Positive_regulation of Transcription of Chrm2 1 0.05 1.05 0.13
82 INT196243 Localization of CHRM4 1 0.56 0 0.13
83 INT193067 Positive_regulation of Transcription of CHRM2 1 0.03 1.03 0.13
84 INT196226 Negative_regulation of Localization of CHRM4 1 0.30 0 0.13
85 INT196242 Positive_regulation of Localization of CHRM4 1 0.35 0 0.13
86 INT228084 Localization of Chrm2 8 0.36 1.54 0.11
87 INT132742 Localization of Chrm1 2 0.51 0.2 0.1
88 INT303728 Gene_expression of Chrm3 1 0.14 0.98 0.09
89 INT303727 Positive_regulation of Gene_expression of Chrm3 1 0.10 0.99 0.09
90 INT303748 Regulation of Gene_expression of CHRM1 1 0.01 0.95 0.09
91 INT62787 Negative_regulation of Binding of Chrm1 1 0.43 0.09 0.07
92 INT193058 Negative_regulation of Gene_expression of CHRM2 2 0.28 1.01 0.06
93 INT35281 Binding of Chrm4 1 0.00 0.1 0.06
94 INT227041 Localization of CHRM2 2 0.49 0.34 0.05
95 INT282797 Negative_regulation of Binding of Chrm2 1 0.19 0 0.05
96 INT227039 Binding of CHRM2 1 0.01 0.24 0.05
97 INT201344 Positive_regulation of Gene_expression of Chrm3 1 0.19 0.34 0.04
98 INT350314 Negative_regulation of Negative_regulation of Chrm1 1 0.29 0 0.04
99 INT262975 Transcription of CHRM4 1 0.34 0.07 0.03
100 INT350318 Negative_regulation of Localization of Chrm1 1 0.29 0 0.03
101 INT262973 Transcription of CHRM1 1 0.35 0.07 0.03
102 INT209662 Negative_regulation of Gene_expression of CHRM1 1 0.20 0.91 0
103 INT262974 Positive_regulation of Gene_expression of CHRM2 1 0.30 0.32 0
104 INT262977 Positive_regulation of Localization of CHRM2 1 0.33 0.1 0
105 INT303731 Positive_regulation of Binding of Chrm1 1 0.13 0.69 0
106 INT302921 Negative_regulation of Regulation of Chrm2 1 0.05 1.22 0
107 INT228086 Positive_regulation of Negative_regulation of Chrm2 1 0.21 0.24 0
108 INT228099 Regulation of Regulation of Chrm2 1 0.19 0.08 0
109 INT209687 Negative_regulation of Negative_regulation of CHRM1 1 0.20 0.3 0
110 INT84493 Positive_regulation of Positive_regulation of Chrm3 1 0.33 0 0
111 INT202865 Regulation of Gene_expression of Chrm3 1 0.07 0.37 0
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