GO:0017034

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Name Rap guanyl-nucleotide exchange factor activity
Categary Function
Go Slim No
Go Link GO:0017034
Unique Molecular Interactions 11
Total Molecular Interactions 14
Total Single Events 152
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Rap guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported for Rap guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37
2 INT241742 Negative_regulation of Sdhb Regulation of Rapgef5 1 0.02 0.39 0.33
3 INT241740 Sdhb Regulation of Rapgef5 1 0.02 0.34 0.32
4 INT96045 Capn1 Regulation of Rasgrp1 1 0.01 0.44 0.09
5 INT291621 RAPGEF5 Regulation of CSTA 1 0.04 0.43 0.03
6 INT96044 Rasgrp1 Positive_regulation of Gene_expression of Nos2 1 0.14 0.05 0
7 INT115368 Binding of GDNF and RAPGEF5 1 0.32 0 0
8 INT345287 Binding of SCN10A and RAPGEF5 1 0.01 0.67 0
9 INT96046 Rasgrp1 Negative_regulation of Mpo 1 0.23 0.06 0
10 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0
11 INT96043 Rasgrp1 Negative_regulation of Sdcbp 1 0.02 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Rap guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported in Rap guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55
2 INT37485 Regulation of RAPGEF5 10 0.44 6.64 1.51
3 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41
4 INT96039 Regulation of Rasgrp1 1 0.37 0.44 1.36
5 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04
6 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93
7 INT241722 Gene_expression of Rapgef5 1 0.24 1.34 0.81
8 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43
9 INT270743 Negative_regulation of Localization of RAPGEF5 1 0.11 1.6 0.27
10 INT96038 Positive_regulation of Rasgrp1 2 0.30 0.55 0.17
11 INT279950 Positive_regulation of Positive_regulation of RAPGEF5 1 0.24 1.56 0.1
12 INT293085 Regulation of Rapgef5 1 0.26 0.31 0.09
13 INT164479 Positive_regulation of Gene_expression of RAPGEF5 2 0.49 1.3 0.08
14 INT4680 Positive_regulation of Negative_regulation of RAPGEF5 2 0.45 1.66 0.07
15 INT11119 Negative_regulation of Gene_expression of RAPGEF5 1 0.41 0.89 0.06
16 INT241736 Negative_regulation of Rapgef5 2 0.57 1 0.04
17 INT354543 Regulation of Gene_expression of RAPGEF5 1 0.03 0.82 0
18 INT188966 Regulation of Positive_regulation of RAPGEF5 1 0.36 0.38 0
19 INT279951 Negative_regulation of Negative_regulation of RAPGEF5 1 0.18 2.57 0
20 INT293086 Positive_regulation of Rapgef5 1 0.67 0.33 0
21 INT270739 Negative_regulation of Positive_regulation of RAPGEF5 1 0.04 0.36 0
22 INT210067 Protein_catabolism of RAPGEF5 1 0.05 0.24 0
23 INT198960 Transcription of RAPGEF5 1 0.07 1.59 0
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